Diffusion-weighted magnetic resonance imaging of white matter in bipolar disorder: a pilot study.

abstract：OBJECTIVES:Diagnosis and management of bipolar disorder (BD) are limited by the absence of available biomarkers. Allostatic load (AL) represents the strain that stress, including the effects of acute phases and inter-episode chronic mood instability, exerts on interconnected biological systems. This study aimed to oper...

journal_title：Bipolar disorders

authors： Dargél AA,Volant S,Brietzke E,Etain B,Olié E,Azorin JM,Gard S,Bellivier F,Bougerol T,Kahn JP,Roux P,Aubin V,Courtet P,Leboyer M,Henry C,FACE-BD collaborators.

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:The Bipolar Disorders: Improving Diagnosis, Guidance and Education (BRIDGE)-II-Mix study aimed to estimate the frequency of mixed states in patients with a major depressive episode (MDE) according to different definitions. The present post-hoc analysis evaluated the association between obesity and the presen...

journal_title：Bipolar disorders

authors： Petri E,Bacci O,Barbuti M,Pacchiarotti I,Azorin JM,Angst J,Bowden CL,Mosolov S,Vieta E,Young AH,Perugi G,BRIDGE-II-Mix Study Group.

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Experts have debated the ability of patients with bipolar illness to consent to research participation when manic. We compared 25 euthymic bipolar and 26 manic bipolar patients in their understanding of three hypothetical studies of varying complexity. METHODS:Hypothetical studies were presented as written ...

journal_title：Bipolar disorders

authors： Misra S,Socherman R,Park BS,Hauser P,Ganzini L

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Treatment-emergent mania (TEM) represents a common phenomenon inconsistently reported across primary studies, warranting further assessment. METHODS:A systematic review and meta-analysis following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) and Meta-Analysis of Observation...

journal_title：Bipolar disorders

authors： Fornaro M,Anastasia A,Novello S,Fusco A,Solmi M,Monaco F,Veronese N,De Berardis D,de Bartolomeis A

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The study was designed to test an audit-based quality improvement programme (QIP) addressing lithium prescribing and monitoring in UK mental health services. METHODS:A baseline clinical audit was conducted against the following standards: (i) measurement of renal and thyroid function before initiating treat...

journal_title：Bipolar disorders

authors： Paton C,Adroer R,Barnes TR

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:Lithium overdose may result in encephalopathy and electroencephalographic abnormalities. Three poisoning patterns have been identified based on the ingested dose, previous treatment duration and renal function. Whether the severity of lithium-induced encephalopathy depends on the poisoning pattern has not be...

journal_title：Bipolar disorders

authors： Hanak AS,Malissin I,Poupon J,Risède P,Chevillard L,Mégarbane B

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Impaired verbal declarative memory has been proposed as a trait marker for adult bipolar disorder. However, similar impairments in juvenile-onset bipolar disorder have not been yet documented. Here, we assessed declarative memory in a large sample of clinically well-characterized children with bipolar disord...

journal_title：Bipolar disorders

authors： Glahn DC,Bearden CE,Caetano S,Fonseca M,Najt P,Hunter K,Pliszka SR,Olvera RL,Soares JC

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether treatment with lithium in patients with mania or bipolar disorder is associated with a decreased rate of subsequent dementia. METHODS:Linkage of register data on prescribed lithium in all patients discharged from psychiatric health care service with a diagnosis of mania or bipolar diso...

journal_title：Bipolar disorders

authors： Kessing LV,Forman JL,Andersen PK

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To compare the quality of life (QOL) of patients having dual diagnosis of bipolar affective disorder and substance dependence with those having either diagnosis alone and with healthy controls. METHODS:Cross-sectional assessment of the four groups of subjects was made. Euthymic bipolar patients and those su...

journal_title：Bipolar disorders

authors： Singh J,Mattoo SK,Sharan P,Basu D

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:We conducted a study of clinical presentation and family history in patients responsive to either of two commonly used mood stabilizers, lithium and lamotrigine. METHODS:The sample included 164 subjects from 21 families of bipolar probands, 14 responders to lithium and seven to lamotrigine. Diagnostic inform...

journal_title：Bipolar disorders

authors： Passmore MJ,Garnham J,Duffy A,MacDougall M,Munro A,Slaney C,Teehan A,Alda M

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:The mood-stabilizing drug valproic acid (VPA) exerts a neurotrophic effect on the human neuroblastoma cell line, SH-SY5Y. We aimed to establish whether other mood-stabilizing drugs have a similar action and which signalling pathways mediate this process. METHODS:We analysed the effects of the mood stabilize...

journal_title：Bipolar disorders

authors： Di Daniel E,Mudge AW,Maycox PR

更新日期：2005-02-01 00:00:00

abstract：:Lithium, the major drug used to treat manic depressive illness, robustly protects cultured rat brain neurons from glutamate excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptors. The lithium neuroprotection against glutamate excitotoxiciy is long-lasting, requires long-term pretreatment and occurs at therap...

journal_title：Bipolar disorders

authors： Chuang DM,Chen RW,Chalecka-Franaszek E,Ren M,Hashimoto R,Senatorov V,Kanai H,Hough C,Hiroi T,Leeds P

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Bipolar affective disorder (BPAD) is clinically and genetically heterogeneous and the affected phenotype is poorly defined, hampering studies of its genetic basis. Studies of specific, familial, clinical indicators of BPAD may be useful for identifying heritable forms. Homogeneous forms of the disease may be...

journal_title：Bipolar disorders

authors： Etain B,Roy I,Henry C,Rousseva A,Schürhoff F,Leboyer M,Bellivier F

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The serotonin hypothesis plays a critical role in the etiology of bipolar disorder (BD). Although many studies have demonstrated reciprocal relationships between serotonin metabolism and immune-inflammatory pathways that occur in depression, studies linking serotonergic function and cytokines are still limit...

journal_title：Bipolar disorders

authors： Hsu JW,Lirng JF,Wang SJ,Lin CL,Yang KC,Liao MH,Chou YH

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Depression research historically uses both self- and clinician ratings of symptoms with significant and substantial correlations. It is often assumed that manic patients lack insight and cannot accurately report their symptoms. This delayed the development of self-rating scales for mania, but several scales ...

journal_title：Bipolar disorders

authors： Meyer TD,Crist N,La Rosa N,Ye B,Soares JC,Bauer IE

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Objective physiological indices independently characterizing affective and schizophreniform psychoses would contribute to our understanding of the nature of their relationships. Magnetoencephalography (MEG)-based metrics of altered structural/functional asymmetry in the superior temporal gyrus have previousl...

journal_title：Bipolar disorders

authors： Reite M,Teale P,Rojas DC,Reite E,Asherin R,Hernandez O

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Approximate entropy (ApEn) measures regularity in time series data, while traditional linear statistics measure variability. Using self-reported mood data from patients with bipolar disorder, this preliminary study addressed whether ApEn could distinguish (i) the 60 days prior to the start of a manic or depr...

journal_title：Bipolar disorders

authors： Glenn T,Whybrow PC,Rasgon N,Grof P,Alda M,Baethge C,Bauer M

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Outcomes research in bipolar disorders, because of complex clinical variation over-time, offers demanding research design and statistical challenges. Longitudinal studies involving relatively large samples, with outcome measures obtained repeatedly over-time, are required. In this report, statistical methods...

journal_title：Bipolar disorders

authors： Hennen J

更新日期：2003-06-01 00:00:00

abstract：:Calcium channel antagonists (CCAs) have many clinical applications, including their possible use in the treatment of bipolar disorder. Two justifications for this last application are some overlap in physiological activities of CCAs with those of lithium, and a possible association between bipolar disorder and calcium...

journal_title：Bipolar disorders

authors： Levy NA,Janicak PG

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To examine gender differences in a large sample of patients with bipolar illness. METHODS:Exploratory analysis of baseline data from the first 500 patients in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), a multi-center NIMH project. Participants are allowed to have medical and...

journal_title：Bipolar disorders

authors： Baldassano CF,Marangell LB,Gyulai L,Ghaemi SN,Joffe H,Kim DR,Sagduyu K,Truman CJ,Wisniewski SR,Sachs GS,Cohen LS

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:To investigate neurochemical abnormalities in the left and right ventrolateral prefrontal cortex (VLPFC) and anterior cingulate cortex (ACC) of youth at risk for bipolar disorder using proton magnetic resonance spectroscopy before and after their first mood episode. METHODS:Children and adolescents offsprin...

journal_title：Bipolar disorders

authors： Nery FG,Weber WA,Blom TJ,Welge J,Patino LR,Strawn JR,Chu WJ,Adler CM,Komoroski RA,Strakowski SM,DelBello MP

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:Cognitive dysfunction affects a significant proportion of people with bipolar disorder (BD), but the cause, trajectory and correlates of such dysfunction remains unclear. Increased understanding of these factors is required to progress treatment development for this symptom dimension. METHODS:This paper pro...

journal_title：Bipolar disorders

authors： Van Rheenen TE,Lewandowski KE,Bauer IE,Kapczinski F,Miskowiak K,Burdick KE,Balanzá-Martínez V

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:To evaluate frequency and severity of separation anxiety (SA) symptoms, as well as frequency of DSM-IV diagnosis of childhood separation anxiety disorder (CSAD) and adult separation anxiety disorder (ASAD), in a group of patients with bipolar disorder (BD) when compared with patients with panic disorder (PD)...

journal_title：Bipolar disorders

authors： Pini S,Abelli M,Mauri M,Muti M,Iazzetta P,Banti S,Cassano GB

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The present study evaluated inhaled loxapine for the acute treatment of agitation in patients with bipolar I disorder. METHODS:A Phase 3, randomized, double blind, placebo-controlled, parallel group inpatient study was performed at 17 psychiatric research facilities. Agitated patients (N=314) with bipolar I ...

journal_title：Bipolar disorders

authors： Kwentus J,Riesenberg RA,Marandi M,Manning RA,Allen MH,Fishman RS,Spyker DA,Kehne JH,Cassella JV

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder (BD) is a common and highly disabling disease characterized by substantial cognitive and functional impairment. The exact neurobiological mechanisms underlying the expression of symptoms in this condition remain unknown but there is growing evidence that glutamate might play an important rol...

journal_title：Bipolar disorders

authors： Gigante AD,Bond DJ,Lafer B,Lam RW,Young LT,Yatham LN

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Patients experiencing an acute mood episode of bipolar disorder are impaired on cognitive tests of executive functioning when compared with healthy subjects. However, it is unclear to what extent executive dysfunction exists (i) during syndromal remission, when mood symptoms are attenuated, and (ii) during t...

journal_title：Bipolar disorders

authors： Fleck DE,Shear PK,Madore M,Strakowski SM

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Although it is well established that euthymic patients with bipolar disorder can have cognitive impairment, substantial heterogeneity exists and little is known about the extent and severity of impairment within the bipolar II disorder subtype. Therefore, the main aim of this study was to analyze cognitive v...

journal_title：Bipolar disorders

authors： Solé B,Jiménez E,Torrent C,Del Mar Bonnin C,Torres I,Reinares M,Priego Á,Salamero M,Colom F,Varo C,Vieta E,Martínez-Arán A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:The use of olanzapine (OLZ) in the prevention of postpartum psychosis (PP) and mood episodes in women with bipolar disorder was investigated in a naturalistic, prospective study. METHODS:Eleven women received OLZ alone or in combination with an antidepressant or mood stabilizer, and 14 women received either...

journal_title：Bipolar disorders

authors： Sharma V,Smith A,Mazmanian D

更新日期：2006-08-01 00:00:00

abstract：:With great interest, we have read the recent paper by Keramatian and colleagues entitled "Grey Matter Abnormalities in First Episode Mania: A Systematic Review and Meta-analysis of Voxel-Based Morphometry Studies" in Bipolar Disorders1 . The authors systematically reviewed 15 voxel-based morphometry (VBM) studies and ...

journal_title：Bipolar disorders

authors： Sheng L,Ma H,Dai Z,Yao L,Hu J

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVES:The enzyme glycogen synthase kinase-3β (GSK3β) is involved in the mechanisms of action of lithium and may play a role in relation to affective states in bipolar disorder. The objectives of the present study were to compare the activity of GSK-3β (measured as levels of phosphorylated GSK-3β [p-GSK-3β]) betwee...

journal_title：Bipolar disorders

authors： Jacoby AS,Munkholm K,Vinberg M,Joaquim HG,Talib LL,Gattaz WF,Kessing LV

更新日期：2016-06-01 00:00:00