Effect of nitric oxide on the recovery of the hypofunctional periodontal ligament.

Abstract:

:The relationship between occlusal stimuli and a hypofunctional periodontal ligament (PDL) structure has been reported, though changes in occlusal recovery conditions were still unclear. Nitric oxide (NO) produced by NO synthase (NOS) is considered a factor for vascular and immune system control, and it increases according to mechanical stimuli. The objective of this study was to examine the relationship between NOS and occlusal stimuli in PDL by comparing hypofunction with occlusal recovery. The study focused on the expression of endothelial NOS (eNOS) and inducible NOS (iNOS). Their expression significantly decreased in occlusal hypofunction compared with the control group and increased close to normal in an occlusal recovery group. The change in the immunopositive area was more dramatic than the immunopositive cell number. Moreover, the rate of iNOS increase was higher than that of eNOS. This study suggests that NO plays an important role in the recovery of the hypofunctional PDL.

journal_name

J Dent Res

authors

Watarai H,Warita H,Soma K

doi

10.1177/154405910408300413

keywords:

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

338-42

issue

4

eissn

0022-0345

issn

1544-0591

journal_volume

83

pub_type

杂志文章
  • Id1 Expression Level Determines the Differentiation of Human Dental Pulp Stem Cells.

    abstract::TWIST1 plays a crucial role in dentinogenesis, and its activity depends on both a dimerization partner selection and phosphorylation. Other factors, like Id proteins, can affect the availability of dimerization partners for TWIST1, subsequently leading to diverse biological outcomes. The purpose of this study was to e...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034514530164

    authors: Maciejewska I,Sakowicz-Burkiewicz M,Pawelczyk T

    更新日期:2014-06-01 00:00:00

  • A preliminary scanning electron microscope examination of wear striation direction on primate teeth.

    abstract::Wear striations experimentally produced on initially unworn teeth were examined at high magnification using a scanning electron microscope. Certain characteristics of individual wear striations on these teeth indicate the direction of motion that produced them. Other striations on worn teeth of American Indians and th...

    journal_title:Journal of dental research

    pub_type: 历史文章,杂志文章

    doi:10.1177/00220345790580011401

    authors: Ryan AS

    更新日期:1979-01-01 00:00:00

  • H3-HRP analysis of the nerve supply to primate teeth.

    abstract::Sensory, sympathetic and parasympathetic ganglia located in the head and neck of rhesus monkeys were histologically examined after injection of H3-HRP into the right mandibular premolars and molars. The results showed positive labeling of ganglionic cell bodies located in the ipsilateral trigeminal, superior cervical,...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345800590041601

    authors: Chiego DJ Jr,Cox CF,Avery JK

    更新日期:1980-04-01 00:00:00

  • A numerical model of temporomandibular joint loading.

    abstract::A numerical model of the mandible, its articulating surfaces, and the forces exerted by the primary masticatory muscles has been developed for the purpose of investigating loading of the temporomandibular joint. Evidence is presented which shows that the temporomandibular joint. Evidence is presented which shows that ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650080201

    authors: Smith DM,McLachlan KR,McCall WD Jr

    更新日期:1986-08-01 00:00:00

  • The effect of cavity preparation on the metabolism of protein in dentin.

    abstract::Tritiated proline was administered to domestic cats during the development of their permanent dentition. The amount of residual radioactivity was determined autoradiographically at various times after cavity preparation in mature molars and premolars. Two wk after cavity preparation, the amount of radiolabel beneath t...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345820610090101

    authors: Hoppenbrouwers PM,Borggreven JM,Thé GS,Maltha JC

    更新日期:1982-09-01 00:00:00

  • MMPs, IL-1, and TNF are regulated by IL-17 in periodontitis.

    abstract::Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910708600409

    authors: Beklen A,Ainola M,Hukkanen M,Gürgan C,Sorsa T,Konttinen YT

    更新日期:2007-04-01 00:00:00

  • Multiple dendritic cell (DC) subpopulations in human gingiva and association of mature DCs with CD4+ T-cells in situ.

    abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910308200915

    authors: Jotwani R,Cutler CW

    更新日期:2003-09-01 00:00:00

  • Crevice corrosion products of dental amalgam.

    abstract::The objective of this study was to determine the in vitro corrosion products that resulted from crevice corrosion of low- and high-copper dental amalgams. Specimens were potentiostatically polarized in a chloride-containing electrolyte while set against a PTFE surface to form a crevice. After 16 h, corrosion products ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700071301

    authors: Sutow EJ,Jones DW,Hall GC,Owen CG

    更新日期:1991-07-01 00:00:00

  • Biological assessments of experimental cavity cleansers: correlation between in vitro and in vivo studies.

    abstract::Adhesive bonding of resins to dentin surfaces requires the removal of the layer of debris caused by the cutting. Certain isotonic acidic solutions can do this rapidly. Five solutions were evaluated using cell cultures and pulp studies in monkeys. At concentrations above 10%, each solution caused the cultured human epi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345820610081001

    authors: Mjör IA,Hensten-Pettersen A,Bowen RL

    更新日期:1982-08-01 00:00:00

  • Standardization and safety of alveolar bone-derived stem cell isolation.

    abstract::Cell therapies utilizing mesenchymal stem cells (MSCs) could overcome limitations of traditional treatments for reconstructing craniofacial tissues. This large-scale study explored a standardized methodology for the isolation and clinical-scale expansion of alveolar bone marrow-derived MSCs (aBMSCs). We harvested 103 ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513510530

    authors: Mason S,Tarle SA,Osibin W,Kinfu Y,Kaigler D

    更新日期:2014-01-01 00:00:00

  • Storage of human periodontal ligament cells in a combination of different media.

    abstract::Different types of storage media have been studied for use in the replantation of exarticulated teeth. It was found that human periodontal ligament cells survived well in milk. Fifty percent of the cells were viable after 12 hours' storage in milk, while no cells were viable after three hours' storage in saliva. Brief...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345810600111301

    authors: Blomlöf L

    更新日期:1981-11-01 00:00:00

  • Chlorhexide and fluoride in prevention of plaque and caries in hamsters.

    abstract::The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560111401

    authors: Brayer L,Gedalia I,Gover A

    更新日期:1977-11-01 00:00:00

  • Bone regeneration in defects compromised by radiotherapy.

    abstract::Because bone reconstruction in irradiated sites is less than ideal, we applied a regenerative gene therapy method in which a cell-signaling virus was localized to biomaterial scaffolds to regenerate wounds compromised by radiation therapy. Critical-sized defects were created in rat calvariae previously treated with ra...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034509352151

    authors: Hu WW,Ward BB,Wang Z,Krebsbach PH

    更新日期:2010-01-01 00:00:00

  • Etching patterns of Co-Cr alloys for bonded cast restorations.

    abstract::Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345870660091301

    authors: Ekstrand K,Ruyter IE

    更新日期:1987-09-01 00:00:00

  • Late elongation of the cranial base.

    abstract::A single logistic curve was fitted to serial data for three cranial base lengths (S-N, Ba-N, and Ba-S) in 33 boys and 26 girls. Elongation during pubescence plus adolescence is greater in boys than girls for each length. The maximum rate of pubescent elongation occurs earliest in Ba-N. There are no consistent sex diff...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560071501

    authors: Roche AF,Lewis AB,Wainer H,McCartin R

    更新日期:1977-07-01 00:00:00

  • Distribution of chondroitin sulfate and dermatan sulfate in normal and inflamed human gingivae.

    abstract::The effect of inflammation on the distribution of chondroitin sulfate and dermatan sulfate proteoglycans was assessed after normal and inflamed human gingivae were stained with monoclonal antibodies against these extracellular matrix macromolecules. The tissues were obtained following periodontal surgery and reacted w...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345920710090801

    authors: Bartold PM

    更新日期:1992-09-01 00:00:00

  • CD73 Controls Extracellular Adenosine Generation in the Trigeminal Nociceptive Nerves.

    abstract::Purinergic signaling is involved in pain generation and modulation in the nociceptive sensory nervous system. Adenosine triphosphate (ATP) induces pain via activation of ionotropic P2X receptors while adenosine mediates analgesia via activation of metabotropic P1 receptors. These purinergic signaling are determined by...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517692953

    authors: Liu X,Ma L,Zhang S,Ren Y,Dirksen RT

    更新日期:2017-06-01 00:00:00

  • Caregivers' health literacy and their young children's oral-health-related expenditures.

    abstract::Caregivers' health literacy has emerged as an important determinant of young children's health care and outcomes. We examined the hypothesis that caregivers' health literacy influences children's oral-health-care-related expenditures. This was a prospective cohort study of 1,132 child/caregiver dyads (children's mean ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513484335

    authors: Vann WF Jr,Divaris K,Gizlice Z,Baker AD,Lee JY

    更新日期:2013-07-01 00:00:00

  • Estimated drinking water fluoride exposure and risk of hip fracture: a cohort study.

    abstract::The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513506443

    authors: Näsman P,Ekstrand J,Granath F,Ekbom A,Fored CM

    更新日期:2013-11-01 00:00:00

  • Nine Novel PAX9 Mutations and a Distinct Tooth Agenesis Genotype-Phenotype.

    abstract::Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517729322

    authors: Wong SW,Han D,Zhang H,Liu Y,Zhang X,Miao MZ,Wang Y,Zhao N,Zeng L,Bai B,Wang YX,Liu H,Frazier-Bowers SA,Feng H

    更新日期:2018-02-01 00:00:00

  • Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases.

    abstract::Iodoacetate at 10(-3) M and 10(-4) M concentrations was found to strongly inhibit incorporation of both 14C-choline and 3H-inositol into phospholipids of calvaria from newborn rats; it had somewhat less effect on ethanolamine incorporation and almost no effect on serine incorporation. Similar though less dramatic resu...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345750540050101

    authors: Dirksen TR,Schuster GS,McKinney R,Bustos SE

    更新日期:1975-09-01 00:00:00

  • Radiographic secondary caries prevalence in teeth with clinically defective restorations.

    abstract::Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345930720121301

    authors: Hewlett ER,Atchison KA,White SC,Flack V

    更新日期:1993-12-01 00:00:00

  • A longitudinal evaluation of fissure sealants applied in dental practices.

    abstract::Sealants are highly effective in preventing dental caries in the pits and fissures of teeth when applied by trained operators in clinical trials and public health programs. The effectiveness of fissure sealants when applied in dental practices is still not known. The purpose of this longitudinal study was to evaluate ...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章

    doi:10.1177/00220345950740091301

    authors: Ismail AI,Gagnon P

    更新日期:1995-09-01 00:00:00

  • Craniofacial and TMJ effects after glutamate and TRH microsphere implantation in proximity to trigeminal motoneurons of growing rats.

    abstract::The sequelae of sustained, in vivo delivery of two important neurotransmitter substances, glutamate and thyrotropin-releasing hormone (TRH), upon craniofacial growth and development have previously not been investigated. Our purpose was to document and compare the relative effects of glutamate and TRH microspheres ste...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345970760080601

    authors: Byrd KE,Sukay MJ,Dieterle MW,Yang L,Marting TC,Teomim D,Domb AJ

    更新日期:1997-08-01 00:00:00

  • Med23 Regulates Sox9 Expression during Craniofacial Development.

    abstract::The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034520969109

    authors: Dash S,Bhatt S,Falcon KT,Sandell LL,Trainor PA

    更新日期:2020-11-06 00:00:00

  • The presence of fucosyltransferases with different substrate specificity in human parotid saliva.

    abstract::Using glycoproteins and milk oligosaccharides as substrate acceptors, we demonstrated at least two fucosyltransferases in human parotid saliva. One enzyme transferred L-fucose from GDP-fucose to the C-3 position of N-acetylglucosamine or glucose residue of oligosaccharide chains, and the other transferred to the C-4 p...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345830620070701

    authors: Tamagawa H,Inoshita E,Shibata S,Shizukuishi S,Tsunemitsu A

    更新日期:1983-07-01 00:00:00

  • Polynomial and catenary curve fits to human dental arches.

    abstract::Polynomial and catenary equations were fit by least square error methods to the dentitions of seven children with "normal" occlusion. Mean and mean square error were then used to analyze accuracy of curve fits and asymmetries of arches. A lack of congruency for the "lines of occlusion" common to the maxilla and mandib...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345750540060501

    authors: Pepe SH

    更新日期:1975-11-01 00:00:00

  • The measurement of the effect of toothbrushes on soft tissue abrasion.

    abstract::The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of s...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560070301

    authors: Alexander JF,Saffir AJ,Gold W

    更新日期:1977-07-01 00:00:00

  • Genetics of human taste perception.

    abstract::Genetic approaches are rapidly yielding new information about our sense of taste. This information comes from both molecular studies of genes encoding taste receptors and other taste-signaling components, and from studies of inherited variation in taste abilities. Our understanding of bitter taste has advanced by comb...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/154405910408300603

    authors: Kim UK,Breslin PA,Reed D,Drayna D

    更新日期:2004-06-01 00:00:00

  • Radiopaque Tagging Masks Caries Lesions following Incomplete Excavation in vitro.

    abstract::One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034514531291

    authors: Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

    更新日期:2014-06-01 00:00:00