Psychosocial treatments for bipolar disorder: cost-effectiveness, mediating mechanisms, and future directions.

abstract：OBJECTIVES:Although olfactory abnormalities are well established in schizophrenia, considerably less work has examined olfactory performance in other neuropsychiatric conditions. In the current study, we examined odor identification, odor discrimination, detection threshold, and odor hedonic processing performance in i...

journal_title：Bipolar disorders

authors： Kamath V,Paksarian D,Cui L,Moberg PJ,Turetsky BI,Merikangas KR

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:To investigate the use of transcranial direct current stimulation (tDCS) for enhancing working memory and sustained attention in euthymic patients with bipolar disorder. METHODS:Fifteen patients with bipolar disorder received anodal left prefrontal tDCS with an extracephalic cathode (prefrontal condition), ...

journal_title：Bipolar disorders

authors： Martin DM,Chan HN,Alonzo A,Green MJ,Mitchell PB,Loo CK

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to determine the role of genetic variations within the zinc finger protein 804A (ZNF804A) gene, a candidate for a psychosis risk-conferring gene, in the development of schizophrenia (SZ) and bipolar disorder (BP) in the Korean population. METHODS:A total of 921 patients with SZ, bipo...

journal_title：Bipolar disorders

authors： Baek JH,Ha K,Kim Y,Yang SY,Cho EY,Choi Y,Ryu S,Lee YS,Park T,Hong KS

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Although second-generation antipsychotics (SGAs) are widely used in treating schizophrenia and bipolar disorder, their effects on dyslipidemia, glucose intolerance, metabolic syndrome (MetS), and coronary heart disease (CHD) risk are less well documented for bipolar disorder. We compared bipolar disorder and ...

journal_title：Bipolar disorders

authors： Correll CU,Frederickson AM,Kane JM,Manu P

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Lithium is often the mood stabilizer of choice for the treatment of type I bipolar disorder. However, side effects as well as the narrow therapeutic dosing range often complicate its use. Lithium toxicity can be fatal and its serum level needs to be closely monitored, especially at the time of introduction a...

journal_title：Bipolar disorders

authors： Lazarczyk MJ,Giannakopoulos P

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Bipolar disorder is frequently associated with cognitive impairment even during euthymia. Previous studies have reported significant impairments in functional and quality of life outcomes and a possible relationship between these variables and cognitive performance. Cognitive rehabilitation interventions hav...

journal_title：Bipolar disorders

authors： Gomes BC,Rocca CC,Belizario GO,de B F Fernandes F,Valois I,Olmo GC,Fachin RVP,Farhat LC,Lafer B

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:This study compared the relative risk for hospitalization of patients with bipolar and manic disorders receiving atypical and typical antipsychotics. METHODS:This retrospective study was based on administrative claims data extracted from the PharMetrics database during 1999 through 2003. Comparisons were ma...

journal_title：Bipolar disorders

authors： Gianfrancesco F,Rajagopalan K,Goldberg JF,Wang RH

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Patients with mood disorders may benefit from psychosocial interventions through changes in brain networks underlying emotion processing. In this study, we used functional magnetic resonance imaging (fMRI) to investigate treatment-related changes in emotion processing networks in youth at familial high risk ...

journal_title：Bipolar disorders

authors： Garrett AS,Chang KD,Singh MK,Armstrong CC,Walshaw PD,Miklowitz DJ

更新日期：2021-01-12 00:00:00

abstract：OBJECTIVES:Mismatch negativity (MMN) and its magnetic counterpart (MMNm) are thought to reflect an automatic process that detects a difference between an incoming stimulus and the sensory memory trace of preceding stimuli. In patients with schizophrenia, an attenuation of the MMN/MMNm amplitude has been repeatedly repo...

journal_title：Bipolar disorders

authors： Shimano S,Onitsuka T,Oribe N,Maekawa T,Tsuchimoto R,Hirano S,Ueno T,Hirano Y,Miura T,Kanba S

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Population isolates offer several advantages for those hoping to identify predisposition genes for bipolar disorder (BP). In this review article, the rationale for performing gene mapping studies in this type of population and the results of genetic mapping studies performed to date in population isolates ar...

journal_title：Bipolar disorders

authors： Escamilla MA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:In this report, we seek to (i) identify a potential neuroimaging endophenotype for bipolar disorder (BD) in emotion regulatory and autonomic circuitry in young first-degree relatives of persons with BD; and (ii) replicate our previous work identifying the functional neuroanatomy of working memory (WM) in an ...

journal_title：Bipolar disorders

authors： Thermenos HW,Makris N,Whitfield-Gabrieli S,Brown AB,Giuliano AJ,Lee EH,Faraone SV,Tsuang MT,Seidman LJ

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To investigate whether first admission with mania is associated with the occurrence of death in the family or with major stressful life events and to explore whether the associations change with age. METHODS:Case register study with linkage of the Danish Psychiatric Central Research Register, including data...

journal_title：Bipolar disorders

authors： Kessing LV,Agerbo E,Mortensen PB

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Topiramate, a newer antiepileptic agent, may benefit several neurological and psychiatric states, including bipolar disorder. CASE REPORT:A physically healthy, stockily built, 47-year-old, hypomanic Asian male with a >20-year history of uneventful use of psychotropic agents received topiramate in a dose tha...

journal_title：Bipolar disorders

authors： Andrade C

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:Caregivers of people with bipolar disorder often have depression and health problems. This study aimed to evaluate the sustained effects of a 12-15 week psychoeducational intervention on the health and mental health of caregivers of persons with bipolar disorder. We also evaluated the effects of the interven...

journal_title：Bipolar disorders

authors： Perlick DA,Jackson C,Grier S,Huntington B,Aronson A,Luo X,Miklowitz DJ

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset. METHOD:Data ...

journal_title：Bipolar disorders

authors： Bauer M,Glenn T,Alda M,Andreassen OA,Ardau R,Bellivier F,Berk M,Bjella TD,Bossini L,Del Zompo M,Dodd S,Fagiolini A,Frye MA,Gonzalez-Pinto A,Henry C,Kapczinski F,Kliwicki S,König B,Kunz M,Lafer B,Lopez-Jaramillo C

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Experts have debated the ability of patients with bipolar illness to consent to research participation when manic. We compared 25 euthymic bipolar and 26 manic bipolar patients in their understanding of three hypothetical studies of varying complexity. METHODS:Hypothetical studies were presented as written ...

journal_title：Bipolar disorders

authors： Misra S,Socherman R,Park BS,Hauser P,Ganzini L

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:We combined multimodal functional magnetic resonance imaging (fMRI) and structural magnetic resonance imaging to probe abnormalities in brain circuits underpinning episodic memory performance deficits in patients with bipolar disorder (BD). METHODS:We acquired whole-brain fMRI data in 21 patients with BD an...

journal_title：Bipolar disorders

authors： Oertel-Knöchel V,Reinke B,Feddern R,Knake A,Knöchel C,Prvulovic D,Pantel J,Linden DE

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Bipolar major depression differs considerably from unipolar major depression with regard to the efficacy of treatment with antidepressants. In bipolar depression, response to treatment with antidepressants is disappointing. Whether response to electroconvulsive therapy (ECT) differs between bipolar and unipol...

journal_title：Bipolar disorders

authors： Dierckx B,Heijnen WT,van den Broek WW,Birkenhäger TK

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Although it is well established that euthymic patients with bipolar disorder can have cognitive impairment, substantial heterogeneity exists and little is known about the extent and severity of impairment within the bipolar II disorder subtype. Therefore, the main aim of this study was to analyze cognitive v...

journal_title：Bipolar disorders

authors： Solé B,Jiménez E,Torrent C,Del Mar Bonnin C,Torres I,Reinares M,Priego Á,Salamero M,Colom F,Varo C,Vieta E,Martínez-Arán A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:The notion that sufferers of bipolar disorder achieve complete syndromal and functional recovery between illness episodes has been brought into question by evidence that a large proportion of patients fail to regain premorbid levels of functioning after the resolution of major affective symptoms. A growing b...

journal_title：Bipolar disorders

authors： Robinson LJ,Ferrier IN

更新日期：2006-04-01 00:00:00

abstract：:Lithium, the major drug used to treat manic depressive illness, robustly protects cultured rat brain neurons from glutamate excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptors. The lithium neuroprotection against glutamate excitotoxiciy is long-lasting, requires long-term pretreatment and occurs at therap...

journal_title：Bipolar disorders

authors： Chuang DM,Chen RW,Chalecka-Franaszek E,Ren M,Hashimoto R,Senatorov V,Kanai H,Hough C,Hiroi T,Leeds P

更新日期：2002-04-01 00:00:00

abstract：:Research into postnatal mood disorders to date has concentrated on depressive syndromes of varying severity and full-blown acute puerperal mania. However, clinical experience, backed up by a review of the literature, indicates that milder hypomanic symptoms also occur in the early puerperium. Although these symptoms m...

journal_title：Bipolar disorders

authors： Heron J,Craddock N,Jones I

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:Several lines of evidence suggest that deficits in cognition persist in bipolar patients during periods of euthymia. Working memory impairment has been observed in euthymic bipolar patients and noted to be a significant source of functional deficits in psychiatric disorders. Functional changes associated wit...

journal_title：Bipolar disorders

authors： Adler CM,Holland SK,Schmithorst V,Tuchfarber MJ,Strakowski SM

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:Despite known metabolic effects of second-generation antipsychotics (SGAs) on children and adolescents, comparative effects in youth with different diagnoses remain underreported. We compared differences in metabolic changes three months after starting treatment with SGAs in youth with bipolar disorder and w...

journal_title：Bipolar disorders

authors： Moreno C,Merchán-Naranjo J,Alvarez M,Baeza I,Alda JA,Martínez-Cantarero C,Parellada M,Sánchez B,de la Serna E,Giráldez M,Arango C

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Studies have suggested that episode polarity at illness onset in bipolar disorder may be predictive of some aspects of lifetime clinical characteristics. We here examine this possibility in a large, well-characterized sample of patients with bipolar I disorder. METHODS:We assessed polarity at onset in patie...

journal_title：Bipolar disorders

authors： Forty L,Jones L,Jones I,Smith DJ,Caesar S,Fraser C,Gordon-Smith K,Hyde S,Craddock N

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The present study examined the 5-year longitudinal course of cognitive functioning in a large sample of well-characterized patients with bipolar disorder (BP), compared to healthy controls (HCs), and the influence of cognitive reserve factors (e.g., education and IQ) on cognitive change over time. METHODS:P...

journal_title：Bipolar disorders

authors： Hinrichs KH,Easter RE,Angers K,Pester B,Lai Z,Marshall DF,Kamali M,McInnis M,Langenecker SA,Ryan KA

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The question of whether there is a continuum or a dichotomy among patients with schizophrenia (SZ) and bipolar disorders (BD) has not been clearly resolved and remains a challenge. Thus, the identification of specific biomarkers of these disorders might be helpful. The present study investigated the volume o...

journal_title：Bipolar disorders

authors： Tréhout M,Leroux E,Delcroix N,Dollfus S

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Evaluate the efficacy and tolerability of quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) in the treatment of acute mania. METHODS:Patients were randomized to 21 days of double-blind treatment with QTP plus Li/DVP, or placebo (PBO) plus Li/DVP. QTP was rapidly dosed up to a maximum of 800 mg/...

journal_title：Bipolar disorders

authors： Sachs G,Chengappa KN,Suppes T,Mullen JA,Brecher M,Devine NA,Sweitzer DE

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Studies into social cognition in psychiatric disorders have recently been expanded to address the question of whether or not theory of mind (ToM), i.e., the ability to represent ones own and others mental states, is impaired in bipolar affective disorder (BPD). Results have been mixed so far, mainly due to p...

journal_title：Bipolar disorders

authors： Wolf F,Brüne M,Assion HJ

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:Suicide is a multicausal human behavior, with devastating and immensely distressing consequences. Its prevalence is estimated to be 20-30 times greater in patients with bipolar disorders than in the general population. The burden of suicide and its high prevalence in bipolar disorders make it imperative th...

journal_title：Bipolar disorders

authors： Malhi GS,Outhred T,Das P,Morris G,Hamilton A,Mannie Z

更新日期：2018-06-01 00:00:00