Gender differences in bipolar disorder: retrospective data from the first 500 STEP-BD participants.

abstract：OBJECTIVES:Hypotheses regarding mood dysregulation in bipolar disorder (BD) have centered on limbic overactivity with relative prefrontal underactivity during mood episodes. Therefore, we hypothesized that adolescents with bipolar depression successfully treated with lamotrigine would show decreases in amygdalar activa...

journal_title：Bipolar disorders

authors： Chang KD,Wagner C,Garrett A,Howe M,Reiss A

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder (BD) is a common and highly disabling disease characterized by substantial cognitive and functional impairment. The exact neurobiological mechanisms underlying the expression of symptoms in this condition remain unknown but there is growing evidence that glutamate might play an important rol...

journal_title：Bipolar disorders

authors： Gigante AD,Bond DJ,Lafer B,Lam RW,Young LT,Yatham LN

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the antimanic efficacy and safety of paliperidone extended-release (ER) tablets in patients with bipolar I disorder. METHODS:This study included a 3-week, double-blind, acute treatment phase (paliperidone ER versus placebo, with quetiapine as control), and a 9-week, double-blind, maintenance pha...

journal_title：Bipolar disorders

authors： Vieta E,Nuamah IF,Lim P,Yuen EC,Palumbo JM,Hough DW,Berwaerts J

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:Up to 75% of patients with bipolar I disorder (BD-I) are overweight or obese. Obesity is associated with an increased liability for mood episodes in patients with established BD-I, but data from early in the illness are lacking. Obesity in the general population is also consistently associated with functiona...

journal_title：Bipolar disorders

authors： Bond DJ,Kunz M,Torres IJ,Lam RW,Yatham LN

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Several lines of evidence suggest that deficits in cognition persist in bipolar patients during periods of euthymia. Working memory impairment has been observed in euthymic bipolar patients and noted to be a significant source of functional deficits in psychiatric disorders. Functional changes associated wit...

journal_title：Bipolar disorders

authors： Adler CM,Holland SK,Schmithorst V,Tuchfarber MJ,Strakowski SM

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:Cognition is a new treatment target to aid functional recovery and enhance quality of life for patients with bipolar disorder. The International Society for Bipolar Disorders (ISBD) Targeting Cognition Task Force aimed to develop consensus-based clinical recommendations on whether, when and how to assess and...

journal_title：Bipolar disorders

authors： Miskowiak KW,Burdick KE,Martinez-Aran A,Bonnin CM,Bowie CR,Carvalho AF,Gallagher P,Lafer B,López-Jaramillo C,Sumiyoshi T,McIntyre RS,Schaffer A,Porter RJ,Purdon S,Torres IJ,Yatham LN,Young AH,Kessing LV,Vieta E

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:We sought to determine whether the risk of relapse in patients with bipolar disorder is higher after discontinuation and restart of lithium treatment as compared to continuous lithium treatment in these same patients. METHODS:We conducted literature searches in the Pubmed, Embase, Cochrane, and PsycINFO dat...

journal_title：Bipolar disorders

authors： de Vries C,van Bergen A,Regeer EJ,Benthem E,Kupka RW,Boks MP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Bipolar disorder is associated with a high frequency of both completed suicides and suicide attempts. The primary aim of this study was to identify clinical predictors of suicide attempts in subjects with bipolar disorder. METHODS:We studied 336 subjects with a diagnosis of bipolar I, bipolar II, or schizoaf...

journal_title：Bipolar disorders

authors： Dalton EJ,Cate-Carter TD,Mundo E,Parikh SV,Kennedy JL

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:Few studies have examined the abnormalities that underlie the neuroanatomy of bipolar disorder in youth. The aim of this study was to evaluate brain regions that are thought to modulate mood utilizing quantitative analyses of thin-slice magnetic resonance imaging (MRI) scans of adolescents with bipolar disor...

journal_title：Bipolar disorders

authors： DelBello MP,Zimmerman ME,Mills NP,Getz GE,Strakowski SM

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Patients with remitted bipolar disorder (BD) have persistent impairments in neuropsychological function, particularly in the domains of executive control and declarative memory [Br J Psychiatry 180 (2002) 293]. If these were the phenotypic expression of genetic vulnerability to BD, then healthy subjects with ...

journal_title：Bipolar disorders

authors： Ferrier IN,Chowdhury R,Thompson JM,Watson S,Young AH

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:Cognitive dysfunction affects a significant proportion of people with bipolar disorder (BD), but the cause, trajectory and correlates of such dysfunction remains unclear. Increased understanding of these factors is required to progress treatment development for this symptom dimension. METHODS:This paper pro...

journal_title：Bipolar disorders

authors： Van Rheenen TE,Lewandowski KE,Bauer IE,Kapczinski F,Miskowiak K,Burdick KE,Balanzá-Martínez V

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Many morphometric magnetic resonance imaging (MRI) studies that have investigated the presence of gray matter (GM) volume abnormalities associated with the diagnosis of bipolar disorder (BD) have reported conflicting findings. None of these studies has compared patients with recent-onset psychotic BD with as...

journal_title：Bipolar disorders

authors： de Azevedo-Marques Périco C,Duran FL,Zanetti MV,Santos LC,Murray RM,Scazufca M,Menezes PR,Busatto GF,Schaufelberger MS

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Studies into social cognition in psychiatric disorders have recently been expanded to address the question of whether or not theory of mind (ToM), i.e., the ability to represent ones own and others mental states, is impaired in bipolar affective disorder (BPD). Results have been mixed so far, mainly due to p...

journal_title：Bipolar disorders

authors： Wolf F,Brüne M,Assion HJ

更新日期：2010-09-01 00:00:00

abstract：:It has become increasingly appreciated that the long-term treatment of complex neuropsychiatric disorders like bipolar disorder (BD) involves the strategic regulation of signaling pathways and gene expression in critical neuronal circuits. Accumulating evidence from our laboratories and others has identified the famil...

journal_title：Bipolar disorders

authors： Chen G,Masana MI,Manji HK

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:An emerging body of evidence supports a role for dysfunctional purinergic neurotransmission in mood disorders. Adenosine agonists have been shown to have properties similar to those of dopamine antagonists; there is a well-characterized interaction between adenosine and dopamine receptors in the ventral stria...

journal_title：Bipolar disorders

authors： Weiser M,Burshtein S,Gershon AA,Marian G,Vlad N,Grecu IG,Tocari E,Tiugan A,Hotineanu M,Davis JM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Studies have suggested that episode polarity at illness onset in bipolar disorder may be predictive of some aspects of lifetime clinical characteristics. We here examine this possibility in a large, well-characterized sample of patients with bipolar I disorder. METHODS:We assessed polarity at onset in patie...

journal_title：Bipolar disorders

authors： Forty L,Jones L,Jones I,Smith DJ,Caesar S,Fraser C,Gordon-Smith K,Hyde S,Craddock N

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To assess aggression, irritability and hostility in children at risk for bipolar disorder (BP). METHODS:Using the parent and the child versions of the Children's Hostility Inventory (CHI), we assessed aggression, hostility, and irritability in 300 offspring aged 6-18 years old of BP parents and 169 children...

journal_title：Bipolar disorders

authors： Farchione TR,Birmaher B,Axelson D,Kalas C,Monk K,Ehmann M,Iyengar S,Kupfer D,Brent D

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset. METHOD:Data ...

journal_title：Bipolar disorders

authors： Bauer M,Glenn T,Alda M,Andreassen OA,Ardau R,Bellivier F,Berk M,Bjella TD,Bossini L,Del Zompo M,Dodd S,Fagiolini A,Frye MA,Gonzalez-Pinto A,Henry C,Kapczinski F,Kliwicki S,König B,Kunz M,Lafer B,Lopez-Jaramillo C

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost-effectiveness, mediating mechanisms, and moderators of effects. METHODS:Systematic searches of the MEDLINE and PSYCHLIT databases yielded 19 randomized controlled trials of individual family an...

journal_title：Bipolar disorders

authors： Miklowitz DJ,Scott J

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder (BD) is a psychiatric disorder with high morbidity and mortality that cannot be distinguished from major depressive disorder (MDD) until the first manic episode. A biomarker able to differentiate BD and MDD could help clinicians avoid risks of treating BD with antidepressants without mood st...

journal_title：Bipolar disorders

authors： Lan MJ,Chhetry BT,Oquendo MA,Sublette ME,Sullivan G,Mann JJ,Parsey RV

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to inform ongoing attempts to identify clinically meaningful subcategories of auditory verbal hallucination (AVH), and to evaluate evidence that might pertain to the suitability of current psychological interventions for people with bipolar disorder (BD) who experience psycho...

journal_title：Bipolar disorders

authors： Smith LM,Johns LC,Mitchell R

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Suicide is a leading cause of death in the USA. Although factors elevating long-term risk for suicide are known and include bipolar disorder, signs of imminent suicide risk are difficult to study and not well specified. Acute risk determinations must be made to determine the appropriate level of care to safe...

journal_title：Bipolar disorders

authors： Chesin M,Stanley B

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:To evaluate frequency and severity of separation anxiety (SA) symptoms, as well as frequency of DSM-IV diagnosis of childhood separation anxiety disorder (CSAD) and adult separation anxiety disorder (ASAD), in a group of patients with bipolar disorder (BD) when compared with patients with panic disorder (PD)...

journal_title：Bipolar disorders

authors： Pini S,Abelli M,Mauri M,Muti M,Iazzetta P,Banti S,Cassano GB

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:To examine the nature of executive deficits in euthymic patients with bipolar disorder (BD). METHODS:Fifteen euthymic BD patients and 13 controls were administered a battery of executive tasks including verbal fluency, Stroop, Theory of Mind (ToM) tests and selected subtests from the Cambridge Neuropsycholo...

journal_title：Bipolar disorders

authors： Olley AL,Malhi GS,Bachelor J,Cahill CM,Mitchell PB,Berk M

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Recent theories regarding the neuropathology of bipolar disorder suggest that both neurodevelopmental and neurodegenerative processes may play a role. While magnetic resonance imaging has provided significant insight into the structural, functional, and connectivity abnormalities associated with bipolar disor...

journal_title：Bipolar disorders

authors： Schneider MR,DelBello MP,McNamara RK,Strakowski SM,Adler CM

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:To compare the clinical features and course of major depressive episodes (MDEs) occurring in subjects with bipolar I disorder (BD-I), bipolar II disorder (BD-II), and major depressive disorder (MDD). METHODS:Data were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions (2001-2002)...

journal_title：Bipolar disorders

authors： Moreno C,Hasin DS,Arango C,Oquendo MA,Vieta E,Liu S,Grant BF,Blanco C

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Cognitive remediation therapy (CRT) may benefit people with bipolar disorder type I and II for whom cognitive impairment is a major contributor to disability. Extensive research has demonstrated CRT to improve cognition and psychosocial functioning in people with different diagnoses, but randomised trials of...

journal_title：Bipolar disorders

authors： Strawbridge R,Tsapekos D,Hodsoll J,Mantingh T,Yalin N,McCrone P,Boadu J,Macritchie K,Cella M,Reeder C,Fish J,Wykes T,Young AH

更新日期：2020-06-24 00:00:00

abstract：OBJECTIVES:We investigated the neuroprotective effects of lithium in an experimental neurodegeneration model gated to kainate (KA) receptor activation. METHODS:The hippocampus from KA-treated mice and hippocampal cell cultures were used to evaluate the pathways regulated by chronic lithium pretreatment in both in vivo...

journal_title：Bipolar disorders

authors： Crespo-Biel N,Camins A,Canudas AM,Pallàs M

更新日期：2010-06-01 00:00:00

abstract：:The Diagnostic Guidelines Task Force of the International Society for Bipolar Disorders (ISBD) presents in this document and this special issue a summary of the current nosological status of bipolar illness, a discussion of possible revisions to current DSM-IV and ICD-10 definitions, an examination of the relevant lit...

journal_title：Bipolar disorders

authors： Ghaemi SN,Bauer M,Cassidy F,Malhi GS,Mitchell P,Phelps J,Vieta E,Youngstrom E,ISBD Diagnostic Guidelines Task Force.

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:Significant debate exists on whether early onset bipolar disorder is mistakenly attributed to attention deficit hyperactivity disorder (ADHD) or conduct disorder (CD), or whether ADHD and CD are frequently misdiagnosed as mania. We review the literature on the extent to which these disorders can be reliably ...

journal_title：Bipolar disorders

authors： Kim EY,Miklowitz DJ

更新日期：2002-08-01 00:00:00