Abstract:
:The purpose of the present study is to analyze the prognostic factors of acute leukemia and to construct a decision model based on a causal relationship between the factors of this disease to assist medical specialists. In medical decisions, to reach effective, quick, and reliable results, there is a need for a simple decision-making model based on a specialist's self-assessment. It may help the medical team before final diagnosis by costly and time-consuming procedures such as bone marrow sampling and pathological test as well as provide an appropriate prognosis and diagnosis tool. Because of the complex and not the well-defined structure of medical data, the use of intelligent methods must be considered. For this purpose, first, a data-driven Bayesian network (BN) and Greedy algorithm are employed to determine causal relationships and probability between nodes using the real set of data. Then, these causal relationships will form based on the fuzzy cognitive map (FCM). Finally, according to scenarios defined, the results are analyzed. These analyses are also repeated for each type of acute leukemia including acute lymphocytic leukemia (ALL) and acute myelocytic leukemia (AML). Graphical abstract.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Jahangoshai Rezaee M,Sadatpour M,Ghanbari-Ghoushchi N,Fathi E,Alizadeh Adoi
10.1007/s11517-020-02267-wsubject
Has Abstractpub_date
2020-11-01 00:00:00pages
2845-2861issue
11eissn
0140-0118issn
1741-0444pii
10.1007/s11517-020-02267-wjournal_volume
58pub_type
杂志文章abstract::Modern pacemakers (implantable devices used for maintaining an appropriate heart rate in patients) can use an intracardiac ventricular impedance signal for physiological cardiac stimulation control. Intracardiac ventricular impedance from nine animal subjects is analysed and presented (seven sheep: 49.0 +/- 6.5 kg, si...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345448
更新日期:2002-09-01 00:00:00
abstract::A simple inertial measurement unit (IMU) incorporating rate gyroscopes and accelerometers has been tested to investigate the trunk kinematics during the sit-to-stand. It was affixed at trunk L5 level and used for sit-to-stand position and orientation reconstruction. The method was validated with standard optoelectroni...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0224-8
更新日期:2007-10-01 00:00:00
abstract::Detailed finite element (FE) models are used as promising tools to investigate traumatic brain injuries, although their accuracy is strongly dependent on the characterization of the mechanical behaviors of the different anatomic structures in the brain. In some cases, when the FE models require finer spatial resolutio...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-1891-3
更新日期:2019-03-01 00:00:00
abstract::A comparison of auditory and visual perception of scatterplots showed similar correlation estimation performance in both modalities. The present study replicated this experiment using electrotactile (electrocutaneous) presentation of scatterplots on the fingertips and abdomen, as well as visual presentation. The corre...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345967
更新日期:2005-03-01 00:00:00
abstract::Segmentation and classification of low-quality and noisy ultrasound images is challenging task. In this paper, a new approach is proposed for robust segmentation and classification of carotid artery ultrasound images and consequently, detecting cerebrovascular disease. The proposed technique consists of two phases, in...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1481-1
更新日期:2016-12-01 00:00:00
abstract::In the routine recording of magnetocardiograms (MCGs), it is necessary to underline the problem of noise cancellation. Source separation has often been suggested to solve this problem. In this paper, blind source separation (BSS), by means of singular value decomposition (SVD) and independent component analysis (ICA),...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0055-z
更新日期:2006-06-01 00:00:00
abstract::Calcific aortic valve disease (CAVD) is characterized by calcification accumulation and thickening of the aortic valve cusps, leading to stenosis. The importance of fluid flow shear stress in the initiation and regulation of CAVD progression is well known and has been studied recently using fluid-structure interaction...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1458-0
更新日期:2016-11-01 00:00:00
abstract::We introduce a novel method for an automatic classification of subjects to those with or without neuromuscular disorders. This method is based on multiscale entropy of recorded surface electromyograms (sEMGs) and support vector classification. The method was evaluated on a single-channel experimental sEMGs recorded fr...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0629-7
更新日期:2010-08-01 00:00:00
abstract::The objective of the present work was to develop automated methods for the compressed tracheal breathing sound analysis. Overnight tracheal breathing sound was recorded from ten apnoea patients. From each patient, three different types of tracheal sound deflection pattern, each of 10 min duration, were visually scored...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-008-0317-z
更新日期:2008-04-01 00:00:00
abstract::Bone mass and microarchitecture are the main determinants of bone strength. Three-dimensional micro-computed tomography has the potential to examine complete bones of small laboratory animals with very high resolution in a non-invasive way. In the presented work, the proximal part of the tibiae of hindlimb unloaded an...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347054
更新日期:2000-05-01 00:00:00
abstract::It is proposed that myo-electric signals can be used to augment conventional speech-recognition systems to improve their performance under acoustically noisy conditions (e.g. in an aircraft cockpit). A preliminary study is performed to ascertain the presence of speech information within myo-electric signals from facia...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345373
更新日期:2001-07-01 00:00:00
abstract::The fast hybrid operator splitting (HOS) and stable uniformization (UNI) methods have been proposed to save computation cost and enhance stability for Markov chain model in cardiac cell simulations. Moreover, Chen-Chen-Luo's quadratic adaptive algorithm (CCL) combined with HOS or UNI was used to improve the tradeoff b...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02220-x
更新日期:2020-09-01 00:00:00
abstract::The purpose of the study was to explore the application of artificial neural network model in the auxiliary diagnosis of lung cancer and compare the effects of back-propagation (BP) neural network with Fisher discrimination model for lung cancer screening by the combined detections of four biomarkers of p16, RASSF1A a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1585-7
更新日期:2017-08-01 00:00:00
abstract::Classification of cancerous genes from microarray data is an important research area in bioinformatics. Large amount of microarray data are available, but it is very costly to label them. This paper proposes an active learning model, a semi-supervised classification approach, to label the microarray data using which p...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02238-1
更新日期:2020-10-01 00:00:00
abstract::Fitting the measured bioimpedance spectroscopy (BIS) data to the Cole model and then extracting the Cole parameters is a common practice in BIS applications. The extracted Cole parameters then can be analysed as descriptors of tissue electrical properties. To have a better evaluation of physiological or pathological p...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-015-1355-y
更新日期:2016-04-01 00:00:00
abstract::Atrial fibrillation (AF) is the most common cardiac arrhythmia with episodes that may terminate spontaneously in the first stages of the disease. On the other hand, when the arrhythmia is not self-terminating, normal sinus rhythm (NSR) restoration use to be required to reduce the risk of stroke and improve cardiac out...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-008-0348-5
更新日期:2008-07-01 00:00:00
abstract::Two ways of rate control for diaphragm pacing are proposed. One is rate control using only the patients' body temperature (method I). The other is rate control by both the patients' heart rate and body temperature (method II). To test the effectiveness of these methods, a diaphragm pacemaker which can be controlled by...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446125
更新日期:1992-03-01 00:00:00
abstract::A computational model of the fluid dynamics of intraventricular flow was used to investigate the importance of the effects of flow disturbances existing within the left ventricle (LV) at the onset of diastole on a diastolic flow field. The simulation started with a quiescent flow state; it continued for a number of ca...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02350992
更新日期:2004-07-01 00:00:00
abstract::To evaluate the possibility of respiratory-volume measurement using photoplethysmography (PPG), PPG signals from 16 normal volunteers are collected, and the respiratory-induced intensity variations (RIIV) are digitally extracted. The RIIV signals are studied while respiratory volume is varied. Furthermore, respiratory...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513264
更新日期:1999-01-01 00:00:00
abstract::A previously proposed finite element model that considers geometric and material nonlinearities and the free boundary problems that occur at the catheter tip and in the annular zone around the lateral surface of the catheter was revised and was used to fit a power-law formula to predict backflow length during infusion...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-014-1187-1
更新日期:2014-10-01 00:00:00
abstract::Mammography is a widely used screening tool and is the gold standard for the early detection of breast cancer. The classification of breast masses into the benign and malignant categories is an important problem in the area of computer-aided diagnosis of breast cancer. A small dataset of 57 breast mass images, each wi...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0077-6
更新日期:2006-08-01 00:00:00
abstract::Transurethral resection of the prostate is the most common method of relieving urinary outflow obstruction secondary to prostatic enlargement. However, this procedure can be responsible for various complications, including irrigant-fluid absorption and blood loss, both of which are strongly dependent on operation dura...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510962
更新日期:1997-11-01 00:00:00
abstract::A bicuspid aortic valve (BAV) is a congenital cardiac disorder where the valve consists of only two cusps instead of three, as in a normal tricuspid valve (TAV). Although 97 % of BAVs include asymmetric cusps, little or no prior studies have investigated the blood flow through a three-dimensional BAV and root. The aim...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1055-4
更新日期:2013-08-01 00:00:00
abstract::Determination of the adequacy of dialysis is a routine but crucial procedure in patient evaluation. The total dialysis dose, expressed as Kt/V, has been widely recognised to be a major determinant of morbidity and mortality in haemodialysed patients. Many different factors influence the correct determination of Kt/V, ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02348080
更新日期:2003-07-01 00:00:00
abstract::A model which assesses the closed-loop interaction between heart period (HP) and arterial pressure (AP) variabilities and the influence of respiration on both is applied to evaluate the sources of low frequency (LF approximately 0.1 Hz) and high frequency (HF, respiratory rate approximately 0.25 Hz) in conscious dogs ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02518911
更新日期:1994-03-01 00:00:00
abstract::Automatic identification of landmarks in cephalometry is very important and useful for orthognathic surgery. A computerised automatic cephalometric analysis system (CACAS), based on image processing, is presented. For an original X-ray image, median filtering and histogram equalisation are used to improve image qualit...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345280
更新日期:2001-05-01 00:00:00
abstract::The vagus nerves convey both afferent and efferent information about autonomic activity related to cardiovascular functions. Those functions have been shown to change due to epileptic seizures, which suggests that ictal events might be detected via the vagus electroneurogram (VENG). In this study, we characterize the ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-011-0782-7
更新日期:2011-09-01 00:00:00
abstract::Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1499-4
更新日期:2017-02-01 00:00:00
abstract::To describe upper airway obstruction in patients with sleep apnea syndrome, the steady state solutions of a simple model of local pharyngeal obstruction were studied. Importantly, the present model embodies a series of two individualised elements, each having its own compliance, which enables the consideration, from a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510972
更新日期:1997-11-01 00:00:00
abstract::Pain control in conscious patients was investigated using a push-button, demand-driven supply of drugs. A fuzzy logic patient-controlled analgesia (PCA) algorithm was compared with a conventional algorithm, for alfentanil administration in extracorporeal shock-wave lithotripsy. The conventional PCA algorithm used an i...
journal_title:Medical & biological engineering & computing
pub_type: 临床试验,杂志文章
doi:10.1007/BF02347706
更新日期:2002-01-01 00:00:00