Absence of dystrophin in two patients with Becker type Xp21 muscular dystrophy.

abstract：:Male and female eels were hypophysectomized by a buccal approach and examined either 2 and 7 weeks (males) or 4 and 5 months (females) later. Intact and sham-operated eels served as controls. Fish were killed by decapitation, and the brains fixed in sublimated Bouin-Hollande solution and embedded in paraffin wax. Fron...

journal_title：Neuroscience letters

authors： Olivereau M,Olivereau J

更新日期：1988-09-12 00:00:00

abstract：:Substance P caused a depolarization of cultured spinal neurones which was often accompanied by a decrease in membrane conductance. The peptide usually had no effect on the membrane potential and resistance of glial cells. In contrast to the depolarization by glutamate, which is associated with an influx of Na+ and an ...

journal_title：Neuroscience letters

authors： Hösli L,Hösli E,Zehntner C,Landolt H

更新日期：1981-07-02 00:00:00

abstract：:Event-related potentials were recorded from sleeping newborns to compare amplitudes and latencies of mismatch negativity (MMN) and late discriminative negativity (LDN) in active and quiet sleep stages. MMN and LDN were obtained in response to changes in semi-synthesized vowels from 20 healthy newborn infants. MMN and ...

journal_title：Neuroscience letters

authors： Martynova O,Kirjavainen J,Cheour M

更新日期：2003-04-10 00:00:00

abstract：:Two opposing hypotheses on the homology of the avian brain suggest that the dorsal ventricular ridge of birds is comparable in certain respects either to the neocortex or to the claustroamygdalar complex of mammals. To help resolve this issue, we examined in adult chicken brains the gene expression of RORβ mRNA, a sel...

journal_title：Neuroscience letters

authors： Atoji Y,Karim MR

更新日期：2012-07-19 00:00:00

abstract：:Application of NMDA, or agents releasing nitric oxide (NO), onto the dendrites of hippocampal granule cells increased the levels of the mRNA encoding MAP2, a cytoskeletal component induced during periods of neurite outgrowth. Furthermore, local increases in the hybridisation signal in the molecular layer, representing...

journal_title：Neuroscience letters

authors： Johnston HM,Morris BJ

更新日期：1994-08-15 00:00:00

abstract：:Cholinergic influences on attention are well documented and recent evidence indicates that genetic variation in the alpha4beta2 nicotinic receptor affects attentional networks of the brain. Several behavioral and electrophysiological studies have shown that a common polymorphism in the CHRNA4 gene (rs1044396) affects ...

journal_title：Neuroscience letters

authors： Reinvang I,Lundervold AJ,Rootwelt H,Wehling E,Espeseth T

更新日期：2009-04-10 00:00:00

abstract：:The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2. It was observed that nifedipine at the concentrat...

journal_title：Neuroscience letters

authors： Li SN,Bräter M,Andreas K

更新日期：1997-07-18 00:00:00

abstract：:Ethanol withdrawal is a serious clinical problem owing in part to over stimulation of ionotropic glutamate receptors in the brain and is linked to elevated oxidative damage. In this study, we tested the hypothesis that lipid peroxidation is elevated in the brain tissue of rats fed an ethanol-containing diet for 6 week...

journal_title：Neuroscience letters

authors： Milne GL,Morrow JD,Picklo MJ Sr

更新日期：2006-09-25 00:00:00

abstract：:FOXP2, the first gene known to be involved in the development of speech and language, can be considered to be, a priori, a candidate gene in schizophrenia, given the mounting evidence that the underlying core deficit in this disease could be a failure of structures relevant to normal language processing. To investigat...

journal_title：Neuroscience letters

authors： Španiel F,Horáček J,Tintěra J,Ibrahim I,Novák T,Čermák J,Klírová M,Höschl C

更新日期：2011-04-15 00:00:00

abstract：:Displaced ganglion cells were identified in the carp retina by the retrograde axonal transport of horseradish peroxidase injected into the optic tectum. Cells in the ganglion cell layer were all labelled, while in the amacrine cell layer only 1/4000 cells were labelled. Because of such low population, it is unlikely t...

journal_title：Neuroscience letters

authors： Tachibana M

更新日期：1978-09-01 00:00:00

abstract：:We examined the suggestion that some of the processes subserving learning through action-observation and motor-execution are different because sensory motor reafference is not available while the limb is at rest in the former condition. We confirmed the action-observation and motor-execution groups learned equally the...

journal_title：Neuroscience letters

authors： Hayes SJ,Andrew M,Elliott D,Roberts JW,Bennett SJ

更新日期：2012-01-11 00:00:00

abstract：:The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 mum thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of th...

journal_title：Neuroscience letters

authors： Mosko SS,Jacobs BL

更新日期：1976-06-01 00:00:00

abstract：:Edaravone, an electron spin trapper with radical scavenging activity, has been shown to be effective in reducing infarct volume in humans following ischemic stroke. However, concerns of edaravone-induced renal toxicity have limited its clinical adoption. Previous work has demonstrated that edaravone produced significa...

journal_title：Neuroscience letters

authors： Connell BJ,Saleh MC,Kucukkaya I,Abd-El-Aziz AS,Khan BV,Saleh TM

更新日期：2014-02-21 00:00:00

abstract：:Melatonin is a tryptophan metabolite synthesized by the pineal gland. Recent research showed that melatonin has a protective effect in Alzheimer's disease (AD). However, its exact mechanism is still unclear. This study was designed to investigate the effects of long-term oral melatonin on spatial learning and memory, ...

journal_title：Neuroscience letters

authors： Sun C,Qiu X,Wang Y,Liu J,Li Q,Jiang H,Li S,Song C

更新日期：2020-09-14 00:00:00

abstract：:Moral sense is defined as a feeling of fairness or unfairness of an action that knowingly causes harm to people other than the subject. It is crucial in determining human behavior and becomes pivotal in operational environments. Here we assessed whether professional daily life experience in an operational environment ...

journal_title：Neuroscience letters

authors： Boccia M,Verde P,Angelino G,Carrozzo P,Vecchi D,Piccardi L,Colangeli S,Cordellieri P,Ferlazzo F,Giannini AM

更新日期：2017-07-27 00:00:00

abstract：:Adenosine and AMP (5'-adenosine monophosphate) applied by microiontophoresis produced depression of neuronal firing rates in cerebral cortex. A number of antidepressant drugs including examples which are known not to affect noradrenaline uptake systems, potentiated the depressant purine effects. Noradrenaline response...

journal_title：Neuroscience letters

authors： Stone TW,Taylor DA

更新日期：1979-01-01 00:00:00

abstract：:In vivo differential pulse voltammetry with carbon fiber electrodes was used to monitor extracellular 5-hydroxyindoleacetic acid (5-HIAA) levels in a serotonergic denervated target area, the striatum, before and after transplantation of mesencephalic raphé nuclei into the lateral ventricle in the rat. The amplitude of...

journal_title：Neuroscience letters

authors： McRae-Degueurce A,Serrano A,Sandillon F,Privat A,Scatton B

更新日期：1984-07-27 00:00:00

abstract：:The primary component of amyloid deposits found in the brains of patients with Alzheimer's disease is the beta-amyloid protein, a derivative of a much larger precursor protein (beta PP). We have previously reported that overexpression of carboxyl (COOH)-terminal fragments of beta PP from an integrated DNA construct le...

journal_title：Neuroscience letters

authors： Fukuchi K,Sopher B,Furlong CE,Smith AC,Dang N,Martin GM

更新日期：1993-05-14 00:00:00

abstract：:[35S]Methionine was injected into the mediodorsal nucleus of the thalamus of 5 adult tree shrews (Tupaia belangeri) and into the medioventral thalamic nucleus in another tree shrew. Three animals survived for 44 h and three others for two weeks (including the animal with the injection in the medioventral nucleus). Con...

journal_title：Neuroscience letters

authors： Divac I,Passingham RE

更新日期：1980-08-01 00:00:00

abstract：:Projections of neurones in Forel's field H (FFH) to the upper cervical cord and to the lower brainstem were demonstrated by retrograde labelling of the neurones with horseradish peroxidase (HRP). Systematic threshold mapping for evoking antidromic spikes of FFH neurones revealed that they projected to the neck motor n...

journal_title：Neuroscience letters

authors： Isa T,Itouji T,Sasaki S

更新日期：1988-07-19 00:00:00

abstract：:To investigate whether there is a descending contribution to the spinal 5-hydroxytryptamine (5-HT) innervation in the lamprey, a primitive vertebrate, a study using retrograde transport of the fluorescent tracer Fast blue combined with 5-HT immunohistochemistry was conducted. Two to 4 weeks after an injection of Fast ...

journal_title：Neuroscience letters

authors： Brodin L,Buchanan JT,Hökfelt T,Grillner S,Verhofstad AA

更新日期：1986-06-06 00:00:00

abstract：:In this study we evaluated oxidative stress (lipid peroxidation and protein oxidation) and thiol redox state [TRS: glutathione (GSH), glutathione disulfide (GSSG), cysteine (CSH), protein (P) thiols (PSH) and protein and non-protein (NP) mixed/symmetric disulfides (PSSR, NPSSR, NPSSC, PSSP)] in hippocampus after penty...

journal_title：Neuroscience letters

authors： Patsoukis N,Zervoudakis G,Panagopoulos NT,Georgiou CD,Angelatou F,Matsokis NA

更新日期：2004-03-04 00:00:00

abstract：:Deep brain stimulation (DBS) is now emerging as a new option for treating intractable epilepsy. Cumulative studies suggest that the mediodorsal thalamic nucleus (MD) is involved in limbic seizure activity. This study aims to investigate whether DBS of the MD can protect against seizures induced by amygdaloid kindling....

journal_title：Neuroscience letters

authors： Wang S,Wu DC,Fan XN,Zhu MZ,Hu QY,Zhou D,Ding MP,Chen Z

更新日期：2010-09-06 00:00:00

abstract：:Previous studies have demonstrated that both visual and proprioceptive feedback influence motor control. The relative contributions of these sensory modalities to the on-line computation of body position--that is, the body schema--remain unclear. We report a study designed to explore the roles of vision and propriocep...

journal_title：Neuroscience letters

authors： Shenton JT,Schwoebel J,Coslett HB

更新日期：2004-11-03 00:00:00

abstract：:Rho kinase (ROCK) regulates the functions of several target proteins via its kinase activity. Therefore, ROCK activity inhibition may provide new possibilities of controlling the in vitro neuronal differentiation of embryonic stem (ES) cells. When we investigated the effects of the ROCK inhibitor Y-27632 on ES cell di...

journal_title：Neuroscience letters

authors： Kamishibahara Y,Kawaguchi H,Shimizu N

更新日期：2016-02-26 00:00:00

abstract：:Imaging studies indicate smaller orbitofrontal cortex (OFC) volume in mood disorder patients compared with healthy subjects. We sought to determine whether child and adolescent patients with bipolar disorder have smaller OFC volumes than healthy controls. Fourteen children and adolescents meeting DSM-IV criteria for b...

journal_title：Neuroscience letters

authors： Najt P,Nicoletti M,Chen HH,Hatch JP,Caetano SC,Sassi RB,Axelson D,Brambilla P,Keshavan MS,Ryan ND,Birmaher B,Soares JC

更新日期：2007-02-21 00:00:00

abstract：:Painful vincristine (VCR) neuropathy is a frequent and dose-limiting problem in cancer treatment. Here, we investigated how pain behavior is modulated in mice lacking the serotonin transporter (5-HTT-/- mice) after inducing neuropathy by intraperitoneal injections of VCR. We used standard tests for evoked pain, high p...

journal_title：Neuroscience letters

authors： Hansen N,Uçeyler N,Palm F,Zelenka M,Biko L,Lesch KP,Gerlach M,Sommer C

更新日期：2011-05-16 00:00:00

abstract：:A retrograde tracer, Diamidino yellow, was injected into the hindlimb region of the supplementary motor area after intracortical microstimulation mapping in the Japanese monkey. As a result, a cluster of retrogradely labeled neurons was found in the caudal bank of the arcuate sulcus, which corresponds to the ventral p...

journal_title：Neuroscience letters

authors： Tokuno H,Inase M

更新日期：1994-04-25 00:00:00

abstract：:After hypoxic-ischemic insult iron deposited in the brain catalyzes formation of reactive oxygen species. Newborn rats, showing reduced physiological body temperature and their hyperthermic counterparts injected with deferoxamine (DF), a chelator of iron, are protected both against iron-mediated neurotoxicity and agai...

journal_title：Neuroscience letters

authors： Kletkiewicz H,Nowakowska A,Siejka A,Mila-Kierzenkowska C,Woźniak A,Caputa M,Rogalska J

更新日期：2016-08-15 00:00:00

abstract：:In 8 subjects the spontaneous termination of sleep was determined after repetitive exposure to either bright or dim light, between 6.00 and 9.00 h, on 3 days preceding sleep assessment. Sleep duration was significantly shorter following bright light than following dim light. During sleep the time course of EEG energy ...

journal_title：Neuroscience letters

authors： Dijk DJ,Visscher CA,Bloem GM,Beersma DG,Daan S

更新日期：1987-01-14 00:00:00