Verbal memory in mania: effects of clinical state and task requirements.

Abstract:

OBJECTIVES:Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state. METHODS:To examine this issue, we administered the California Verbal Learning Test and symptom-rating scales to inpatients with pure or mixed mania, euthymic outpatients, and healthy comparison subjects. RESULTS:An overall performance difference was identified between groups. Manic and euthymic patients performed more poorly than healthy subjects on recall. However, manic patients performed more poorly than euthymic patients and healthy subjects on recognition. CONCLUSIONS:These results suggest that verbal retrieval deficits are stable vulnerability indicators in bipolar disorder, whereas verbal encoding deficits are manic episode indicators. The known subcortical dysfunction in this disorder may produce stable retrieval deficits while acute mood symptoms attenuate encoding during affective episodes only.

journal_name

Bipolar Disord

journal_title

Bipolar disorders

authors

Fleck DE,Shear PK,Zimmerman ME,Getz GE,Corey KB,Jak A,Lebowitz BK,Strakowski SM

doi

10.1034/j.1399-5618.2003.00055.x

keywords:

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

375-80

issue

5

eissn

1398-5647

issn

1399-5618

pii

055

journal_volume

5

pub_type

杂志文章
  • Missed bipolarity and psychiatric comorbidity in women with postpartum depression.

    abstract:OBJECTIVE:To investigate the diagnostic profile of women referred for postpartum depression. METHODS:Fifty-six women seen consecutively with the referral diagnosis of postpartum depression were administered structured instruments to gather information about their DSM-IV Axis I diagnoses. RESULTS:In terms of frequency...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2008.00606.x

    authors: Sharma V,Khan M,Corpse C,Sharma P

    更新日期:2008-09-01 00:00:00

  • Metabolic effects of second-generation antipsychotics in bipolar youth: comparison with other psychotic and nonpsychotic diagnoses.

    abstract:OBJECTIVES:Despite known metabolic effects of second-generation antipsychotics (SGAs) on children and adolescents, comparative effects in youth with different diagnoses remain underreported. We compared differences in metabolic changes three months after starting treatment with SGAs in youth with bipolar disorder and w...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1399-5618.2010.00797.x

    authors: Moreno C,Merchán-Naranjo J,Alvarez M,Baeza I,Alda JA,Martínez-Cantarero C,Parellada M,Sánchez B,de la Serna E,Giráldez M,Arango C

    更新日期:2010-03-01 00:00:00

  • Ketoconazole in bipolar patients with depressive symptoms: a case series and literature review.

    abstract:BACKGROUND:Data from several studies suggest that medications, such as ketoconazole, which lower cortisol levels, may be effective for major depressive disorder (MDD). As with MDD, the manic, depressive, and mixed phases of bipolar disorder are frequently associated with elevated cortisol levels. The literature on the ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-5618.2001.030103.x

    authors: Brown ES,Bobadilla L,Rush AJ

    更新日期:2001-02-01 00:00:00

  • Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees.

    abstract:OBJECTIVES:We sought to determine if postpartum mood symptoms and depressive episodes exhibit familial aggregation in bipolar I pedigrees. METHODS:A total of 1,130 women were interviewed with the Diagnostic Interview for Genetic Studies as part of the National Institute of Mental Health (NIMH) Genetics Initiative Bipo...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1399-5618.2008.00455.x

    authors: Payne JL,MacKinnon DF,Mondimore FM,McInnis MG,Schweizer B,Zamoiski RB,McMahon FJ,Nurnberger JI Jr,Rice JP,Scheftner W,Coryell W,Berrettini WH,Kelsoe JR,Byerley W,Gershon ES,DePaulo JR Jr,Potash JB

    更新日期:2008-02-01 00:00:00

  • Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons.

    abstract:OBJECTIVES:The mood-stabilizing drug valproic acid (VPA) exerts a neurotrophic effect on the human neuroblastoma cell line, SH-SY5Y. We aimed to establish whether other mood-stabilizing drugs have a similar action and which signalling pathways mediate this process. METHODS:We analysed the effects of the mood stabilize...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2004.00164.x

    authors: Di Daniel E,Mudge AW,Maycox PR

    更新日期:2005-02-01 00:00:00

  • Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: a preliminary report.

    abstract:OBJECTIVE:Patients with remitted bipolar disorder (BD) have persistent impairments in neuropsychological function, particularly in the domains of executive control and declarative memory [Br J Psychiatry 180 (2002) 293]. If these were the phenotypic expression of genetic vulnerability to BD, then healthy subjects with ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2004.00122.x

    authors: Ferrier IN,Chowdhury R,Thompson JM,Watson S,Young AH

    更新日期:2004-08-01 00:00:00

  • Hospitalization risks in the treatment of bipolar disorder: comparison of antipsychotic medications.

    abstract:OBJECTIVES:This study compared the relative risk for hospitalization of patients with bipolar and manic disorders receiving atypical and typical antipsychotics. METHODS:This retrospective study was based on administrative claims data extracted from the PharMetrics database during 1999 through 2003. Comparisons were ma...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2007.00394.x

    authors: Gianfrancesco F,Rajagopalan K,Goldberg JF,Wang RH

    更新日期:2007-05-01 00:00:00

  • Cognitive variability in bipolar II disorder: who is cognitively impaired and who is preserved.

    abstract:OBJECTIVES:Although it is well established that euthymic patients with bipolar disorder can have cognitive impairment, substantial heterogeneity exists and little is known about the extent and severity of impairment within the bipolar II disorder subtype. Therefore, the main aim of this study was to analyze cognitive v...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12385

    authors: Solé B,Jiménez E,Torrent C,Del Mar Bonnin C,Torres I,Reinares M,Priego Á,Salamero M,Colom F,Varo C,Vieta E,Martínez-Arán A

    更新日期:2016-05-01 00:00:00

  • Glycogen synthase kinase-3β in patients with bipolar I disorder: results from a prospective study.

    abstract:OBJECTIVES:The enzyme glycogen synthase kinase-3β (GSK3β) is involved in the mechanisms of action of lithium and may play a role in relation to affective states in bipolar disorder. The objectives of the present study were to compare the activity of GSK-3β (measured as levels of phosphorylated GSK-3β [p-GSK-3β]) betwee...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1111/bdi.12400

    authors: Jacoby AS,Munkholm K,Vinberg M,Joaquim HG,Talib LL,Gattaz WF,Kessing LV

    更新日期:2016-06-01 00:00:00

  • Obesity in patients with major depression is related to bipolarity and mixed features: evidence from the BRIDGE-II-Mix study.

    abstract:OBJECTIVES:The Bipolar Disorders: Improving Diagnosis, Guidance and Education (BRIDGE)-II-Mix study aimed to estimate the frequency of mixed states in patients with a major depressive episode (MDE) according to different definitions. The present post-hoc analysis evaluated the association between obesity and the presen...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1111/bdi.12519

    authors: Petri E,Bacci O,Barbuti M,Pacchiarotti I,Azorin JM,Angst J,Bowden CL,Mosolov S,Vieta E,Young AH,Perugi G,BRIDGE-II-Mix Study Group.

    更新日期:2017-09-01 00:00:00

  • Efficacy of electroconvulsive therapy in bipolar versus unipolar major depression: a meta-analysis.

    abstract:OBJECTIVE:Bipolar major depression differs considerably from unipolar major depression with regard to the efficacy of treatment with antidepressants. In bipolar depression, response to treatment with antidepressants is disappointing. Whether response to electroconvulsive therapy (ECT) differs between bipolar and unipol...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1399-5618.2012.00997.x

    authors: Dierckx B,Heijnen WT,van den Broek WW,Birkenhäger TK

    更新日期:2012-03-01 00:00:00

  • Do positive emotions predict symptomatic change in bipolar disorder?

    abstract:OBJECTIVES:Bipolar disorder is associated with positive emotion disturbance, though it is less clear which specific positive emotions are affected. METHODS:The present study examined differences among distinct positive emotions in recovered bipolar disorder (BD) patients (n = 55) and nonclinical controls (NC) (n = 32)...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2009.00679.x

    authors: Gruber J,Culver JL,Johnson SL,Nam JY,Keller KL,Ketter TA

    更新日期:2009-05-01 00:00:00

  • Olanzapine in the prevention of postpartum psychosis and mood episodes in bipolar disorder.

    abstract:OBJECTIVES:The use of olanzapine (OLZ) in the prevention of postpartum psychosis (PP) and mood episodes in women with bipolar disorder was investigated in a naturalistic, prospective study. METHODS:Eleven women received OLZ alone or in combination with an antidepressant or mood stabilizer, and 14 women received either...

    journal_title:Bipolar disorders

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-5618.2006.00335.x

    authors: Sharma V,Smith A,Mazmanian D

    更新日期:2006-08-01 00:00:00

  • The longitudinal course of bipolar disorder as revealed through weekly text messaging: a feasibility study.

    abstract:OBJECTIVES:To examine the feasibility of collecting course of illness data from patients with bipolar I and II disorder, using weekly text-messaged mood ratings, and to examine the time trajectory of symptom ratings based on this method of self-report. METHODS:A total of 62 patients with bipolar I (n = 47) or II (n = ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2010.00807.x

    authors: Bopp JM,Miklowitz DJ,Goodwin GM,Stevens W,Rendell JM,Geddes JR

    更新日期:2010-05-01 00:00:00

  • Increased oxidative stress after repeated amphetamine exposure: possible relevance as a model of mania.

    abstract:BACKGROUND:Acute mania can be modeled in animals using D-amphetamine (AMPH). Acute AMPH injections are associated with monoamine depletion, loss of neurofilaments and neurite degeneration. However, the precise mechanisms underlying AMPH-induced neurotoxicity are still unclear. Several studies have demonstrated that oxi...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2006.00318.x

    authors: Frey BN,Martins MR,Petronilho FC,Dal-Pizzol F,Quevedo J,Kapczinski F

    更新日期:2006-06-01 00:00:00

  • Monitoring lithium therapy: the impact of a quality improvement programme in the UK.

    abstract:OBJECTIVES:The study was designed to test an audit-based quality improvement programme (QIP) addressing lithium prescribing and monitoring in UK mental health services. METHODS:A baseline clinical audit was conducted against the following standards: (i) measurement of renal and thyroid function before initiating treat...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12128

    authors: Paton C,Adroer R,Barnes TR

    更新日期:2013-12-01 00:00:00

  • Mood spectrum symptoms during a major depressive episode: Differences between 145 patients with bipolar disorder and 155 patients with major depressive disorder. Arguments for a dimensional approach.

    abstract:BACKGROUND:Several studies have challenged the traditional unipolar-bipolar dichotomy in favor of a more dimensional approach. OBJECTIVE:To evaluate the differences in mood spectrum between patients with bipolar disorder (BD) and major depressive disorder (MDD) during a major depressive episode (MDE). METHOD:Study pa...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12855

    authors: Cuomo A,Aguglia A,Aguglia E,Bolognesi S,Goracci A,Maina G,Mineo L,Rucci P,Sillari S,Fagiolini A

    更新日期:2020-06-01 00:00:00

  • Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 years.

    abstract:OBJECTIVES:Bipolar disorders are associated with high rates of suicide attempts (SAs) and completions. Several factors have been reported to be associated with suicide in persons with bipolar disorder, but most studies to date have been retrospective and have not utilized multivariate statistics to account for the redu...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2006.00369.x

    authors: Marangell LB,Bauer MS,Dennehy EB,Wisniewski SR,Allen MH,Miklowitz DJ,Oquendo MA,Frank E,Perlis RH,Martinez JM,Fagiolini A,Otto MW,Chessick CA,Zboyan HA,Miyahara S,Sachs G,Thase ME

    更新日期:2006-10-01 00:00:00

  • Depression in bipolar disorder versus major depressive disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

    abstract:OBJECTIVES:To compare the clinical features and course of major depressive episodes (MDEs) occurring in subjects with bipolar I disorder (BD-I), bipolar II disorder (BD-II), and major depressive disorder (MDD). METHODS:Data were drawn from the National Epidemiologic Survey on Alcohol and Related Conditions (2001-2002)...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2012.01009.x

    authors: Moreno C,Hasin DS,Arango C,Oquendo MA,Vieta E,Liu S,Grant BF,Blanco C

    更新日期:2012-05-01 00:00:00

  • Are existing self-ratings of acute manic symptoms in adults reliable and valid?-A systematic review.

    abstract:BACKGROUND:Depression research historically uses both self- and clinician ratings of symptoms with significant and substantial correlations. It is often assumed that manic patients lack insight and cannot accurately report their symptoms. This delayed the development of self-rating scales for mania, but several scales ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12906

    authors: Meyer TD,Crist N,La Rosa N,Ye B,Soares JC,Bauer IE

    更新日期:2020-09-01 00:00:00

  • The effectiveness of restarted lithium treatment after discontinuation: reviewing the evidence for discontinuation-induced refractoriness.

    abstract:OBJECTIVES:We sought to determine whether the risk of relapse in patients with bipolar disorder is higher after discontinuation and restart of lithium treatment as compared to continuous lithium treatment in these same patients. METHODS:We conducted literature searches in the Pubmed, Embase, Cochrane, and PsycINFO dat...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,评审

    doi:10.1111/bdi.12105

    authors: de Vries C,van Bergen A,Regeer EJ,Benthem E,Kupka RW,Boks MP

    更新日期:2013-09-01 00:00:00

  • No evidence for physical anhedonia as a candidate symptom or an endophenotype in bipolar affective disorder.

    abstract:OBJECTIVES:Bipolar affective disorder (BPAD) is clinically and genetically heterogeneous and the affected phenotype is poorly defined, hampering studies of its genetic basis. Studies of specific, familial, clinical indicators of BPAD may be useful for identifying heritable forms. Homogeneous forms of the disease may be...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2007.00413.x

    authors: Etain B,Roy I,Henry C,Rousseva A,Schürhoff F,Leboyer M,Bellivier F

    更新日期:2007-11-01 00:00:00

  • An investigation of mental imagery in bipolar disorder: Exploring "the mind's eye".

    abstract:OBJECTIVES:Mental imagery abnormalities occur across psychopathologies and are hypothesized to drive emotional difficulties in bipolar disorder (BD). A comprehensive assessment of mental imagery in BD is lacking. We aimed to test whether (i) mental imagery abnormalities (abnormalities in cognitive stages and subjective...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12453

    authors: Di Simplicio M,Renner F,Blackwell SE,Mitchell H,Stratford HJ,Watson P,Myers N,Nobre AC,Lau-Zhu A,Holmes EA

    更新日期:2016-12-01 00:00:00

  • Equally increased risk for metabolic syndrome in patients with bipolar disorder and schizophrenia treated with second-generation antipsychotics.

    abstract:OBJECTIVE:Although second-generation antipsychotics (SGAs) are widely used in treating schizophrenia and bipolar disorder, their effects on dyslipidemia, glucose intolerance, metabolic syndrome (MetS), and coronary heart disease (CHD) risk are less well documented for bipolar disorder. We compared bipolar disorder and ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2008.00625.x

    authors: Correll CU,Frederickson AM,Kane JM,Manu P

    更新日期:2008-11-01 00:00:00

  • Diffusion-weighted magnetic resonance imaging of white matter in bipolar disorder: a pilot study.

    abstract:OBJECTIVE:Diffusion-weighted magnetic resonance imaging (MRI) has shown increased sensitivity in detecting brain white matter disease compared to traditional T2-weighted MRI. Diffusion-weighted imaging (DWI) can quantitatively assess the microstructural integrity of white matter using the average apparent diffusion coe...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2006.00281.x

    authors: Regenold WT,D'Agostino CA,Ramesh N,Hasnain M,Roys S,Gullapalli RP

    更新日期:2006-04-01 00:00:00

  • Kainate-induced toxicity in the hippocampus: potential role of lithium.

    abstract:OBJECTIVES:We investigated the neuroprotective effects of lithium in an experimental neurodegeneration model gated to kainate (KA) receptor activation. METHODS:The hippocampus from KA-treated mice and hippocampal cell cultures were used to evaluate the pathways regulated by chronic lithium pretreatment in both in vivo...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/j.1399-5618.2010.00825.x

    authors: Crespo-Biel N,Camins A,Canudas AM,Pallàs M

    更新日期:2010-06-01 00:00:00

  • Randomized trial comparing caregiver-only family-focused treatment to standard health education on the 6-month outcome of bipolar disorder.

    abstract:OBJECTIVES:Caregivers of people with bipolar disorder often have depression and health problems. This study aimed to evaluate the sustained effects of a 12-15 week psychoeducational intervention on the health and mental health of caregivers of persons with bipolar disorder. We also evaluated the effects of the interven...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/bdi.12621

    authors: Perlick DA,Jackson C,Grier S,Huntington B,Aronson A,Luo X,Miklowitz DJ

    更新日期:2018-11-01 00:00:00

  • Cognitive-behavioral therapy for bipolar disorders in adolescents: a pilot study.

    abstract:OBJECTIVES:To develop a cognitive behavioral intervention for adolescents with bipolar disorders, test its feasibility and preliminary efficacy. METHODS:Based on existing research, a manualized, individually delivered cognitive behavioral intervention was developed and tested with adolescents with bipolar disorders as...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1399-5618.2006.00358.x

    authors: Feeny NC,Danielson CK,Schwartz L,Youngstrom EA,Findling RL

    更新日期:2006-10-01 00:00:00

  • Childhood mania, attention deficit hyperactivity disorder and conduct disorder: a critical review of diagnostic dilemmas.

    abstract:OBJECTIVES:Significant debate exists on whether early onset bipolar disorder is mistakenly attributed to attention deficit hyperactivity disorder (ADHD) or conduct disorder (CD), or whether ADHD and CD are frequently misdiagnosed as mania. We review the literature on the extent to which these disorders can be reliably ...

    journal_title:Bipolar disorders

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-5618.2002.01191.x

    authors: Kim EY,Miklowitz DJ

    更新日期:2002-08-01 00:00:00

  • Differential failure to deactivate the default mode network in unipolar and bipolar depression.

    abstract:OBJECTIVES:Neuroimaging studies have revealed evidence of brain functional abnormalities in bipolar depressive disorder (BDD) and major depressive disorder (MDD). However, few studies to date have compared these two mood disorders directly. METHODS:Matched groups of 26 BDD type I patients, 26 MDD patients and 26 healt...

    journal_title:Bipolar disorders

    pub_type: 杂志文章

    doi:10.1111/bdi.12517

    authors: Rodríguez-Cano E,Alonso-Lana S,Sarró S,Fernández-Corcuera P,Goikolea JM,Vieta E,Maristany T,Salvador R,McKenna PJ,Pomarol-Clotet E

    更新日期:2017-08-01 00:00:00