Abstract:
:Integration of bovine leukaemia virus DNA was investigated at all stages of infection in cattle. We report here the detection of integrated proviral DNA in the majority of antibody positive animals without lymphocytosis. In all but one case virus was integrated at a number of different sites. Hybridization analysis failed to detect proviral sequences in animals shown to be BLV antibody-negative by the Agar Gel Immunodiffusion assay. The pattern of integration in leukocytes from animals with persistent lymphocytosis was similar to that in sero-positive animals without lymphocytosis in that multiple sites of integration were evident. As reported by others only one or a few sites of integration were detected in tumours from enzootic bovine leukosis animals. Tumours from different sites in individual animals were either monoclonal or oligoclonal.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Coulston J,Daniel RC,Lavin MFdoi
10.1007/BF01314319keywords:
subject
Has Abstractpub_date
1991-01-01 00:00:00pages
13-23issue
1-2eissn
0304-8608issn
1432-8798journal_volume
119pub_type
杂志文章abstract::Two non-virogenic Vero cell lines persistently infected with the arenavirus Junin (JUNV), named V3 and V7, were characterized with respect to their resistance to superinfection with homologous and antigenically related viruses. Both lines were refractory to JUNV multiplication and partially resistant to other arenavir...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-003-0227-1
更新日期:2004-03-01 00:00:00
abstract::The thymidine kinase (TK) of herpesviruses, in contrast to cellular TKs, phosphorylates a variety of substrates including antiherpetic nucleoside analogues. This study reports the identification and DNA sequence of the simian varicella virus (SVV) TK gene. A 32P-labeled varicella zoster virus (VZV) TK DNA probe hybrid...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718587
更新日期:1996-01-01 00:00:00
abstract::Bovine lactoferrin (LF) and ribavirin (Rbv) were tested as antiviral agents against Seoul type hantavirus (SR-11 strain) in vitro. Hantaviral foci number in Vero E6 cells infected with SR-11 was reduced with LF treatment by 5 days post infection to obtain a 50% effective dose (ED50) of 2500 microg/ml, while pretreatme...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050070077
更新日期:2000-01-01 00:00:00
abstract::The mechanism of cell death induced by feline immunodeficiency virus (FIV) infection was investigated in an interleukin 2(IL-2)-dependent T-lymphoblastoid cell line (MYA-1). DNA extracted from FIV-infected MYA-1 cells showed a ladder of nucleosomal DNA, indicating that the cytopathic effect (CPE) observed in these cel...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309772
更新日期:1994-01-01 00:00:00
abstract::A collection of 148 adenovirus strains of subgenus C collected in Argentina, Chile, and Uruguay were studied by restriction enzyme analysis of genomic DNA with endonucleases BamHI, BglII, BstEII, EcoRI, HindIII, KpnI, and SmaI. Only strains corresponding to serotypes 1, 2, and 5 were identified representing both alrea...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309841
更新日期:1993-01-01 00:00:00
abstract::The genomes of all replication-competent retroviruses contain cis-acting elements that regulate gene expression. However, the identities of many of these elements remain to be characterized. Inserting sequences into the 3' untranslated region of a replication-competent spleen necrosis virus (SNV) vector disrupted its ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050486
更新日期:1999-01-01 00:00:00
abstract::The numbers of the carbohydrate side chains have been analyzed on a series of subtype 7 hemagglutinins of influenza A virus. The procedure employed involves growth of the virus in the presence of the trimming inhibitor N-methyl-1-desoxynojirimycin followed by controlled removal of the resulting mannose-rich oligosacch...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314433
更新日期:1987-01-01 00:00:00
abstract::Pseudocowpox is a zoonosis caused by pseudocowpox virus (PCPV), which mainly affects cows but can be an occupational disease of humans. The aim of the study was to validate a quantitative polymerase chain reaction (qPCR) assay for the detection of PCPV. The assay was able to detect up to 1000 copies of PCPV per µL in ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04872-4
更新日期:2021-01-01 00:00:00
abstract::Phylogenetic relationships of novel Vietnamese strains of feline immunodeficiency virus (FIV) were analysed. One Vietnamese strain was found to cluster with subtype D, which was previously known only in Japan, while the other seven strains were placed with members of subtype C. Calculation of the relative numbers of m...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0954-8
更新日期:2003-04-01 00:00:00
abstract::The present study confirms that herpesviruses (LF) previously isolated from testes and buffy coat cells of male turkeys with semen abnormalities establish a latent infection in testicular cells. These experiments also present the first evidence that these herpesviruses are harbored latently in cells of spinal ganglia....
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311163
更新日期:1984-01-01 00:00:00
abstract::Tryptic peptide analyses were performed on the major internal structural proteins of type D retroviruses isolated originally from subhuman primate species (MPMV, SMRV, LV) and from permanent human cell lines (HeLaV, HEp-2V, PMFV). The p25 peptide maps of MPMV, LV, PMFV and HEp-2V were very similar but showed a strikin...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309302
更新日期:1984-01-01 00:00:00
abstract::Human adenoviruses (Ad) 5 and 7 multiplied poorly in guinea-pig cell cultures as compared to HeLa cells. Ad 7 had a modified polypeptide composition with a major 43K component. This change persisted for up to 4 passages in HeLa cells. Ad 5 was not changed by passage in guinea-pig cells. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01320631
更新日期:1980-01-01 00:00:00
abstract::The structure of the scrapie agent remains unknown. However, scrapie infectivity tends to co-sediment with an infection specific fraction of the glycoprotein PrP (PrPSc) under conditions which solubilise the normal form of this protein (PrPc); accordingly, PrP has been proposed as a candidate component of the agent. T...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718399
更新日期:1996-01-01 00:00:00
abstract::Optimal conditions of radial haemolysis in gel (HIG) with Chikungunya (Chik) and Japanese encephalitis (JE) viruses were developed and compared with those of rubella virus. Sheep erythrocytes were found preferable for HIG with Chik and JE viruses, unlike rubella virus, where goose erythrocytes gave best results. Roost...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01320619
更新日期:1980-01-01 00:00:00
abstract::The in vitro cytopathology and the neurovirulence to inbred mice demonstrated by five variants originally derived from one laboratory strain (Miyama) of type 1 herpes simplex virus (HSV-1) were studied comparatively. Three of the variants are syncytial [+GC (LPV), +GC (SPV), +GC (81)] and two are non-syncytial [-GCr a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317369
更新日期:1986-01-01 00:00:00
abstract::The stools of slaughtered pigs were screened for hepatitis E virus (HEV). HEV RNA was detected in 7.3% of the samples. HEV strains were characterized as genotype 3 subtype c, a cluster previously not described in Italy. These findings provide evidence that slaughterhouse workers may be exposed to HEV infection. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0544-0
更新日期:2010-01-01 00:00:00
abstract::Mutations were introduced by recombinant DNA techniques into 9 genes of an infectious molecular clone of human immunodeficiency virus type 1. The 24 mutants generated were characterized biochemically and biologically by transfection and infection experiments. None of the mutants which have mutations in gag (p17, p24, ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310491
更新日期:1991-01-01 00:00:00
abstract::Infection of soybean by the plant cytorhabdovirus soybean blotchy mosaic virus (SbBMV) results in significant yield losses in the temperate, lower-lying soybean production regions of South Africa. A 277 bp portion of the RNA-dependent RNA polymerase gene of 66 SbBMV isolates from different: hosts, geographical locatio...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-3722-0
更新日期:2018-05-01 00:00:00
abstract::Human cytomegalovirus disappeared from cultures continuously exposed to interferon. When interferon was removed, high titers of virus reappeared. Cytomegalovirus was thus able to persist in potentially infectious form in cells protected by interferon. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309276
更新日期:1983-01-01 00:00:00
abstract::The diagnosis of cytomegalovirus retinitis (CMV-R) is difficult and usually based on clinical criteria or invasive diagnostic procedures. The purpose of this study was to investigate a possible association between CMV-R and specific anti-CMV antibodies in tears. Paired tear and serum samples were obtained from 96 indi...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0813-0
更新日期:2006-12-01 00:00:00
abstract::Eighty-six varicella-zoster virus (VZV) strains of clades 1, 3 and 5, isolated from varicella and zoster patients in Germany, were analyzed by sequencing the glycoprotein E gene. Four novel non-synonymous and 10 novel synonymous mutations were detected. Of these, two synonymous (C513T, C885T) and two non-synonymous mu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0864-0
更新日期:2011-03-01 00:00:00
abstract::Human peripheral blood mononuclear cells (PBMC) can be infected in vitro with sera of hepatitis C virus (HCV)-infected patients. We have treated pools of PBMC with dextran sulfate MW 8,000, before infection with various HCV(+) sera. When the cells were treated with dextran sulfate 10-3 M, HCV RNA was no longer detecta...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050293
更新日期:1998-01-01 00:00:00
abstract::The entry of enveloped viruses into host cells requires the fusion of viral and cell membranes. These membrane fusion reactions are mediated by virus-encoded glycoproteins. In the case of avian metapneumovirus (aMPV), the fusion (F) protein alone can mediate virus entry and induce syncytium formation in vitro. To inve...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2524-x
更新日期:2015-10-01 00:00:00
abstract::To understand the mode of persistent infection of Seoul virus in rodents, we examined the distribution of the virus genome and antibody production in infected rats. When 1-day-old rats were inoculated with the KI-83-262 strain, the S segment of viral genome was detected in sera, clots, lungs and kidneys from 3 to 184 ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718634
更新日期:1996-01-01 00:00:00
abstract::A non-neutralizing monoclonal antibody (YO-60) against human rotavirus was found to be directed to VP2 (90,000-dalton protein), one of the two major components of the inner capsid. The reactivity patterns of the YO-60 antibody were very similar, though not identical, to those of subgroup II-specific YO-5 monoclonal an...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310550
更新日期:1986-01-01 00:00:00
abstract::RNA viruses are classified by their genome polarity and replication strategies. Nucleotide composition and codon usage differ among virus groups, for instance positive-sense RNA (+ssRNA) viruses have higher GC-content than the other RNA virus groups. Codon usage of +ssRNA viruses is closer to humans showing significan...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-3930-7
更新日期:2018-10-01 00:00:00
abstract::Serologic and virologic prevalence of infection with different swine influenza virus (SIV) subtypes was investigated using swine sera, nasal swabs and lung samples that had been submitted for a diagnosis to the Minnesota Veterinary Diagnostic Laboratory. A total of 111,418 pig sera were tested for SIV antibody between...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0788-4
更新日期:2002-06-01 00:00:00
abstract::Little is known about the bacteriophage proteins expressed immediately after infection of the host cell. Most of these early proteins are probably involved in bacteriophage-host interactions redirecting the bacterial metabolism to phage production. Interaction analysis of the first 16 phiKMV gene products (gp) identif...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-0967-4
更新日期:2007-01-01 00:00:00
abstract::Both H9N2 subtype avian influenza and 2009 pandemic H1N1 viruses (pH1N1) can infect humans and pigs, which provides the opportunity for virus reassortment, leading to the genesis of new strains with potential pandemic risk. In this study, we generated six reassortant H9 viruses in the background of three pH1N1 strains...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2009-3
更新日期:2014-07-01 00:00:00
abstract::Strains of an influenza H10N4 virus have been isolated during an outbreak of a respiratory disease in mink on the south-east coast of Sweden. This was the first example of a disease in mammals caused by the H10 subtype. We compared the A/mink/Sweden/84 strain with two recent avian H10N4 isolates, one from fowl and ano...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01318353
更新日期:1990-01-01 00:00:00