Colloidal nanocrystal heterostructures with linear and branched topology.

abstract：:Sex in mammals is determined in the fetal gonad by the presence or absence of the Y chromosome gene Sry, which controls whether bipotential precursor cells differentiate into testicular Sertoli cells or ovarian granulosa cells. This pivotal decision in a single gonadal cell type ultimately controls sexual differentiat...

journal_title：Nature

authors： Matson CK,Murphy MW,Sarver AL,Griswold MD,Bardwell VJ,Zarkower D

更新日期：2011-07-20 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-10-01 00:00:00

abstract：:Most of the 470-million-year history of plants on land belongs to bryophytes, pteridophytes and gymnosperms, which eventually yielded to the ecological dominance by angiosperms 90 Myr ago. Our knowledge of angiosperm phylogeny, particularly the branching order of the earliest lineages, has recently been increased by t...

journal_title：Nature

authors： Pryer KM,Schneider H,Smith AR,Cranfill R,Wolf PG,Hunt JS,Sipes SD

更新日期：2001-02-01 00:00:00

abstract：:Water-driven fracture propagation beneath supraglacial lakes rapidly transports large volumes of surface meltwater to the base of the Greenland Ice Sheet. These drainage events drive transient ice-sheet acceleration and establish conduits for additional surface-to-bed meltwater transport for the remainder of the melt ...

journal_title：Nature

authors： Stevens LA,Behn MD,McGuire JJ,Das SB,Joughin I,Herring T,Shean DE,King MA

更新日期：2015-06-04 00:00:00

abstract：:Two cytosolic fractions (A and B) from Xenopus oocytes are sufficient to support protein import into the nuclei of digitonin-permeabilized cells. Fraction A recognizes the nuclear localization sequence (NLS) and binds the import substrate to the nuclear envelope, whereas fraction B mediates the subsequent passage of t...

journal_title：Nature

authors： Moore MS,Blobel G

更新日期：1993-10-14 00:00:00

abstract：:Since the discovery of superconductivity in the high-transition-temperature (high-T(c)) copper oxides two decades ago, it has been firmly established that the CuO(2) plane is essential for superconductivity and gives rise to a host of other very unusual properties. A new family of superconductors with the general comp...

journal_title：Nature

authors： Chen TY,Tesanovic Z,Liu RH,Chen XH,Chien CL

更新日期：2008-06-26 00:00:00

abstract：:Large low-velocity seismic anomalies have been detected in the Earth's lower mantle beneath Africa and the Pacific Ocean that are not easily explained by temperature variations alone. The African anomaly has been interpreted to be a northwest-southeast-trending structure with a sharp-edged linear, ridge-like morpholog...

journal_title：Nature

authors： McNamara AK,Zhong S

更新日期：2005-10-20 00:00:00

abstract：:The genetic architecture of autism spectrum disorder involves the interplay of common and rare variants and their impact on hundreds of genes. Using exome sequencing, here we show that analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry-matched or parental controls implicates 22 autosomal genes ...

journal_title：Nature

authors： De Rubeis S,He X,Goldberg AP,Poultney CS,Samocha K,Cicek AE,Kou Y,Liu L,Fromer M,Walker S,Singh T,Klei L,Kosmicki J,Shih-Chen F,Aleksic B,Biscaldi M,Bolton PF,Brownfeld JM,Cai J,Campbell NG,Carracedo A,Chahrour

更新日期：2014-11-13 00:00:00

abstract：:How environmental cues regulate adult stem cell and cancer cell activity through surface receptors is poorly understood. Angiopoietin-like proteins (ANGPTLs), a family of seven secreted glycoproteins, are known to support the activity of haematopoietic stem cells (HSCs) in vitro and in vivo. ANGPTLs also have importan...

journal_title：Nature

authors： Zheng J,Umikawa M,Cui C,Li J,Chen X,Zhang C,Huynh H,Kang X,Silvany R,Wan X,Ye J,Cantó AP,Chen SH,Wang HY,Ward ES,Zhang CC

更新日期：2012-05-30 00:00:00

abstract：:A single U leads to G transversion in the 3' consensus sequence AAUAAA of the adenovirus early region 1A gene was constructed and the effect of this mutation on processing of the 3' end of the nuclear early region 1A RNAs was analysed. The results demonstrate that the intact AAUAAA is not required for RNA polyadenylat...

journal_title：Nature

authors： Montell C,Fisher EF,Caruthers MH,Berk AJ

更新日期：1983-10-13 00:00:00

abstract：:Separation of eukaryotic sister chromatids during the cell cycle is timed by the spindle assembly checkpoint (SAC) and ultimately triggered when separase cleaves cohesion-mediating cohesin1-3. Silencing of the SAC during metaphase activates the ubiquitin ligase APC/C (anaphase-promoting complex, also known as the cycl...

journal_title：Nature

authors： Hellmuth S,Gómez-H L,Pendás AM,Stemmann O

更新日期：2020-04-01 00:00:00

abstract：:The crystal structure of a solid controls the interactions between the electronically active units and thus its electronic properties. In the high-temperature superconducting copper oxides, only one spatial arrangement of the electronically active Cu(2+) units-a two-dimensional square lattice-is available to study the...

journal_title：Nature

authors： Ganin AY,Takabayashi Y,Jeglic P,Arcon D,Potocnik A,Baker PJ,Ohishi Y,McDonald MT,Tzirakis MD,McLennan A,Darling GR,Takata M,Rosseinsky MJ,Prassides K

更新日期：2010-07-08 00:00:00

abstract：:Generalization is a cognitive ability that allows similar stimuli along a given dimension to be treated as equivalents. Insects exhibit high levels of visual generalization. Honeybees trained to recognize complex visual stimuli on the basis of a single feature generalize their choice to novel stimuli sharing that comm...

journal_title：Nature

authors： Stach S,Benard J,Giurfa M

更新日期：2004-06-17 00:00:00

abstract：:The four-chambered mammalian heart develops from two fields of cardiac progenitor cells distinguished by their spatiotemporal patterns of differentiation and contributions to the definitive heart. The first heart field differentiates earlier in lateral plate mesoderm, generates the linear heart tube and ultimately giv...

journal_title：Nature

authors： Zhou Y,Cashman TJ,Nevis KR,Obregon P,Carney SA,Liu Y,Gu A,Mosimann C,Sondalle S,Peterson RE,Heideman W,Burns CE,Burns CG

更新日期：2011-05-29 00:00:00

abstract：:Ultraluminous X-ray sources are extragalactic objects located outside the nucleus of the host galaxy with bolometric luminosities exceeding 10(39) erg s(-1). These extreme luminosities-if the emission is isotropic and below the theoretical (Eddington) limit, where the radiation pressure is balanced by the gravitationa...

journal_title：Nature

authors： Farrell SA,Webb NA,Barret D,Godet O,Rodrigues JM

更新日期：2009-07-02 00:00:00

abstract：:Cells are organized on length scales ranging from ångström to micrometres. However, the mechanisms by which ångström-scale molecular properties are translated to micrometre-scale macroscopic properties are not well understood. Here we show that interactions between diverse synthetic, multivalent macromolecules (includ...

journal_title：Nature

authors： Li P,Banjade S,Cheng HC,Kim S,Chen B,Guo L,Llaguno M,Hollingsworth JV,King DS,Banani SF,Russo PS,Jiang QX,Nixon BT,Rosen MK

更新日期：2012-03-07 00:00:00

abstract：:The Earth's convecting upper mantle can be viewed as comprising three main reservoirs, beneath the Pacific, Atlantic and Indian oceans. Because of the uneven global distribution and migration of ridges and subduction zones, the surface area of the Pacific reservoir is at present contracting at about 0.6 km2 x y(r-1), ...

journal_title：Nature

authors： Pearce JA,Leat PT,Barker PF,Millar IL

更新日期：2001-03-22 00:00:00

abstract：:Humoral immune responses to immunization and infection and susceptibilities to antibody-mediated autoimmunity are generally lower in males1-3. However, the mechanisms underlying such sexual dimorphism are not well understood. Here we show that there are intrinsic differences between the B cells that produce germinal c...

journal_title：Nature

authors： Zhao R,Chen X,Ma W,Zhang J,Guo J,Zhong X,Yao J,Sun J,Rubinfien J,Zhou X,Wang J,Qi H

更新日期：2020-01-01 00:00:00

abstract：:To understand the complex physics of a system with strong electron-electron interactions, the ideal is to control and monitor its properties while tuning an external electric field applied to the system (the electric-field effect). Indeed, complete electric-field control of many-body states in strongly correlated elec...

journal_title：Nature

authors： Li LJ,O'Farrell EC,Loh KP,Eda G,Özyilmaz B,Castro Neto AH

更新日期：2016-01-14 00:00:00

abstract：:Long-term potentiation of chemical synapses is closely related to memory and learning. Studies of this process have concentrated on chemically mediated excitatory synapses. By contrast, activity-dependent modification of gap junctions, which also widely exist in higher structures such as hippocampus and neocortex, has...

journal_title：Nature

authors： Yang XD,Korn H,Faber DS

更新日期：1990-12-06 00:00:00

abstract：:Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer and adaptive evolution in experimental organisms. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy could directly bring abou...

journal_title：Nature

authors： Pavelka N,Rancati G,Zhu J,Bradford WD,Saraf A,Florens L,Sanderson BW,Hattem GL,Li R

更新日期：2010-11-11 00:00:00

abstract：:In Fig. 6a of this Article, the two dots corresponding to Cidea and S100b were erroneously moved to the top left of the volcano plot; this figure has been corrected online.An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature

authors： Zeng X,Ye M,Resch JM,Jedrychowski MP,Hu B,Lowell BB,Ginty DD,Spiegelman BM

更新日期：2019-06-01 00:00:00

abstract：:Following the introduction of hydrochlorofluorocarbon (HCFCs) and hydrofluorocarbon (HFCs) gases as replacements for the ozone-destroying chlorofluorocarbons (CFCs), it has been discovered that HCFCs/HFCs can degrade in the atmosphere to produce trifluoroacetic acid, a compound with no known loss mechanisms in the env...

journal_title：Nature

authors： Ellis DA,Mabury SA,Martin JW,Muir DC

更新日期：2001-07-19 00:00:00

abstract：:Large-conductance Ca(2+)-gated K(+) (BK) channels are essential for many biological processes such as smooth muscle contraction and neurotransmitter release. This group of channels can be activated synergistically by both voltage and intracellular Ca(2+), with the large carboxy-terminal intracellular portion being res...

journal_title：Nature

authors： Wu Y,Yang Y,Ye S,Jiang Y

更新日期：2010-07-15 00:00:00

abstract：:Sea ice and dust flux increased greatly in the Southern Ocean during the last glacial period. Palaeorecords provide contradictory evidence about marine productivity in this region, but beyond one glacial cycle, data were sparse. Here we present continuous chemical proxy data spanning the last eight glacial cycles (740...

journal_title：Nature

authors： Wolff EW,Fischer H,Fundel F,Ruth U,Twarloh B,Littot GC,Mulvaney R,Röthlisberger R,de Angelis M,Boutron CF,Hansson M,Jonsell U,Hutterli MA,Lambert F,Kaufmann P,Stauffer B,Stocker TF,Steffensen JP,Bigler M,Siggaard-An

更新日期：2006-03-23 00:00:00

abstract：:Is the big-bang hot, warm or cold? And are galactic masses determined by the interplay of gravitational and strong interactions in the very early universe? ...

journal_title：Nature

authors： Harrison ER

更新日期：1970-10-17 00:00:00

abstract：:Microbialites are organosedimentary structures that can be constructed by a variety of metabolically distinct taxa. Consequently, microbialite structures abound in the fossil record, although the exact nature of the biogeochemical processes that produced them is often unknown. One such class of ancient calcareous stru...

journal_title：Nature

authors： Laval B,Cady SL,Pollack JC,McKay CP,Bird JS,Grotzinger JP,Ford DC,Bohm HR

更新日期：2000-10-05 00:00:00

abstract：:The cortex organizes sensory information to enable discrimination and generalization1-4. As systematic representations of chemical odour space have not yet been described in the olfactory cortex, it remains unclear how odour relationships are encoded to place chemically distinct but similar odours, such as lemon and o...

journal_title：Nature

authors： Pashkovski SL,Iurilli G,Brann D,Chicharro D,Drummey K,Franks KM,Panzeri S,Datta SR

更新日期：2020-07-01 00:00:00

abstract：:The emergence and outgrowth of a population of tumour cells resistant to multiple drugs is a major problem in the chemotherapeutic treatment of cancer. We have used highly drug-resistant cell lines developed in vitro to study the molecular basis of multidrug resistance. In these cell lines high levels of resistance ar...

journal_title：Nature

authors： Gros P,Ben Neriah YB,Croop JM,Housman DE

更新日期：1986-10-23 00:00:00

abstract：:Protein chains coil into alpha-helices and beta-sheet structures. Knowing the timescales and mechanism of formation of these basic structural elements is essential for understanding how proteins fold. For the past 40 years, alpha-helix formation has been extensively investigated in synthetic and natural peptides, incl...

journal_title：Nature

authors： Muñoz V,Thompson PA,Hofrichter J,Eaton WA

更新日期：1997-11-13 00:00:00