Cigarette smoking, alcohol consumption and primary liver cancer: a case-control study in the USA.

Abstract:

:Cigarette smoking and alcohol consumption were examined as potential risk factors in a case-control study of primary liver cancer (PLC). A total of 165 PLC cases and 465 matched controls from several US hospitals were studied. A weak but statistically significant (p less than 0.05) dose-response relationship was observed between alcohol consumption and PLC in elderly females independent of other major risk factors (adjusted OR = 1.87 and 3.48 for 1-2 and greater than 3 drinks per day, respectively) and a similar trend was evident in elderly males. The risk for PLC was also elevated in elderly females who were current cigarette smokers (adjusted OR = 3.30). Our results suggest that alcohol consumption and cigarette smoking may have minor age- and sex-specific effects on the development of PLC, and underscore the need for further investigations to elucidate major PLC risk factors in US populations.

journal_name

Int J Cancer

authors

Yu H,Harris RE,Kabat GC,Wynder EL

doi

10.1002/ijc.2910420304

subject

Has Abstract

pub_date

1988-09-15 00:00:00

pages

325-8

issue

3

eissn

0020-7136

issn

1097-0215

journal_volume

42

pub_type

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