Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval strongyloides stercoralis in mice.

abstract：:Whereas infections of macrophages by promastigote forms of Leishmania mexicana pifanoi induce the production of superoxide, infections by amastigotes barely induce superoxide production. Several approaches were employed to gain insight into the mechanism by which amastigotes avoid eliciting superoxide production. Firs...

journal_title：Infection and immunity

authors： Pham NK,Mouriz J,Kima PE

更新日期：2005-12-01 00:00:00

abstract：:The induction of interleukin-8 (IL-8) in vitro has been suggested to correlate with the reactogenicity of Vibrio cholerae vaccine candidates. V. cholerae vaccine candidate 638, a hemagglutinin protease/hap-defective strain, was recently reported to be well tolerated in human volunteers, suggesting a role for Hap in re...

journal_title：Infection and immunity

authors： Zhou X,Gao DQ,Michalski J,Benitez JA,Kaper JB

更新日期：2004-01-01 00:00:00

abstract：:Rickettsia rickettsii infection of endothelial cells is manifested in very distinctive changes in cell morphology, consisting of extensive dilatation of the membranes of the endoplasmic reticulum and outer nuclear envelope and blebbing of the plasma membrane, as seen by transmission electron microscopy (D. J. Silverma...

journal_title：Infection and immunity

authors： Eremeeva ME,Silverman DJ

更新日期：1998-05-01 00:00:00

abstract：:Severe combined immunodeficient (SCID)-beige mice inoculated with the intracellular parasite Eimeria papillata produced significantly more oocysts during primary infections than inoculated immunodeficient SCID mice. Therefore, the addition of the beige mutation, which detrimentally affects neutrophil and natural kille...

journal_title：Infection and immunity

authors： Schito ML,Barta JR

更新日期：1997-08-01 00:00:00

abstract：:Several group B streptococcal products have been previously found to stimulate human monocytes to produce tumor necrosis factor alpha. In order to identify the receptors involved in these responses, monocytes were stimulated with purified group- or type-specific carbohydrates or lipoteichoic acid in the presence of an...

journal_title：Infection and immunity

authors： Cuzzola M,Mancuso G,Beninati C,Biondo C,von Hunolstein C,Orefici G,Espevik T,Flo TH,Teti G

更新日期：2000-02-01 00:00:00

abstract：:Oral administration of polymyxin to specific-pathogen-free C3H/Law mice which with previously contaminated with gram-negative bacteria resulted in complete suppression of cecal gram-negative bacteria. Suppression of cecal gram-negative bacteria was accompanied by reduction of the cecal endotoxin concentration from 10 ...

journal_title：Infection and immunity

authors： Goris H,de Boer F,van der Waaij D

更新日期：1985-11-01 00:00:00

abstract：:Peritoneal exudate T lymphocytes from Listeria monocytogenes-immune mice in the presence of the homologous antigen (heat-killed L. monocytogenes) and normal macrophages showed L. monocytogenes-specific proliferative responses. Proliferation was inhibited by macrophages from L. monocytogenes- or Corynebacterium parvum-...

journal_title：Infection and immunity

authors： Kaufmann SH,Simon MM,Hahn H

更新日期：1982-12-01 00:00:00

abstract：:The enterotoxin of Shigella dysenteriae I produces fluid and electrolyte secretion in the rabbit ileum. These present studies were designed to evaluate nonelectrolyte transport in rabbit ileal mucosa exposed to Shigella enterotoxin. Both 10 mM galactose and 5 mM L-alanine absorptions were significantly impaired in ent...

journal_title：Infection and immunity

authors： Binder HJ,Whiting DS

更新日期：1977-05-01 00:00:00

abstract：:Nucleotide-binding oligomerization domain (NOD) protein 1 (NOD1) and NOD2 are pathogen recognition receptors that sense breakdown products of peptidoglycan (PGN) (muropeptides). It is shown that a number of these muropeptides can induce tumor necrosis factor alpha (TNF-alpha) gene expression without significant TNF-al...

journal_title：Infection and immunity

authors： Wolfert MA,Roychowdhury A,Boons GJ

更新日期：2007-02-01 00:00:00

abstract：:In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport chang...

journal_title：Infection and immunity

authors： Fernández Miyakawa ME,Pistone Creydt V,Uzal FA,McClane BA,Ibarra C

更新日期：2005-12-01 00:00:00

abstract：:A modified version of the Bacteroides fragilis transposon Tn4400, designated Tn4400', enabling rapid isolation and analysis of B. fragilis mutants has been constructed. To identify potential virulence factors, Tn4400'-generated mutants were screened by a new method; this resulted in the isolation of 21 mutant strains ...

journal_title：Infection and immunity

authors： Tang YP,Malamy MH

更新日期：2000-01-01 00:00:00

abstract：:Protective immunity to Plasmodium falciparum malaria acquired after natural exposure is largely antibody mediated. IgG-specific P. falciparum EMP1 (PfEMP1) proteins on the infected erythrocyte surface are particularly important. The transient antibody responses and the slowly acquired protective immunity probably refl...

journal_title：Infection and immunity

authors： Ampomah P,Stevenson L,Ofori MF,Barfod L,Hviid L

更新日期：2014-05-01 00:00:00

abstract：:The immune response of mice to live, heat-killed, or autoclaved Mycobacterium leprae was investigated. After sensitization with 10(7) organisms in each group, recipient mice were transfused with the sensitized splenocytes 28 days later. A selected number of these mice were infected with 5 X 10(3) M. leprae, and the re...

journal_title：Infection and immunity

authors： Graham L Jr,Navalkar RG

更新日期：1984-01-01 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) is a noninvasive food-borne pathogen that colonizes the distal ileum and colon. Proteins encoded in the EHEC locus of enterocyte effacement (LEE) pathogenicity island are known to contribute to this pathogen's adherence to epithelial cells and intestinal colonization. The role...

journal_title：Infection and immunity

authors： Ho TD,Davis BM,Ritchie JM,Waldor MK

更新日期：2008-05-01 00:00:00

abstract：:We have developed an animal model for studying mycobacterial pathogenesis using Mycobacterium marinum and the goldfish, Carassius auratus. Goldfish are injected intraperitoneally with doses between 10(2) and 10(9) CFU of M. marinum organisms. Depending on the dose of M. marinum organisms administered, an acute or chro...

journal_title：Infection and immunity

authors： Talaat AM,Reimschuessel R,Wasserman SS,Trucksis M

更新日期：1998-06-01 00:00:00

abstract：:The purpose of our study was to characterize the properties of the interaction of pertussis toxin with human polymorphonuclear leukocytes for the modulation of leukotriene generation and metabolism. The cells were stimulated with either the Ca ionophore A23187, opsonized zymosan, or the bacterial peptide formyl-methio...

journal_title：Infection and immunity

authors： Hensler T,Raulf M,Megret F,Alouf JE,König W

更新日期：1989-10-01 00:00:00

abstract：:Helicobacter infections are present in approximately 50% of humans, causing severe illnesses such as gastritis and malignancies. Dendritic cells (DC) are critical antigen-presenting cells which link innate and adaptive immune responses. The mechanism of dendritic cell regulation in Helicobacter-induced gastritis is po...

journal_title：Infection and immunity

authors： Drakes ML,Czinn SJ,Blanchard TG

更新日期：2006-08-01 00:00:00

abstract：:Human immunodeficiency virus (HIV)-infected individuals are predisposed to recurrent oral candidiasis, and, although it has been assumed that this is because of deficient mucosal immune responses, this has not been properly established. The present study aimed to compare the concentrations and secretion rates of immun...

journal_title：Infection and immunity

authors： Coogan MM,Sweet SP,Challacombe SJ

更新日期：1994-03-01 00:00:00

abstract：:Of 51 patients with herpes simplex labialis, 50 had detectable interferon (IFN) in samples of lesion vesicle fluid. The median titer of vesicle fluid IFN was 8,200 U. and the range of values was 400 to 63,600 U. The amount of vesicle fluid IFN was correlated with lesion age (r = 0.32, P = 0.024) and vesicle fluid viru...

journal_title：Infection and immunity

authors： Spruance SL,Green JA,Chiu G,Yeh TJ,Wenerstrom G,Overall JC Jr

更新日期：1982-06-01 00:00:00

abstract：:The cyst cell wall β-glucans of Pneumocystis have been shown to stimulate immune responses in lung epithelial cells, dendritic cells, and alveolar macrophages. Little is known about how the trophic life forms, which do not have a fungal cell wall, interact with these innate immune cells. Here, we report differences in...

journal_title：Infection and immunity

authors： Evans HM,Bryant GL 3rd,Garvy BA

更新日期：2016-11-01 00:00:00

abstract：:Mucosa-associated invariant T (MAIT) cells are an innate-like T cell subset in mammals that recognize microbial vitamin B metabolites presented by the evolutionarily conserved major histocompatibility complex class I (MHC I)-related molecule, MR1. Emerging data suggest that MAIT cells may be an attractive target for v...

journal_title：Infection and immunity

authors： Vorkas CK,Levy O,Skular M,Li K,Aubé J,Glickman MS

更新日期：2020-12-15 00:00:00

abstract：:Toxic shock syndrome (TSS) toxin 1 (TSST1) is produced by strains of Staphylococcus aureus associated with TSS. Purified TSST1 induces in rabbits a shock-like illness with many features similar to TSS in humans. These symptoms were also induced by TSST1-producing bacteria in diffusion chambers implanted in the rabbit ...

journal_title：Infection and immunity

authors： de Azavedo JC,Foster TJ,Hartigan PJ,Arbuthnott JP,O'Reilly M,Kreiswirth BN,Novick RP

更新日期：1985-10-01 00:00:00

abstract：:We studied the oligosaccharides (OS) of outer membrane lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis. OS from the LOS of an individual neisserial strain always eluted from Sephadex G-50S as multiple peaks; the polyacrylamide gel elution profiles were nearly identical to the polyacrylam...

journal_title：Infection and immunity

authors： Griffiss JM,O'Brien JP,Yamasaki R,Williams GD,Rice PA,Schneider H

更新日期：1987-08-01 00:00:00

abstract：:Antisera were produced by inoculation of mycoplasma cells grown in PPLO broth supplemented with rabbit serum alone or rabbit serum plus Freund complete or incomplete adjuvant. By using an enzyme-linked immunosorbent assay, immunoglobulin G antibodies to cholesterol were detected in antisera to mycoplasmas (Mycoplasma ...

journal_title：Infection and immunity

authors： Watanabe T,Kumazawa T

更新日期：1991-06-01 00:00:00

abstract：:A novel immunobiologically active fraction was prepared from a phenol-water extract of Prevotella intermedia ATCC 25611 by Sephadex G-100 column chromatography. The fraction consisted mainly of carbohydrate and protein and was devoid of fatty acid. The fraction showed high-molecular-weight bands (10,000 to 12,000) on ...

journal_title：Infection and immunity

authors： Iki K,Kawahara K,Sawamura S,Arakaki R,Sakuta T,Sugiyama A,Tamura H,Sueda T,Hamada S,Takada H

更新日期：1997-11-01 00:00:00

abstract：:The mechanism of activation of intestinal guanylate cyclase by Escherichia coli heat-stable enterotoxin (STa) has been studied by using isolated rat intestinal epithelial cells and purified brush border membrane (BBM) preparations. Inhibitors of prostaglandin biosynthesis, quinacrine and 5,8,11,14-eicosatetraynoic aci...

journal_title：Infection and immunity

authors： Dreyfus LA,Jaso-Friedmann L,Robertson DC

更新日期：1984-05-01 00:00:00

abstract：:Spotted fever group rickettsiae are known to produce distinct plaque phenotypes. Strains that cause lytic infections in cell culture form clear plaques, while nonlytic strains form opaque plaques in which the cells remain intact. Clear plaques have historically been associated with more-virulent species or strains of ...

journal_title：Infection and immunity

authors： Clark TR,Ellison DW,Kleba B,Hackstadt T

更新日期：2011-04-01 00:00:00

abstract：:Three open reading frames (ORFs) were identified by a genome walking strategy in the genomes of serotype M49 group A streptococcal (GAS) strains CS101 and 591. These ORFs were located between the mga core regulon and the dipeptide permease operon. The deduced amino acid (aa) sequences contained signature sequences ind...

journal_title：Infection and immunity

authors： Elsner A,Kreikemeyer B,Braun-Kiewnick A,Spellerberg B,Buttaro BA,Podbielski A

更新日期：2002-09-01 00:00:00

abstract：:Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...

journal_title：Infection and immunity

authors： Forsum U,Forsgren A,Hjelm E

更新日期：1972-10-01 00:00:00

abstract：:Restoration of the ability of hypogammaglobulinemic serum to support opsonophagocytosis and intracellular killing of Bacteroides fragilis and Bacteroides thetaiotaomicron by human polymorphonuclear leukocytes was achieved by supplementation with normal human immunoglobulin M, but not with normal human immunoglobulin G...

journal_title：Infection and immunity

authors： Bjornson AB,Bjornson HS,Kitko BP

更新日期：1980-05-01 00:00:00