Abstract:
OBJECTIVE:To review the main causes of new bronchopulmonary dysplasia and the strategies utilized to decrease its incidence in extremely low birth weight infants. SOURCES OF DATA:For this review a MEDLINE search from 1966 to October 2004, the Cochrane Database, abstracts from the Society for Pediatric Research and recent meetings on the topic were used. SUMMARY OF THE FINDINGS:The survival of extremely low birth weight infants has increased significantly due to improvement in both scientific knowledge and technology. This improvement in survival has therefore resulted in an increased incidence of bronchopulmonary dysplasia. The characteristics of bronchopulmonary dysplasia in extremely low birth weight infants, the so called "new" bronchopulmonary dysplasia are quite different from the classic bronchopulmonary dysplasia described by Northway. This new bronchopulmonary dysplasia has a multifactorial etiology, which includes volutrauma, atelectrauma, oxygen toxicity and lung inflammation. Therapy such as prenatal corticosteroids, exogenous surfactant, nasal continuous positive airway pressure, new mechanical ventilation modalities and gentle ventilation have been used in attempts to decrease lung injury severity. CONCLUSIONS:In order to prevent lung injury in extremely low birth weight infants, it is necessary to minimize several factors that induce bronchopulmonary dysplasia and to utilize less aggressive therapeutic strategies. In addition to the current therapy used to decrease lung injury, knowledge of these causative factors may create new therapies that may be fundamental in improving the clinical outcomes of premature infants.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Suguihara C,Lessa ACdoi
10.2223/1304keywords:
subject
Has Abstractpub_date
2005-03-01 00:00:00pages
S69-78issue
1 Suppleissn
0021-7557issn
1678-4782journal_volume
81pub_type
杂志文章,评审abstract::OBJECTIVES: The aims of this review are to present research data about aerosoltherapy and to discuss the optimization of this form of drug administration.METHOD: Review of the literature, covering some of the most important studies about aerosoltherapy, inhaler devices, pharmacokinetics and pharmacodynamics of inhaled...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.428
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To analyze the available evidence regarding the efficacy of interventions on parents whose children were aged 2-5 years to promote parental competence and skills for children's healthy lifestyles. SOURCE:Articles published in English and Spanish, available at PubMed, Psycinfo, CINAHL, Web of Science, Eric, a...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2017.07.019
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between the genetic polymorphism of the tumor necrosis factor-alpha (TNF-α) gene and the development of sepsis and septic shock in Thai pediatric patients and to investigate the clinical impacts of TNF-α polymorphisms in this population. METHODS:To perform this genetic associatio...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2216
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To study the etiology of exanthema cases, with or without fever, in children seen in the emergency room of a hospital located in a region where dengue is endemic. METHODS:Enrollment took place between 21/09/2001 and 20/09/2002 and included 95.9% (71/74) of children presenting with exanthema at the emergency ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1522
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of im...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2020.10.009
更新日期:2020-11-22 00:00:00
abstract:OBJECTIVE:To review the new options in insulin therapy for controlling diabetes mellitus in children and adolescents. SOURCES:Articles indexed in PubMed were located using the search terms insulin analogs in children and adolescents and reviewed. Information was also obtained from American Diabetes Association and Soc...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1712
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of pain, musculoskeletal syndromes, orthopedic disorders and using computers and playing videogames among obese adolescents. METHODS:This was a cross-sectional study that investigated 100 consecutive obese adolescents and 100 healthy-weight controls using a confidential, self-repo...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.2111
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To identify the relationship between admission hyperglycemia and outcome in children with severe brain injury at hospital discharge and 6 months later. METHOD:A retrospective analysis of blood glucose levels was conducted in 61 children with severe brain injury admitted to the Pediatric Intensive Care Unit b...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2097
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To describe the current scientific knowledge on the effects of physical exercise on the growth of children and adolescents since intrauterine life. SOURCE OF DATA:A search was carried out in the Medline, Embase, Scielo, and Cochrane databases of studies published from 1990 to 2018. The authors included studi...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2018.11.003
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To present a wide-ranging review of the literature on broncopulmonary dysplasia, covering new definitions, pathophysiology, prevention, treatment, prognosis and progression. SOURCES OF DATA:The most relevant articles published on the subject since it was first described in 1967 were selected from MEDLINE sea...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Plastic bronchitis is an unusual condition in children, associated with formation of mucofibrinous casts and mucous plugging of the tracheobronchial tree. Given that this illness is part of the differential diagnosis of acute respiratory failure, early treatment is important for improved prognosis. The aim of...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1425
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the alterations of heart rate, blood pressure, psychological aspects and oxygen saturation after continuous fenoterol inhalation (0.5 mg/Kg) by children with severe acute asthma. METHODS:We studied 30 patients with severe acute asthma who were treated at the pediatric ward of Hospital Universitár...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To assess pulmonary function in children and adolescents subjected to correction of rheumatic valve disease in order to quantify changes caused by factors inherent to surgery and rheumatic heart disease. METHODS:This was a longitudinal and quantitative intervention study, undertaken at a children's hospital ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1462
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:Streptococcus pneumoniae usually colonizes the oropharynx of healthy people. Oropharyngeal carriage is related to the invasion of adjacent structures and to the development of invasive disease. A descriptive cross-sectional study was performed aiming at verifying the prevalence of oropharyngeal colonization b...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of salbutamol administration by metered-dose inhaler with a home-made spacer versus jet nebulizer in children with moderate wheezing attacks. MATERIAL AND METHODS:A randomized, single-blinded trial was performed with a convenience sample of children presenting wheezing. The child...
journal_title:Jornal de pediatria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To analyze the implementation of a protocol proposed by the Brazilian National Health Surveillance Agency (Agência Nacional de Vigilância Sanitária - ANVISA) to improve sepsis diagnosis in very low birth weight newborns. METHODS:This was a prospective study that evaluated the implementation of a protocol inv...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.01.009
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS:Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis)...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.03.006
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the effect of different ergonomic desk designs and pencil grip patterns on handwriting performance in children with hemiplegic cerebral palsy and healthy children. METHODS:Twenty-six children with left hemiplegic cerebral palsy and 32 typically developing children wer...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1914
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To study epidemiological and clinical aspects of American visceral leishmaniasis in hospitalized children in Ceará, Brazil. METHODS:A retrospective and observational study was carried out with children suffering from American visceral leishmaniasis admitted to Hospital Infantil Albert Sabin in Fortaleza. Med...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::OBJECTIVE: Neonatal tetanus is an infection with high mortality, constituting a problem in underdeveloped countries, where there is faulty prenatal attendance. In spite of this and of the decreasing incidence of the disease in the state of Rio Grande do Sul, we report a case of neonatal tetanus identified in 1997. MET...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.80
更新日期:2000-09-01 00:00:00
abstract::OBJECTIVES: To identify rubella prevalence in different ages and population groups and rubella susceptibility of pregnant and postpartum women according to age, number of children and spontaneous abortion. METHODS: Cross-sectional study of sero-survey type. Children and students were selected in day-care centers and s...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.470
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To analyze the parents' perception of their infants hospitalization in a neonatal intensive care unit (NICU) and suggest a more humane and individualized care in this highly stressful environment. METHODS:We recorded and analyzed the interview of 20 young, low socioeconomic class couples having their first b...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.543
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the trend of pneumonia mortality in Brazilian children aged 4 years and younger from 1991 to 2007. METHODS:We conducted a retrospective study based on the database of the IT Department of the Brazilian Unified Health System (DATASUS), from which we obtained the number of deaths from pneumonia and...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2070
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To present an up-to-date and critical review regarding food allergies, focusing mainly on treatment and prevention. SOURCES:Review of published literature searched on MEDLINE database; those data which were the most up-to-date and representative were selected (2000-2006). The search included the European Soc...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1587
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To compare two groups of school age girls from different social strata were compared in terms of their perception and knowledge about breastfeeding. METHODS:A structured questionnaire was applied to all 346 4th to 8th grade girls attending two schools, a private one, whose students belonged to the upper clas...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::OBJECTIVE: To present current concepts about the diagnosis of recurrent abdominal pain and to review the basis of the therapeutic approach for this disease in children and adolescents. METHODS: References were obtained from the Medline, from recent review articles, and from personal files. Books and dissertations were...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.150
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:To find evidence of the symptoms of anxiety/depression in children with developmental coordination disorder as compared to their typically developing peers at both the group and individual level, and to identify how many different tools are used to measure anxiety and/or depression. METHODS:Electronic search...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2019.03.002
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:The modified shuttle test is a field test that avoids the ceiling effect, and there are no reports of a multidimensional assessment concerning physical activity in asthmatic patients. Thus, the aim was to evaluate functional capacity by MST, additionally to perform a multidimensional assessment as physical ac...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2018.07.011
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To present a new branch of scientific knowledge, known as the developmental origins of health and disease (DOHaD), covering its concepts, study methods and ethical considerations in addition to the prospects for this area of knowledge. SOURCES:A non-systematic review of the biomedical literature intended to ...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1728
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To investigate risk factors for anemia in infants assisted by public health services. METHODS:In a cross-sectional study carried out in Viçosa, state of Minas Gerais, Brazil, 205 children from 6 to 12 months were evaluated. Socioeconomic, environmental and biological data were collected, as well as informati...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1603
更新日期:2007-03-01 00:00:00