Abstract:
:Plasmid R1 is a low-copy-number plasmid that is present at a level of about four or five copies per average cell. The copy number is controlled posttranscriptionally at the level of synthesis of the rate-limiting initiator protein RepA. In addition to this, R1 has an auxiliary system that derepresses a second promoter at low copy numbers, leading to increased repA mRNA synthesis. This promoter is normally switched off by a constitutively synthesized plasmid-encoded repressor protein, CopB; in cells with low copy numbers, the concentration of CopB is low and the promoter is derepressed. Here we show that the rate of loss of a Par(+) derivative of the basic replicon of R1 increased about sevenfold when the cells contained a high concentration of the CopB protein formed from a compatible plasmid.
journal_name
J Bacterioljournal_title
Journal of bacteriologyauthors
Olsson JA,Paulsson J,Nordström Kdoi
10.1128/jb.186.1.207-211.2004keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
207-11issue
1eissn
0021-9193issn
1098-5530journal_volume
186pub_type
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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journal_title:Journal of bacteriology
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journal_title:Journal of bacteriology
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pub_type: 杂志文章
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更新日期:1986-02-01 00:00:00
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journal_title:Journal of bacteriology
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更新日期:1963-11-01 00:00:00
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journal_title:Journal of bacteriology
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更新日期:2001-02-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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journal_title:Journal of bacteriology
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doi:10.1128/JB.147.3.827-835.1981
更新日期:1981-09-01 00:00:00
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journal_title:Journal of bacteriology
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更新日期:2013-10-01 00:00:00
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更新日期:1974-06-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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更新日期:1970-08-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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更新日期:2002-07-01 00:00:00
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journal_title:Journal of bacteriology
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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更新日期:2012-10-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.116.2.673-684.1973
更新日期:1973-11-01 00:00:00
abstract::Holwerda, Jack (Michigan Department of Health, Grand Rapids) and Grace Eldering. Culture and fluorescent-antibody methods in diagnosis of whooping cough. J. Bacteriol. 86:449-451. 1963.-Nasopharyngeal swabs from 517 suspected whooping-cough patients were examined by culture and by fluorescent-antibody (FA) staining pr...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.86.3.449-451.1963
更新日期:1963-09-01 00:00:00
abstract::Archaea are abundant and drive critical microbial processes in the Earth's cold biosphere. Despite this, not enough is known about the molecular mechanisms of cold adaptation and no biochemical studies have been performed on stenopsychrophilic archaea (e.g., Methanogenium frigidum). This study examined the structural ...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.00395-07
更新日期:2007-08-01 00:00:00