Interaction of human immunodeficiency and papilloma viruses: association with anal epithelial abnormality in homosexual men.

abstract：:Four human colon cancer cell lines (SW620, LS 180, DLD-I, and HCT-15) and Adriamycin-resistant sub-lines with varying degrees of P-glycoprotein expression were studied to evaluate the reversibility of Adriamycin resistance in human colon cancer. Two groups of cell lines were studied. In the first, including a series o...

journal_title：International journal of cancer

authors： Lai GM,Chen YN,Mickley LA,Fojo AT,Bates SE

更新日期：1991-11-11 00:00:00

abstract：:MAGE genes are frequently expressed in several types of human malignancy and code for antigens recognized by cytotoxic T lymphocytes. We have previously described a monoclonal antibody (MAb), named 6C1, that recognizes the MAGE-1 protein and cross-reacts with a 72-kDa protein present in lysates of melanoma cells such ...

journal_title：International journal of cancer

authors： Rimoldi D,Salvi S,Reed D,Coulie P,Jongeneel VC,De Plaen E,Brasseur F,Rodriguez AM,Boon T,Cerottini JC

更新日期：1999-09-09 00:00:00

abstract：:Prostate stem cell antigen (PSCA) and prostate-specific antigen (PSA) are overexpressed in most prostate cancers. PSCA- and PSA-derived, HLA-A2 binding peptides are specific targets for T-cell responses in vitro. A phase I/II trial was performed to demonstrate feasibility, safety and induction of antigen-specific immu...

journal_title：International journal of cancer

authors： Thomas-Kaskel AK,Zeiser R,Jochim R,Robbel C,Schultze-Seemann W,Waller CF,Veelken H

更新日期：2006-11-15 00:00:00

abstract：:Messenger RNA differential display was used to study liver-gene expression in paired tumor and non-tumor tissues from hepatocellular carcinoma (HCC) patients. mRNA differential display and Northern-blot analyses showed that a 0.8-kb cDNA fragment was diminished or absent from the tumorous tissues of 7 HCC patients. Th...

journal_title：International journal of cancer

authors： Chen YM,Shiu JY,Tzeng SJ,Shih LS,Chen YJ,Lui WY,Chen PH

更新日期：1998-03-02 00:00:00

abstract：:The interactions of MCF-7 tumor cells with human vascular endothelial cells (EC) and subendothelial extracellular matrices (ECM) were morphologically observed by electron microscopy and quantitatively evaluated by labelling tumor cells with 111Indium-oxine. MCF-7 tumor cells adhered more rapidly to ECM than to the api...

journal_title：International journal of cancer

authors： Abecassis J,Millon-Collard R,Klein-Soyer C,Nicora F,Fricker JP,Beretz A,Eber M,Muller D,Cazenave JP

更新日期：1987-10-15 00:00:00

abstract：:Specific types of human papillomaviruses (HPV) are associated with most cases of pre-invasive and invasive neoplasia of the uterine cervix. HLA phenotype influences susceptibility and resistance to viral infections and may therefore influence the course of HPV-associated tumors. Some data suggest that specific HLA cla...

journal_title：International journal of cancer

authors： Sastre-Garau X,Loste MN,Vincent-Salomon A,Favre M,Mouret E,de la Rochefordiere A,Durand JC,Tartour E,Lepage V,Charron D

更新日期：1996-06-21 00:00:00

abstract：:The miR-34 family members are direct transcriptional targets of tumor suppressor p53, and loss of miR-34 function can impair p53-mediated cell cycle arrest and apoptosis. A potentially functional SNP rs4938723 (T > C) was found in the promoter region of pri-miR-34b/c (423 bp from the transcription start site), located...

journal_title：International journal of cancer

authors： Xu Y,Liu L,Liu J,Zhang Y,Zhu J,Chen J,Liu S,Liu Z,Shi H,Shen H,Hu Z

更新日期：2011-01-15 00:00:00

abstract：:The relationship between renal-cell cancer (RCC) and occupation was investigated in an international multicenter population-based case-control study. Study centers in Australia, Denmark, Germany, Sweden and the United States interviewed 1732 incident RCC cases and 2309 controls. Significant associations were found wit...

journal_title：International journal of cancer

authors： Mandel JS,McLaughlin JK,Schlehofer B,Mellemgaard A,Helmert U,Lindblad P,McCredie M,Adami HO

更新日期：1995-05-29 00:00:00

abstract：:Ionizing radiation remains a major therapeutic tool against human cancers, especially epithelial tumors, which account for the majority of human malignancies. Although Fas and Fas-L are essential determinants of apoptosis, few data support their role in the cytotoxic effect of ionizing radiation. Epstein-Barr-virus (E...

journal_title：International journal of cancer

authors： Abdulkarim B,Sabri S,Deutsch E,Vaganay S,Marangoni E,Vainchenker W,Bongrand P,Busson P,Bourhis J

更新日期：2000-04-15 00:00:00

abstract：:To examine the relationship between human T-lymphotrophic virus type I (HTLV-I) proviral DNA and its expression in the lymph nodes, HTLV-I DNA and tax/rex mRDA were directly amplified by polymerase chain reaction in situ hybridization (PCR/ISH), and reverse transcription (RT)-PCR/ISH [RT-PCR/ISH]. We studied 24 lymph ...

journal_title：International journal of cancer

authors： Ohshima K,Suzumiya J,Izumo S,Mukai Y,Tashiro K,Kikuchi M

更新日期：1996-03-28 00:00:00

abstract：:The kinetics of the immune response of hamsters transplanted with virus-free SV40 tumor cells (TSV5) to two SV40-coded non-structural proteins of 94,000 daltons (T antigen) and 17,000 daltons (t antigen) was studied in order to determine if the variation in the immune reactivity of serum from tumor-bearing animals tow...

journal_title：International journal of cancer

authors： Ransom JH,Thompson DL,Tevethia SS

更新日期：1982-02-15 00:00:00

abstract：:Using radioiodinated Staphylococcus aureus protein A [125I]SPA to measure syngeneic, allogeneic and heterogeneic IgG bound to murine tumor cells, we performed a serological analysis of surface antigens of 8 solid tumors and 2 leukemias of BALB/c mice (3 chemically-induced colon carcinomas, 3 chemically-induced sarcoma...

journal_title：International journal of cancer

authors： Cleveland PH,Belnap LP,Knotts FB,Nayak SK,Baird SM,Pilch YH

更新日期：1979-03-15 00:00:00

abstract：:Tumor-induced immunosuppression remains a major challenge for immunotherapy of cancer patients. To further elucidate why an allogeneic gene-modified [interleukin-7 (IL-7)/CD80-cotransfected] renal cell cancer (RCC) vaccine failed to induce clinically relevant TH-1-polarized immune responses, peripheral blood mononucle...

journal_title：International journal of cancer

authors： Flörcken A,Grau M,Wolf A,Weilemann A,Kopp J,Dörken B,Blankenstein T,Pezzutto A,Lenz P,Lenz G,Westermann J

更新日期：2015-04-15 00:00:00

abstract：:Immunological studies are presented on a patient with a long clinical history suggesting the existence of a tumor-specific immune response. His tumor, first considered benign, progressed to a highly malignant osteosarcoma. Cell-mediated immune reactivity against biopsy cells and against tumor extract was detected in v...

journal_title：International journal of cancer

authors： Vanky F,Klein E,Cornain S,Bakács T,Stjernswärd J,Nilsonne U

更新日期：1976-09-15 00:00:00

abstract：:Cord blood transplantation (CBT) is an effective option for treating hematological malignancies, but graft failure (GF) remains the primary cause of therapy failure. Thus, based on myeloablative conditioning (MAC) of busulfan with cyclophosphamide (Bu/Cy) or total body irradiation with Cy (TBI/Cy), fludarabine (Flu) w...

journal_title：International journal of cancer

authors： Sun Z,Liu H,Luo C,Geng L,Zheng C,Tang B,Zhu X,Tong J,Wang X,Ding K,Wan X,Zhang L,Yao W,Song K,Zhang X,Wu Y,Yang H,Han Y,Liu X,Zhu W,Wu J,Wang Z

更新日期：2018-08-01 00:00:00

abstract：:CXCR1 and CXCR2 are receptors for CXCL-8 and are differentially expressed on melanoma and endothelial cells. In this study, we determined the functional role of these receptors in melanoma progression. We stably knock-down the expression of CXCR1 and/or CXCR2 in A375-SM (SM; high metastatic) human melanoma cells by sh...

journal_title：International journal of cancer

authors： Singh S,Sadanandam A,Varney ML,Nannuru KC,Singh RK

更新日期：2010-01-15 00:00:00

abstract：:The influence of elevated lactate concentrations, as found in tumor microregions, on cellular growth, viability, and metabolic state was studied employing the multicellular spheroid model. Spheroids of EMT6/Ro cells were cultured at 37 degrees C in 5% or 20% (v/v) oxygen, using stirred media with various concentration...

journal_title：International journal of cancer

authors： Bourrat-Floeck B,Groebe K,Mueller-Klieser W

更新日期：1991-03-12 00:00:00

abstract：:The role of gastrin in the control of growth of renal G401 cells isolated from a human nephroblastoma (Wilms' tumour) was investigated. G401 cell growth was enhanced in the presence of exogenous gastrin. Addition of anti-gastrin antibodies to serum-free medium significantly inhibited the growth of G401 cells. G401 cel...

journal_title：International journal of cancer

authors： Blackmore M,Doherty E,Manning JE,Hirst BH

更新日期：1994-05-01 00:00:00

abstract：:Aberrant methylation of CpG islands (CGI) not only plays a role in gene silencing, but is also a potential cancer biomarker. To identify more CGI aberrantly methylated in human breast cancers, we carried out a genome-wide search for aberrant methylation, using methylation-sensitive-representational difference analysis...

journal_title：International journal of cancer

authors： Miyamoto K,Fukutomi T,Akashi-Tanaka S,Hasegawa T,Asahara T,Sugimura T,Ushijima T

更新日期：2005-09-01 00:00:00

abstract：:Chile's gallbladder cancer rates are among the highest in the world, being the leading cause of cancer deaths among Chilean women. To provide insights into the etiology of gallbladder cancer, we conducted an ecologic study examining the geographical variation of gallbladder cancer and several putative risk factors. Th...

journal_title：International journal of cancer

authors： Andia ME,Hsing AW,Andreotti G,Ferreccio C

更新日期：2008-09-15 00:00:00

abstract：:In a series of 135 patients with renal-cell carcinomas (followed up for a mean of 9.5 years), a variety of clinical and histological factors were analyzed in relation to morphometric measurements of the nuclear parameters in the primary tumours to establish their value as prognostic factors. Clinical, histological and...

journal_title：International journal of cancer

authors： Eskelinen M,Lipponen P,Aitto-Oja L,Hall O,Syrjänen K

更新日期：1993-10-21 00:00:00

abstract：:Therapy-induced senescence (TIS) as a permanent growth arrest can be induced by various stimuli, including anticancer compounds. TIS emerged as a promising strategy to overcome resistance phenomena. However, senescent cancer cells might regain proliferation activity in vivo or even secrete tumor-promoting cytokines. T...

journal_title：International journal of cancer

authors： Weiland T,Lampe J,Essmann F,Venturelli S,Berger A,Bossow S,Berchtold S,Schulze-Osthoff K,Lauer UM,Bitzer M

更新日期：2014-01-01 00:00:00

abstract：:Very late antigen-4 (VLA-4) composed of alpha 4 and beta 1, a member of the beta 1-integrin subfamily, facilitates cell-to-cell interaction with vascular cell-adhesion molecule-1 (VCAM-1) on endothelial cells (EC). Attachment of blood-borne tumor cells to EC is a crucial step for hematogenous metastasis, and VLA-4-pos...

journal_title：International journal of cancer

authors： Tomita Y,Saito T,Saito K,Oite T,Shimizu F,Sato S

更新日期：1995-03-16 00:00:00

abstract：:Leukocyte functions (superoxide production and phagocytosis) were evaluated in patients with testicular cancer who had undergone super-high-dose chemotherapy (SHDT) with peripheral blood stem cell transplantation (PBSCT). In 5 patients with advanced or relapsed testicular cancer who received 8 cycles of SHDT with PBSC...

journal_title：International journal of cancer

authors： Yamada Y,Hara I,Gohji K,Okada H,Arakawa S,Kamidono S

更新日期：1997-07-03 00:00:00

abstract：:Down-regulation of E-cadherin function is characteristic of cancer cells and might involve the small G-protein Rho family, including Rac1 and Cdc42. IQGAP1 has been reported to be one of the target proteins of Rac1 and Cdc42. To elucidate the role of IQGAP1 in cancer-cell adhesion, its expression was investigated in 4...

journal_title：International journal of cancer

authors： Takemoto H,Doki Y,Shiozaki H,Imamura H,Utsunomiya T,Miyata H,Yano M,Inoue M,Fujiwara Y,Monden M

更新日期：2001-03-15 00:00:00

abstract：:Two genome-wide association studies (GWAS) have identified 5p15.33 (TERT-CLPTM1L) as one of the susceptible regions for glioma in European background. A replication research of our group highlighted the association signals in the TERT gene of this region in a Chinese Han population. To comprehensively explore the regi...

journal_title：International journal of cancer

authors： Zhao Y,Chen G,Zhao Y,Song X,Chen H,Mao Y,Lu D

更新日期：2012-10-01 00:00:00

abstract：:The enzyme alpha1,3galactosyltransferase synthesizes the alphaGal epitope, a carbohydrate structure (Galalpha1,3Galbeta1,4GlcNAc-R), on glycoconjugates in lower mammals. The enzyme is absent in humans but large amounts of natural antibodies that recognize alphaGal epitopes are present in human serum. It is likely that...

journal_title：International journal of cancer

authors： Aubert M,Crotte C,Bernard JP,Lombardo D,Sadoulet MO,Mas E

更新日期：2003-12-20 00:00:00

abstract：:Allogeneic mixed leukocytes reaction has been reported to activate vast numbers of T lymphocytes and produce large amounts of type 1 cytokines that are linked to an initiation of antitumor immunity. Using poor immunogeneic B16-F10 and Lewis lung carcinoma (LLC) tumor model, we evaluated the effects of inactivated allo...

journal_title：International journal of cancer

authors： Su X,Guo S,Zhou C,Wang D,Ma W,Zhang S

更新日期：2009-03-01 00:00:00

abstract：:In order to clarify the frequency of p16 gene inactivation and its relationship with Rb expression, immunohistochemical analysis of p16 and Rb proteins was carried out on 82 paraffin-embedded sections of primary non-small cell lung cancers (NSCLCs). From immunohistochemical results, abnormal p16 expression was observe...

journal_title：International journal of cancer

authors： Kashiwabara K,Oyama T,Sano T,Fukuda T,Nakajima T

更新日期：1998-06-19 00:00:00

abstract：:To generate broad eating patterns, which could explain more adequately the breast cancer etiology, we conducted an exploratory factor analysis in Montevideo, Uruguay. The study included 442 newly diagnosed and microscopically confirmed cases with breast cancer and 442 hospitalized controls, with non-neoplastic disease...

journal_title：International journal of cancer

authors： Ronco AL,De Stefani E,Boffetta P,Deneo-Pellegrini H,Acosta G,Mendilaharsu M

更新日期：2006-10-01 00:00:00