Glucomannan utilization operon of Bacillus subtilis.

Abstract:

:This study characterizes the glucomannan utilization operon (gmuBACDREFG, formerly ydhMNOPQRST) of Bacillus subtilis. Transcription of the operon is induced by konjac glucomannan and requires the last mannanase gene (gmuG). Cellobiose and mannobiose, possible degradation products of glucomannan by GmuG, are strong inducers of transcription. It is shown that an internal regulator gene (gmuR) encodes a repressor of the operon, as disruption of this gene enhances transcription of the operon in the absence of inducers. The expression of the glucomannan utilizing operon of B. subtilis is thus induced by degraded glucomannan products, and repressed by an internal repressor.

journal_name

FEMS Microbiol Lett

authors

Sadaie Y,Nakadate H,Fukui R,Yee LM,Asai K

doi

10.1111/j.1574-6968.2007.01018.x

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

103-9

issue

1

eissn

0378-1097

issn

1574-6968

pii

FML1018

journal_volume

279

pub_type

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