N-Ethylmaleimide sensitive factor in the cortex of subjects with schizophrenia and bipolar I disorder.

abstract：:gamma-Interferon (IFN-gamma) is known to induce expression of major histocompatibility complex (MHC) class II antigens on murine astrocytes and MHC class I antigens on murine oligodendrocytes. We studied whether the human IFN-gamma could induce the expression of Human Leukocyte Antigen (HLA)-A, B, C and -DR antigens o...

journal_title：Neuroscience letters

authors： Hirayama M,Yokochi T,Shimokata K,Iida M,Fujiki N

更新日期：1986-12-23 00:00:00

abstract：:Galanin- and bethanechol-activated whole cell currents were studied in dissociated mudpuppy parasympathetic neurons kept in 12.5 mM KCl. The bethanechol-induced current was reduced when generated during a galanin-induced current. The galanin and bethanechol currents reversed at -45 mV and exhibited inward rectificatio...

journal_title：Neuroscience letters

authors： Parsons RL,Merriam LA

更新日期：1992-06-08 00:00:00

abstract：:To investigate changes in regional cerebral blood flow (rCBF) under the prone condition with and without light massage on the back, we measured rCBF quantitatively in healthy human subjects using positron emission tomography with H(2)15O. Biochemical tests showed that the light massage (palm-pressure) reduced levels o...

journal_title：Neuroscience letters

authors： Ouchi Y,Kanno T,Okada H,Yoshikawa E,Shinke T,Nagasawa S,Minoda K,Doi H

更新日期：2006-10-23 00:00:00

abstract：:Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

journal_title：Neuroscience letters

authors： Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

更新日期：2012-11-14 00:00:00

abstract：:With the use of the microdialysis technique, we examined the modulatory effect of ketamine on catecholamine efflux from in vivo cardiac sympathetic nerve endings. A dialysis probe was implanted in the left ventricular myocardium, and dialysate norepinephrine (NE) levels in anesthetized cats were measured with liquid c...

journal_title：Neuroscience letters

authors： Kitagawa H,Yamazaki T,Akiyama T,Yahagi N,Kawada T,Mori H,Sunagawa K

更新日期：2002-05-24 00:00:00

abstract：:Tryptophan hydroxylase 2 (TPH2) catalyzes the rate-limiting step in the synthesis of brain serotonin (5-HT). In a previous report, a single nucleotide polymorphism in mTph2 (C1473G) reduced 5-HT synthesis by 55%. Mouse strains expressing the 1473C allele, such as C57Bl/6, have higher 5-HT synthesis rates than strains ...

journal_title：Neuroscience letters

authors： Siesser WB,Zhang X,Jacobsen JP,Sotnikova TD,Gainetdinov RR,Caron MG

更新日期：2010-08-30 00:00:00

abstract：:Hippocampal volumetry has been proposed to aid in the early diagnosis of Alzheimer's disease (AD) and to monitor progression of the disease. While this is believed to be as a result of hippocampal neuron loss, this association has not been firmly established and loss of other tissue elements may be responsible for the...

journal_title：Neuroscience letters

authors： Kril JJ,Hodges J,Halliday G

更新日期：2004-05-06 00:00:00

abstract：:In an effort to analyze the genetic role of tau in Alzheimer's disease (AD), 17 polymorphisms were identified. Eleven of these polymorphisms were in complete linkage disequilibrium and segregated as two haplotypes, A and B. The A and B haplotypes were investigated in 269 AD cases and 238 controls from two different so...

journal_title：Neuroscience letters

authors： Lilius L,Froelich Fabre S,Basun H,Forsell C,Axelman K,Mattila K,Andreadis A,Viitanen M,Winblad B,Fratiglioni L,Lannfelt L

更新日期：1999-12-17 00:00:00

abstract：:The paper focuses on such candidate gene polymorphisms that alter alcoholism-related intermediate phenotypes including: dopaminergic system polymorphic variants (DRD2 -141C Ins/Del in promoter region, exon 8 and DRD2 TaqI A and DAT 40bp VNTR genes polymorphisms) that cause predisposition to severe alcoholism (haplotyp...

journal_title：Neuroscience letters

authors： Samochowiec J,Kucharska-Mazur J,Grzywacz A,Jabłoński M,Rommelspacher H,Samochowiec A,Sznabowicz M,Horodnicki J,Sagan L,Pełka-Wysiecka J

更新日期：2006-12-13 00:00:00

abstract：:Localization of 5-hydroxytryptamine immunoreactivity was studied in the rat coeliac-superior mesenteric ganglion complex and in the porcine superior and inferior mesenteric ganglia by the indirect immunofluorescence technique. In normal rats, only 5-hydroxytryptamine immunoreactive SIF cells were seen in the coeliac-s...

journal_title：Neuroscience letters

authors： Karhula T,Soinila S,Lakomy M,Majewski M,Kaleczyk J,Häppölä O

更新日期：1995-07-14 00:00:00

abstract：:This study reports the solubilization of the rat synaptic vesicle protein SV2A, the brain binding site for the antiepileptic drug levetiracetam (LEV), and its characterization. N-dodecyl-beta-D-maltoside (DDM) was the best detergent at achieving a high percentage of SV2A solubilization and at maintaining the binding c...

journal_title：Neuroscience letters

authors： Lambeng N,Grossmann M,Chatelain P,Fuks B

更新日期：2006-05-01 00:00:00

abstract：:Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium in BPD seem to involve a direct regulation of neurotrophic cascades. However, no clinical study e...

journal_title：Neuroscience letters

authors： de Sousa RT,van de Bilt MT,Diniz BS,Ladeira RB,Portela LV,Souza DO,Forlenza OV,Gattaz WF,Machado-Vieira R

更新日期：2011-04-20 00:00:00

abstract：:The gamma-aminobutyric acid (GABA) antagonist (+/-)-bicuculline inhibits specific [3H]strychnine binding to postsynaptic glycine receptor sites in rat spinal cord synaptosomal membranes with an inhibition constant of about 5 microM, which is fairly similar to its inhibition constant reported for the GABA receptor. Thi...

journal_title：Neuroscience letters

authors： Goldinger A,Müller WE

更新日期：1980-01-01 00:00:00

abstract：:Previous studies have observed increased tachykinin NK(1) receptor immunoreactivity (NK(1)-IR) in the prefrontal cortex in subjects with schizophrenia. Since the subjects were medicated the possibility of a treatment effect could not be excluded. Thus, the present study was undertaken to determine the effect of chroni...

journal_title：Neuroscience letters

authors： Tooney PA,Anderson WB,Lynch-Frame A,Chahl LA

更新日期：2005-07-22 00:00:00

abstract：:Neural cell adhesion molecules (NCAMs) are members of the immunoglobulin superfamily and are involved in synaptic rearrangements in the mature brain. There are three major NCAM forms: NCAM 180, NCAM 140 and NCAM 120. Several studies report that NCAMs play a central role in memory. In the present study we investigated ...

journal_title：Neuroscience letters

authors： Baydas G,Nedzvetsky VS,Nerush PA,Kirichenko SV,Demchenko HM,Reiter RJ

更新日期：2002-06-28 00:00:00

abstract：:By combining techniques designed to increase the amount of horseradish peroxidase (HRP) available for transport and to improve the sensitivity of the reaction for detecting HRP, we have produced an anterograde HRP technique suitable for labeling sparse efferent projections. The efficacy of this light, microscopic tech...

journal_title：Neuroscience letters

authors： West JR,Black AC Jr

更新日期：1979-04-01 00:00:00

abstract：:We have looked at the effect of synthetic mu-conotoxin GIIIA, a selective blocker of muscle Na channels, on various parameters of synaptic transmission at the frog sartorius nerve-muscle preparation. We found that 5 microM mu-conotoxin consistently blocked muscle action potentials, but had no effect on nerve action po...

journal_title：Neuroscience letters

authors： Sosa MA,Zengel JE

更新日期：1993-07-23 00:00:00

abstract：:Traumatic brain injury is associated with behavioral deficits, often in the absence of histopathological or ultrastructural changes. To determine whether membrane remodeling occurs, immunocytochemical techniques were used and the density and distribution of GAP-43 were measured. GAP-43 is a membrane-bound protein, whi...

journal_title：Neuroscience letters

authors： Hulsebosch CE,DeWitt DS,Jenkins LW,Prough DS

更新日期：1998-10-16 00:00:00

abstract：:Intellectual disability (ID) is one of the most prevalent chronic developmental brain disorders or phenotype of syndromic ID, affecting nearly 1-2% of the general population worldwide. Over recent decades, tremendous effort and high-throughput platforms have been devised to explore the complex heterogeneity, numerous ...

journal_title：Neuroscience letters

authors： Chen C,Chen D,Xue H,Liu X,Zhang T,Tang S,Li W,Xu X

更新日期：2018-10-15 00:00:00

abstract：:Visual mental imagery is a process that draws on different cognitive abilities and is affected by the contents of mental images. Several studies have demonstrated that different brain areas subtend the mental imagery of navigational and non-navigational contents. Here, we set out to determine whether there are distinc...

journal_title：Neuroscience letters

authors： Boccia M,Piccardi L,Palermo L,Nemmi F,Sulpizio V,Galati G,Guariglia C

更新日期：2014-09-05 00:00:00

abstract：:While past research suggests that ghrelin stimulates appetite through an action on hypothalamic signaling, recent evidence indicates that the peptide acts via mesotelencephalic dopamine neurons to alter appetitive motivation. In the present study, rats were trained to operantly respond for food on a progressive ratio ...

journal_title：Neuroscience letters

authors： Weinberg ZY,Nicholson ML,Currie PJ

更新日期：2011-07-20 00:00:00

abstract：:Nociceptin/orphanin FQ (NC) and its receptor (OP(4)) have been implicated in the regulation of various functions including nociception. [Nphe(1)]NC(1-13)NH(2) (Nphe) is a selective OP(4) antagonist which prevents the pronociceptive effects of supraspinal NC and causes per se a naloxone-insensitive antinociceptive effe...

journal_title：Neuroscience letters

authors： Di Giannuario A,Rizzi A,Pieretti S,Guerrini R,Bertorelli R,Salvadori S,Regoli D,Calo G

更新日期：2001-12-04 00:00:00

abstract：:Both chronic pain and depression are debilitating diseases, which often coexist in clinic. However, current analgesics and antidepressants exhibit limited efficacy for this comorbidity. The present study aimed to investigate the effect of ketamine on the comorbidity of inflammatory pain and consequent depression-like ...

journal_title：Neuroscience letters

authors： Zhang GF,Wang J,Han JF,Guo J,Xie ZM,Pan W,Yang JJ,Sun KJ

更新日期：2016-09-19 00:00:00

abstract：:A method for the histochemical demonstration of cells with the capacity to synthesize the enzyme GABA-transaminase is described. Intraventricular injection of ethanolamine-O-sulfate irreversibly inhibits brain GABA-transaminase activity. Within 17 h after the injection sufficient new enzyme is synthesized to allow his...

journal_title：Neuroscience letters

authors： Vincent SR,Kimura H,McGeer EG

更新日期：1980-03-01 00:00:00

abstract：:Following peripheral nerve section, the cell body and proximal axon undergo various physiological and morphological changes which may be associated with regrowth. We found that axotomy reduced the amplitude and duration of the afterhyperpolarization (AHP) of the action potential (AP) of bullfrog sympathetic neurones. ...

journal_title：Neuroscience letters

authors： Kelly ME,Gordon T,Shapiro J,Smith PA

更新日期：1986-06-18 00:00:00

abstract：:Aging is associated with cognitive deterioration. A recent study showed two polymorphisms (rs505058 in LMNA and rs11622883 near a SERPINA13 gene), identified in a genome-wide association study of late-onset Alzheimer's disease, to be associated with cognitive function (Mini Mental State Examination) in a UK elderly po...

journal_title：Neuroscience letters

authors： Yeh HL,Hou SJ,Yen FC,Hong CJ,Liou YJ,Yang AC,Liu ME,Tsai SJ

更新日期：2011-10-17 00:00:00

abstract：:In this study, we have developed a microarray including 1467 cDNAs that were selected to specifically measure stress response in peripheral blood leukocytes. Venous blood was collected from 10 graduate students 2 h before and 2 or 24 h after an open presentation for their Ph.D. The mRNA levels in leukocytes were compa...

journal_title：Neuroscience letters

authors： Morita K,Saito T,Ohta M,Ohmori T,Kawai K,Teshima-Kondo S,Rokutan K

更新日期：2005-06-10 00:00:00

abstract：:To investigate the capacity of the central nervous system to integrate and differentiate two different muscular fatigue states, the present study examines the changes on multi-joint movement organization following muscular fatigue of elbow extensor muscles (triceps brachii) induced by voluntary versus electrically ind...

journal_title：Neuroscience letters

authors： Huffenus AF,Forestier N

更新日期：2006-07-31 00:00:00

abstract：:The projection of tooth pulp afferents in the spinal trigeminal nucleus (N.V.sp.) and the effect of dorsolateral medullotomy on cortical potentials evoked by electrical stimulation of Adelta tooth pulp nerve fibres were studied in cats. It was confirmed that antidromic responses were recorded in the tooth pulp nerve t...

journal_title：Neuroscience letters

authors： Keller O,Kalina M,Ujec E,Zivný A,Vyklický L

更新日期：1981-09-25 00:00:00

abstract：:Electrical stimulation (20-35 Hz, 2-5 V, 1.5 h) of the pelvic nerve in urethane-anesthetized rats increased the expression of c-fos protein-immunoreactivity primarily in neurons in the L6-S1 segments of the spinal cord. The neurons were localized to areas receiving afferent input from the pelvic viscera including the ...

journal_title：Neuroscience letters

authors： Birder LA,Roppolo JR,Iadarola MJ,de Groat WC

更新日期：1991-08-19 00:00:00