Listeria monocytogenes protein p60 affects hemolytic activity and uptake of bacteria by macrophages.

Abstract:

:Bacillus subtilis strains expressing listeriolysin O (LLO) and simultaneously LLO and p60 protein were constructed. The effect of p60 protein on hemolytic activity and on the invasion of professional phagocytes was demonstrated in the absence of other virulence factors of L. monocytogenes. The hemolytic activity of LLO in the presence of p60 protein decreased which indicates that p60 promoted adhesion and subsequent invasion of professional phagocytes.

journal_title

Folia microbiologica

authors

Krawczyk-Balska A,Markiewicz Z,Bielecki J

doi

10.1007/BF02931440

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

515-8

issue

6

eissn

0015-5632

issn

1874-9356

journal_volume

50

pub_type

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