Abstract:
:In yeasts, several sensing systems localized to the plasma membrane which transduce information regarding the availability and quality of nitrogen and carbon sources and work in parallel with the intracellular nutrient-sensing systems, regulate the expression and activity of proteins involved in nutrient uptake and utilization. The aim of this work was to establish whether the cellular signals triggered by amino acids modify the expression of the UGA4 gene which encodes the delta-aminolevulinic (ALA) and gamma-aminobutyric (GABA) acids permease. In the present paper, we demonstrate that extracellular amino acids regulate UGA4 expression and that this effect seems to be mediated by the amino acid sensor complex SPS (SSY1, PTR3, SSY5).
journal_name
Arch Microbioljournal_title
Archives of microbiologyauthors
Bermudez Moretti M,Perullini AM,Batlle A,Correa Garcia Sdoi
10.1007/s00203-005-0022-3keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
137-40issue
2eissn
0302-8933issn
1432-072Xjournal_volume
184pub_type
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