Regulation of Puralpha gene transcription: evidence for autoregulation of Puralpha promoter.

abstract：:An analysis of which component of lipopolysaccharides (LPS), the lipid or the polysaccharide (PS), is active in stimulating the murine granulopoietic system has been performed. LPS with different structures, isolated from different mutant strains of Salmonella and chemical degradation products of lipopolysaccharides h...

journal_title：Journal of cellular physiology

authors： Apte RN,Galanos C,Pluznik DH

更新日期：1976-01-01 00:00:00

abstract：:We have previously shown that mitochondrial activity is an important regulator of myoblast differentiation, partly through processes targeting myogenin expression. Here, we investigated the possible involvement of c-myc in these processes. Inhibition of mitochondrial activity by chloramphenicol abrogated the decrease ...

journal_title：Journal of cellular physiology

authors： Seyer P,Grandemange S,Busson M,Carazo A,Gamaléri F,Pessemesse L,Casas F,Cabello G,Wrutniak-Cabello C

更新日期：2006-04-01 00:00:00

abstract：:Glioblastoma (GB) is the most common cancer in the brain and with an increasing incidence. Despite major advances in the field, there is no curative therapy for GB to date. Many solid tumors, including GB, experienced metabolic reprogramming in order to sustain uncontrolled proliferation, hypoxic conditions, and angio...

journal_title：Journal of cellular physiology

authors： Benedetti E,d'Angelo M,Ammazzalorso A,Gravina GL,Laezza C,Antonosante A,Panella G,Cinque B,Cristiano L,Dhez AC,Astarita C,Galzio R,Cifone MG,Ippoliti R,Amoroso R,Di Cesare E,Giordano A,Cimini A

更新日期：2017-06-01 00:00:00

abstract：:Thioredoxin reductase (TrxR) is a flavoprotein that contains a C-terminal penultimate selenocysteine (Sec) and has an ability to reduce thioredoxin (Trx), which regulates the activity of NF-kappa B. To date, three TrxR isozymes, TrxR1, TrxR2, and TrxR3, have been identified. In the present study, we found that among t...

journal_title：Journal of cellular physiology

authors： Sakurai A,Yuasa K,Shoji Y,Himeno S,Tsujimoto M,Kunimoto M,Imura N,Hara S

更新日期：2004-01-01 00:00:00

abstract：:Experiments were carried out to test the hypothesis that cell spreading and phagocytosis are similar cell responses to different-sized substrata. The following morphological and biochemical studies provided evidence for this supposition. Cells phagocytosed 1.09-micron and 5.7-micron latex beads, but were unable to com...

journal_title：Journal of cellular physiology

authors： Grinnell F

更新日期：1984-04-01 00:00:00

abstract：:Membrane vesicles derived principally from the plasma membrane and endoplasmic reticulum of mouse 3T3 cells transformed by Simian virus 40 take up alpha-aminoisobutyric acid (AIB) and phosphate (Pi). When NaCl is added simultaneously with AIB or Pi, uptake rises two- to three-times above the equilibrium to accumulate ...

journal_title：Journal of cellular physiology

authors： Nilsen-Hamilton M,Hamilton RT

更新日期：1976-12-01 00:00:00

abstract：:The p53 protein directly regulates the expression of the WAF1 (wild-type p53-activated fragment 1) protein which is a cyclin-dependent kinase inhibitor (CDK1). DNA damaging agents such as ionizing or UV radiation, and some chemical agents induce WAF1 in wild-type p53 containing cells, thereby halting cell cycle progre...

journal_title：Journal of cellular physiology

authors： Shiohara M,Akashi M,Gombart AF,Yang R,Koeffler HP

更新日期：1996-03-01 00:00:00

abstract：:Sterol regulatory element binding protein 1 (SREBP-1) is well-known as the master regulator of lipogenesis in rodents. Acyl-CoA synthetase short-chain family member 2 (ACSS2) plays a key role in lipogenesis by synthesizing acetyl-CoA from acetate for lipogenesis. ATP citrate lyase (ACLY) catalyzes the conversion of ci...

journal_title：Journal of cellular physiology

authors： Xu H,Luo J,Ma G,Zhang X,Yao D,Li M,Loor JJ

更新日期：2018-02-01 00:00:00

abstract：:Subcellular organellles from livers of rats three days prenatal to 50 weeks postnatal were separated on sucrose gradients. The peroxisomes had a constant density of 1.243 g/ml throughout the life of the animal. The density of the mitochondria changed from about 1.236 g/ml at birth to a constant value of 1.200 g/ml aft...

journal_title：Journal of cellular physiology

authors： Krahling JB,Gee R,Gauger JA,Tolbert NE

更新日期：1979-12-01 00:00:00

abstract：:Prostate cancer (PCa) is one of the most common cancers and the fifth most common reason for cancer deaths in the males. Surgical castration combined with androgen deprivation therapy, antiandrogens, and androgen synthesis inhibitors is the current therapeutic modalities for PCa. These strategies inhibit androgen synt...

journal_title：Journal of cellular physiology

authors： Rezaei S,Mahjoubin Tehran M,Sahebkar A,Jalili A,Aghaee-Bakhtiari SH

更新日期：2020-04-01 00:00:00

abstract：:Hydrocortisone and dexamethasone produced a time-dependent increase [125I]epidermal growth factor [( 125I]EGF) binding in primary cultures of isolated rat hepatocytes. Maximally effective doses of glucocorticoids resulted in a 70-100% increase in binding. The effect was similar when hepatocytes were maintained on coll...

journal_title：Journal of cellular physiology

authors： Lin Q,Blaisdell J,O'Keefe E,Earp HS

更新日期：1984-06-01 00:00:00

abstract：:Damage-associated molecular patterns, including mitochondrial DNA (mtDNA) are released during hemorrhage resulting in the development of endotheliopathy. Tranexamic acid (TXA), an antifibrinolytic drug used in hemorrhaging patients, enhances their survival despite the lack of a comprehensive understanding of its cellu...

journal_title：Journal of cellular physiology

authors： Prudovsky I,Carter D,Kacer D,Palmeri M,Soul T,Kumpel C,Pyburn K,Barrett K,DeMambro V,Alexandrov I,Brandina I,Kramer R,Rappold J

更新日期：2019-11-01 00:00:00

abstract：:Adipose differentiation of 3T3-F442A cells in surface cultures depends on adipogenic factor present in the culture medium. We found that after stimulation with adipogenic serum, 3T3-F442A cell underwent a burst of DNA synthesis before adipose conversion was manifested by an augmented lipogenic enzyme activity. In diff...

journal_title：Journal of cellular physiology

authors： Kuri-Harcuch W,Marsch-Moreno M

更新日期：1983-01-01 00:00:00

abstract：:Alpha-2-glycoprotein 1, zinc-binding (AZGP1), known as zinc-alpha-2-glycoprotein (ZAG), is a multifunctional secretory glycoprotein and relevant to cancer metastasis. Little is known regarding the underlying mechanisms of AZGP1 in prostate cancer (PCa). In the present study, we report that AZGP1 is an androgen-respons...

journal_title：Journal of cellular physiology

authors： Cao R,Ke M,Wu Q,Tian Q,Liu L,Dai Z,Lu S,Liu P

更新日期：2019-08-01 00:00:00

abstract：:The effect of hypoxia on 3T3-L1 cell differentiation was examined in confluent cultures incubated with differentiation medium (DM) followed by incubation in growth medium (GM). Control cultures remained in GM throughout the incubation period. Eight days after the incubation, cells were assessed either for changes in m...

journal_title：Journal of cellular physiology

authors： Sahai A,Patel MS,Zavosh AS,Tannen RL

更新日期：1994-07-01 00:00:00

abstract：:Interleukin (IL)-18 is a pro-inflammatory cytokine belonging to the IL-1 family, first identified for its interferon-γ-inducing properties. IL-18 regulates both T helper (Th) 1 and Th2 responses. It acts synergistically with IL-12 in the Th1 paradigm, whereas with IL-2 and without IL-12 it can induce Th2 cytokine prod...

journal_title：Journal of cellular physiology

authors： Vecchié A,Bonaventura A,Toldo S,Dagna L,Dinarello CA,Abbate A

更新日期：2021-03-01 00:00:00

abstract：:We have previously reported that interferon-alpha (IFNalpha) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNalpha and EGF could modulate cell remodeling in our experimental conditions. We...

journal_title：Journal of cellular physiology

authors： Boccellino M,Giuberti G,Quagliuolo L,Marra M,D'Alessandro AM,Fujita H,Giovane A,Abbruzzese A,Caraglia M

更新日期：2004-10-01 00:00:00

abstract：:Hyperinsulinemia is a likely cause of the increased cancer incidence and mortality in diabetic patients, but its role is difficult to define in vivo. Previous in vitro studies testing the mitogenic potential of insulin and its analogs provided incomplete and sometimes contradictory results. To better evaluate cancer c...

journal_title：Journal of cellular physiology

authors： Sciacca L,Cassarino MF,Genua M,Vigneri P,Giovanna Pennisi M,Malandrino P,Squatrito S,Pezzino V,Vigneri R

更新日期：2014-11-01 00:00:00

abstract：:A new system for studying growth of normal human mammary epithelial cells in an in vivo environment using athymic nude mice is described. Human mammary epithelial cells dissociated from reduction mammoplasty specimens were embedded within collagen gels and subsequently transplanted subcutaneously into nude mice. Histo...

journal_title：Journal of cellular physiology

authors： Popnikolov NK,Yang J,Guzman RC,Swanson SM,Thordarson G,Collins G,Talamantes F,Nandi S

更新日期：1995-04-01 00:00:00

abstract：:The Belgrade rat has a hypochromic, microcytic anemia inherited as an autosomal recessive mutation. Although transferrin binds normally to reticulocytes and internalizes normally, iron accumulation into cells and heme is much slower than normal. We have investigated the role of the transferrin cycle in this mutant by ...

journal_title：Journal of cellular physiology

authors： Garrick LM,Gniecko K,Hoke JE,al-Nakeeb A,Ponka P,Garrick MD

更新日期：1991-03-01 00:00:00

abstract：:Vitamin D3 metabolites regulate the differentiation of chondrocytes isolated from the growth zone or resting zone of rat costochondral cartilage. Since some of the direct membrane effects of vitamin D metabolites are nongenomic, we hypothesized that protein kinase C (PKC) plays a role in signal transduction for these ...

journal_title：Journal of cellular physiology

authors： Sylvia VL,Schwartz Z,Schuman L,Morgan RT,Mackey S,Gomez R,Boyan BD

更新日期：1993-11-01 00:00:00

abstract：:Human skin fibroblasts contracted fibrin gels in a time- and cell-dependent manner. Under optimal conditions, gel contraction amounted to more than 50% in 2 hr. Fibronectin did not promote contraction, and fibrinolysis was not required for contraction, although gels contracted without serum or aprotinin were lysed. Be...

journal_title：Journal of cellular physiology

authors： Tuan TL,Grinnell F

更新日期：1989-09-01 00:00:00

abstract：:Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development and tumorigenesis was evaluated by in-situ hybridization on mouse ma...

journal_title：Journal of cellular physiology

authors： Szabova L,Yamada SS,Birkedal-Hansen H,Holmbeck K

更新日期：2005-10-01 00:00:00

abstract：:Exposure to D-allose has been demonstrated to lead to decreased 2-deoxy-D-glucose (2-DG) and 3-0-methyl-D-glucose transport in the V79 Chinese hamster lung fibroblast cell line. The effect of D-allose 1) was maximal after 4 hours exposure to the cells; 2) was optimal between 2.77 and 5.55 mM D-allose; and 3) led to a ...

journal_title：Journal of cellular physiology

authors： Germinario RJ,Kristof A,Chang Z,Manuel S

更新日期：1990-11-01 00:00:00

abstract：:We examined the behavior of the transcription factor Max during retrograde neuronal degeneration of retinal ganglion cells. Using immunohistochemistry, we found a progressive redistribution of full-length Max from the nucleus to the cytoplasm and dendrites of the ganglion cells following axon damage. Then, the axotomi...

journal_title：Journal of cellular physiology

authors： Petrs-Silva H,de Freitas FG,Linden R,Chiarini LB

更新日期：2004-02-01 00:00:00

abstract：:Receptors for urokinase (uPA) and plasminogen provide a mechanism to direct the cellular activation of plasminogen. The regulation of these receptors is important for several macrophage functions. In these studies, the effect of transforming growth factor-beta 1 (TGF-beta 1) on uPA, uPA receptor, and plasminogen recep...

journal_title：Journal of cellular physiology

authors： Falcone DJ,McCaffrey TA,Mathew J,McAdam K,Borth W

更新日期：1995-08-01 00:00:00

abstract：:The growth factors FGF and vasopressin were found to have only a transient effect on confluent quiescent monolayers of Swiss 3T3 cells. Whether measured as cumulative entry into S-phase by autoradiography, or as cell division by time-lapse filming, the elevated rate of cell proliferation was maintained only over 10-15...

journal_title：Journal of cellular physiology

authors： Richmond KM,Riddle PN,Brooks RF

更新日期：1984-12-01 00:00:00

abstract：:A monoclonal antibody (mAb), 2E12, against the neural cell adhesion molecule L1 recognized the 200 kDa component of L1. The epitope of L1 reacting with mAb 2E12 was localized in its carbohydrate chain, judging from the results of experiments on glycopeptidase F treatment. The physiological effect of adding mAbL1 (2E12...

journal_title：Journal of cellular physiology

authors： Asou H

更新日期：1992-11-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related death worldwide. About 1.8 million new cases were reported in 2018. Accordingly, there is an urgent need for development of effective strategies to lower the mortality and morbidity originated from this malignancy. MicroRNAs ...

journal_title：Journal of cellular physiology

authors： Anvarnia A,Mohaddes-Gharamaleki F,Asadi M,Akbari M,Yousefi B,Shanehbandi D

更新日期：2019-12-01 00:00:00

abstract：:The SV40 transformed murine macrophage cell line, BAC1, proliferates in response to the colony stimulating factor, CSF-1 (Schwarzbaum et al., J. Immunol., 132:1158, 1984). In order to obtain a cell line suitable for biochemical and genetic studies of CSF-1 signal transduction, clones of BAC1 were established. Clones r...

journal_title：Journal of cellular physiology

authors： Morgan C,Pollard JW,Stanley ER

更新日期：1987-03-01 00:00:00