Calcium channel antagonists for the treatment of bipolar disorder.

abstract：BACKGROUND:There is wide recognition that symptom ratings alone are inadequate to measure outcomes in bipolar disorder (BD), and quality of life (QoL) has been proposed as an important separable construct. Although a literature on QoL in BD exists, there is no disorder-specific measure of QoL in BD. In 2004, we embarke...

journal_title：Bipolar disorders

authors： Michalak EE,Murray G,Collaborative RESearch Team to Study Psychosocial Issues in Bipolar Disorder (CREST.BD).

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:Hypomania in bipolar disorders is characterized by disinhibited, fearless and reward-seeking behavior. This behavioral pattern suggests that early and automatic responding to socio-emotional cues such as facial expressions might be aberrant in hypomania. The present study tested the predictions that particip...

journal_title：Bipolar disorders

authors： Putman P,Saevarsson S,van Honk J

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Significant debate exists on whether early onset bipolar disorder is mistakenly attributed to attention deficit hyperactivity disorder (ADHD) or conduct disorder (CD), or whether ADHD and CD are frequently misdiagnosed as mania. We review the literature on the extent to which these disorders can be reliably ...

journal_title：Bipolar disorders

authors： Kim EY,Miklowitz DJ

更新日期：2002-08-01 00:00:00

abstract：:Lithium, the major drug used to treat manic depressive illness, robustly protects cultured rat brain neurons from glutamate excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptors. The lithium neuroprotection against glutamate excitotoxiciy is long-lasting, requires long-term pretreatment and occurs at therap...

journal_title：Bipolar disorders

authors： Chuang DM,Chen RW,Chalecka-Franaszek E,Ren M,Hashimoto R,Senatorov V,Kanai H,Hough C,Hiroi T,Leeds P

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Cigarette smoking in individuals with bipolar disorder has been associated with suicidal behavior, although the precise relationship between the two remains unclear. METHODS:In this prospective observational study of 116 individuals with bipolar disorder, we examined the association between smoking and suic...

journal_title：Bipolar disorders

authors： Ostacher MJ,Lebeau RT,Perlis RH,Nierenberg AA,Lund HG,Moshier SJ,Sachs GS,Simon NM

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:Diagnosis and management of bipolar disorder (BD) are limited by the absence of available biomarkers. Allostatic load (AL) represents the strain that stress, including the effects of acute phases and inter-episode chronic mood instability, exerts on interconnected biological systems. This study aimed to oper...

journal_title：Bipolar disorders

authors： Dargél AA,Volant S,Brietzke E,Etain B,Olié E,Azorin JM,Gard S,Bellivier F,Bougerol T,Kahn JP,Roux P,Aubin V,Courtet P,Leboyer M,Henry C,FACE-BD collaborators.

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:The Bipolar Disorders: Improving Diagnosis, Guidance and Education (BRIDGE)-II-Mix study aimed to estimate the frequency of mixed states in patients with a major depressive episode (MDE) according to different definitions. The present post-hoc analysis evaluated the association between obesity and the presen...

journal_title：Bipolar disorders

authors： Petri E,Bacci O,Barbuti M,Pacchiarotti I,Azorin JM,Angst J,Bowden CL,Mosolov S,Vieta E,Young AH,Perugi G,BRIDGE-II-Mix Study Group.

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Although olfactory abnormalities are well established in schizophrenia, considerably less work has examined olfactory performance in other neuropsychiatric conditions. In the current study, we examined odor identification, odor discrimination, detection threshold, and odor hedonic processing performance in i...

journal_title：Bipolar disorders

authors： Kamath V,Paksarian D,Cui L,Moberg PJ,Turetsky BI,Merikangas KR

更新日期：2018-09-01 00:00:00

abstract：:The widely held clinical view of 'antidepressants' as highly effective and specific for the treatment of all types of depressive disorders is exaggerated. This sobering conclusion is supported by recent findings from the NIMH-sponsored STEP-BD and STAR*D projects. Antidepressants have limited short-term efficacy in un...

journal_title：Bipolar disorders

authors： Ghaemi SN

更新日期：2008-12-01 00:00:00

abstract：:Bipolar disorders (BPD) are major, life-long psychiatric illnesses found in 2-5% of the population. Prognosis for BPD was once considered relatively favorable, but contemporary findings suggest that disability and poor outcomes are prevalent, despite major therapeutic advances. Syndromal recovery from acute episodes o...

journal_title：Bipolar disorders

authors： Huxley N,Baldessarini RJ

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:A high prevalence rate of bipolar disorder (BP) comorbid with alcohol dependence (AD) (BP+AD) in Western patients with BP has been reported, but whether this is true for Han Chinese with BP is uncertain. We explored the prevalence of BP+AD in a Han Chinese population with BP, and investigated the effect of a...

journal_title：Bipolar disorders

authors： Chang YH,Lee SY,Wang TY,Chen SL,Tzeng NS,Chen PS,Lee IH,Chen KC,Huang SY,Yang YK,Ko HC,Lu RB

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:In children with pediatric bipolar disorder (PBD), a consistent pattern of elevations in inattention/hyperactivity, depression/anxiety, and aggression has been identified on the Child Behavior Checklist (CBCL-PBD profile). In Germany, no epidemiological study has included PBD to date. OBJECTIVES:To estimate...

journal_title：Bipolar disorders

authors： Holtmann M,Bölte S,Goth K,Döpfner M,Plück J,Huss M,Fegert JM,Lehmkuhl G,Schmeck K,Poustka F

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study has been to examine differences in the laterality of pain in patients with migraine and comorbid unipolar depressive (UP) and bipolar II (BP II) disorders. METHODS:Semi-structured interviews of 102 patients with major affective disorders were conducted, using DSM-IV criteria...

journal_title：Bipolar disorders

authors： Fasmer OB,Oedegaard KJ

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To report a case report of a geriatric patient with a 5-year history of gabapentin use for enhanced bipolar control, who was tapered off of gabapentin over 1 week. The patient displayed unique withdrawal symptoms after the taper of gabapentin. METHODS:The patient is an 81-year-old white female with a life-lo...

journal_title：Bipolar disorders

authors： Tran KT,Hranicky D,Lark T,Jacob Nj

更新日期：2005-06-01 00:00:00

abstract：:With great interest, we have read the recent paper by Keramatian and colleagues entitled "Grey Matter Abnormalities in First Episode Mania: A Systematic Review and Meta-analysis of Voxel-Based Morphometry Studies" in Bipolar Disorders1 . The authors systematically reviewed 15 voxel-based morphometry (VBM) studies and ...

journal_title：Bipolar disorders

authors： Sheng L,Ma H,Dai Z,Yao L,Hu J

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:Affective psychoses and bipolar disorders have been neglected in the development of early intervention strategies. This paper aims to gather current knowledge on the early phase of bipolar disorders in order to define new targets for early intervention. METHODS:Literature review based on the main computerize...

journal_title：Bipolar disorders

authors： Conus P,Ward J,Hallam KT,Lucas N,Macneil C,McGorry PD,Berk M

更新日期：2008-07-01 00:00:00

abstract：:The Diagnostic Guidelines Task Force of the International Society for Bipolar Disorders (ISBD) presents in this document and this special issue a summary of the current nosological status of bipolar illness, a discussion of possible revisions to current DSM-IV and ICD-10 definitions, an examination of the relevant lit...

journal_title：Bipolar disorders

authors： Ghaemi SN,Bauer M,Cassidy F,Malhi GS,Mitchell P,Phelps J,Vieta E,Youngstrom E,ISBD Diagnostic Guidelines Task Force.

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:To compare the dimensional psychopathology in offspring of parents with bipolar disorder (BP) with offspring of community control parents as assessed by the Child Behavior Checklist (CBCL). METHODS:Offspring of parents with BP, who were healthy or had non-BP disorders (any psychiatric disorder other than BP...

journal_title：Bipolar disorders

authors： Diler RS,Birmaher B,Axelson D,Obreja M,Monk K,Hickey MB,Goldstein B,Goldstein T,Sakolsky D,Iyengar S,Brent D,Kupfer D

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:  Inflammation and other immune processes are increasingly linked to psychiatric diseases. Antigenic triggers specific to bipolar disorder are not yet defined. We tested whether antibodies to bovine milk caseins were associated with bipolar disorder, and whether patients recognized different epitopes of the ...

journal_title：Bipolar disorders

authors： Severance EG,Dupont D,Dickerson FB,Stallings CR,Origoni AE,Krivogorsky B,Yang S,Haasnoot W,Yolken RH

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Objective physiological indices independently characterizing affective and schizophreniform psychoses would contribute to our understanding of the nature of their relationships. Magnetoencephalography (MEG)-based metrics of altered structural/functional asymmetry in the superior temporal gyrus have previousl...

journal_title：Bipolar disorders

authors： Reite M,Teale P,Rojas DC,Reite E,Asherin R,Hernandez O

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To determine the impact of acute depression on quality of life (QOL) in patients with bipolar I disorder and to compare these results with published data on QOL in patients with unipolar depression. METHODS:Quality of life was assessed using the SF-36 in bipolar patients (n = 958) who had recently experience...

journal_title：Bipolar disorders

authors： Yatham LN,Lecrubier Y,Fieve RR,Davis KH,Harris SD,Krishnan AA

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:Bipolar disorders are associated with high rates of suicide attempts (SAs) and completions. Several factors have been reported to be associated with suicide in persons with bipolar disorder, but most studies to date have been retrospective and have not utilized multivariate statistics to account for the redu...

journal_title：Bipolar disorders

authors： Marangell LB,Bauer MS,Dennehy EB,Wisniewski SR,Allen MH,Miklowitz DJ,Oquendo MA,Frank E,Perlis RH,Martinez JM,Fagiolini A,Otto MW,Chessick CA,Zboyan HA,Miyahara S,Sachs G,Thase ME

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to determine the role of genetic variations within the zinc finger protein 804A (ZNF804A) gene, a candidate for a psychosis risk-conferring gene, in the development of schizophrenia (SZ) and bipolar disorder (BP) in the Korean population. METHODS:A total of 921 patients with SZ, bipo...

journal_title：Bipolar disorders

authors： Baek JH,Ha K,Kim Y,Yang SY,Cho EY,Choi Y,Ryu S,Lee YS,Park T,Hong KS

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Considerable preclinical biochemical and behavioral data suggest that protein kinase C inhibition would bring about antimanic effects. Notably, the structurally highly dissimilar antimanic agents lithium and valproate, when administered in therapeutically relevant paradigms, attenuate protein kinase C [corre...

journal_title：Bipolar disorders

authors： Zarate CA Jr,Singh JB,Carlson PJ,Quiroz J,Jolkovsky L,Luckenbaugh DA,Manji HK

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To assess rates of conversion to bipolar spectrum disorder (BPSD) and risk factors associated with conversion in children with depressive spectrum disorders (DSD) and transient manic symptoms (TMS) over 18 months. TMS are manic-like symptoms of insufficient duration or number to warrant a diagnosis of BPSD. ...

journal_title：Bipolar disorders

authors： Nadkarni RB,Fristad MA

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:We conducted a study of clinical presentation and family history in patients responsive to either of two commonly used mood stabilizers, lithium and lamotrigine. METHODS:The sample included 164 subjects from 21 families of bipolar probands, 14 responders to lithium and seven to lamotrigine. Diagnostic inform...

journal_title：Bipolar disorders

authors： Passmore MJ,Garnham J,Duffy A,MacDougall M,Munro A,Slaney C,Teehan A,Alda M

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Suicide is a multicausal human behavior, with devastating and immensely distressing consequences. Its prevalence is estimated to be 20-30 times greater in patients with bipolar disorders than in the general population. The burden of suicide and its high prevalence in bipolar disorders make it imperative th...

journal_title：Bipolar disorders

authors： Malhi GS,Outhred T,Das P,Morris G,Hamilton A,Mannie Z

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:The serotonin hypothesis plays a critical role in the etiology of bipolar disorder (BD). Although many studies have demonstrated reciprocal relationships between serotonin metabolism and immune-inflammatory pathways that occur in depression, studies linking serotonergic function and cytokines are still limit...

journal_title：Bipolar disorders

authors： Hsu JW,Lirng JF,Wang SJ,Lin CL,Yang KC,Liao MH,Chou YH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:We sought to determine whether the risk of relapse in patients with bipolar disorder is higher after discontinuation and restart of lithium treatment as compared to continuous lithium treatment in these same patients. METHODS:We conducted literature searches in the Pubmed, Embase, Cochrane, and PsycINFO dat...

journal_title：Bipolar disorders

authors： de Vries C,van Bergen A,Regeer EJ,Benthem E,Kupka RW,Boks MP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:The question of whether there is a continuum or a dichotomy among patients with schizophrenia (SZ) and bipolar disorders (BD) has not been clearly resolved and remains a challenge. Thus, the identification of specific biomarkers of these disorders might be helpful. The present study investigated the volume o...

journal_title：Bipolar disorders

authors： Tréhout M,Leroux E,Delcroix N,Dollfus S

更新日期：2017-09-01 00:00:00