Abstract:
BACKGROUND:The aim of the current study was to investigate levels of adenosine deaminase in plasma of patients with hydatidiform mole. METHODS:Plasma adenosine deaminase levels were determined in 17 women with normal pregnant course, in 17 women with hydatidiform mole, and in 17 non-pregnant healthy volunteers. RESULTS:Mean adenosine deaminase activity in the hydatidiform mole group was 121.5+/-24.8 U/L, significantly higher than in the pregnant control (7.8+/-6.5 U/L; p<0.0001) and non-pregnant control groups (6.4+/-7.4 U/L; p<0.0001). A cutoff level of 40.5 U/L was found, with both sensitivity and specificity of 100%. CONCLUSIONS:Adenosine deaminase may play a role in the development of hydatidiform mole.
journal_name
Clin Chem Lab Medjournal_title
Clinical chemistry and laboratory medicineauthors
Engin-Ustün Y,Ustün Y,Karabulut AB,Doğan K,Meydanli MM,Sezgin Bdoi
10.1515/CCLM.2007.010subject
Has Abstractpub_date
2007-01-01 00:00:00pages
78-81issue
1eissn
1434-6621issn
1437-4331journal_volume
45pub_type
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