Abstract:
OBJECTIVES:Mental imagery abnormalities occur across psychopathologies and are hypothesized to drive emotional difficulties in bipolar disorder (BD). A comprehensive assessment of mental imagery in BD is lacking. We aimed to test whether (i) mental imagery abnormalities (abnormalities in cognitive stages and subjective domains) occur in BD relative to non-clinical controls; and (ii) to determine the specificity of any abnormalities in BD relative to depression and anxiety disorders. METHODS:Participants included 54 subjects in the BD group (depressed/euthymic; n=27 in each subgroup), subjects with unipolar depression (n=26), subjects with anxiety disorders (n=25), and non-clinical controls (n=27) matched for age, gender, ethnicity, education, and premorbid IQ. Experimental tasks assessed cognitive (non-emotional) measures of mental imagery (cognitive stages). Questionnaires, experimental tasks, and a phenomenological interview assessed subjective domains including spontaneous imagery use, interpretation bias, and emotional mental imagery. RESULTS:(i) Compared to non-clinical controls, the BD combined group reported a greater impact of intrusive prospective imagery in daily life, more vivid and "real" negative images (prospective imagery task), and higher self-involvement (picture-word task). The BD combined group showed no clear abnormalities in cognitive stages of mental imagery. (ii) When depressed individuals with BD were compared to the depressed or anxious clinical control groups, no significant differences remained-across all groups, imagery differences were associated with affective lability and anxiety. CONCLUSIONS:Compared to non-clinical controls, BD is characterized by abnormalities in aspects of emotional mental imagery within the context of otherwise normal cognitive aspects. When matched for depression and anxiety, these abnormalities are not specific to BD-rather, imagery may reflect a transdiagnostic marker of emotional psychopathology.
journal_name
Bipolar Disordjournal_title
Bipolar disordersauthors
Di Simplicio M,Renner F,Blackwell SE,Mitchell H,Stratford HJ,Watson P,Myers N,Nobre AC,Lau-Zhu A,Holmes EAdoi
10.1111/bdi.12453subject
Has Abstractpub_date
2016-12-01 00:00:00pages
669-683issue
8eissn
1398-5647issn
1399-5618journal_volume
18pub_type
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journal_title:Bipolar disorders
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2012-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2009-12-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 杂志文章,评审
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更新日期:2002-04-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/j.1399-5618.2007.00430.x
更新日期:2007-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1399-5618.2008.00614.x
更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-06-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 杂志文章
doi:10.1111/j.1399-5618.2006.00274.x
更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1399-5618.2007.00576.x
更新日期:2008-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1034/j.1399-5618.2003.00033.x
更新日期:2003-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1034/j.1399-5618.2003.00055.x
更新日期:2003-10-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 杂志文章
doi:10.1111/bdi.12385
更新日期:2016-05-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-03-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2006-10-01 00:00:00
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更新日期:2020-06-24 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2017-09-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2010-05-01 00:00:00
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journal_title:Bipolar disorders
pub_type: 杂志文章
doi:10.1111/j.1399-5618.2008.00654.x
更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-05-01 00:00:00
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doi:10.1111/bdi.12174
更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-06-10 00:00:00
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pub_type: 杂志文章,评审
doi:10.1034/j.1399-5618.2001.030103.x
更新日期:2001-02-01 00:00:00