Cortical thickness differences between bipolar depression and major depressive disorder.

abstract：OBJECTIVES:The question of whether there is a continuum or a dichotomy among patients with schizophrenia (SZ) and bipolar disorders (BD) has not been clearly resolved and remains a challenge. Thus, the identification of specific biomarkers of these disorders might be helpful. The present study investigated the volume o...

journal_title：Bipolar disorders

authors： Tréhout M,Leroux E,Delcroix N,Dollfus S

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:  Inflammation and other immune processes are increasingly linked to psychiatric diseases. Antigenic triggers specific to bipolar disorder are not yet defined. We tested whether antibodies to bovine milk caseins were associated with bipolar disorder, and whether patients recognized different epitopes of the ...

journal_title：Bipolar disorders

authors： Severance EG,Dupont D,Dickerson FB,Stallings CR,Origoni AE,Krivogorsky B,Yang S,Haasnoot W,Yolken RH

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:The mood-stabilizing drug valproic acid (VPA) exerts a neurotrophic effect on the human neuroblastoma cell line, SH-SY5Y. We aimed to establish whether other mood-stabilizing drugs have a similar action and which signalling pathways mediate this process. METHODS:We analysed the effects of the mood stabilize...

journal_title：Bipolar disorders

authors： Di Daniel E,Mudge AW,Maycox PR

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:Previous studies have indicated abnormalities in response flexibility in pediatric bipolar disorder (BD). Dysfunction in response flexibility may contribute to the pattern of behavioral and emotional dysregulation that is characteristic of BD, since depressed and manic patients respond inflexibly to emotiona...

journal_title：Bipolar disorders

authors： Nelson EE,Vinton DT,Berghorst L,Towbin KE,Hommer RE,Dickstein DP,Rich BA,Brotman MA,Pine DS,Leibenluft E

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:As part of a cost-effectiveness analysis for Department of Veterans Affairs Cooperative Studies Program #430, 'Reducing the Efficacy-Effectiveness Gap in Bipolar Disorder,' we conducted a time and motion study to quantify the time psychiatric clinical nurse specialist (CNS) care managers spent providing care...

journal_title：Bipolar disorders

authors： Glick HA,Kinosian B,McBride L,Williford WO,Bauer MS,CSP #430 Study Team.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:Lithium overdose may result in encephalopathy and electroencephalographic abnormalities. Three poisoning patterns have been identified based on the ingested dose, previous treatment duration and renal function. Whether the severity of lithium-induced encephalopathy depends on the poisoning pattern has not be...

journal_title：Bipolar disorders

authors： Hanak AS,Malissin I,Poupon J,Risède P,Chevillard L,Mégarbane B

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:While the pathophysiology of bipolar disorder (BD) remains to be elucidated, postmortem and neuroimaging studies have suggested that abnormalities in the dorsolateral prefrontal cortex (DLPFC) are implicated. We compared the levels of specific brain chemicals of interest measured with proton magnetic resonan...

journal_title：Bipolar disorders

authors： Frey BN,Stanley JA,Nery FG,Monkul ES,Nicoletti MA,Chen HH,Hatch JP,Caetano SC,Ortiz O,Kapczinski F,Soares JC

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:To investigate whether first admission with mania is associated with the occurrence of death in the family or with major stressful life events and to explore whether the associations change with age. METHODS:Case register study with linkage of the Danish Psychiatric Central Research Register, including data...

journal_title：Bipolar disorders

authors： Kessing LV,Agerbo E,Mortensen PB

更新日期：2004-04-01 00:00:00

abstract：:The widely held clinical view of 'antidepressants' as highly effective and specific for the treatment of all types of depressive disorders is exaggerated. This sobering conclusion is supported by recent findings from the NIMH-sponsored STEP-BD and STAR*D projects. Antidepressants have limited short-term efficacy in un...

journal_title：Bipolar disorders

authors： Ghaemi SN

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Many morphometric magnetic resonance imaging (MRI) studies that have investigated the presence of gray matter (GM) volume abnormalities associated with the diagnosis of bipolar disorder (BD) have reported conflicting findings. None of these studies has compared patients with recent-onset psychotic BD with as...

journal_title：Bipolar disorders

authors： de Azevedo-Marques Périco C,Duran FL,Zanetti MV,Santos LC,Murray RM,Scazufca M,Menezes PR,Busatto GF,Schaufelberger MS

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:To compare the dimensional psychopathology in offspring of parents with bipolar disorder (BP) with offspring of community control parents as assessed by the Child Behavior Checklist (CBCL). METHODS:Offspring of parents with BP, who were healthy or had non-BP disorders (any psychiatric disorder other than BP...

journal_title：Bipolar disorders

authors： Diler RS,Birmaher B,Axelson D,Obreja M,Monk K,Hickey MB,Goldstein B,Goldstein T,Sakolsky D,Iyengar S,Brent D,Kupfer D

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Bipolar disorders are associated with high rates of suicide attempts (SAs) and completions. Several factors have been reported to be associated with suicide in persons with bipolar disorder, but most studies to date have been retrospective and have not utilized multivariate statistics to account for the redu...

journal_title：Bipolar disorders

authors： Marangell LB,Bauer MS,Dennehy EB,Wisniewski SR,Allen MH,Miklowitz DJ,Oquendo MA,Frank E,Perlis RH,Martinez JM,Fagiolini A,Otto MW,Chessick CA,Zboyan HA,Miyahara S,Sachs G,Thase ME

更新日期：2006-10-01 00:00:00

abstract：:Data from the imaging literature have led to suggestions that permanent structural brain changes may be associated with bipolar disorder. Individuals diagnosed with bipolar disorder display deficits on a range of neuropsychological tasks in both the acute and euthymic phases of illness, and correlations between experi...

journal_title：Bipolar disorders

authors： Savitz J,Solms M,Ramesar R

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:The enzyme glycogen synthase kinase-3β (GSK3β) is involved in the mechanisms of action of lithium and may play a role in relation to affective states in bipolar disorder. The objectives of the present study were to compare the activity of GSK-3β (measured as levels of phosphorylated GSK-3β [p-GSK-3β]) betwee...

journal_title：Bipolar disorders

authors： Jacoby AS,Munkholm K,Vinberg M,Joaquim HG,Talib LL,Gattaz WF,Kessing LV

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Patients with remitted bipolar disorder (BD) have persistent impairments in neuropsychological function, particularly in the domains of executive control and declarative memory [Br J Psychiatry 180 (2002) 293]. If these were the phenotypic expression of genetic vulnerability to BD, then healthy subjects with ...

journal_title：Bipolar disorders

authors： Ferrier IN,Chowdhury R,Thompson JM,Watson S,Young AH

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:This study examined health care resource utilization and direct health care costs among patients diagnosed with bipolar I disorder in a privately insured population. METHODS:Health care claims data for 2883 patients with a primary diagnosis of bipolar disorder were compared over a 1-year period (1997) with c...

journal_title：Bipolar disorders

authors： Bryant-Comstock L,Stender M,Devercelli G

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset. METHOD:Data ...

journal_title：Bipolar disorders

authors： Bauer M,Glenn T,Alda M,Andreassen OA,Ardau R,Bellivier F,Berk M,Bjella TD,Bossini L,Del Zompo M,Dodd S,Fagiolini A,Frye MA,Gonzalez-Pinto A,Henry C,Kapczinski F,Kliwicki S,König B,Kunz M,Lafer B,Lopez-Jaramillo C

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Drug repurposing is an increasingly promising idea in many fields of medicine. We systematically used Danish nation-wide population-based registers to investigate whether continued use of non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs), low-dose aspirin, high-dose aspirin, statins, allopurinol, and...

journal_title：Bipolar disorders

authors： Kessing LV,Rytgaard HC,Gerds TA,Berk M,Ekstrøm CT,Andersen PK

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The present study evaluated inhaled loxapine for the acute treatment of agitation in patients with bipolar I disorder. METHODS:A Phase 3, randomized, double blind, placebo-controlled, parallel group inpatient study was performed at 17 psychiatric research facilities. Agitated patients (N=314) with bipolar I ...

journal_title：Bipolar disorders

authors： Kwentus J,Riesenberg RA,Marandi M,Manning RA,Allen MH,Fishman RS,Spyker DA,Kehne JH,Cassella JV

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:Bipolar affective disorder (BPAD) is clinically and genetically heterogeneous and the affected phenotype is poorly defined, hampering studies of its genetic basis. Studies of specific, familial, clinical indicators of BPAD may be useful for identifying heritable forms. Homogeneous forms of the disease may be...

journal_title：Bipolar disorders

authors： Etain B,Roy I,Henry C,Rousseva A,Schürhoff F,Leboyer M,Bellivier F

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Emotion regulation difficulties precipitate and exacerbate acute mood symptoms in individuals with bipolar disorder (BD), and contribute to suicidal behavior. However, few studies have examined regional brain responses in explicit emotion regulation during acute BD mood states, or hopelessness, a major suici...

journal_title：Bipolar disorders

authors： Sankar A,Purves K,Colic L,Cox Lippard ET,Millard H,Fan S,Spencer L,Wang F,Pittman B,Constable RT,Gross JJ,Blumberg HP

更新日期：2020-06-10 00:00:00

abstract：OBJECTIVES:Caregivers of people with bipolar disorder often have depression and health problems. This study aimed to evaluate the sustained effects of a 12-15 week psychoeducational intervention on the health and mental health of caregivers of persons with bipolar disorder. We also evaluated the effects of the interven...

journal_title：Bipolar disorders

authors： Perlick DA,Jackson C,Grier S,Huntington B,Aronson A,Luo X,Miklowitz DJ

更新日期：2018-11-01 00:00:00

abstract：:Bipolar disorder is a complex condition that includes symptoms of mania, depression, and often anxiety. Diagnosing and treating bipolar depression is challenging, with the disorder often being diagnosed as unipolar depression. In addition, comorbid anxiety can be a significant detractor to successful outcomes, increas...

journal_title：Bipolar disorders

authors： McIntyre R,Katzman M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:A high prevalence rate of bipolar disorder (BP) comorbid with alcohol dependence (AD) (BP+AD) in Western patients with BP has been reported, but whether this is true for Han Chinese with BP is uncertain. We explored the prevalence of BP+AD in a Han Chinese population with BP, and investigated the effect of a...

journal_title：Bipolar disorders

authors： Chang YH,Lee SY,Wang TY,Chen SL,Tzeng NS,Chen PS,Lee IH,Chen KC,Huang SY,Yang YK,Ko HC,Lu RB

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Hypotheses regarding mood dysregulation in bipolar disorder (BD) have centered on limbic overactivity with relative prefrontal underactivity during mood episodes. Therefore, we hypothesized that adolescents with bipolar depression successfully treated with lamotrigine would show decreases in amygdalar activa...

journal_title：Bipolar disorders

authors： Chang KD,Wagner C,Garrett A,Howe M,Reiss A

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:Laboratory monitoring of patients using lithium is important to prevent harm and to increase effectiveness. The aim of this study is to determine compliance with the guidelines for laboratory monitoring of patients treated with lithium overall and within subgroups. METHODS:Patients having at least one lithi...

journal_title：Bipolar disorders

authors： Nederlof M,Egberts TC,van Londen L,de Rotte MC,Souverein PC,Herings RM,Heerdink ER

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Diffusion-weighted magnetic resonance imaging (MRI) has shown increased sensitivity in detecting brain white matter disease compared to traditional T2-weighted MRI. Diffusion-weighted imaging (DWI) can quantitatively assess the microstructural integrity of white matter using the average apparent diffusion coe...

journal_title：Bipolar disorders

authors： Regenold WT,D'Agostino CA,Ramesh N,Hasnain M,Roys S,Gullapalli RP

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:The increased standardized mortality ratio (SMR) from cardiovascular disease (CVD) in women with bipolar disorder (BD), relative to men with BD and individuals of both sexes in the general population, provides the impetus to identify factors that contribute to the differential association of obesity with BD i...

journal_title：Bipolar disorders

authors： Baskaran A,Cha DS,Powell AM,Jalil D,McIntyre RS

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Suicide is a multicausal human behavior, with devastating and immensely distressing consequences. Its prevalence is estimated to be 20-30 times greater in patients with bipolar disorders than in the general population. The burden of suicide and its high prevalence in bipolar disorders make it imperative th...

journal_title：Bipolar disorders

authors： Malhi GS,Outhred T,Das P,Morris G,Hamilton A,Mannie Z

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Studies have suggested that episode polarity at illness onset in bipolar disorder may be predictive of some aspects of lifetime clinical characteristics. We here examine this possibility in a large, well-characterized sample of patients with bipolar I disorder. METHODS:We assessed polarity at onset in patie...

journal_title：Bipolar disorders

authors： Forty L,Jones L,Jones I,Smith DJ,Caesar S,Fraser C,Gordon-Smith K,Hyde S,Craddock N

更新日期：2009-02-01 00:00:00