Endogenous digoxin-like immunoreactivity in follicular fluid and in vitro fertilization.

Abstract:

:Plasma digoxin-like immunoreactive factor (DLIF) has been detected in various pathophysiological conditions associated with volume expansion. In this study, using radioimmunoassay, we confirmed the existence of high levels of DLIF in the stimulated follicular fluid, a rapidly volume-expanding biological model. The concentration of the various fractions of DLIF in follicular fluid was 2-9 times higher than in plasma, suggesting local concentration or production. No difference in concentration was observed between follicles containing fertilized oocytes and follicles with unfertilized oocytes. The role of DLIF in follicular homeostasis remains to be further investigated.

journal_name

Gynecol Obstet Invest

authors

Jakobi P,Krivoy N,Eibschitz I,Ziskind G

doi

10.1159/000293029

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

193-5

issue

4

eissn

0378-7346

issn

1423-002X

journal_volume

32

pub_type

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