Multicentre study of fragrance allergy in Hungary. Immediate and late type reactions.

Abstract:

:The authors followed the frequency of fragrance contact sensitization in Hungary in a multicentre study in the years 1998 and 1999. A total of 3,604 patients were tested with fragrance mix (FM), and positive reactions were observed in 294 (8.2%). In 160 FM hypersensitive patients, the study was continued with patch testing of the mix constituents (cinnamic alcohol, cinnamic aldehyde, eugenol, amyl cinnamic aldehyde, hydroxycitronellal, geraniol, isoeugenol, oak moss absolute). Of the patients tested, 70.6% produced positive reactions to the constituents. FM contact sensitization was mainly observed in female patients (74.4%). The incidence of contact urticaria in FM hypersensitive patients was 6.1%. Simultaneous patch test trials of other environmental contact allergens, in both early and late evaluations, mainly confirmed hypersensitivity reactions to balsams. Female dominance of hypersensitivity reactions observed during testing the individual components of the mix was striking (82.4%). In positive skin reactions, cinnamic alcohol, isoeugenol and oak moss provoked skin symptoms most frequently. We also tested the 104 patients who produced negative reactions to FM with the constituent individual allergens, with 11.9% positive incidence. The clinical symptoms of the patients were above all manifest in the form of contact eczema, located on the hands, face, eyelids and axillae. With this study, the authors, members of the Hungarian Contact Dermatitis Research Group, call attention to one of the most frequent allergens in the environment.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Temesvári E,Németh I,Baló-Banga MJ,Husz S,Kohánka V,Somos Z,Judák R,Remenyik EV,Szegedi A,Nebenführer L,Mészáros C,Horváth A

doi

10.1034/j.1600-0536.2002.460602.x

keywords:

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

325-30

issue

6

eissn

0105-1873

issn

1600-0536

pii

cod460602

journal_volume

46

pub_type

杂志文章,多中心研究
  • Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic.

    abstract:BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13247

    authors: Bingham LJ,Tam MM,Palmer AM,Cahill JL,Nixon RL

    更新日期:2019-07-01 00:00:00

  • 2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen?

    abstract::Miconidin (2-methoxy-6-pentyl-1,4-dihydroxybenzene) and the allergen primin (2-methoxy-6-pentyl-1,4-benzoquinone) have been isolated from fresh unchopped plant material (leaves, stems and flowers together) of Primula obconica. Miconidin and primin were obtained in approximately equal amounts and their structures deter...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00507.x

    authors: Krebs M,Christensen LP

    更新日期:1995-08-01 00:00:00

  • Experimental skin deposition of chromium on the hands following handling of samples of leather and metal.

    abstract:BACKGROUND:Chromium is an important skin sensitizer. Exposure to it has been regulated in cement, and recently in leather. Studies on the deposition of chromium ions on the skin as a result of handling different chromium-containing materials are sparse, but could improve the risk assessment of contact sensitization and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12605

    authors: Bregnbak D,Thyssen JP,Jellesen MS,Zachariae C,Johansen JD

    更新日期:2016-08-01 00:00:00

  • Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce).

    abstract::In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05444.x

    authors: Friis B,Hjorth N,Vail JT Jr,Mitchell JC

    更新日期:1975-10-01 00:00:00

  • Nickel allergy--prevalence in a population of Swedish youths from patch test and questionnaire data.

    abstract:BACKGROUND:The prevalence of body piercing and orthodontic treatment has increased during recent decades. Such changes in lifestyle may influence the occurrence of nickel allergy. OBJECTIVES:The aim of this study was to describe the prevalence of nickel allergy in a Swedish youth population. METHODS:In a cross-sectio...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.01257.x

    authors: Fors R,Persson M,Bergström E,Stenlund H,Stymne B,Stenberg B

    更新日期:2008-02-01 00:00:00

  • Sensitization capacity of ethylenediamine in the guinea pig and induction of unresponsiveness.

    abstract::The sensitization capacity of ethylenediamine was examined by the guinea pig maximization test and compared with dinitrochlorobenzene. Ethylenediamine was found to be a potent sensitizer. An attempt at oral induction of unresponsiveness (tolerance) was unsuccessful with ethylenediamine and DNCB and the same negative r...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04881.x

    authors: Eriksen K

    更新日期:1979-09-01 00:00:00

  • Objective measurement of surfactant irritation by fiber optic spectroscopy.

    abstract::Erythema caused by occlusion of 3 concentrations of surfactant was quantified in vivo using a modified spectrophotometer. Standard chamber irritation test sites were evaluated objectively using the spectrophotometer and subjectively by trained observers. There was a good relationship between the instrumental and visua...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1988.tb02893.x

    authors: Crowe DM,Willard MS,Murahata RI,Aust LB,Gacula MC Jr

    更新日期:1988-09-01 00:00:00

  • Ten-year trends in contact allergy to formaldehyde and formaldehyde-releasers.

    abstract:BACKGROUND:Preservatives such as formaldehyde and formaldehyde-releasers are common causes of contact allergy. OBJECTIVES:To examine trends in contact allergy to formaldehyde and formaldehyde-releasers in patch tested patients in Denmark over a 10-year period (2007-2016), and to investigate relevant sources of formald...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13052

    authors: Fasth IM,Ulrich NH,Johansen JD

    更新日期:2018-11-01 00:00:00

  • Contact allergy trends in Sweden - a retrospective comparison of patch test data from 1992, 2000, and 2009.

    abstract:BACKGROUND:Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends. OBJECTIVES:The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish base...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12346

    authors: Fall S,Bruze M,Isaksson M,Lidén C,Matura M,Stenberg B,Lindberg M

    更新日期:2015-05-01 00:00:00

  • The nickel dose-response relationship by filaggrin genotype (FLG).

    abstract:BACKGROUND:On skin contact, nickel accumulates in the stratum corneum, where it is probably bound to proteins and amino acids. One probable contributor is filaggrin, which binds nickel avidly. Filaggrin gene (FLG) null mutations lead to a complete lack of filaggrin production from the affected allele, and have been ass...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12228

    authors: Ross-Hansen K,Johansen JD,Vølund A,Menné T,Thyssen JP

    更新日期:2014-07-01 00:00:00

  • A patch test closet.

    abstract::A way of adapting a treatment room for patch test purposes is described. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05362.x

    authors: Epstein E

    更新日期:1975-06-01 00:00:00

  • Contact allergy to lanolin: temporal changes in prevalence and association with atopic dermatitis.

    abstract:BACKGROUND:Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES:To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101)...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12872

    authors: Fransen M,Overgaard LEK,Johansen JD,Thyssen JP

    更新日期:2018-01-01 00:00:00

  • Contact dermatitis due to 2,2'-azobis(2-amidinopropane) dihydrochloride: an outbreak in production workers.

    abstract::2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) is an azo compound which has been used as a radical chain initiator. The purpose of this study was to confirm contact sensitivity to AAPH in individuals who were engaged in the production of AAPH, and presented with prolonged eczematous eruptions mainly on exposed a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1998.tb05803.x

    authors: Takiwaki H,Arase S,Nakayama H

    更新日期:1998-07-01 00:00:00

  • Prognosis of contact dermatitis in epoxy resin workers.

    abstract::Between January 1993 and February 2002, 40 of 1354 (3%) workers who attended a tertiary referral occupational dermatology clinic were diagnosed with allergic contact dermatitis (ACD) from epoxy resin systems (ER). 20 of these patients were followed up at least 2 years post-diagnosis to establish prognosis. Characteris...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2005.00542.x

    authors: Cahill J,Keegel T,Dharmage S,Nugriaty D,Nixon R

    更新日期:2005-03-01 00:00:00

  • Identification of pigments related to allergic tattoo reactions in 104 human skin biopsies.

    abstract:BACKGROUND:Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown. OBJECTIVES:Chemical analysis of human skin biopsies from chronic allergic reactions in red tattoos to identify culprit pigment(s) and metals. MATERIAL AND METHODS:One hundred four dermatome biopsies were analyze...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13423

    authors: Serup J,Hutton Carlsen K,Dommershausen N,Sepehri M,Hesse B,Seim C,Luch A,Schreiver I

    更新日期:2020-02-01 00:00:00

  • The preservative 2-(thiocyanomethylthio)benzothiazole: A potential allergen in leather products.

    abstract:BACKGROUND:Allergic contact dermatitis caused by leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole derivatives, and dyes, but also antimicrobials and antifungals, are involved. MATERIAL AND METHODS:Three female patients were referred to the Departments of Dermat...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13295

    authors: Herman A,Goossens A,Tennstedt D,Bergendorff O,Isaksson M,Mowitz M,Baeck M

    更新日期:2019-10-01 00:00:00

  • Rosin components identified in diapers.

    abstract::As part of the investigation of sources of exposure to rosin allergens, disposable diapers (napkins) common on the Swedish market were analyzed, using gas chromatography, to detect the main rosin compounds. Rosin components were detected in all diapers, the highest amounts in those from the 2 major producers. In these...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02169.x

    authors: Karlberg AT,Magnusson K

    更新日期:1996-03-01 00:00:00

  • A hand immersion test under laboratory-controlled usage conditions: the need for sensitive and controlled assessment methods.

    abstract::Exaggerated test conditions were frequently used to investigate the cutaneous tolerance of detergent products in the past. As the sensitivity of newly designed biometric methods is steadily improving, the trend towards more realistic test conditions should be encouraged. A hand immersion test under laboratory-controll...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0536.1999.tb06010.x

    authors: Paye M,Gomes G,Zerweck CR,Piérard GE,Grove GL

    更新日期:1999-03-01 00:00:00

  • Patch testing with fine fragrances: comparison with fragrance mix, balsam of Peru and a fragrance series.

    abstract::High frequencies of contact allergy to fragrance ingredients have been reported in recent years. Only approximately 70-80% are detected by fragrance allergens in the standard patch test series. This investigation compares the patch test reactions to fine fragrances with reactions to fragrance mix (FM), balsam of Peru ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2003.0264.x

    authors: Trattner A,David M

    更新日期:2003-12-01 00:00:00

  • Photopatch test method: influence of type of irradiation and value of day-7 reading.

    abstract::118 consecutive patients were photopatch tested with 5J UVA and 10mJ UVB. In addition, day 7 readings were taken. Testing with UVB and performing late readings conferred no advantage. The current recommendations of the British Photodermatology Group regarding photopatch testing remain the most recent guide to photopat...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2001.440502.x

    authors: Pollock B,Wilkinson SM

    更新日期:2001-05-01 00:00:00

  • Skin absorption from patch test systems.

    abstract::The development of topical drug products requires testing for skin toxicology reactions. A variety of patch test systems are available with which chemicals are applied to skin. The purpose of this study was to determine the skin absorption of paraphenylenediamine (PPDA) from a variety of such systems. [14C]-PPDA (1% p...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1987.tb02701.x

    authors: Kim HO,Wester RC,McMaster JA,Bucks DA,Maibach HI

    更新日期:1987-09-01 00:00:00

  • Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literature.

    abstract::Copolymers or heteropolymers are large molecules with high molecular weights (>1000 D). They have been underestimated for a long time as to their sensitizing capacities. Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still u...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.2006.00960.x

    authors: Quartier S,Garmyn M,Becart S,Goossens A

    更新日期:2006-11-01 00:00:00

  • Epidemiological, clinical and allergological observations on pompholyx.

    abstract::We have studied a group of 104 patients with pompholyx, to investigate the relationship between allergological factors and its etiopathogenesis. The following examinations were performed: blood sampling (routine tests and IgE levels), allergological tests (patch, prick, intradermal, and oral provovation tests with nic...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00862.x

    authors: Lodi A,Betti R,Chiarelli G,Urbani CE,Crosti C

    更新日期:1992-01-01 00:00:00

  • Lymphomatoid contact dermatitis due to ethylenediamine dihydrochloride.

    abstract::A case of contact sensitivity to ethylenediamine dihydrochloride is reported. The clinical and histological features were in keeping with early mycosis fungoides. The eruption cleared with avoidance of the allergen. Continued contact with the allergen was traced to its retention in a trouser pocket lining. The term "l...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1982.tb04135.x

    authors: Wall LM

    更新日期:1982-01-01 00:00:00

  • Development of hand eczema in junior hairdressers: an 8-year follow-up study.

    abstract::The development of hand eczema was evaluated in an 8-year follow-up study carried out in 51 junior hairdressers. Predisposing factors were investigated. Data were collected by use of a self-administered questionnaire: 74% response. None of the junior hairdressers presented with hand eczema at the start of the survey. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02193.x

    authors: Majoie IM,von Blomberg BM,Bruynzeel DP

    更新日期:1996-04-01 00:00:00

  • Cross-reactivity between thiurams.

    abstract::Retesting with an allergen at a site with previous allergic contact dermatitis has been shown to enhance reactivity. It has been suggested that retesting with a cross-reactive allergen will also induce hyperreactivity. Concurrent sensitization to more than 1 thiuram is common, but whether this is due to concomitant pr...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2006.00785.x

    authors: Lerbaek A,Menné T,Knudsen B

    更新日期:2006-03-01 00:00:00

  • Chemical analysis of monomers in epoxy resins based on bisphenols F and A.

    abstract::Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2004.00319.x

    authors: Pontén A,Zimerson E,Sörensen O,Bruze M

    更新日期:2004-05-01 00:00:00

  • Kathon CG: cosmetic allergy and patch test sensitization.

    abstract::Three cases of contact allergy to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are presented. In two patients, Kathon CG was contained in a moisturizing cream, and the third was sensitized by a diagnos...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1985.tb01057.x

    authors: de Groot AC,Liem DH,Weyland JW

    更新日期:1985-02-01 00:00:00

  • Allergic contact dermatitis to hydrolyzed wheat protein in a cosmetic cream.

    abstract::Hydrolyzed wheat protein is used as an additive in several cosmetic products. We present a case of contact allergy to hydrolyzed wheat protein found in a cosmetic cream and highlight this additive is a potential allergen. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.00977.x

    authors: Hann S,Hughes M,Stone N

    更新日期:2007-02-01 00:00:00

  • Release of thiurams and carbamates from rubber gloves.

    abstract::A method for quantitative determination of thiuram and carbamate derivatives released from rubber gloves into synthetic sweat is presented. The analysis was based upon determination of ester derivatives using gas-chromatography/mass spectrometry and isotope-dilution. The detection limit was 0.1 mg thiuram/carbamate in...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1993.tb03343.x

    authors: Knudsen BB,Larsen E,Egsgaard H,Menné T

    更新日期:1993-02-01 00:00:00