Maternal and perinatal risk factors for Wilms' tumor: a nationwide nested case-control study in Sweden.


:This report describes maternal and perinatal risk factors for Wilms' tumor analyzed in a case-control study nested in a nationwide cohort in Sweden. The Swedish National Cancer Registry ascertained 110 cases from among successive birth cohorts from 1973 through 1984, identified by the Swedish Medical Birth Registry, the latter based on medical records. From the Birth Registry, we matched 5 controls without cancer to each case by sex and date of birth. Wilms'-tumor children were more likely to have mothers who had been exposed to penthrane (methoxyflurane) anesthesia during delivery than mothers of controls (odds ratio (OR) = 2.4; 95% confidence interval (CI) 1.1 to 5.1); this excess risk was higher in females than males and increased with age at diagnosis. Wilms'-tumor cases were also more likely to have had physiologic jaundice (OR = 2.3; 95% CI 1.1 to 5.0). Higher parity of the mother decreased the risk of Wilms' tumor among females (OR = 0.7; 95% CI 0.5 to 1.0). We were unable to confirm the reported increased risks of Wilms' tumor for those with high birth weights or with a maternal history of hypertension or fluid retention during pregnancy, nor did we find any association with mother's age at delivery, previous stillbirth, previous live birth, gestational length or height of the child.


Int J Cancer


Lindblad P,Zack M,Adami HO,Ericson A





Has Abstract


1992-04-22 00:00:00












  • Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.

    abstract::We previously found that the gene encoding the Myelin and Lymphocyte protein, MAL, was among the most highly expressed genes in serous ovarian cancers from short-term survivors (<3 years) relative to those of long-term survivors (>7 years). In the present study, we have found that this difference in expression is part...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Lee PS,Teaberry VS,Bland AE,Huang Z,Whitaker RS,Baba T,Fujii S,Secord AA,Berchuck A,Murphy SK

    更新日期:2010-03-15 00:00:00

  • Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA.

    abstract::The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies on the generation of potent DC capable of presenting tumor antigens such as carcinoembryonic antigen (CEA). It is unknown whether the T cells of patients with advanced malignancies can be reliably stimulated against tumor an...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Nair SK,Hull S,Coleman D,Gilboa E,Lyerly HK,Morse MA

    更新日期:1999-07-02 00:00:00

  • Heterogeneity of colon and rectum cancer incidence across 612 SEER counties, 2000-2014.

    abstract::Recent analyses have suggested decreases over time in colorectal cancer incidence at older ages (≥55 years) but increases at younger ages (20-54 years). Understanding the geographic heterogeneity of incidence facilitates resource allocation for potential interventions and advances our knowledge of differential etiolog...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Chernyavskiy P,Kennerley VM,Jemal A,Little MP,Rosenberg PS

    更新日期:2019-04-15 00:00:00

  • Candidate regions of tumor suppressor locus on chromosome 9q31.1 in gastric cancer.

    abstract::Loss of heterozygosity (LOH) is an important event of tumorigenesis. In gastric cancer, we found a novel region of LOH in chromosome 9q having about 800 kb deletions at 9q31.1. The microsatellite marker D9S938 in that region exhibiting the highest LOH frequency, 56.5%. In addition, the LOH at 9q31.1 did not show any r...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Kakinuma N,Kohu K,Sato M,Yamada T,Nakajima M,Akiyama T,Ohwada S,Shibanaka Y

    更新日期:2004-03-01 00:00:00

  • Mutational analysis of Bax and Bcl-2 in childhood acute lymphoblastic leukaemia.

    abstract::In childhood acute lymphoblastic leukaemia there are large interpatient variations in levels of the apoptosis-regulating proteins Bax and Bcl-2, but the molecular basis for this variation is unknown. Point-mutations in bax have been reported in cell lines derived from haematological malignancies. Frameshift mutations,...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Salomons GS,Buitenhuis CK,Martínez Muñoz C,Verwijs-Jassen M,Behrendt H,Zsiros J,Smets LA

    更新日期:1998-06-19 00:00:00

  • Suppression of intracellular Cu-Zn SOD results in enhanced motility and metastasis of Meth A sarcoma cells.

    abstract::We have previously described an inverse relationship between Cu-Zn superoxide dismutase (SOD) activity and invasiveness of a clone of human tongue cancer cells. In these cells, suppression of Cu-Zn SOD activity by transfection with anti-sense cDNA enhanced motility in vitro. The present studies were undertaken to dete...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Tanaka M,Kogawa K,Nishihori Y,Kuribayashi K,Nakamura K,Muramatsu H,Koike K,Sakamaki S,Niitsu Y

    更新日期:1997-10-09 00:00:00

  • Poor oral health is associated with an increased risk of esophageal squamous cell carcinoma - a population-based case-control study in China.

    abstract::To further examine the association between oral hygiene and esophageal squamous cell carcinoma (ESCC) risk and the effect modification of other exposures, we conducted a population-based case-control study between 2010 and 2012 in Taixing, China, a high-risk area for ESCC. Cases were primarily recruited from endoscopy...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Chen X,Yuan Z,Lu M,Zhang Y,Jin L,Ye W

    更新日期:2017-02-01 00:00:00

  • In vitro and in vivo modulation of multi-drug resistance with amiodarone.

    abstract::The modulating effect on drug resistance of amiodarone (AM) and its metabolite desethylamiodarone (DEA) was studied in a P-glycoprotein-positive human colon carcinoma cell line COLO 320, and a human small-cell lung carcinoma cell line GLC4 and its adriamycin (Adr)-resistant subline GLC4-Adr (both P-glycoprotein-negati...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: van der Graaf WT,de Vries EG,Uges DR,Nanninga AG,Meijer C,Vellenga E,Mulder PO,Mulder NH

    更新日期:1991-06-19 00:00:00

  • Augmentation of natural killer activity by pyran copolymer in mice.

    abstract::Treatment of older mice with pyran copolymer, a known interferon-inducer, was found to result in a rapid boosting of cell-mediated cytolytic activity against YAC-1 tumor target cells. The effector cells were characterized as being non-adherent and were presumed to be natural killer (NK) cells. Augmentation occurred in...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Santoni A,Puccetti P,Riccardi C,Herberman RB,Bonmassar E

    更新日期:1979-11-15 00:00:00

  • Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

    abstract::Barrett's esophagus (BE) is a metaplastic condition caused by chronic gastroesophageal reflux which represents an early step in the development of esophageal adenocarcinoma (EAC). Single-nucleotide polymorphism microarray (SNP-chip) analysis is a novel, precise, high-throughput approach to examine genomic alterations ...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Akagi T,Ito T,Kato M,Jin Z,Cheng Y,Kan T,Yamamoto G,Olaru A,Kawamata N,Boult J,Soukiasian HJ,Miller CW,Ogawa S,Meltzer SJ,Koeffler HP

    更新日期:2009-11-15 00:00:00

  • Small interfering RNA-mediated CXCR1 or CXCR2 knock-down inhibits melanoma tumor growth and invasion.

    abstract::CXCR1 and CXCR2 are receptors for CXCL-8 and are differentially expressed on melanoma and endothelial cells. In this study, we determined the functional role of these receptors in melanoma progression. We stably knock-down the expression of CXCR1 and/or CXCR2 in A375-SM (SM; high metastatic) human melanoma cells by sh...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Singh S,Sadanandam A,Varney ML,Nannuru KC,Singh RK

    更新日期:2010-01-15 00:00:00

  • Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses.

    abstract::Adenoviral oncolysis is a promising new modality for treatment of cancer based on selective viral replication in tumor cells. However, tumor cell killing by adenoviral oncolysis needs to be improved to achieve therapeutic benefit in the clinic. Towards this end, the activation of anti-tumor immunity by adenoviral onco...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Schierer S,Hesse A,Müller I,Kämpgen E,Curiel DT,Schuler G,Steinkasserer A,Nettelbeck DM

    更新日期:2008-01-01 00:00:00

  • Parental smoking and risk of childhood brain tumors.

    abstract::Childhood brain tumors (CBT) are the leading cause of cancer death in children, yet their etiology remains largely unknown. Tobacco smoke contains 61 known carcinogens and increases the risk of several adult cancers. This study investigated associations between parental smoking and risk of CBT in a population-based ca...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Milne E,Greenop KR,Scott RJ,Ashton LJ,Cohn RJ,de Klerk NH,Armstrong BK

    更新日期:2013-07-01 00:00:00

  • Prevalence of Kaposi's sarcoma-associated herpesvirus infection in sex workers and women from the general population in Spain.

    abstract::Transmission routes of Kaposi's sarcoma-associated herpesvirus (KSHV) in the general population are poorly understood. Whereas sexual transmission appears to be common in homosexual men, the evidence for heterosexual transmission is less convincing. In our study, prevalence of KSHV infection was examined among women i...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: de Sanjosé S,Marshall V,Solà J,Palacio V,Almirall R,Goedert JJ,Bosch FX,Whitby D

    更新日期:2002-03-01 00:00:00

  • Thyroid and androgen receptor signaling are antagonized by μ-Crystallin in prostate cancer.

    abstract::Androgen deprivation therapy (ADT) remains a key approach in the treatment of prostate cancer (PCa). However, PCa inevitably relapses and becomes ADT resistant. Besides androgens, there is evidence that thyroid hormone thyroxine (T4) and its active form 3,5,3'-triiodo-L-thyronine (T3) are involved in the progression o...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Aksoy O,Pencik J,Hartenbach M,Moazzami AA,Schlederer M,Balber T,Varady A,Philippe C,Baltzer PA,Mazumder B,Whitchurch JB,Roberts CJ,Haitel A,Herac M,Susani M,Mitterhauser M,Marculescu R,Stangl-Kremser J,Hassler MR,Kr

    更新日期:2021-02-01 00:00:00

  • Substrate-dependent effect of epidermal growth factor on intercellular adhesion and synthesis of triton-insoluble proteins in human carcinoma A431 cells.

    abstract::Human epidermoid carcinoma A431 cells attach more rapidly to collagen type-I and -IV substrates than to surfaces coated with laminin or fibronectin. The diminished intercellular interaction and rounding up manifested when these cells are exposed to epidermal growth factor (EGF) in tissue culture plastic or collagen fi...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Rieber M,Gil F,Rieber MS,Urbina C

    更新日期:1986-03-15 00:00:00

  • The mTOR kinase inhibitor everolimus synergistically enhances the anti-tumor effect of the Bruton's tyrosine kinase (BTK) inhibitor PLS-123 on Mantle cell lymphoma.

    abstract::Mantle cell lymphoma (MCL) is an aggressive and incurable malignant disease. Despite of general chemotherapy, relapse and mortality are common, highlighting the need for the development of novel targeted drugs or combination of therapeutic regimens. Recently, several drugs that target the B-cell receptor (BCR) signali...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Li J,Wang X,Xie Y,Ying Z,Liu W,Ping L,Zhang C,Pan Z,Ding N,Song Y,Zhu J

    更新日期:2018-01-01 00:00:00

  • Germline APOBEC3B deletion increases somatic hypermutation in Asian breast cancer that is associated with Her2 subtype, PIK3CA mutations, and immune activation.

    abstract::A 30-kb deletion that eliminates the coding region of APOBEC3B (A3B) is >5 times more common in women of Asian compared to European descent. This polymorphism creates a chimera with the APOBEC3A (A3A) coding region and A3B 3'UTR, and is associated with an increased risk for breast cancer in Asian women. Here, we explo...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Pan JW,Zabidi MMA,Chong BK,Meng MY,Ng PS,Hasan SN,Sandey B,Bahnu S,Rajadurai P,Yip CH,Rueda OM,Caldas C,Chin SF,Teo SH

    更新日期:2021-01-07 00:00:00

  • Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo.

    abstract::In addition to the known function in the glycolytic pathway, phosphoglycerate kinase 1 (PGK-1) promotes reduction of plasmin disulfide bonds leading to angiostatin formation and inhibition of tumor angiogenesis. In this study, the effects of PGK-1 on anti- tumor immunity against lung cancer were evaluated using the Te...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Tang SJ,Ho MY,Cho HC,Lin YC,Sun GH,Chi KH,Wang YS,Jhou RS,Yang W,Sun KH

    更新日期:2008-12-15 00:00:00

  • Preservation of chromosome and DNA characteristics of human colorectal adenocarcinomas after passage in nude mice.

    abstract::Twenty-seven human colorectal adenocarcinomas were implanted s.c. into nude mice. A comparative study of chromosomes and DNA between fresh tumor (FT) and xenografted tumor cells (XT) could be performed in 9 cases. Losses or deletions were consistently found in FTs as well as in XTs, particularly on chromosomes 17 and/...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Lefrançois D,Olschwang S,Delattre O,Muleris M,Dutrillaux AM,Thomas G,Dutrillaux B

    更新日期:1989-11-15 00:00:00

  • Radiation-related mortality among offspring of atomic bomb survivors: a half-century of follow-up.

    abstract::Our objective was to examine whether parental exposure to atomic bomb radiation has led to increased cancer and/or noncancer mortality rates among the offspring. We studied 41,010 subjects born from May 1946 through December 1984 (i.e., conceived between 1 month and 38 years after the bombings) and surviving for at le...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Izumi S,Suyama A,Koyama K

    更新日期:2003-11-01 00:00:00

  • Exposure to environmental tobacco smoke and risk of adenocarcinoma of the lung.

    abstract::We conducted a case-control study of adenocarcinoma of the lung and exposure to environmental tobacco smoke (ETS) in 7 countries. We interviewed 70 cases of adenocarcinoma of the lung and 178 population or hospital controls. All subjects had smoked fewer than 400 cigarettes in their lifetimes. Ever exposure to ETS fro...

    journal_title:International journal of cancer

    pub_type: 杂志文章,多中心研究


    authors: Boffetta P,Ahrens W,Nyberg F,Mukeria A,Brüske-Hohlfeld I,Fortes C,Constantinescu V,Simonato L,Batura-Gabryel H,Lea S,Gaborieau V,Benhamou S

    更新日期:1999-11-26 00:00:00

  • Erratum: Increased DNA methyltransferase expression in rhabdomyosarcomas. Int. J. Cancer, 83, 10-14 (1999).

    abstract::Chen, B., Liu, X., Savell, V.H., Dilday, B.R., Johnson, M.W., Jenkins, J.J., and Parham, D.M., Increased DNA methyltransferase expression in rhabdomyosarcomas. Int. J. Cancer, 83, 10-14 (1999). Due to a printer's error, the bottom of Figure 3 was cut off after the proofs had been approved by the author. The correct fi...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Chen B,Liu X,Savell VH,Dilday BR,Johnson MW,Jenkins JJ,Parham DM

    更新日期:1999-12-10 00:00:00

  • A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer.

    abstract::The role of miRNAs with tumor suppressive activity in liver cancer has been well studied. However, little is known about potential oncomiRs in HCC. In our study, we conducted a systematic evaluation of candidate oncomiRs and found that upregulation of miR-18a and miR-25 in HCC was associated with poor patient survival...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Sanchez-Mejias A,Kwon J,Chew XH,Siemens A,Sohn HS,Jing G,Zhang B,Yang H,Tay Y

    更新日期:2019-01-15 00:00:00

  • LAF-4 is aberrantly expressed in human breast cancer.

    abstract::LAF-4, which encodes a nuclear protein with transactivation potential, is fused to the MLL gene in acute lymphoblastic leukemia (ALL). We identified LAF-4 as a gene that is transcriptionally deregulated in breast tumors and thus may have a pathological role in mammary tumorigenesis. In line with the previous finding t...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: To MD,Faseruk SA,Gokgoz N,Pinnaduwage D,Done SJ,Andrulis IL

    更新日期:2005-07-01 00:00:00

  • Spontaneous and induced primary oncogenesis in natural killer (NK)-cell-deficient beige mutant mice.

    abstract::Spontaneous tumor development and primary oncogenesis were compared in a large number of NK4-deficient, homozygous C57Bl/6-bg/bg mice and their NK normal, heterozygous +/bg littermate controls. In a group of 167 retired breeders followed for spontaneous tumors, the probability of survival for mice eventually dying wit...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Haliotis T,Ball JK,Dexter D,Roder JC

    更新日期:1985-04-15 00:00:00

  • Long-term results of neoadjuvant radiation therapy for breast cancer.

    abstract::Our aim was to determine the long-term outcome and the possible role of neoadjuvant (preoperative) radiation therapy for breast cancers unsuitable for primary conservative surgery. From 1977 to 1992, 75 unifocal non-inflammatory and non-metastatic T2 and T3 breast cancers were treated in our department. All these pati...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Calitchi E,Kirova YM,Otmezguine Y,Feuilhade F,Piedbois Y,Le Bourgeois JP

    更新日期:2001-08-20 00:00:00

  • Hormone sensitivity in vitro and in vivo of v-ras-transfected MCF-7 cell derivatives.

    abstract::Human mammary carcinoma cell lines (MCF-7) were analysed for their hormone sensitivity before and after transfection with a v-Ha-ras oncogene or with a neomycin-resistance gene followed by selection in vitro or in vivo. Our aim was to test how the expression of the ras oncogene would influence the estradiol sensitivit...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Van Roy F,Mareel M,Vleminckx K,Beyaert R,Fiers W,Devleeschouwer N,Muquardt C,Legros N,Bracke M,Leclercq G

    更新日期:1990-09-15 00:00:00

  • Transformation of normal human melanocytes and non-malignant nevus cells by adenovirus 12-SV40 hybrid virus.

    abstract::Infection of normal human melanocyte and nevus cultures with an adenovirus 12-Simian Virus 40 hybrid virus (Ad12-SV40) produced transformed cells that expressed SV40-T antigen. The Ad12-SV40 cells exhibited rapid cell proliferation to high cell densities and efficient growth in soft agar, but none of 15 transformed me...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Jambrosic J,Mancianti ML,Ricciardi R,Sela BA,Koprowski H,Herlyn M

    更新日期:1989-12-15 00:00:00

  • Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome.

    abstract::To identify characteristics of gastric cancer associated with hereditary non-polyposis colorectal cancer (HNPCC), we gathered clinical data and tumor samples relating to patients recorded in the Finnish HNPCC registry. Our series included 51 families with a characterized mutation and/or that met the Amsterdam criteria...

    journal_title:International journal of cancer

    pub_type: 杂志文章


    authors: Aarnio M,Salovaara R,Aaltonen LA,Mecklin JP,Järvinen HJ

    更新日期:1997-10-21 00:00:00