Abstract:
:Autoimmune diseases refer to a spectrum of diseases characterized by an active immune response against the host, which frequently involves increased autoantibody production. The pathogenesis of autoimmune diseases is multifactorial and the exploitation of novel effective treatment is urgent. Capsaicin is a nutritional factor, the active component of chili peppers, which is responsible for the pungent component of chili pepper. As a stimuli, capsaicin selectively activate transient receptor potential vanilloid subfamily 1(TRPV1) and exert various biological effects. This review discusses the effect of capsaicin through its receptor on the development and modulation of autoimmune diseases, which may shed light upon potential therapies in capsaicin-targeted approaches.
journal_name
Autoimmun Revjournal_title
Autoimmunity reviewsauthors
Deng Y,Huang X,Wu H,Zhao M,Lu Q,Israeli E,Dahan S,Blank M,Shoenfeld Ydoi
10.1016/j.autrev.2016.01.009subject
Has Abstractpub_date
2016-05-01 00:00:00pages
451-6issue
5eissn
1568-9972issn
1873-0183pii
S1568-9972(16)30005-2journal_volume
15pub_type
杂志文章,评审abstract:OBJECTIVE:To assess the effectiveness of anti-TNFalpha agents by analysing the principal clinical outcomes in patients with active rheumatoid arthritis (RA). METHODS:1010 patients who received no clinical benefit from previous treatment with methotrexate and/or other DMARDs, were subsequently treated with one or more ...
journal_title:Autoimmunity reviews
pub_type: 临床试验,杂志文章
doi:10.1016/j.autrev.2008.11.001
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Autoimmunity reviews
pub_type: 杂志文章
doi:10.1016/j.autrev.2006.09.011
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
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journal_title:Autoimmunity reviews
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更新日期:2014-07-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2018.09.005
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2005.10.005
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2012.05.001
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journal_title:Autoimmunity reviews
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