Abstract:
:Endocarditis isolates of Enterococcus faecalis produced biofilm significantly more often than nonendocarditis isolates, and 39% of 79 versus 6% of 84 isolates produced strong biofilm (P < 0.0001). esp was not required, but its presence was associated with higher amounts of biofilm (P < 0.001). Mutants disrupted in dltA, efaA, ace, lsa, and six two-component regulatory systems were largely unaltered, while disruptions in epa (encoding enterococcal polysaccharide antigen), atn (encoding an autolysin), gelE (encoding gelatinase), and fsr (encoding the E. faecalis regulator) [corrected] resulted in fewer attached bacteria, as determined using phase-contrast microscopy, and less biofilm (P < 0.0001).
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Mohamed JA,Huang W,Nallapareddy SR,Teng F,Murray BEdoi
10.1128/IAI.72.6.3658-3663.2004keywords:
subject
Has Abstractpub_date
2004-06-01 00:00:00pages
3658-63issue
6eissn
0019-9567issn
1098-5522pii
72/6/3658journal_volume
72pub_type
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