Adenosine inhibits basal forebrain cholinergic and noncholinergic neurons in vitro.

abstract：:The participation of excitatory neurotransmitter systems in the basal ganglia in the initiation and propagation of limbic seizures induced by pilocarpine has been investigated in the rat. Limbic seizures (electrographic and motor) occur in rats receiving bilateral microinjections into the entopeduncular nucleus of 12....

journal_title：Neuroscience

authors： Patel S,De Sarro GB,Meldrum BS

更新日期：1988-12-01 00:00:00

abstract：:Using structural magnetic resonance imaging in a clinical scanner at 3.0T, we describe results showing that following 12weeks on a diet of 2% cholesterol, rabbits experience a significant increase in the volume of the third ventricle compared to rabbits on a diet of 0% cholesterol. Using time-of-flight magnetic resona...

journal_title：Neuroscience

authors： Schreurs BG,Smith-Bell CA,Lemieux SK

更新日期：2013-12-19 00:00:00

abstract：:Enkephalins are peptides which have pharmacological properties similar to those of morphine. Guinea pigs were immunized with a leucine-enkephalin/thyroglobulin conjugate. Immunofluorescence histochemistry with antiserum revealed a widely distributed system of axons and their terminals in the nervous system of the rat....

journal_title：Neuroscience

authors： Elde R,Hökfelt T,Johansson O,Terenius L

更新日期：1976-08-01 00:00:00

abstract：:Oxytocin (OT) levels in plasma increase during sexual response and are significantly lower in patients with depression. A drug for the treatment of sexual dysfunction, sildenafil, enhances the electrically evoked release of OT from the posterior pituitary. In this study, we showed that sildenafil had an antidepressant...

journal_title：Neuroscience

authors： Matsushita H,Matsuzaki M,Han XJ,Nishiki TI,Ohmori I,Michiue H,Matsui H,Tomizawa K

更新日期：2012-01-03 00:00:00

abstract：:Previous studies have shown that acoustic trauma can disrupt the firing of place cells in the hippocampus and also inhibit hippocampal neurogenesis, suggesting that such trauma might impair spatial memory. In this study, we investigated performance in the alternating T maze and Morris water maze of rats exposed to aco...

journal_title：Neuroscience

authors： Zheng Y,Hamilton E,Begum S,Smith PF,Darlington CL

更新日期：2011-07-14 00:00:00

abstract：:The host response to neural injury, which can include axonal sprouting and synaptic reorganization is likely to be under tight genetic regulatory control at the level of the genome and may be implicated in epileptogenesis. Despite its importance, however, the molecular basis of synaptic reorganization is unclear. We h...

journal_title：Neuroscience

authors： Yang J,Houk B,Shah J,Hauser KF,Luo Y,Smith G,Schauwecker E,Barnes GN

更新日期：2005-01-01 00:00:00

abstract：:Immunoreactive nerve cell bodies and fibres in the intestine have been examined using three antibody preparations raised against 5-hydroxytryptamine. Cross reactivity studies indicate that the substance localized was an hydroxylated indoleamine. In the guinea-pig small intestine, nerve cell bodies were located in the ...

journal_title：Neuroscience

authors： Costa M,Furness JB,Cuello AC,Verhofstad AA,Steinbusch HW,Elde RP

更新日期：1982-02-01 00:00:00

abstract：:The histopathological sequelae of parenteral administration of kainic acid were investigated in immature rats (3-35 days of age). The brains were fixed 1-14 days after the administration of kainate and the damage evaluated by means of argyrophylic (Fink-Heimer, Gallyas or Nauta-Gygax) and Nissl stains. In animals of l...

journal_title：Neuroscience

authors： Nitecka L,Tremblay E,Charton G,Bouillot JP,Berger ML,Ben-Ari Y

更新日期：1984-12-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of dopamine on the function of synapses formed by cholinergic neurons derived from the rat retina. We used an experimental culture system in which rat striated muscle cells served as postsynaptic targets for cholinergic neurons of the retina. This culture system ...

journal_title：Neuroscience

authors： Yeh HH,Battelle BA,Puro DG

更新日期：1984-11-01 00:00:00

abstract：:The expression of voltage-gated sodium channels is regulated at multiple levels, and in this study we addressed the potential for alternative splicing of the Na(v)1.2, Na(v)1.3, Na(v)1.6 and Na(v)1.7 mRNAs. We isolated novel mRNA isoforms of Na(v)1.2 and Na(v)1.3 from adult mouse and rat dorsal root ganglia (DRG), Na(...

journal_title：Neuroscience

authors： Kerr NC,Holmes FE,Wynick D

更新日期：2008-08-26 00:00:00

abstract：:Mammalian nociceptors have been classified into subclasses based on differential neurotrophin sensitivity and binding of the plant isolectin B4 (IB4). Most of the nerve growth factor-responsive IB4-negative (IB4 (-)) nociceptors contain neuropeptides such as substance P and calcitonin gene-related peptide, whereas the...

journal_title：Neuroscience

authors： Matsuka Y,Edmonds B,Mitrirattanakul S,Schweizer FE,Spigelman I

更新日期：2007-01-19 00:00:00

abstract：:FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR. Its association with mental disorders has been identified, but its function in disease development is largely unknown. Long-term potentiation (LTP) is a functiona...

journal_title：Neuroscience

authors： Qiu B,Xu Y,Wang J,Liu M,Dou L,Deng R,Wang C,Williams KE,Stewart RB,Xie Z,Ren W,Zhao Z,Shou W,Liang T,Yong W

更新日期：2019-03-15 00:00:00

abstract：:Dominant and subordinate males respond differently to the stress of social interaction. After an hour of social interaction, subordinate male Anolis carolinensis have elevated serotonergic activity in hippocampus, but dominant males do not. In other species, and using other stressors, the activation of hippocampal ser...

journal_title：Neuroscience

authors： Summers CH,Summers TR,Moore MC,Korzan WJ,Woodley SK,Ronan PJ,Höglund E,Watt MJ,Greenberg N

更新日期：2003-01-01 00:00:00

abstract：:The pontine projection of the flocculus and adjacent ventral paraflocculus was investigated with antegrade and retrograde axonal tracer techniques. Injections of horseradish peroxidase into the floccular complex revealed subsets of labeled neurons in the nucleus reticularis tegmenti pontis, the nucleus raphe pontis an...

journal_title：Neuroscience

authors： Gerrits NM,Epema AH,Voogd J

更新日期：1984-03-01 00:00:00

abstract：:Neonatal inhibition of brain estrogen formation in male rats by administration of the aromatase inhibitor, 1,4,6-androstatriene-3,17-dione (ATD), permanently changes aspects of their mating behavior and partner preference in adulthood. The medial preoptic area receives chemosensory inputs via a sexually dimorphic vome...

journal_title：Neuroscience

authors： Bakker J,Baum MJ,Slob AK

更新日期：1996-09-01 00:00:00

abstract：:Limb amputation in urodele amphibia is followed by formation of a blastema, which subsequently develops into a complete limb with normal pattern of innervation. In this study, we investigated the effects of axolotl limb blastemas on axonal growth in gels of collagen and extracellular matrix (matrigel). When peripheral...

journal_title：Neuroscience

authors： Tonge DA,Leclere PG

更新日期：2000-01-01 00:00:00

abstract：:By employing both in vivo and in vitro labeling techniques, opiate receptors were labeled with tritiated diprenorphine in the monkey brain and localized by light microscopic autoradiography. Both methods of labeling gave similar results, allowing a description of discrete areas having opiate binding sites. High concen...

journal_title：Neuroscience

authors： Wamsley JK,Zarbin MA,Young WS 3rd,Kuhar MJ

更新日期：1982-03-01 00:00:00

abstract：:Sigma receptor (sigmaR), known as a unique nonopiate, nonphencyclidine brain receptor, can bind diverse classes of psychotropic drugs, neurosteroids and other synthetic compounds, such as (+)pentazocine, etc. Two types of sigmaRs have been identified: sigmaR1 and sigmaR2. In this work, we examined the expression of si...

journal_title：Neuroscience

authors： Liu LL,Wang L,Zhong YM,Yang XL

更新日期：2010-06-02 00:00:00

abstract：:The lurcher mutation induces Purkinje cell degeneration in heterozygous mice, and neonatal death in homozygous animals. Using the D6Mit16 Simple Sequence Length Polymorphic marker in F2 hybrids between AKR +/+ mice and B6+/Lc mice, homozygous lurcher fetuses and newborns as well as heterozygous and normal littermates ...

journal_title：Neuroscience

authors： Resibois A,Cuvelier L,Goffinet AM

更新日期：1997-09-01 00:00:00

abstract：:Wobbler mice display forelimb weakness, altered paw positioning, reduced running speed, muscle atrophy and motor neuron loss; co-treatment with glycosaminoglycans and insulin-like growth factor-I counteracts the progression of the disease. Reportedly, treatment with glycosaminoglycans or insulin-like growth factor-I s...

journal_title：Neuroscience

authors： Vergani L,Losa M,Lesma E,Di Giulio AM,Torsello A,Müller EE,Gorio A

更新日期：1999-01-01 00:00:00

abstract：:In vivo voltammetry was used to study the effects of basolateral amygdala dopamine depletion on stress-induced dopamine release in the nucleus accumbens and medial prefrontal cortex. Male Long-Evans rats received bilateral microinjections of 6-hydroxydopamine or vehicle into the basolateral amygdala. Changes in dopami...

journal_title：Neuroscience

authors： Stevenson CW,Sullivan RM,Gratton A

更新日期：2003-01-01 00:00:00

abstract：:Further cytochemical studies on the ultrastructural localization of 5'-nucleotidase in the rat retina have revealed activity to be associated with the complex synapses formed by the rod spherules of the receptors and the bipolar and horizontal cell processes. Activity was also seen on the axolemma of receptor fibers. ...

journal_title：Neuroscience

authors： Kreutzberg GW,Hussain ST

更新日期：1984-04-01 00:00:00

abstract：:The anxiolytic diazepam selectively inhibits psychological stress-induced autonomic and behavioral responses without causing noticeable suppression of other central performances. This pharmacological property of diazepam led us to the idea that neurons that exhibit diazepam-sensitive, psychological stress-induced acti...

journal_title：Neuroscience

authors： Lkhagvasuren B,Oka T,Nakamura Y,Hayashi H,Sudo N,Nakamura K

更新日期：2014-07-11 00:00:00

abstract：:Golgi, Nissl, Bielschowsky and cholinesterase techniques have been used to analyze the optic tectum of the weakly electric teleost fish Eigenmannia virescens and Apteronotus leptorhynchus. Six layers are readily distinguished: a fairly thick stratum marginale, a narrow stratum opticum and stratum fibrosum et griseum s...

journal_title：Neuroscience

authors： Sas E,Maler L

更新日期：1986-05-01 00:00:00

abstract：:Throughout his scientific career, Tom Jessell pioneered the spinal cord as a model system to study the molecular programs of neural specification, axon guidance, and connection specificity. His contributions to these fields and more broadly to that of developmental neuroscience will continue to inspire and define many...

journal_title：Neuroscience

authors： Balaskas N,Ng D,Zampieri N

更新日期：2020-12-01 00:00:00

abstract：:A significant number of postmenopausal women report increased anxiety and vulnerability to stress, which has been linked to decreased secretion of ovarian steroids. Communication between the serotonin system and the corticotropin releasing factor (CRF) system determines stress sensitivity or resilience. This study exa...

journal_title：Neuroscience

authors： Sanchez RL,Reddy AP,Bethea CL

更新日期：2010-12-15 00:00:00

abstract：:Many epidemiological studies support the notion that people who drink alcohol also smoke cigarettes and vice versa thereby suggesting a possible functional interaction between these two most widely used psychoactive substances. We have earlier demonstrated that direct intracerebellar (ICB) microinfusion of nicotine do...

journal_title：Neuroscience

authors： Taslim N,Al-Rejaie S,Saeed Dar M

更新日期：2008-11-11 00:00:00

abstract：:Prenatal exposure to high-fat diet (HFD) might predispose offspring to develop metabolic and mental disorders later in life. Insight into the molecular and behavioral consequences of maternal HFD on offspring is sparse but may involve both neuroinflammation and a dysregulated neuroendocrine stress axis. Thus, the aim ...

journal_title：Neuroscience

authors： Winther G,Elfving B,Müller HK,Lund S,Wegener G

更新日期：2018-09-15 00:00:00

abstract：:Experimental animal studies have demonstrated a number of receptor localizations on specific cortical afferents and neurons. The present study of human posterior cingulate cortex evaluates the laminar distributions of particular receptors and their likely association with components of the neuropil. Coverslip autoradi...

journal_title：Neuroscience

authors： Vogt BA,Plager MD,Crino PB,Bird ED

更新日期：1990-01-01 00:00:00

abstract：:Nickel (Ni(2+)) is a toxic metal that affects the function of several ionic channels. In the N-methyl-d-aspartate (NMDA) subtype of glutamate receptor (NR), it causes activity enhancement of the channels containing the NR2B subunit and voltage-independent inhibition of those containing NR2A. Thus, it may represent a f...

journal_title：Neuroscience

authors： Gavazzo P,Tedesco M,Chiappalone M,Zanardi I,Marchetti C

更新日期：2011-03-17 00:00:00