Extending mathematical principles of reinforcement into the domain of behavioral pharmacology.

Abstract:

:Mathematical principles of reinforcement (MPR) attempts to integrate the empirical laws of reinforcement schedules that have accumulated over the decades. MPR is based on three principles: incentives excite behavior; there are temporal constraints on responding; and coupling of responses to reinforcers strengthens behavior [Behav. Brain Sci. 17 (1994) 105]. In the present paper MPR is extended into the domain of behavioral pharmacology, specifically to model the effects of D-amphetamine on operant behavior. In Experiment 1a, a five-component multiple fixed-ratio schedule was designed to generate behavioral baselines that were subsequently used to assess drug effect. In Experiments 1b and 1c, the quality and quantity of reinforcer were manipulated. The data generated by the three experiments were consistent with MPR. In Experiment 2, MPR was used to model the effects of D-amphetamine on rats responding under the five-component multiple fixed-ratio schedule. According to the model, the rate-decreasing effects of D-amphetamine were due primarily to motor disruption and secondarily to increased impulsivity; at the highest dosages, D-amphetamine also may have decreased the incentive value of food.

journal_name

Behav Processes

journal_title

Behavioural processes

authors

Reilly MP

doi

10.1016/s0376-6357(03)00027-5

keywords:

subject

Has Abstract

pub_date

2003-04-28 00:00:00

pages

75-88

issue

1-3

eissn

0376-6357

issn

1872-8308

pii

S0376635703000275

journal_volume

62

pub_type

杂志文章
  • Personality and physiological traits predict contest interactions in Kryptolebias marmoratus.

    abstract::Personality and physiological traits often have close relationships with dominance status, but the significance and/or direction of the relationships vary between studies. This study examines whether two personality traits (aggressiveness and boldness) and three physiological traits (testosterone and cortisol levels a...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2020.104079

    authors: Li CY,Tseng YC,Chen YJ,Yang Y,Hsu Y

    更新日期:2020-04-01 00:00:00

  • Effects of extended context discrimination training and context extinction on transfer of context dependency of conditioned flavor aversion.

    abstract::We trained rats in a context discrimination paradigm by pairing a sucrose solution with lithium chloride in one context (conditioning context) and simple exposure to the same fluid in a second (neutral) context to establish a context-dependent aversion to the conditioned fluid. We then investigated whether transfer of...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2013.12.014

    authors: Iguchi Y,Fukumoto K,Sawa K,Ishii K

    更新日期:2014-03-01 00:00:00

  • Windows.

    abstract::Some models of performance assume that behavior depends on environmental quantities (for example, rates of reinforcement) that are defined over intervals of fixed duration. Although such window models may serve as useful approximations, they are incompatible with well-known properties of behavior (for instance, sensit...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2005.02.007

    authors: Tonneau F

    更新日期:2005-05-31 00:00:00

  • Olfactory cues in host nest detection by the social parasite Polistes sulcifer (Hymenoptera, Vespidae).

    abstract::Sometimes the nests of the paper wasp Polistes dominulus are parasitized by the obligate social parasite Polistes sulcifer. It is not known how, in the spring, this parasite searches for established nests of its host species. This study investigates the capacity to detect the host nest by olfactory cues alone. In labo...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/0376-6357(95)00030-5

    authors: Cervo R,Bertocci F,Turillazzi S

    更新日期:1996-06-01 00:00:00

  • Circadian rhythms of locomotor activity in Drosophila.

    abstract::Drosophila is by far the most advanced model to understand the complex biochemical interactions upon which circadian clocks rely. Most of the genes that have been characterized so far were isolated through genetic screens using the locomotor activity rhythms of the adults as a circadian output. In addition, new techni...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/s0376-6357(03)00133-5

    authors: Klarsfeld A,Leloup JC,Rouyer F

    更新日期:2003-09-29 00:00:00

  • Being a weakling and surviving: Keep the fittest siblings close-by when eating.

    abstract::Weaklings serve as a buffer, allowing an increase in the overall prospect of offspring survival. Whereas birds are able to directly determine which offspring to invest in via selective feeding, multiparous mammals have fewer methods of excluding weaklings from milk provision. In pigs the maternal investment strategy i...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2016.10.010

    authors: Skok J

    更新日期:2016-12-01 00:00:00

  • Swarm intelligence in fish? The difficulty in demonstrating distributed and self-organised collective intelligence in (some) animal groups.

    abstract::Larger groups often have a greater ability to solve cognitive tasks compared to smaller ones or lone individuals. This is well established in social insects, navigating flocks of birds, and in groups of prey collectively vigilant for predators. Research in social insects has convincingly shown that improved cognitive ...

    journal_title:Behavioural processes

    pub_type: 杂志文章,评审

    doi:10.1016/j.beproc.2016.10.005

    authors: Ioannou CC

    更新日期:2017-08-01 00:00:00

  • Discrimination of shape and size sues by day-old chicks in two one-trial learning tasks.

    abstract::The ability of day-old chicks (Gallus gallus domesticus) to discriminate between the shape and size of beads was investigated in two one-trial tasks, taste avoidance and sickness-conditioned learning. Previous studies determined that color is a critical classification cue for conditioned stimuli in these tasks. In tas...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2015.11.019

    authors: Barber TA

    更新日期:2016-03-01 00:00:00

  • The acute social defeat stress and nest-building test paradigm: A potential new method to screen drugs for depressive-like symptoms.

    abstract::Psychosocial stress can cause mental conditions such as depression in humans. To develop drug therapies for the treatment of depression, it is necessary to use animal models of depression to screen drug candidates that exhibit anti-depressive effects. Unfortunately, the present methods of drug screening for antidepres...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2016.12.003

    authors: Otabi H,Goto T,Okayama T,Kohari D,Toyoda A

    更新日期:2017-02-01 00:00:00

  • Cooperation due to cultural norms, not individual reputation.

    abstract::Increased cooperation in groups that are allowed to communicate (engage in "cheap talk") has been attributed to reputation-building and to cultural norms or culturally normal behavior. We tested these two theories by exposing groups of undergraduates to a public-goods social dilemma. Five groups were permitted to comm...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2012.06.001

    authors: Baum WM,Paciotti B,Richerson P,Lubell M,McElreath R

    更新日期:2012-09-01 00:00:00

  • Activite operante et locomotrice chez des rats eleves dans des milieux differents.

    abstract::Male and female rats of the inbred August and Fischer strains were reared during two months after weaning either in a standard laboratory environment (controls) or in a more complex environment (treated animals). The performance of these rats was measured afterwards in an operant conditioning situation with positive r...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/0376-6357(77)90006-7

    authors: Will B,Ungerer A,Pallaud B,Ropartz P

    更新日期:1977-12-01 00:00:00

  • A propositional perspective on context effects in human associative learning.

    abstract::Propositional models of associative learning postulate that the behavioral impact of regularities in the presence of two events is mediated by the formation of propositions about the relation between these events. Because the mere statistical contingency between events often does not provide enough information to infe...

    journal_title:Behavioural processes

    pub_type: 杂志文章,评审

    doi:10.1016/j.beproc.2014.02.002

    authors: De Houwer J

    更新日期:2014-05-01 00:00:00

  • Behavioural comparison of human-animal (dog) and human-robot (AIBO) interactions.

    abstract::The behavioural analysis of human-robot interactions can help in developing socially interactive robots. The current study analyzes human-robot interaction with Theme software and the corresponding pattern detection algorithm. The method is based on the analysis of the temporal structure of the interactions by detecti...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2006.04.001

    authors: Kerepesi A,Kubinyi E,Jonsson GK,Magnusson MS,Miklósi A

    更新日期:2006-07-01 00:00:00

  • Integration of multiple memories in sensory preconditioning.

    abstract::The present study demonstrates that humans' response to a single stimulus (S1) is determined by what follows S1's associates. The experiment used a sensory preconditioning (SPC) design where S1 was associated with both S2 and S3 on separate trials before establishing relationships between these latter stimuli with an ...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2014.09.034

    authors: Craddock P,Renaux C,Lefèvre F,Nelson JB,Molet M

    更新日期:2014-10-01 00:00:00

  • Persistence of behaviours in the Forced Swim Test in 3xTg-AD mice at advanced stages of disease.

    abstract::Forced Swimming Test (FST) models behavioural despair in animals by loss of motivation to respond or the refusal to escape. The present study characterizes the behavioural responses of 12-month-old male 3xTg-AD mice in FST as compared to age-matched no-transgenic (NTg) mice. Paradoxical results were consistently found...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2014.05.001

    authors: Torres-Lista V,Giménez-Llort L

    更新日期:2014-07-01 00:00:00

  • Spatial navigation on the radial maze with trial-unique intramaze cues and restricted extramaze cues.

    abstract::We investigated the use of extramaze and intramaze cues on the eight-arm radial maze. The rats received daily training consisting of forced-choice visits to four baited arms, a retention interval, and the availability of all eight arms with baits available at arms that did not appear in the forced-choice phase. The ra...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/s0376-6357(03)00125-6

    authors: Babb SJ,Crystal JD

    更新日期:2003-08-29 00:00:00

  • Allosuckling in reindeer (Rangifer tarandus): milk-theft, mismothering or kin selection?

    abstract::Allosuckling, the suckling of offspring from females other than their own mother, has been reported in a number of mammalian species, including reindeer. The causes and function of this behaviour are still being investigated. We monitored 25 doe-calf pairs of semi-domestic reindeer Rangifer tarandus over 10 weeks to t...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2014.08.013

    authors: Engelhardt SC,Weladji RB,Holand Ø,de Rioja CM,Ehmann RK,Nieminen M

    更新日期:2014-09-01 00:00:00

  • Concurrent recall of serially learned visual discrimination problems in dwarf goats (Capra hircus).

    abstract::Studies of cognitive ability in farm animals are valuable, not only because they provide indicators of the commonality of comparative influence, but understanding farm animal cognition may also aid in management and treatment procedures. Here, eight dwarf goats (Capra hircus) learned a series of 10 visual four-choice ...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2008.07.004

    authors: Langbein J,Siebert K,Nuernberg G

    更新日期:2008-11-01 00:00:00

  • Stereotypies and suffering.

    abstract::Stereotypies often develop in environments that independent evidence shows cause poor welfare. Thus the development od stereotypies indicates that well-being has probably been poor, with the animal motivated to show a behaviour pattern that it could not perform normally or to completion. The continued performance of s...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/0376-6357(91)90013-P

    authors: Mason GJ

    更新日期:1991-12-01 00:00:00

  • Spatial learning in golden hamsters: Relationship between food-searching strategies and difficulty of the task.

    abstract::In an elevated maze consisting of three reconvergent radial arms, golden hamsters were tested with the same experimental rule: to choose each path without repeating any choice. However, variations of procedure concerning (a) the location of the reward in the maze, and (b) reinforcement contingencies, were introduced i...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/0376-6357(82)90007-9

    authors: Ammassari-Teule M,Durup H

    更新日期:1982-12-01 00:00:00

  • Order in the absence of an effect: Identifying rate-dependent relationships.

    abstract::The heterogeneity of group data can obscure a significant effect of an intervention due to differential baseline scores. Instead of discarding the seemingly heterogeneous response set, an orderly lawful relationship could be present. Rate dependence describes a pattern between a baseline and the change in that baselin...

    journal_title:Behavioural processes

    pub_type: 杂志文章,评审

    doi:10.1016/j.beproc.2016.03.012

    authors: Snider SE,Quisenberry AJ,Bickel WK

    更新日期:2016-06-01 00:00:00

  • Correlates between ear postures and emotional reactivity in a wild type mouse species.

    abstract::Facial expressions have been extensively used to assess emotions in humans and thus could be extended to other species that also display facial movements. In mice both painful and fearful situations have been associated with particular shifts in facial expressions. Like other species, mice frequently show a great inte...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2015.08.002

    authors: Lecorps B,Féron C

    更新日期:2015-11-01 00:00:00

  • Sexual segregation of forage patch use: Support for the social-factors and predation hypotheses.

    abstract::Nearly all species of sexually dimorphic ungulates sexually segregate. Several hypotheses have been proposed to explain this phenomenon, including the social-factors hypothesis (SFH) and the predation hypothesis (PH). Interestingly, previous studies have accepted and rejected each hypothesis within and across species ...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2017.01.003

    authors: Biggerstaff MT,Lashley MA,Chitwood MC,Moorman CE,DePerno CS

    更新日期:2017-03-01 00:00:00

  • Fish movement behaviour: variability within and between groups.

    abstract::The movement behaviour of mullet, Mugil cephalus (Linnaeus), an obligate schooling fish species, was recorded for individuals in small groups. Mean speeds and mean turning frequencies both declined significantly with increasing group size. Significant differences between groups were attributed to individual variation....

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/0376-6357(92)90015-6

    authors: Fitzsimmons SD,Warburton K

    更新日期:1992-01-01 00:00:00

  • Influences of food type on food-carrying behavior in rats (Rattus norvegicus).

    abstract::It is known that rats tend to eat a smaller/lighter piece of food at the food source but carry a larger/heavier one to the nest for consumption. This could be interpreted well in terms of the trade-off or motivational conflict between "feeding" and "risk avoidance", because eating food immediately satisfies feeding mo...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2005.02.028

    authors: Onuki Y,Kato K,Makino J

    更新日期:2005-09-30 00:00:00

  • The tendency for social submission predicts superior cognitive performance in previously isolated male mice.

    abstract::The imposition of subordination may negatively impact cognitive performance in common social settings (e.g., the classroom), and likewise, laboratory studies of animals indicate that the stress associated with social defeat can impair cognitive performance. It is less clear whether an animal's predisposition for socia...

    journal_title:Behavioural processes

    pub_type: 杂志文章,评审

    doi:10.1016/j.beproc.2016.07.011

    authors: Matzel LD,Kolata S,Light K,Sauce B

    更新日期:2017-01-01 00:00:00

  • Resurgence in Siamese fighting fish, Betta splendens.

    abstract::Resurgence of previously reinforced responding was investigated in male Siamese fighting fish (Betta splendens). Swimming through a ring produced 15-s mirror presentations according to, with different fish, either a fixed-ratio 1 or a variable-interval 60-s schedule of reinforcement. When responding was stable, a diff...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2014.01.004

    authors: da Silva SP,Cançado CR,Lattal KA

    更新日期:2014-03-01 00:00:00

  • I saw where you have been--The topography of human demonstration affects dogs' search patterns and perseverative errors.

    abstract::Performance in object search tasks is not only influenced by the subjects' object permanence ability. For example, ostensive cues of the human manipulating the target markedly affect dogs' choices. However, the interference between the target's location and the spatial cues of the human hiding the object is still unkn...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2016.02.005

    authors: Péter A,Topál J,Miklósi Á,Pongrácz P

    更新日期:2016-04-01 00:00:00

  • Avoiding traffic jams: Hitchhiking behavior as a strategy to reduce ant workers' traffic on the foraging trail.

    abstract::During foraging, thousands of leaf-cutting ant workers travel along high traffic foraging trails which, when narrow, reduce the leaf delivery rate due to the reduction in workers' travel-speed. On the other hand, high worker traffic promotes head-on encounters which are supposed to mediate worker task allocation and s...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2018.08.015

    authors: Hastenreiter IN,Lopes JFS,da Silva Camargo R,Forti LC

    更新日期:2018-12-01 00:00:00

  • Foraging devices as enrichment in captive walruses (Odobenus rosmarus).

    abstract::Stereotypies in captive animals are typically defined as repetitive, invariant behavioral patterns with no obvious goal or function. They are often attributed to boredom or fear and treated by introducing occupational stimuli. The present work on captive walruses examined the relationship between walrus stereotypies a...

    journal_title:Behavioural processes

    pub_type: 杂志文章

    doi:10.1016/j.beproc.2019.103943

    authors: Fernandez EJ,Timberlake W

    更新日期:2019-11-01 00:00:00