Abstract:
:The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6 pT m-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Kandori A,Oe H,Miyashita K,Date H,Yamada N,Naritomi H,Chiba Y,Murakami M,Miyashita T,Tsukada Kdoi
10.1007/BF02344215keywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
327-31issue
3eissn
0140-0118issn
1741-0444journal_volume
40pub_type
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