Phenotypic spectra of bipolar disorder in responders to lithium versus lamotrigine.

abstract：OBJECTIVE:Although second-generation antipsychotics (SGAs) are widely used in treating schizophrenia and bipolar disorder, their effects on dyslipidemia, glucose intolerance, metabolic syndrome (MetS), and coronary heart disease (CHD) risk are less well documented for bipolar disorder. We compared bipolar disorder and ...

journal_title：Bipolar disorders

authors： Correll CU,Frederickson AM,Kane JM,Manu P

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:  Inflammation and other immune processes are increasingly linked to psychiatric diseases. Antigenic triggers specific to bipolar disorder are not yet defined. We tested whether antibodies to bovine milk caseins were associated with bipolar disorder, and whether patients recognized different epitopes of the ...

journal_title：Bipolar disorders

authors： Severance EG,Dupont D,Dickerson FB,Stallings CR,Origoni AE,Krivogorsky B,Yang S,Haasnoot W,Yolken RH

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Despite effective pharmacological treatments for bipolar disorder, we still lack a comprehensive pathophysiological model of the illness. Recent neurobiological research has implicated a number of key brain regions and neuronal components in the behavioural and cognitive manifestations of bipolar disorder. Do...

journal_title：Bipolar disorders

authors： Cousins DA,Butts K,Young AH

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Approximate entropy (ApEn) measures regularity in time series data, while traditional linear statistics measure variability. Using self-reported mood data from patients with bipolar disorder, this preliminary study addressed whether ApEn could distinguish (i) the 60 days prior to the start of a manic or depr...

journal_title：Bipolar disorders

authors： Glenn T,Whybrow PC,Rasgon N,Grof P,Alda M,Baethge C,Bauer M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Patients with mood disorders may benefit from psychosocial interventions through changes in brain networks underlying emotion processing. In this study, we used functional magnetic resonance imaging (fMRI) to investigate treatment-related changes in emotion processing networks in youth at familial high risk ...

journal_title：Bipolar disorders

authors： Garrett AS,Chang KD,Singh MK,Armstrong CC,Walshaw PD,Miklowitz DJ

更新日期：2021-01-12 00:00:00

abstract：OBJECTIVE:To report a case report of a geriatric patient with a 5-year history of gabapentin use for enhanced bipolar control, who was tapered off of gabapentin over 1 week. The patient displayed unique withdrawal symptoms after the taper of gabapentin. METHODS:The patient is an 81-year-old white female with a life-lo...

journal_title：Bipolar disorders

authors： Tran KT,Hranicky D,Lark T,Jacob Nj

更新日期：2005-06-01 00:00:00

abstract：:Bipolar disorders (BPD) are major, life-long psychiatric illnesses found in 2-5% of the population. Prognosis for BPD was once considered relatively favorable, but contemporary findings suggest that disability and poor outcomes are prevalent, despite major therapeutic advances. Syndromal recovery from acute episodes o...

journal_title：Bipolar disorders

authors： Huxley N,Baldessarini RJ

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to determine the role of genetic variations within the zinc finger protein 804A (ZNF804A) gene, a candidate for a psychosis risk-conferring gene, in the development of schizophrenia (SZ) and bipolar disorder (BP) in the Korean population. METHODS:A total of 921 patients with SZ, bipo...

journal_title：Bipolar disorders

authors： Baek JH,Ha K,Kim Y,Yang SY,Cho EY,Choi Y,Ryu S,Lee YS,Park T,Hong KS

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:An emerging body of evidence supports a role for dysfunctional purinergic neurotransmission in mood disorders. Adenosine agonists have been shown to have properties similar to those of dopamine antagonists; there is a well-characterized interaction between adenosine and dopamine receptors in the ventral stria...

journal_title：Bipolar disorders

authors： Weiser M,Burshtein S,Gershon AA,Marian G,Vlad N,Grecu IG,Tocari E,Tiugan A,Hotineanu M,Davis JM

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Individuals with bipolar disorder (BD) have trait-like deficits in attention and working memory (WM). A fundamental dissociation for most verbal WM theories involves the separation of sensory-perceptual encoding, reliant upon attention, from the maintenance of this information in WM proper. The present study...

journal_title：Bipolar disorders

authors： McKenna BS,Sutherland AN,Legenkaya AP,Eyler LT

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:Although olfactory abnormalities are well established in schizophrenia, considerably less work has examined olfactory performance in other neuropsychiatric conditions. In the current study, we examined odor identification, odor discrimination, detection threshold, and odor hedonic processing performance in i...

journal_title：Bipolar disorders

authors： Kamath V,Paksarian D,Cui L,Moberg PJ,Turetsky BI,Merikangas KR

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state. METHODS:To examine this issue, we administered the California Verbal Learning Test a...

journal_title：Bipolar disorders

authors： Fleck DE,Shear PK,Zimmerman ME,Getz GE,Corey KB,Jak A,Lebowitz BK,Strakowski SM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:Outcomes research in bipolar disorders, because of complex clinical variation over-time, offers demanding research design and statistical challenges. Longitudinal studies involving relatively large samples, with outcome measures obtained repeatedly over-time, are required. In this report, statistical methods...

journal_title：Bipolar disorders

authors： Hennen J

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:Mismatch negativity (MMN) and its magnetic counterpart (MMNm) are thought to reflect an automatic process that detects a difference between an incoming stimulus and the sensory memory trace of preceding stimuli. In patients with schizophrenia, an attenuation of the MMN/MMNm amplitude has been repeatedly repo...

journal_title：Bipolar disorders

authors： Shimano S,Onitsuka T,Oribe N,Maekawa T,Tsuchimoto R,Hirano S,Ueno T,Hirano Y,Miura T,Kanba S

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:While the pathophysiology of bipolar disorder (BD) remains to be elucidated, postmortem and neuroimaging studies have suggested that abnormalities in the dorsolateral prefrontal cortex (DLPFC) are implicated. We compared the levels of specific brain chemicals of interest measured with proton magnetic resonan...

journal_title：Bipolar disorders

authors： Frey BN,Stanley JA,Nery FG,Monkul ES,Nicoletti MA,Chen HH,Hatch JP,Caetano SC,Ortiz O,Kapczinski F,Soares JC

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study has been to examine differences in the laterality of pain in patients with migraine and comorbid unipolar depressive (UP) and bipolar II (BP II) disorders. METHODS:Semi-structured interviews of 102 patients with major affective disorders were conducted, using DSM-IV criteria...

journal_title：Bipolar disorders

authors： Fasmer OB,Oedegaard KJ

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder (BD) has been associated with impairment in affective processing during depressive and manic states; however, there are limited data as to whether this population exhibits such difficulty during stable periods. We examined the pattern of affective processing in stable BD patients and compare...

journal_title：Bipolar disorders

authors： Gopin CB,Burdick KE,Derosse P,Goldberg TE,Malhotra AK

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Experts have debated the ability of patients with bipolar illness to consent to research participation when manic. We compared 25 euthymic bipolar and 26 manic bipolar patients in their understanding of three hypothetical studies of varying complexity. METHODS:Hypothetical studies were presented as written ...

journal_title：Bipolar disorders

authors： Misra S,Socherman R,Park BS,Hauser P,Ganzini L

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Affective psychoses and bipolar disorders have been neglected in the development of early intervention strategies. This paper aims to gather current knowledge on the early phase of bipolar disorders in order to define new targets for early intervention. METHODS:Literature review based on the main computerize...

journal_title：Bipolar disorders

authors： Conus P,Ward J,Hallam KT,Lucas N,Macneil C,McGorry PD,Berk M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:As part of a cost-effectiveness analysis for Department of Veterans Affairs Cooperative Studies Program #430, 'Reducing the Efficacy-Effectiveness Gap in Bipolar Disorder,' we conducted a time and motion study to quantify the time psychiatric clinical nurse specialist (CNS) care managers spent providing care...

journal_title：Bipolar disorders

authors： Glick HA,Kinosian B,McBride L,Williford WO,Bauer MS,CSP #430 Study Team.

更新日期：2004-12-01 00:00:00

abstract：:Calcium channel antagonists (CCAs) have many clinical applications, including their possible use in the treatment of bipolar disorder. Two justifications for this last application are some overlap in physiological activities of CCAs with those of lithium, and a possible association between bipolar disorder and calcium...

journal_title：Bipolar disorders

authors： Levy NA,Janicak PG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Depression research historically uses both self- and clinician ratings of symptoms with significant and substantial correlations. It is often assumed that manic patients lack insight and cannot accurately report their symptoms. This delayed the development of self-rating scales for mania, but several scales ...

journal_title：Bipolar disorders

authors： Meyer TD,Crist N,La Rosa N,Ye B,Soares JC,Bauer IE

更新日期：2020-09-01 00:00:00

abstract：:Bipolar disorder is a complex condition that includes symptoms of mania, depression, and often anxiety. Diagnosing and treating bipolar depression is challenging, with the disorder often being diagnosed as unipolar depression. In addition, comorbid anxiety can be a significant detractor to successful outcomes, increas...

journal_title：Bipolar disorders

authors： McIntyre R,Katzman M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:Previous studies have indicated abnormalities in response flexibility in pediatric bipolar disorder (BD). Dysfunction in response flexibility may contribute to the pattern of behavioral and emotional dysregulation that is characteristic of BD, since depressed and manic patients respond inflexibly to emotiona...

journal_title：Bipolar disorders

authors： Nelson EE,Vinton DT,Berghorst L,Towbin KE,Hommer RE,Dickstein DP,Rich BA,Brotman MA,Pine DS,Leibenluft E

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:The study was designed to test an audit-based quality improvement programme (QIP) addressing lithium prescribing and monitoring in UK mental health services. METHODS:A baseline clinical audit was conducted against the following standards: (i) measurement of renal and thyroid function before initiating treat...

journal_title：Bipolar disorders

authors： Paton C,Adroer R,Barnes TR

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:Despite known metabolic effects of second-generation antipsychotics (SGAs) on children and adolescents, comparative effects in youth with different diagnoses remain underreported. We compared differences in metabolic changes three months after starting treatment with SGAs in youth with bipolar disorder and w...

journal_title：Bipolar disorders

authors： Moreno C,Merchán-Naranjo J,Alvarez M,Baeza I,Alda JA,Martínez-Cantarero C,Parellada M,Sánchez B,de la Serna E,Giráldez M,Arango C

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to inform ongoing attempts to identify clinically meaningful subcategories of auditory verbal hallucination (AVH), and to evaluate evidence that might pertain to the suitability of current psychological interventions for people with bipolar disorder (BD) who experience psycho...

journal_title：Bipolar disorders

authors： Smith LM,Johns LC,Mitchell R

更新日期：2017-09-01 00:00:00

abstract：:It has become increasingly appreciated that the long-term treatment of complex neuropsychiatric disorders like bipolar disorder (BD) involves the strategic regulation of signaling pathways and gene expression in critical neuronal circuits. Accumulating evidence from our laboratories and others has identified the famil...

journal_title：Bipolar disorders

authors： Chen G,Masana MI,Manji HK

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Neurocognitive deficits are prevalent, persistent, and implicated as mediators of functional impairment in adults with bipolar disorder. Notwithstanding progress in the development of pharmacological treatments for various phases of bipolar disorder, no available treatment has been proven to be reliably effi...

journal_title：Bipolar disorders

authors： McIntyre RS,Soczynska JK,Woldeyohannes HO,Miranda A,Vaccarino A,Macqueen G,Lewis GF,Kennedy SH

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To examine the feasibility of collecting course of illness data from patients with bipolar I and II disorder, using weekly text-messaged mood ratings, and to examine the time trajectory of symptom ratings based on this method of self-report. METHODS:A total of 62 patients with bipolar I (n = 47) or II (n = ...

journal_title：Bipolar disorders

authors： Bopp JM,Miklowitz DJ,Goodwin GM,Stevens W,Rendell JM,Geddes JR

更新日期：2010-05-01 00:00:00