Abstract:
:Cigarette smoking and alcohol consumption were examined as potential risk factors in a case-control study of primary liver cancer (PLC). A total of 165 PLC cases and 465 matched controls from several US hospitals were studied. A weak but statistically significant (p less than 0.05) dose-response relationship was observed between alcohol consumption and PLC in elderly females independent of other major risk factors (adjusted OR = 1.87 and 3.48 for 1-2 and greater than 3 drinks per day, respectively) and a similar trend was evident in elderly males. The risk for PLC was also elevated in elderly females who were current cigarette smokers (adjusted OR = 3.30). Our results suggest that alcohol consumption and cigarette smoking may have minor age- and sex-specific effects on the development of PLC, and underscore the need for further investigations to elucidate major PLC risk factors in US populations.
journal_name
Int J Cancerjournal_title
International journal of cancerauthors
Yu H,Harris RE,Kabat GC,Wynder ELdoi
10.1002/ijc.2910420304subject
Has Abstractpub_date
1988-09-15 00:00:00pages
325-8issue
3eissn
0020-7136issn
1097-0215journal_volume
42pub_type
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