Abstract：
:The immune system and the neuroendocrine system machinery modulate each other, including life events-induced stresses and interpersonal conflicts, promoting the synthesis of proinflammatory cytokines, overproduction of which influence behaviour. In addition, the balance of systemic and local pro-inflammatory cytokines to systemic and local anti-inflammatory cytokines, is impaired to such an extent that, in genetically-predisposed individuals, this aberrancy may lead to autoimmune diseases. Occupational stress likely influences their onset. For example, subclinical autoimmune hypothyroidism has been identified in numerous shift-workers of an Italian hospital. Such a threat impacts the policy of health surveillance of the workers and requires dedication of further studies to the relationship between occupational stress and autoimmunity.
journal_name
Autoimmun Revjournal_title
Autoimmunity reviewsauthors
Boscolo P,Youinou P,Theoharides TC,Cerulli G,Conti Pdoi
10.1016/j.autrev.2007.12.003subject
Has Abstractpub_date
2008-02-01 00:00:00pages
340-3issue
4eissn
1568-9972issn
1873-0183pii
S1568-9972(07)00211-Xjournal_volume
7pub_type
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journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
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更新日期：2010-01-01 00:00:00
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pub_type： 杂志文章
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journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
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更新日期：2015-12-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,meta分析
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pub_type： 杂志文章,评审
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journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
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journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
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更新日期：2004-11-01 00:00:00
abstract：:Experimental analyses and literature survey reveal low-redundancy to the host proteins as a common denominator of immunogenic sequences mapped along tumor-, autoimmune-, and infectious disease-associated-proteins. The hypothesis that immunogenicity of peptide sequences is linked to proteomic redundancy is discussed. ...
journal_title：Autoimmunity reviews
pub_type： 杂志文章,评审
doi：10.1016/j.autrev.2006.09.004
更新日期：2007-04-01 00:00:00
