Intracellular responses of olfactory bulb granule cells to stimulating the horizontal diagonal band nucleus.

abstract：:Miniature endplate potentials were recorded from the isolated pectoralis cutaneous muscle of the frog during very stable recording conditions and low noise levels. Two to 5 x 10(3) miniature endplate potentials were filmed at eight unstressed junctions that met rigorous experimental criteria for analysis. Seven juncti...

journal_title：Neuroscience

authors： Kriebel ME,Motelica-Heino I

更新日期：1987-11-01 00:00:00

abstract：:Hippocampal neurogenesis in adult mammals is influenced by many factors. Lesioning of the entorhinal cortex is a standard model used to study injury and repair in the hippocampus. Here we use bromodeoxyuridine (BrdU) labeling combined with immunohistochemical identification using cell type specific markers to follow t...

journal_title：Neuroscience

authors： Gama Sosa MA,Wen PH,De Gasperi R,Perez GM,Senturk E,Friedrich VL Jr,Elder GA

更新日期：2004-01-01 00:00:00

abstract：:Basic fibroblast growth factor is a potent trophic factor with a wide spectrum of activity at various stages of neuronal development. In our studies on the effects of select lesions on the expression of growth factors, we observed that neurons of layer VIb of the rat cerebral cortex developed immunoreactivity for basi...

journal_title：Neuroscience

authors： Gómez-Pinilla F,Cotman CW

更新日期：1992-08-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGF-β) superfamily. BMPs, such as BMP2 and BMP4, exert its biological functions by interacting with membrane bound receptors belonging to the serine/threonine kinase family including bone morphogenetic protein receptor I (BMPRIA, BMPRI...

journal_title：Neuroscience

authors： Miyagi M,Mikawa S,Sato T,Hasegawa T,Kobayashi S,Matsuyama Y,Sato K

更新日期：2012-02-17 00:00:00

abstract：:Recent studies have shown that tachykinins mediate slow synaptic transmission to myenteric AH (afterhyperpolarising) neurons via neurokinin-3 receptors (NK(3)R). This study investigated a similar role for neurokinin-1 receptors (NK(1)R) and compared the effect of selective receptor antagonists on non-cholinergic slow ...

journal_title：Neuroscience

authors： Johnson PJ,Bornstein JC

更新日期：2004-01-01 00:00:00

abstract：:The nucleus of the solitary tract is the site of termination of primary afferent fibers running in the facial, glossopharyngeal and vagus nerves. The present study was performed to map the distribution of glutamatergic axons terminals in the rat nucleus of the solitary tract using immunodetection of vesicular glutamat...

journal_title：Neuroscience

authors： Lachamp P,Crest M,Kessler JP

更新日期：2006-01-01 00:00:00

abstract：:Ablation of capsaicin-sensitive afferent neurons enhances experimentally induced ulceration in the rat gastric mucosa, which suggests that these neurons are involved in gastric mucosal protection. To provide direct evidence for such a function it was investigated whether stimulation of afferent nerve endings by the in...

journal_title：Neuroscience

authors： Holzer P,Lippe IT

更新日期：1988-12-01 00:00:00

abstract：:The regional distribution of the specific D1 agonist [3H]SKF 38393 (SKF 38393, 2,3,4,5-tetra-hydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine) has been studied autoradiographically in the rat CNS. The binding of [3H]SKF 38393 to striatal sections was saturable, stereospecific, reversible, of high affinity (Kd = 9.9 nM) a...

journal_title：Neuroscience

authors： Dubois A,Savasta M,Curet O,Scatton B

更新日期：1986-09-01 00:00:00

abstract：:Mutations in the PI3K/Akt/mTOR signaling pathway or in the upstream negative regulator Pten cause human brain overgrowth disorders, such as focal cortical dysplasia and megalencephaly, and are characterized by the presence of hypertrophic neurons. These disorders often have a pediatric onset and a high comorbidity wit...

journal_title：Neuroscience

authors： Nikolaeva I,Kazdoba TM,Crowell B,D'Arcangelo G

更新日期：2017-06-23 00:00:00

abstract：:Visually elicited activity contributes to the formation of orderly connections in the optic tectum of frogs. Glutamate receptors of the N-methyl-D-aspartate class participate in this process. Blocking those receptors interferes with activity-dependent refinement of maps in normal frogs and of ocular dominance bands in...

journal_title：Neuroscience

authors： Udin SB,Scherer WJ,Constantine-Paton M

更新日期：1992-08-01 00:00:00

abstract：:The distribution of N-methyl-D-aspartate- (NMDA) and kainic acid- (KA) sensitive ionotropic glutamate receptors (iGluR) in the zebrafish olfactory bulb was assessed using an activity-dependent labeling method. Olfactory bulbs were incubated with an ion channel permeant probe, agmatine (AGB), and iGluR agonists in vitr...

journal_title：Neuroscience

authors： Edwards JG,Michel WC

更新日期：2003-01-01 00:00:00

abstract：:Long-term treatment with diazepam, a full allosteric modulator of the GABA(A) receptor, results in tolerance to its anticonvulsant effects, whereas an equipotent treatment with the partial allosteric modulator imidazenil does not produce tolerance. Use of subunit-specific antibodies linked to gold particles allowed an...

journal_title：Neuroscience

authors： Pesold C,Caruncho HJ,Impagnatiello F,Berg MJ,Fritschy JM,Guidotti A,Costa E

更新日期：1997-07-01 00:00:00

abstract：:In order to study structural alterations which occur after a defined unilateral cortical infarct, the hindlimb region of the rat cortex was photochemically lesioned. The infarcts caused edema restricted to the perilesional cortex which affected allocortical and isocortical areas differently. Postlesional changes in cy...

journal_title：Neuroscience

authors： Bidmon HJ,Jancsik V,Schleicher A,Hagemann G,Witte OW,Woodhams P,Zilles K

更新日期：1998-01-01 00:00:00

abstract：:The possible irreversible blockade of 5-hydroxytryptamine1 receptor subtypes 5-hydroxytryptamine1A, 5-hydroxytryptamine1B/5-hydroxytryptamine1D and 5-hydroxytryptamine1C by the chloramine 8-methoxy-2-(N-2'-chloropropyl,N-propyl)aminotetralin (8-MeO-2'-chloro-PAT) was investigated in rat brain sections by quantitative ...

journal_title：Neuroscience

authors： Radja F,Daval G,Emerit MB,Gallissot MC,Hamon M,Vergé D

更新日期：1989-01-01 00:00:00

abstract：:The purpose of this study was to determine the role of the axodendritic tree in the generation of bursting pacemaker activity in the identified Helix RPa1 neuron, which is homologous to the Aplysia R15 cell, and propagation of action potentials along the axons. In doing so, I used recording of RPa1 neuron electrical a...

journal_title：Neuroscience

authors： Kononenko NI

更新日期：2000-01-01 00:00:00

abstract：:The distribution of axons according to diameter has been examined in the optic nerve of old world monkeys. Axon diameters were measured from electron micrographs, and histograms were constructed at regular intervals across a section through the optic nerve to reveal the local axon diameter distribution. The total axon...

journal_title：Neuroscience

authors： Reese BE,Ho KY

更新日期：1988-10-01 00:00:00

abstract：:In this study, we describe a model of opiate sensitization characterized by a brief schedule of treatment with repeated morphine administrations. In this model, we investigated the changes produced by repeated morphine treatment on dopamine transmission at the level of the two major terminal dopaminergic areas, the do...

journal_title：Neuroscience

authors： Cadoni C,Di Chiara G

更新日期：1999-05-01 00:00:00

abstract：:Neural injury triggers changes in the expression of a large number of gene families. Particularly interesting are those encoding proteins involved in the generation, propagation or restoration of electric potentials. The expression of the Na+, K+-ATPase subunit isoforms (alpha, beta and gamma) was studied in dorsal ro...

journal_title：Neuroscience

authors： Arteaga MF,Gutiérrez R,Avila J,Mobasheri A,Díaz-Flores L,Martín-Vasallo P

更新日期：2004-01-01 00:00:00

abstract：:Longevity genes attenuate the aging process, but their expression in the brain during aging remains unknown. Loss of the majority of heteromeric brain nicotinic acetylcholine receptors (nAChRs) results in premature brain aging, and altered regulation of longevity genes could be involved. Using in situ hybridization, t...

journal_title：Neuroscience

authors： Huang PS,Son JH,Abbott LC,Winzer-Serhan UH

更新日期：2011-11-24 00:00:00

abstract：:The role of the oxytocin-containing projections to the autonomic nuclei of the spinal cord for lower urinary tract function has not been clarified. The hypothesis was tested that oxytocin acts as a mediator of bladder contraction at the spinal cord level. In conscious female rats undergoing continuous cystometry, intr...

journal_title：Neuroscience

authors： Pandita RK,Nylén A,Andersson KE

更新日期：1998-08-01 00:00:00

abstract：:Induction of heat shock/stress proteins is a key feature of a universal mechanism of cellular defence to injury known as the "stress response". The present study investigated whether heat shock protein expression correlates with the extent of neuronal injury inflicted by increasingly intense seizure activity. Limbic e...

journal_title：Neuroscience

authors： Gass P,Prior P,Kiessling M

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:This study aimed to clarify whether ischemia-induced early growth response 1 (EGR1) influenced the outcomes of experimental stroke by regulating brain-derived neurotrophic factor (BDNF) expression. METHODS AND RESULTS:To mimic ischemia, mice were subjected to middle cerebral artery occlusion, and neurons chall...

journal_title：Neuroscience

authors： Yang L,Jiang Y,Wen Z,Xu X,Xu X,Zhu J,Xie X,Xu L,Xie Y,Liu X,Xu G

更新日期：2015-04-02 00:00:00

abstract：:Compelling lines of evidence indicate that overexpression of dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) in subjects with trisomy 21 (Down syndrome[DS]) contributes to the abnormal structure and function of the DS brain. In the present study, we used a novel, phospho-dependent antibody r...

journal_title：Neuroscience

authors： Kida E,Walus M,Jarząbek K,Palminiello S,Albertini G,Rabe A,Hwang YW,Golabek AA

更新日期：2011-11-10 00:00:00

abstract：:Cortical pyramidal neurons are considered to be less excitable in the immature cortex than in adults. Our previous report revealed that a negative feedback regulation of membrane excitability is highly correlated with a novel form of calcium release from inositol-1,4,5-trisphosphate (IP(3))-sensitive calcium stores (I...

journal_title：Neuroscience

authors： Yamamoto K,Nakano M,Hashimoto K,Shimohama S,Kato N

更新日期：2002-01-01 00:00:00

abstract：:Dorsal vagal complex (DVC) AMPK regulation of food intake in the estradiol-treated ovariectomized (OVX) female rat is energy state-dependent. Here, RT-PCR array technology was used to identify estradiol-sensitive AMPK-regulated DVC signal transduction pathways that exhibit differential reactivity to sensor activation ...

journal_title：Neuroscience

authors： Ibrahim BA,Alenazi FSH,Briski KP

更新日期：2015-01-22 00:00:00

abstract：:The effects of treatment with the antidepressant drug imipramine on neuropeptide Y immunoreactivity were studied immunocytochemically in the rat brain cortex and hypothalamus. It was found that the level of neuropeptide Y immunoreactivity in the cortex was significantly lowered three and 24 h after the last dose of ch...

journal_title：Neuroscience

authors： Smiałowska M,Legutko B

更新日期：1991-01-01 00:00:00

abstract：:The effects of excitatory amino acid antagonists on extracellular field potentials in the olfactory bulb produced by lateral olfactory tract stimulation were analysed in vivo. The compounds tested D-2-amino-5-phosphonovalerate, L-(+)2-amino-4-phosphonobutyrate, gamma-D-glutamylglycine, L-glutamic acid diethylester and...

journal_title：Neuroscience

authors： Jacobson I,Butcher S,Hamberger A

更新日期：1986-09-01 00:00:00

abstract：:Investigation of rhythmic discharges may provide insights into integrative mechanisms underlying nervous system control of effectors. We have previously shown that, in CNS-intact, anesthetized rats, cutaneous sympathetic vasoconstrictor neurones innervating thermoregulatory circulations exhibit a robust rhythmicity in...

journal_title：Neuroscience

authors： Collins DR,Gilbey MP

更新日期：2003-01-01 00:00:00

abstract：:Dorsal root ganglion neurons innervating skin via the saphenous nerve, muscle via the gastrocnemius nerve and viscera via the splanchnic nerve, were identified by retrograde tracing with Fast Blue applied to the cut nerve. Only neuronal profiles with nuclei were counted. At the survival times used no changes in immuno...

journal_title：Neuroscience

authors： Perry MJ,Lawson SN

更新日期：1998-07-01 00:00:00

abstract：:Oscillatory activity is a prominent characteristic of electrophysiological recordings in the olfactory system and has been proposed to play a key role in encoding olfactory representations. Studies in several systems have shown that some aspects of information coding involve characteristics that intertwine spikes and ...

journal_title：Neuroscience

authors： Litaudon P,Garcia S,Buonviso N

更新日期：2008-10-15 00:00:00