Abstract:
:The theory that the Th1 and Th2 cell ratio shifts towards Th2 dominance during pregnancy may improve fetal survival has gained support from recent studies. Also, the variation in the Th1/Th2 cell ratio is reportedly associated with intrauterine growth retardation and preeclampsia. On the basis of these findings, the analysis of the Th1/Th2 balance may be useful in predicting severe complications during pregnancy. However, simple methods for the analysis of Th1/Th2 balance are presently not available. Recently, it has been reported that regulation of CD26 cell surface expression correlates with the production of Th1-like cytokines. On the other hand, previous studies proposed that the sCD30 molecule is an activation marker useful for evaluation of a Th2 immune response. It is, therefore, possible that the analysis of the Th1/Th2 balance during pregnancy by measuring plasma sCD26 and sCD30 simultaneously is a simple and useful method. We herein demonstrate that combined analysis of sCD26 and sCD30 is a potent surrogate tool to evaluate the Th1/Th2 balance during pregnancy.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Hoshimoto K,Ohta N,Ohkura T,Inaba Ndoi
10.1159/000010328keywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
260-3issue
4eissn
0378-7346issn
1423-002Xpii
10328journal_volume
50pub_type
临床试验,杂志文章abstract:AIMS:To summarize the clinical features, perioperative management and maternal and neonatal outcomes of patients with acute fatty liver of pregnancy (AFLP) and to discuss the management of anesthesia in these patients. METHODS:This study was a retrospective review over a period of 5 years and 9 months; 28 cases from t...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000351565
更新日期:2013-01-01 00:00:00
abstract::A decade of perinatal audit in the Maputo Central Hospital is reviewed with the objective of addressing the potential value of the audit process in monitoring the different constituents of morbidity and mortality in the perinatal period. The perinatal mortality showed a significant but transient change during the obse...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292637
更新日期:1993-01-01 00:00:00
abstract::The function of adrenoceptors in the female genital tract was tested estimating the uptake of 3H-noradrenaline (3H-NA) in vitro in oviductal, uterine arterial and myometrial tissue samples obtained from 74 women. The highest 3H-NA value, 64 +/- 5 ng/g, was in the oviduct (p less than 0.001 vs. uterine artery and myome...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293673
更新日期:1988-01-01 00:00:00
abstract::Proliferative activity of uterine leiomyomas from premenopausal (n = 44) and postmenopausal (n = 12) women was investigated by automatic image analysis on frozen tissue sections using immunohistochemistry with anti-proliferating cell nuclear antigen antibody. The quantitative proliferation index (QPI) in premenopausal...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292738
更新日期:1992-01-01 00:00:00
abstract::In vitro production of progesterone and estradiol by human corpora lutea of different ages was evaluated in the presence or absence of human chorionic gonadotrophin (HCG). Progesterone production by the luteal tissue was enhanced by as little as 0.1 IU/ml HCG and maximally stimulated by approximately 10 IU/ml HCG. Est...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293698
更新日期:1988-01-01 00:00:00
abstract::The scanning electron microscopy by virtue of its high resolution topographic reproduction of epithelial surfaces lining the female genital tract, provides unique information toward understanding the anatomy and physiology of the female reproductive system. The human Fallopian ectopic pregnancy is an urgent gynecologi...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299226
更新日期:1983-01-01 00:00:00
abstract::Lipid peroxidation and the antioxidant system were investigated in the plasma and placenta of normal and preeclamptic pregnant women. A significant increase in thiobarbituric acid reactive substance (TBARS), significant decreases in total thiol (t-SH) content and superoxide dismutase (SOD) activity, and unchanged vita...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009994
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIM:We aimed to assess the value of early laparoscopic therapy in management of tubo-ovarian abscess (TOA) or pelvic abscess. METHODS:This was a retrospective study of all consecutive patients who were initially diagnosed with TOA or pelvic abscess at the local hospital between January 2010 and December 201...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000493855
更新日期:2019-01-01 00:00:00
abstract::Abdominal pregnancy is a very rare and serious type of extrauterine gestation that accounts for approximately 0.003% of all ectopic pregnancies. Omental pregnancy, an extremely rare form of abdominal pregnancy, can be primary or secondary to a tubal pregnancy that aborts out of the fimbria and reimplants in the perito...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000070188
更新日期:2003-01-01 00:00:00
abstract::Bone turnover in pregnant women with McCune-Albright syndrome may be affected by both the syndrome and pregnancy. This study evaluated changes in biochemical bone turnover markers in pregnant women with the syndrome. Serum calcium, phosphorus, 1,25-dihydroxyvitamin D (1,25-(OH)2D), intact osteocalcin (I-OC) and alkali...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000085535
更新日期:2005-01-01 00:00:00
abstract::A small dermatan sulphate proteoglycan has been isolated from the human uterine cervix. The concentration of this proteoglycan has been shown to decrease during pregnancy. To study the mechanism behind this change fibroblasts from the human uterine cervix were established in culture. Their synthesis and secretion of p...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299026
更新日期:1985-01-01 00:00:00
abstract::Highly evacuated (980 mbar) wound drainage systems according to Redon were used in 100 gynecologic laparotomies. In 96% of cases, no flask exchange was required before the system was removed. Bacteriological specimens from various locations of the Redon system showed minimal colonization with pathogenic bacteria. No c...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293758
更新日期:1988-01-01 00:00:00
abstract:AIMS:To construct in vitro models of normal uterine arterial vascular network through vascular corrosion casting and explore their characteristics and clinical significances. METHODS:Three sets of uterus, vagina and bilateral adnexa were perfused and cast via uterine artery and ovarian artery, using 25, 20 and 15% chl...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000245941
更新日期:2010-01-01 00:00:00
abstract::In vitro experiments using isolated rings and perfused segments of human chorionic veins, were designed to determine the effects of serotonin and their interaction with PGF2 alpha on vascular tension and perfusion pressure. These vessels responded vigorously with high sensitivity to the vasoconstrictor effects of sero...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292671
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND/AIMS:Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being. The pathophysiology and epidemiology of fibroids are poorly understood. Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigat...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000114250
更新日期:2008-01-01 00:00:00
abstract::The aim of the present study was to investigate whether women with endometriosis displayed a decreased lymphokine-activated killer (LAK) activity. In 15 women with and 7 women without endometriosis the cytotoxicity against four different tumor cell lines--K562, the endometrium carcinomas AN3CA and RL95, the natural-ki...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292556
更新日期:1994-01-01 00:00:00
abstract::Oviduct fluid was collected from 24 mature female rabbits in estrus fitted with a copper intrauterine device (IUD) in one of the uterine horns by laparotomy and examined for total sugar and protein content. The percentage of total sugar in the dry protein-containing material from the experimental side was 7.3 compared...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299449
更新日期:1982-01-01 00:00:00
abstract::The concentrations of atrial natriuretic peptide (ANP) and its presumed second messenger, cyclic guanosine-3',5'-monophosphate (cGMP) were determined in maternal plasma and amniotic fluid. Samples were obtained from normal and pathological pregnancies revealing hydramnios or severe Rh incompatibility between week 16 o...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293311
更新日期:1990-01-01 00:00:00
abstract::Semistructured interviews were made among a random sample of applicants for abortion in Stockholm, when legal abortion on demand had been available in Sweden for 10 years. One hundred and twenty women were interviewed, 75 of them having their first abortion and 45 having a repeat abortion. The use of contraceptives wa...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292572
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy, feasibility, operative time and possible complications of a modified technique of hysteroscopic removal of large submucus myomata versus traditional morcellation technique, and to assess the efficacy of preoperative sonohysterography (SHG). DESIGN:A prospective comparative study. SE...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000074451
更新日期:2003-01-01 00:00:00
abstract::We measured three selected components of the fibrinolytic system in amniotic fluid of 36 parturient women, i.e. the antigen of tissue plasminogen activator (tPA) and antigens of plasminogen activator inhibitor of type 1 (PAI-1) and type 2 (PAI-2). The ELISA method was used. During labour, the level of each of the stud...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292387
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of five methods including the ThinPrep cytological test (TCT), liquid-based cytology, the human papillomavirus (HPV) test, detection of the TERC and C-MYC genes and visual inspection with acetic acid/Lugol's iodine (VIA/VILI) for opportunistic cervical cancer screening, and to ex...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000371760
更新日期:2015-01-01 00:00:00
abstract:AIM:To determine factors associated with intrapartum fever and to examine associated maternal and neonatal outcomes. METHODS:Retrospective study of patients between 360/7 and 420/7 gestational weeks who entered spontaneous or induced active labor and developed temperature ≥38°C; a similar group that did not develop fe...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000453611
更新日期:2017-01-01 00:00:00
abstract::An extremely rare case of partial hydatidiform mole located in the right Fallopian tube was diagnosed by ultrasonography and computed tomography. The lesion was excised, and the human chorionic gonadotropin (HCG) level in early morning urine fell below 1,000 IU/ml on postoperative day 11, and the serum HCG-beta level ...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292708
更新日期:1993-01-01 00:00:00
abstract::The electric activity of the ovary was studied in 13 female mongrel dogs aiming at characterizing a normal electro-oophorogram (EOOG). Two monopolar silver-silver chloride electrodes were sutured under anesthesia to the ovary of the bitches which were in the anestrus phase of the estrous cycle. A daily recording sessi...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010012
更新日期:1998-08-01 00:00:00
abstract::The study describes Kock's continent ileostomy in 2 females, both of whom were suffering from tubal infertility. Appropriate placement of the abdominal pouch, permitting in vitro fertilization embryo transfer treatment, was present in 1 patient. In the other patient, an ultrasonographic examination demonstrated the po...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293324
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVES:Assessment of the contraceptive effectiveness of pure estradiol pellets implanted annually under the skin, thus avoiding the 'first passage phenomenon' through the liver, using a modification of Emperaire and Greenblatt's method. STUDY DESIGN:228 women wishing birth control for 1 year or more were included....
journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章
doi:10.1159/000082652
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:Isotretinoin is used in acne vulgaris treatment for more than 20 years. Isotretinoin has serious side effects on many organs, but there are no comprehensive studies investigating its possible toxic effects on reproductive organs. Thus, we aimed to investigate the possible toxic effects of isotretinoin adminis...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000510031
更新日期:2020-01-01 00:00:00
abstract::Our purpose was to determine whether intrauterine sonography with high-frequency, real-time miniature transducer (20 MHz) is useful for the diagnosis of gynecologic disorders. The study consisted of 37 women: 8 normal volunteers, 2 with molar pregnancy, 4 fibromyoma, 4 endometrial polyp, 1 intrauterine adhesion, 1 sep...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010072
更新日期:1999-01-01 00:00:00
abstract::Severe fetal distress was produced in 16 fetal dogs by successive and/or prolonged occlusion of the maternal abdominal aorta in an acute surgical preparation, and was characterized in fetal arterial blood of 7.06 for pH, 10 mm Hg for O2, 127 mm Hg for CO2, and fetal heart rate decelerations. Five fetuses recovered spo...
journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294837
更新日期:1992-01-01 00:00:00