Uptake of alpha-aminoisobutyric acid and phosphate by membrane vesicles derived from growing and quiescent fibroblasts.

abstract：:Five-week-old female mice supplemented with estradiol and progesterone are able to respond to epidermal growth factor (EGF) and EGF-like growth factors (alpha-transforming growth factor [alpha-TGF] and crude mammary-derived growth factor) with local lobuloalveolar development when these growth factors are directly int...

journal_title：Journal of cellular physiology

authors： Vonderhaar BK

更新日期：1987-09-01 00:00:00

abstract：:The Na+ pump (Na+, K+-ATPase) has been implicated in the regulation of many cellular functions, including cell volume regulation. The effects of inhibiting Na+ pump activity on cell volume and taurine efflux were evaluated in the human neuroblastoma cell line CHP-100. Cell volume changes monitored with the Coulter Mul...

journal_title：Journal of cellular physiology

authors： Basavappa S,Mobasheri A,Errington R,Huang CC,Al-Adawi S,Ellory JC

更新日期：1998-02-01 00:00:00

abstract：:Induction of vascular smooth muscle (VSM) alpha-actin mRNA expression during cytodifferentiation of mouse BC3H1 myogenic cells coincides with the accumulation of cell surface- and extracellular matrix-associated sulfated proteoglycans. Inhibition of proteoglycan biosynthesis in myogenic cells using an artificial beta-...

journal_title：Journal of cellular physiology

authors： Lee SH,Yan H,Reeser JC,Dillman JM,Strauch AR

更新日期：1995-07-01 00:00:00

abstract：:With the long-range goals of elucidating the biochemical genetics and the phenotypic expression, both in vitro and in vivo, of mutator strains of mammalian cells, we have isolated and partially characterized a series of drug-resistant mutants from a subline a feeder-dependent parental mouse teratocarcinoma line (PSA-1...

journal_title：Journal of cellular physiology

authors： Aizawa S,Loeb LA,Martin GM

更新日期：1983-04-01 00:00:00

abstract：:The purpose of this study was to delineate the traffic patterns of EGF and EGF receptors (EGFR) in primary cultured acinar epithelial cells from rabbit lacrimal glands. Uptake of [(125)I]-EGF exhibited saturable and non-saturable, temperature-dependent components, suggesting both receptor-mediated and fluid phase endo...

journal_title：Journal of cellular physiology

authors： Xie J,Qian L,Wang Y,Rose CM,Yang T,Nakamura T,Hamm-Alvarez SF,Mircheff AK

更新日期：2004-04-01 00:00:00

abstract：:Migration and proliferation of smooth muscle cells (SMCs) are key events during neointimal formation in pathological conditions of vessels. Tenascin-C (TNC) is upregulated in the developing neointima of lesions. We evaluated the effects of TNC on responses of SMCs against platelet-derived growth factor (PDGF) stimulat...

journal_title：Journal of cellular physiology

authors： Ishigaki T,Imanaka-Yoshida K,Shimojo N,Matsushima S,Taki W,Yoshida T

更新日期：2011-10-01 00:00:00

abstract：:Hepatic sinusoidal Ito cells have the capacity to produce interstitial collagen types I and III as well as other matrix proteins and may be involved in hepatic fibrogenesis. Transforming growth factor beta (TGF beta) responsiveness was evaluated during in vitro cell culture, since increasing evidence suggests that thi...

journal_title：Journal of cellular physiology

authors： Davis BH

更新日期：1988-09-01 00:00:00

abstract：:Tumor suppressor pRb2/p130 gene belongs to the retinoblastoma (Rb) gene family, which also includes pRb/p105 and pRb/p107. The members of the Rb gene family have attracted a great deal of interest because of their essential role in regulating cell cycle and, consequently, cell proliferation. This mini review discusses...

journal_title：Journal of cellular physiology

authors： Giordano A,Rossi A,Romano G,Bagella L

更新日期：2007-11-01 00:00:00

abstract：:The aim of the yearly National Congress of the Italian Society of Virology (SIV) is to promote the discussion between senior and younger researchers to improve the knowledge and scientific collaboration among the various areas of Virology. The invited and selected lecturers of the fourth National Congress of SIV cover...

journal_title：Journal of cellular physiology

authors： Salata C,Parolin C,Palù G

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:MiR-152 has been reported as a tumor suppressor microRNA that is downregulated in a number of cancers, including colorectal cancer (CRC). A recent study suggested that miR-152 could be one of the key regulators of CRC. The aim of this study is to investigate the role of miR-152 in CRC and its mechanisms. ME...

journal_title：Journal of cellular physiology

authors： Ghazanchaei A,Mansoori B,Mohammadi A,Biglari A,Baradaran B

更新日期：2018-01-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:Synthesis of alpha- and beta-globin RNA in DMSO-induced Friend's erythroleukemia cells and synthesis of immunoglobulin gamma- and kappa-chain RNA, total RNA, 5S RNA, and tRNA in mouse myeloma cells (MPC-11) was inhibited by gamma-irradiation. For all RNA species, synthesis decreased nearly exponentially as a function ...

journal_title：Journal of cellular physiology

authors： Rodi CP,Sauerbier W

更新日期：1989-11-01 00:00:00

abstract：:Calreticulin is an ER calcium-storage protein, which influences gene expression and cell adhesion. In this study, we analysed the differences in adhesive properties of calreticulin under- and overexpressing fibroblasts in relation to the calmodulin- and calcium/calmodulin-dependent kinase II (CaMK II)-dependent signal...

journal_title：Journal of cellular physiology

authors： Szabo E,Papp S,Opas M

更新日期：2007-10-01 00:00:00

abstract：:We have analyzed the functional and morphological effects of corticosteroid hormones in a SV40-transformed rabbit cortical-ascending-limb (CAL) cell line (RC.SV2, Vandewalle et al., 1989) having mineralocorticoid (MR) and glucocorticoid (GR) receptors (Rafestin-Oblin et al., 1993). Both aldosterone and dexamethasone (...

journal_title：Journal of cellular physiology

authors： Vandewalle A,Rafestin-Oblin ME,Hagege J,Géniteau-Legendre M,Cassingéna R,Ronco PM

更新日期：1993-08-01 00:00:00

abstract：:In a recent publication, Heubusch et al. (J Cell. Physiol, 122:266-272, 1985) reported changes of erythrocyte volume measured by the Coulter counter technique over a wide range of osmolalities (160 to 3000 m0sm). Their results showed a partially hindered, nonlinear response, in contrast to classical observations made ...

journal_title：Journal of cellular physiology

authors： Massaldi HA,Richieri GV,Mel HC

更新日期：1986-06-01 00:00:00

abstract：:Four cell lines, named nonparenchymal 11 (NP11), NP26, NP31, and NP32, were established from sinusoidal endothelial cells (SECs) of rat liver. They still retained expression of receptors for vascular endothelial growth factor (VEGF), Fit-1, and kinase domain-containing receptor (KDR). NP31 and NP32 turned out to be in...

journal_title：Journal of cellular physiology

authors： Maru Y,Yamaguchi S,Takahashi T,Ueno H,Shibuya M

更新日期：1998-08-01 00:00:00

abstract：:Mitochondrial transcription factor A (TFAM) is responsible for stability, maintenance, and transcriptional control of mitochondrial DNA (mtDNA). We have studied the expression and distribution of TFAM in the gametes and preimplantation embryos of the domestic pig (Sus scrofa). We hypothesized that TFAM is not present ...

journal_title：Journal of cellular physiology

authors： Antelman J,Manandhar G,Yi YJ,Li R,Whitworth KM,Sutovsky M,Agca C,Prather RS,Sutovsky P

更新日期：2008-11-01 00:00:00

abstract：:Extracellular ATP and other nucleotides induce autocrine and/or paracrine purinergic signalling via activation of the P2 receptors on the cell surface, which represents one of the most common signalling mechanisms. Mesenchymal stem cells (MSC) are a type of multipotent adult stem cells that have many promising applica...

journal_title：Journal of cellular physiology

authors： Jiang LH,Hao Y,Mousawi F,Peng H,Yang X

更新日期：2017-02-01 00:00:00

abstract：:Aberrant activation of the HGF/c-Met signalling pathway is reported to be associated with cell proliferation, progression, and metastasis features of several tumor types, including cervical cancer, suggesting that it may be of potential value as a novel therapeutic target. Furthermore, HPV-positive patients had a high...

journal_title：Journal of cellular physiology

authors： Boromand N,Hasanzadeh M,ShahidSales S,Farazestanian M,Gharib M,Fiuji H,Behboodi N,Ghobadi N,Hassanian SM,Ferns GA,Avan A

更新日期：2018-06-01 00:00:00

abstract：:The role of diacylglycerol (DAG) in hormonal induction of S phase was investigated in primary cultures of rat hepatocytes. In this model, several agonists that bind to G protein-coupled receptors act as comitogens when added to the cells soon after plating (i.e., in Go/early Gl phase), while the cells are most respons...

journal_title：Journal of cellular physiology

authors： Dajani OF,Sandnes D,Melien O,Rezvani F,Nilssen LS,Thoresen GH,Christoffersen T

更新日期：1999-08-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF), a potent mediator of endothelial proliferation and migration, has an important role also in brain edema formation during hypoxia and ischemia. VEGF binds to the tyrosine kinase receptors Flt-1 and Flk-1. Yet, their relative importance for hypoxia-induced hyperpermeability is ...

journal_title：Journal of cellular physiology

authors： Vogel C,Bauer A,Wiesnet M,Preissner KT,Schaper W,Marti HH,Fischer S

更新日期：2007-07-01 00:00:00

abstract：:Sodium butyrate (6 mM) blocks the resumption of the cell division cycle in serum-deprived chemically transformed Balb/c-3T3 mouse fibroblasts (BP-A31). The inhibition of G1 progression by sodium butyrate is not restricted to a specific mitogenic signaling pathway and is equally effective when tetradecanoyl phorbol ace...

journal_title：Journal of cellular physiology

authors： Charollais RH,Buquet C,Mester J

更新日期：1990-10-01 00:00:00

abstract：:BAG3 protein, a member of the BAG co-chaperones family, sustains cell survival in a variety of normal and neoplastic cell types, via its interaction with a variety of partners, such as the heat shock protein (HSP) 70, Bcl-2, Raf-1 and others. Expression of BAG3 is induced by some stressful stimuli, such as heat shock,...

journal_title：Journal of cellular physiology

authors： Du ZX,Zhang HY,Meng X,Gao YY,Zou RL,Liu BQ,Guan Y,Wang HQ

更新日期：2009-03-01 00:00:00

abstract：:Nerve-evoked contractile activity in skeletal muscle regulates transcript and protein levels of many metabolic genes in a coordinate fashion, including the muscle isozyme of glycogen phosphorylase (MGP). Cellular signaling mechanisms mediating the activity-dependent modulation of MGP transcript levels were investigate...

journal_title：Journal of cellular physiology

authors： Vali S,Carlsen R,Pessah I,Gorin F

更新日期：2000-11-01 00:00:00

abstract：:We have studied the transcriptional activity, steady-state mRNA levels, and steady-state protein levels of the c-myc and transferrin receptor (TfR) genes in murine M1 myeloid leukemia cells arrested in G1 phase of the cell cycle by different methods. When cells are growth-arrested by density inhibition, a technique th...

journal_title：Journal of cellular physiology

authors： Neckers LM,Tsuda H,Weiss E,Pluznik DH

更新日期：1988-05-01 00:00:00

abstract：:The cells responsible for the long-term in vitro generation of murine mast cells have been examined. Sequential analysis of all colony types obtained from cultures of spleen or bone marrow cells showed that only colonies derived from multipotential cells (mixed-erythroid colonies) or mast cell progenitors, contained c...

journal_title：Journal of cellular physiology

authors： Li CL,Johnson GR

更新日期：1984-10-01 00:00:00

abstract：:Adipogenesis, a physiological process initiated with the committed preadipocytes expressing adipocyte-specific genes and terminated in mature, differentiated and functional adipocytes, mainly involved with energy homeostasis. Abnormal distribution-changes and dysfunctions in adipogenesis may lead to complex physiopath...

journal_title：Journal of cellular physiology

authors： Yi X,Wu P,Liu J,Gong Y,Xu X,Li W

更新日期：2019-11-01 00:00:00

abstract：:Proteolytic cleavage of extracellular matrix (ECM) and disruption of tissue architecture are fundamental features of tumor cell invasion. The proteolytic activity is focused in close proximity to the tumor cells. Here, we describe the possibility to quantify local proteolytic activity in the microenvironment of larger...

journal_title：Journal of cellular physiology

authors： Ludwig T,Püttmann S,Bertram H,Tatenhorst L,Paulus W,Oberleithner H,Senner V

更新日期：2005-03-01 00:00:00

abstract：:Ganoderma lucidum immunomodulatory protein (FIP-glu) is an active ingredient with potential immunoregulatory functions. The study was conducted to explore the immunomodulatory activities of recombinant FIP-glu (rFIP-glu) and its possible mechanism in macrophage RAW264.7 cells. In vitro assays of biological activity in...

journal_title：Journal of cellular physiology

authors： Li QZ,Chang YZ,He ZM,Chen L,Zhou XW

更新日期：2019-12-01 00:00:00

abstract：:Myocardium infarction is one of the most deathly cardiovascular diseases. It is characterized by myocardium ischemia as a result of nutrients depletion and hypoxia. The cell can respond to this injury by autophagy or apoptosis, which determines the evolution and possible recovery of the myocardium infarction. Lipids p...

journal_title：Journal of cellular physiology

authors： Sousa B,Melo T,Campos A,Moreira AS,Maciel E,Domingues P,Carvalho RP,Rodrigues TR,Girão H,Domingues MR

更新日期：2016-10-01 00:00:00