Abstract:
:Patients with ischemic stroke of unclear etiology are often screened for hypercoagulable syndromes or thrombophilias. These have been recognized to cause venous thrombosis, and include hereditary deficiencies of coagulation factors, genetic mutations, or acquired disorders. However, the majority of coagulation disorders are only rarely associated with ischemic stroke. The tests most commonly used to screen for thrombophilias comprise a complex array of assays that may be unreliable in various settings, including acute thrombosis, inflammation, and uses of medications such as anticoagulants. The diagnostic yield of thrombophilia tests in unselected stroke patients is very low, but may improve with careful selection of younger patients who have an otherwise undetermined cause of stroke or a history of venous thrombosis or multiple miscarriages. Various strategies have been developed that can guide the selection of patients (based on specific characteristics) and tests in the evaluation of thrombophilias. Although the diagnosis of thrombophilia aids in the potential explanation of stroke etiology, the best regimen for secondary prevention treatment for the majority of thrombophilias is still unknown.
journal_name
Curr Atheroscler Repjournal_title
Current atherosclerosis reportsauthors
Bushnell C,Goldstein LBdoi
10.1007/s11883-003-0052-8keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
291-8issue
4eissn
1523-3804issn
1534-6242journal_volume
5pub_type
杂志文章,评审abstract::The original version of this article contains errors in Table 3. "At least 1 project/publication in the year" and "> 1 publication per year" have been switched under the titles of "Clinical Track" and "Physician-Scientist track". ...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,已发布勘误
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2019-02-02 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2004-05-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2000-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2001-03-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2007-11-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2006-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2005-03-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2013-03-01 00:00:00
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更新日期:2014-05-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2019-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1999-11-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2014-03-01 00:00:00