The ability to replicate in macrophages is conserved between Yersinia pestis and Yersinia pseudotuberculosis.

abstract：:Extracytoplasmic proteins were released from Serpulina (Treponema) hyodysenteriae (strain B204) by treatment of whole cells with a nonionic detergent (Tween 20). Centrifugation of the Tween 20-released proteins at 100,000 x g sedimented 10 major extracytoplasmic proteins with approximate molecular masses of 44, 43.5, ...

journal_title：Infection and immunity

authors： Gabe JD,Chang RJ,Slomiany R,Andrews WH,McCaman MT

更新日期：1995-01-01 00:00:00

abstract：:Bordetella pertussis is the causative agent of whooping cough, a potentially lethal respiratory disease in children. In immunocompetent individuals, B. pertussis infection elicits an effective adaptive immune response driven by activated CD4(+) T cells. However, live B. pertussis persists in the host for 3 to 4 weeks ...

journal_title：Infection and immunity

authors： Shumilla JA,Lacaille V,Hornell TM,Huang J,Narasimhan S,Relman DA,Mellins ED

更新日期：2004-03-01 00:00:00

abstract：:Most vaccines are still given parenterally. Mucosal vaccination would offer different advantages over parenteral immunization, including blocking of the pathogens at the portal of entry. In this paper, nontoxic Escherichia coli heat-labile enterotoxin (LT) mutants and Supramolecular Biovector systems (SMBV) were evalu...

journal_title：Infection and immunity

authors： Baudner BC,Balland O,Giuliani MM,Von Hoegen P,Rappuoli R,Betbeder D,Del Giudice G

更新日期：2002-09-01 00:00:00

abstract：:Legionella pneumophila is a facultative intracellular bacterium which readily grows in cultures of guinea pig and human mononuclear phagocytes. In this report, we demonstrate that the Legionella sp. also grows in thioglycolate-elicited macrophages obtained from A/J mice but not in cells from other mouse strains tested...

journal_title：Infection and immunity

authors： Yamamoto Y,Klein TW,Newton CA,Widen R,Friedman H

更新日期：1988-02-01 00:00:00

abstract：:Theileria parasites infect and transform bovine leukocytes. We have analyzed laboratory-established Theileria sp.-infected leukocyte lines and observed that transformed macrophages express CD5. Low-level expression of CD5 by macrophages was further confirmed on three independent Theileria annulata clinical isolates fr...

journal_title：Infection and immunity

authors： Moreau MF,Thibaud JL,Miled LB,Chaussepied M,Baumgartner M,Davis WC,Minoprio P,Langsley G

更新日期：1999-12-01 00:00:00

abstract：:Female C57BL/6J mice were infected with Trypanosoma cruzi and subsequently given macrophages or lymphocytes from syngeneic donors which had recovered from the acute infection. Mice which received immune peritoneal macrophages, splenic lymphocytes, or lymph node lymphocytes developed lower mean parasitemias and cumulat...

journal_title：Infection and immunity

authors： Burgess DE,Hanson WL

更新日期：1979-09-01 00:00:00

abstract：:Histoplasma capsulatum induces a cell-mediated immune response in the lungs and lymphoid organs of mammals. In this study, we analyzed the progression of the cytokine and inflammatory reactions in the lungs of mice infected intranasally with H. capsulatum. We measured cytokine mRNA levels and determined the inflammato...

journal_title：Infection and immunity

authors： Cain JA,Deepe GS Jr

更新日期：1998-04-01 00:00:00

abstract：:Surface layer proteins (SLPs) are essential for induction of abortion by Campylobacter fetus subsp. fetus in experimentally challenged ewes. These proteins are encoded by multiple sap genes and vary in size and antigenicity. The role of SLP antigenic variation during experimental ovine infection was investigated. Foll...

journal_title：Infection and immunity

authors： Grogono-Thomas R,Blaser MJ,Ahmadi M,Newell DG

更新日期：2003-01-01 00:00:00

abstract：:The appearance of lymphotoxin in the culture fluid of phytohemagglutinin (PHA)-stimulated mouse spleen cells required two cell fractions that were separated by adherence to plastic. Upon stimulation with PHA, neither cell fraction alone produced significant amounts of lymphotoxin; however, when the cell fractions were...

journal_title：Infection and immunity

authors： Aksamit RR,Leonard EJ

更新日期：1982-06-01 00:00:00

abstract：:Serum antibody responses to toxic shock syndrome (TSS) toxin 1 (TSST-1) and staphylococcal enterotoxins A, B, and C were determined by western blot (immunoblot) analysis of acute- and convalescent-phase paired sera from 18 TSS- and 31 non-TSS-associated Staphylococcus aureus infections. Compared with non-TSS cases, se...

journal_title：Infection and immunity

authors： Whiting JL,Rosten PM,Chow AW

更新日期：1989-01-01 00:00:00

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00

abstract：:Infection with highly pathogenic Streptococcus suis can cause septic shock, which is characterized by high levels of inflammatory cytokines and a high mortality rate. Our previous study indicated that TREM-1 (triggering receptor expressed on myeloid cells 1) was upregulated in swine spleen cells in response to S. suis...

journal_title：Infection and immunity

authors： Yang C,Chen B,Zhao J,Lin L,Han L,Pan S,Fu L,Jin M,Chen H,Zhang A

更新日期：2015-08-01 00:00:00

abstract：:Inactivation of sortase gene srtA in Streptococcus pneumoniae strain R6 caused the release of beta-galactosidase and neuraminidase A (NanA) from the cell wall into the surrounding medium. Both of these surface proteins contain the LPXTG motif in the C-terminal domain. Complementation with plasmid-borne srtA reversed p...

journal_title：Infection and immunity

authors： Kharat AS,Tomasz A

更新日期：2003-05-01 00:00:00

abstract：:Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1), a variant parasite protein expressed on the surface of IE and encoded by var gene...

journal_title：Infection and immunity

authors： Elliott SR,Duffy MF,Byrne TJ,Beeson JG,Mann EJ,Wilson DW,Rogerson SJ,Brown GV

更新日期：2005-05-01 00:00:00

abstract：:Myeloid differentiation protein 88 (MyD88) is a general adaptor for the signaling cascade through receptors of the Toll/IL-1R family. When infected with Leishmania major parasites, MyD88-deficient mice displayed a dramatically enhanced parasite burden in their tissues similar to that found in susceptible BALB/c mice. ...

journal_title：Infection and immunity

authors： Debus A,Gläsner J,Röllinghoff M,Gessner A

更新日期：2003-12-01 00:00:00

abstract：:Bovine digital dermatitis (BDD), an infectious disease of the bovine foot with a predominant treponemal etiology, is a leading cause of lameness in dairy and beef herds worldwide. BDD is poorly responsive to antimicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgently soug...

journal_title：Infection and immunity

authors： Staton GJ,Carter SD,Ainsworth S,Mullin J,Smith RF,Evans NJ

更新日期：2020-04-20 00:00:00

abstract：:The susceptibility of HeLa cells to Mycoplasma pneumoniae-induced injury was examined. Infections were initiated with relatively low mycoplasma doses, carried out in a culture medium incapable of supporting M. pneumoniae replication in the absence of host cells, and monitored for up to 10 days. Under these conditions,...

journal_title：Infection and immunity

authors： Krause DC,Chen YY

更新日期：1988-08-01 00:00:00

abstract：:The hemolysins of Serpulina hyodysenteriae are active at 27 to 40 degrees C and pH 3 to 9 and are unaffected by enzymatic inhibitors. Pore formation was demonstrated by the inhibition of hemolysis with molecules of 2.0 to 2.3 nm in diameter and the release of 86rubidium from erythrocytes without hemoglobin release aft...

journal_title：Infection and immunity

authors： Hyatt DR,Joens LA

更新日期：1997-11-01 00:00:00

abstract：:Chagas' disease is a chronic infection caused by Trypanosoma cruzi and represents an important public health burden in Latin America. Frequently the disease evolves undetectable for decades, while in a significant fraction of the affected individuals it culminates in death by heart failure. Here, we describe a novel m...

journal_title：Infection and immunity

authors： Marinho CR,Bucci DZ,Dagli ML,Bastos KR,Grisotto MG,Sardinha LR,Baptista CR,Gonçalves CP,Lima MR,Alvarez JM

更新日期：2004-04-01 00:00:00

abstract：:Akabane virus (a Bunyavirus) has been associated with epizootics of congenital deformities in cattle, sheep, and goats. Experimental studies using mouse-adapted virus inoculated intravenously into pregnant sheep gave an inapparent infection. Neutralizing antibodies were detected on day 5, and peaks in the titer were s...

journal_title：Infection and immunity

authors： Parsonson IM,Della-Porta AJ,Snowdon WA

更新日期：1977-01-01 00:00:00

abstract：:Bordetella pertussis adenylate cyclase-hemolysin (AC-Hly), encoded by the cyaA gene, belongs to the RTX family of toxins with extensive glycine-rich repeats in the carboxy-terminal portion. AC-Hly possesses both adenylate cyclase toxic and hemolytic activities that depend on a posttranslational modification mediated b...

journal_title：Infection and immunity

authors： Betsou F,Sebo P,Guiso N

更新日期：1993-09-01 00:00:00

abstract：:Protozoan parasites of the genus Leishmania exist as obligatory intracellular amastigotes and invade macrophages and Langerhans cells, the dendritic cells of the skin. Langerhans cells are much more efficient in presenting Leishmania major antigen to T cells than macrophages are and have the unique ability to retain p...

journal_title：Infection and immunity

authors： Flohé S,Lang T,Moll H

更新日期：1997-08-01 00:00:00

abstract：:Ring-necked pheasant virus, an avian leukosis virus, when injected into 10-day old chick embryos, caused angiosarcomas in the lungs of infected chickens within a short time. Angiosarcomas appeared as localized foci of proliferating cells in the lungs as early as 2 weeks posthatch, and by 6 weeks, the lungs of the infe...

journal_title：Infection and immunity

authors： Carter JK,Proctor SJ,Smith RE

更新日期：1983-04-01 00:00:00

abstract：:In vivo expression of pili by Escherichia coli in the urine of 41 adults with lower urinary tract infections was analyzed by immunostaining with polyclonal antiserum to type 1 and P pili. Type 1 pili were detected in 31 of 41 urine specimens, while P pili were detected in 6 of 18 specimens. The piliation status of bac...

journal_title：Infection and immunity

authors： Kisielius PV,Schwan WR,Amundsen SK,Duncan JL,Schaeffer AJ

更新日期：1989-06-01 00:00:00

abstract：:Onchocerca volvulus, a human parasitic nematode, is the third leading cause of preventable blindness worldwide. This study describes the molecular cloning of a novel superoxide dismutase (SOD) from the parasite. This putative O. volvulus extracellular SOD (OvEcSOD) is 628 nucleotides (nt) long, including a 22-nt 5' sp...

journal_title：Infection and immunity

authors： James ER,McLean DC Jr,Perler F

更新日期：1994-02-01 00:00:00

abstract：:Various pathogenic bacteria with the capacity to live within eukaryotic cells activate an apoptotic program in infected host cells. Induction of apoptosis by Listeria monocytogenes in murine dendritic cells and hepatocytes has been described. Here we address the questions of whether and how the pathogen kills macropha...

journal_title：Infection and immunity

authors： Barsig J,Kaufmann SH

更新日期：1997-10-01 00:00:00

abstract：:Specific stimulation of T cells by phytohemagglutinin and Lens culinaris lectin was inhibited by a soluble factor(s) secreted by normal adherent cells stimulated with culture filtrate protein extract (CFPE) derived from bacterial cultures of Mycobacterium tuberculosis H37Ra (avirulent) and H37Rv (virulent). The induct...

journal_title：Infection and immunity

authors： Parra C,Montaño LF,Huesca M,Rayón I,Willms K,Goodsaid F

更新日期：1986-04-01 00:00:00

abstract：:The goal of this study was to determine the roles of eosinophils and neutrophils in innate and adaptive protective immunity to larval Strongyloides stercoralis in mice. The experimental approach used was to treat mice with an anti-CCR3 monoclonal antibody to eliminate eosinophils or to use CXCR2-/- mice, which have a ...

journal_title：Infection and immunity

authors： Galioto AM,Hess JA,Nolan TJ,Schad GA,Lee JJ,Abraham D

更新日期：2006-10-01 00:00:00

abstract：:Three dominant proteins (41, 48, and 49 kDa) were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in purified preparations of the extracellular aspartyl proteinase (AP) of Candida albicans. All three proteins bound to the specific carboxyl proteinase ligand, pepstatin A, and were assoc...

journal_title：Infection and immunity

authors： Morrison CJ,Hurst SF,Bragg SL,Kuykendall RJ,Diaz H,Pohl J,Reiss E

更新日期：1993-05-01 00:00:00

abstract：:Infection of L cells with Chlamydia psittaci inhibited the burst of deoxyribonucleic acid synthesis that occurs when the host cells are released from a double thymidine block. ...

journal_title：Infection and immunity

authors： Tribby II,Moulder JW

更新日期：1971-02-01 00:00:00