Theileria annulata in CD5(+) macrophages and B1 B cells.

abstract：:Macrophages encode several Toll-like receptors (TLRs) that recognize bacterial components, such as lipoproteins (TLR2) or lipopolysaccharides (TLR4), and activate multiple signaling pathways. Activation of transcription factor NF-kappaB by TLR2 or TLR4 signaling promotes proinflammatory and cell survival responses. Al...

journal_title：Infection and immunity

authors： Zhang Y,Bliska JB

更新日期：2003-03-01 00:00:00

abstract：:Polymorphonuclear leukocytes (PMN) isolated from human blood were exposed to various levels of hydrogen sulfide. The effect on respiratory burst, myeloperoxidase activity, and capacity to phagocytose and kill bacteria were studied. A 1-h exposure of the PMN to 1 mM sulfide did not decrease their myeloperoxidase activi...

journal_title：Infection and immunity

authors： Claesson R,Granlund-Edstedt M,Persson S,Carlsson J

更新日期：1989-09-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae serotype 7 strains are shown to spontaneously lose cytolytic activity with a frequency of approximately 10(-4). The phenotypic change is associated with the loss of approximately 8.5 kbp of chromosomal DNA. A genomic fragment encoding the cytolysin and its flanking sequences was cloned ...

journal_title：Infection and immunity

authors： Anderson C,Potter AA,Gerlach GF

更新日期：1991-11-01 00:00:00

abstract：:A total of 32 patients with Plasmodium falciparum malaria were studied. Of these, 23 had benign infections, and 9 had typical cerebral malaria. Cryoglobulins, circulating immune complexes detected by a C1q-binding assay, and hypocomplementemia were found in eight of nine patients with cerebral malaria. Raised levels o...

journal_title：Infection and immunity

authors： Adam C,Géniteau M,Gougerot-Pocidalo M,Verroust P,Lebras J,Gibert C,Morel-Maroger L

更新日期：1981-02-01 00:00:00

abstract：:The Salmonella typhimurium gene for Mn-cofactored superoxide dismutase (sodA) was cloned by complementation of an Escherichia coli sodA sodB mutant for growth on minimal medium. Sequence analysis revealed an open reading frame of 618 bp encoding a polypeptide with 97% identity to E. coli SodA. A S. typhimurium sodA mu...

journal_title：Infection and immunity

authors： Tsolis RM,Bäumler AJ,Heffron F

更新日期：1995-05-01 00:00:00

abstract：:Mast cell-deficient W/Wv mice and their mast cell-sufficient littermates were given infections of Trichinella spiralis. W/Wv mice were slower than their littermates to expel adult T. spiralis. Repair of the mast cell deficiency of W/Wv mice by bone marrow grafting was accompanied by accelerated expulsion of T. spirali...

journal_title：Infection and immunity

authors： Ha TY,Reed ND,Crowle PK

更新日期：1983-07-01 00:00:00

abstract：:The Lyme disease agent, Borrelia burgdorferi, is able to persistently infect humans and animals for months or years in the presence of an active immune response. It is not known how the organisms survive immune attack in the mammalian host. vlsE, a gene localized near one end of linear plasmid lp28-1 and encoding a su...

journal_title：Infection and immunity

authors： Zhang JR,Norris SJ

更新日期：1998-08-01 00:00:00

abstract：:Organ cultures of adult hamster trachea were used to evaluate the cytotoxic potential of cell fractions of Mycoplasma pneumoniae. Cytoplasm was essentially devoid of activity, whereas viable cells and membrane preparations, at a level of 25 mug of protein per ml, induced necrosis. Damage, as revealed by light and elec...

journal_title：Infection and immunity

authors： Gabridge MG,Johnson CK,Cameron AM

更新日期：1974-11-01 00:00:00

abstract：:The intracellular pathogen Listeria monocytogenes replicates mainly in resting macrophages and hepatocytes residing in infected tissues. Both innate and acquired resistance strongly depend on activation of listericidal capacities of macrophages by gamma interferon (IFN-gamma) produced by natural killer cells and T lym...

journal_title：Infection and immunity

authors： Szalay G,Hess J,Kaufmann SH

更新日期：1995-08-01 00:00:00

abstract：:In the present study, the roles of interleukin 12 (IL-12) and IL-18 and their possible interaction during superantigen-induced responses were studied by injection of staphylococcal enterotoxin B (SEB) into mice. These data suggest that the role of IL-12 in SEB-induced responses is limited to sustaining gamma interfero...

journal_title：Infection and immunity

authors： Lauw FN,Florquin S,Speelman P,van Deventer SJ,van der Poll T

更新日期：2001-09-01 00:00:00

abstract：:Transcutaneous immunization (TCI) is a new method for vaccine delivery that has been shown to induce immunity relevant to enteric disease vaccines. We evaluated the clinical safety and immunogenicity of a recombinant subunit vaccine against enterotoxigenic Escherichia coli (ETEC) delivered by TCI. Adult volunteers rec...

journal_title：Infection and immunity

authors： Güereña-Burgueño F,Hall ER,Taylor DN,Cassels FJ,Scott DA,Wolf MK,Roberts ZJ,Nesterova GV,Alving CR,Glenn GM

更新日期：2002-04-01 00:00:00

abstract：:Exposure of mycobacterial growth inhibitory factor (MycoIF) to trypsin, chymotrypsin, or neuraminidase decrease its ability to produce intracellular inhibition of mycobacterial growth within macrophages, suggesting that MycoIF was a glycoprotein. MycoIF was unaffected by deoxyribonuclease or ribonuclease. Supernatant ...

journal_title：Infection and immunity

authors： Cahall DL,Youmans GP

更新日期：1975-10-01 00:00:00

abstract：:The protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide (CP5) was examined in a modified model of catheter-induced endocarditis. Rats were catheterized by surgically passing a polyethylene catheter through the right carotid artery and aortic valve into the left ventricle. The ...

journal_title：Infection and immunity

authors： Lee JC,Park JS,Shepherd SE,Carey V,Fattom A

更新日期：1997-10-01 00:00:00

abstract：:Mannheimia haemolytica, a commensal organism of the upper respiratory tract in cattle, is the principal bacterial pathogen associated with the bovine respiratory disease complex. Adherence to the respiratory mucosa is a crucial event in its pathogenesis. However, the bacterial components that contribute to this proces...

journal_title：Infection and immunity

authors： Kisiela DI,Czuprynski CJ

更新日期：2009-01-01 00:00:00

abstract：:A genomic library of meningococcal DNA from a clinical isolate of Neisseria meningitidis was constructed in the expression vector lambda gt11. Outer membrane complex was prepared from the same strain and used to immunize rabbits to raise polyclonal anti-outer membrane complex serum. The amplified library was probed wi...

journal_title：Infection and immunity

authors： Barlow AK,Heckels JE,Clarke IN

更新日期：1987-11-01 00:00:00

abstract：:Leishmania-infected macrophages are potential antigen-presenting cells for CD4+ T lymphocytes, which recognize parasite antigens bound to major histocompatibility complex class II molecules (Ia). However, the intracellular sites where Ia and antigens may interact are far from clear, since parasites grow within the mod...

journal_title：Infection and immunity

authors： Antoine JC,Jouanne C,Lang T,Prina E,de Chastellier C,Frehel C

更新日期：1991-03-01 00:00:00

abstract：:Two distinct types of granulomas were produced in the draining lymph nodes by immunizing guinea pigs with Mycobacterium bovis BCG or Mycobacterium leprae, as reported earlier (Narayanan et al., J. Pathol. 134:253-265, 1981). In the BCG-induced granuloma there is successful containment, killing, and degradation of the ...

journal_title：Infection and immunity

authors： Mathew RC,Katayama I,Gupta SK,Curtis J,Turk JL

更新日期：1983-01-01 00:00:00

abstract：:Direct instillation of coxsackievirus B1 into the gastrointestinal tracts of albino mice caused viremia in more than 85% of the animals within 1 day. In pregnant mice infected early in gestation (7 days), the geometric mean titer of virus in the blood was lower (P = 0.02) and the duration of viremia was shorter (P = 0...

journal_title：Infection and immunity

authors： Modlin JF,Crumpacker CS

更新日期：1982-07-01 00:00:00

abstract：:We developed a human inhibition monoclonal enzyme-linked immunosorbent assay (HIMELISA) to investigate the human immune response to the lipooligosaccharides (LOS) of Neisseria meningitidis. Monoclonal antibodies (MAb) were used to define seven epitopes on four LOS molecules of a meningococcal strain (126E) previously ...

journal_title：Infection and immunity

authors： Estabrook MM,Mandrell RE,Apicella MA,Griffiss JM

更新日期：1990-07-01 00:00:00

abstract：:Spleen cell cultures from guinea pigs given legionella pneumophila vaccine in complete Freund adjuvant or as a sublethal infection were inhibited in their migration activity in vitro when incubated with specific antigen. Both direct and indirect migration inhibition assays revealed sensitization of the guinea pigs to ...

journal_title：Infection and immunity

authors： Friedman H,Widen R,Lee I,Klein T

更新日期：1983-09-01 00:00:00

abstract：:The serum antibody response to proteins encoded by the virulence-associated plasmid of Shigella flexneri was determined in monkeys challenged with virulent S. flexneri serotype 2a. With water-extractable antigen in an enzyme-linked immunosorbent assay, a significant increase in antibody titer against proteins from a p...

journal_title：Infection and immunity

authors： Oaks EV,Hale TL,Formal SB

更新日期：1986-07-01 00:00:00

abstract：:The effects of heat and chemical inactivation on the antigenicity and immunogenicity of Vibrio cholerae 1418 in rabbits were studied. V. cholerae 1418 was inactivated with heat and chemical inactivants (phenol or Formalin) alone or in combination. Enzyme-linked immunoassay systems employing whole cells of V. cholerae ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Germanier R

更新日期：1982-10-01 00:00:00

abstract：:By crossed immunoelectrophoresis and Western blotting (immunoblotting), it was shown that Borrelia burgdorferi expresses the 60-kilodalton Common Antigen (CA) that is cross-reactive with an equivalent antigen in a wide range of remotely related bacteria. B. burgdorferi CA is strongly immunogenic. A B. burgdorferi geno...

journal_title：Infection and immunity

authors： Hansen K,Bangsborg JM,Fjordvang H,Pedersen NS,Hindersson P

更新日期：1988-08-01 00:00:00

abstract：:Exoenzyme Y (ExoY) is a type III secretion system effector found in 90% of the Pseudomonas aeruginosa isolates. Although it is known that ExoY is a soluble nucleotidyl cyclase that increases the cytoplasmic levels of nucleoside 3',5'-cyclic monophosphates (cNMPs) to mediate endothelial Tau phosphorylation and permeabi...

journal_title：Infection and immunity

authors： He C,Zhou Y,Liu F,Liu H,Tan H,Jin S,Wu W,Ge B

更新日期：2017-08-18 00:00:00

abstract：:The Th1/Th2 cytokines involved in human periodontitis remain unclear; therefore, we established a humanized mouse model to investigate this issue in Actinobacillus actinomycetemcomitans-mediated periodontal infection. Quantitative-PCR analysis clearly demonstrates a predominantly mixed Th1 and Th2 expression profile a...

journal_title：Infection and immunity

authors： Teng YT

更新日期：2002-09-01 00:00:00

abstract：:Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low ...

journal_title：Infection and immunity

authors： Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM

更新日期：2016-03-24 00:00:00

abstract：:Nine goats were injected transthoracically with Pasteurella haemolytica A1 to determine if an extracellular bacterial enzyme, neuraminidase, was produced in vivo during infection with this organism. The principal group of goats (n = 9) each received 1 ml of 7.25 x 10(5) live P. haemolytica A1 cells in polyacrylate bea...

journal_title：Infection and immunity

authors： Straus DC,Purdy CW

更新日期：1994-10-01 00:00:00

abstract：:Infection with Giardia duodenalis is one of the most common causes of diarrheal disease in the world. While numerous studies have identified important contributions of adaptive immune responses to parasite control, much less work has examined innate immunity and its connections to the adaptive response during this inf...

journal_title：Infection and immunity

authors： Li E,Tako EA,Singer SM

更新日期：2016-03-24 00:00:00

abstract：:Intracellular growth of Legionella pneumophila occurs in a replication vacuole constructed by host proteins that regulate vesicular traffic from the host endoplasmic reticulum (ER). This process is promoted by a combination of approximately 300 Icm/Dot translocated substrates (IDTS). One of these proteins, Ceg9, was p...

journal_title：Infection and immunity

authors： Haenssler E,Ramabhadran V,Murphy CS,Heidtman MI,Isberg RR

更新日期：2015-09-01 00:00:00

abstract：:The type III capsular polysaccharide of group B streptococci (GBS) consists of a linear backbone with short side chains ending in residues of N-acetylneuraminic acid, or sialic acid. The presence of sialic acid on the surface of the organism inhibits activation of the alternative pathway of complement and is thought t...

journal_title：Infection and immunity

authors： Wessels MR,Haft RF,Heggen LM,Rubens CE

更新日期：1992-02-01 00:00:00