Identification of the potential key genes for adipogenesis from human mesenchymal stem cells by RNA-Seq.

abstract：:We have previously shown that mitochondrial activity is an important regulator of myoblast differentiation, partly through processes targeting myogenin expression. Here, we investigated the possible involvement of c-myc in these processes. Inhibition of mitochondrial activity by chloramphenicol abrogated the decrease ...

journal_title：Journal of cellular physiology

authors： Seyer P,Grandemange S,Busson M,Carazo A,Gamaléri F,Pessemesse L,Casas F,Cabello G,Wrutniak-Cabello C

更新日期：2006-04-01 00:00:00

abstract：:TRB3 (a mammalian homolog of Drosophila) is emerging as an important player in the regulation of insulin signaling. TRB3 can directly bind to Ser/Thr protein kinase Akt, the major downstream kinase of insulin signaling. Conversely, physical exercise has been linked to improved glucose homeostasis and enhanced insulin ...

journal_title：Journal of cellular physiology

authors： Lima AF,Ropelle ER,Pauli JR,Cintra DE,Frederico MJ,Pinho RA,Velloso LA,De Souza CT

更新日期：2009-10-01 00:00:00

abstract：:The expression of laminin, a major constituent of endometrial cell basement membranes, is increased during differentiation of human endometrial stromal cells (decidualization). To determine whether laminin plays a role in decidualization, we studied the effects of laminin substrate on the synthesis and release of prol...

journal_title：Journal of cellular physiology

authors： Brar AK,Frank GR,Richards RG,Meyer AJ,Kessler CA,Cedars MI,Klein DJ,Handwerger S

更新日期：1995-04-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:Fibroblast growth factor-2 (FGF-2) stimulates periodontal regeneration by a broad spectrum of effects on periodontal ligament (PDL) cells, such as proliferation, migration, and production of extracellular matrix. A critical factor in the success of periodontal regeneration is the rapid resolution of inflammatory respo...

journal_title：Journal of cellular physiology

authors： Fujihara C,Kanai Y,Masumoto R,Kitagaki J,Matsumoto M,Yamada S,Kajikawa T,Murakami S

更新日期：2019-05-01 00:00:00

abstract：:Incubation of isolated rat soleus and EDL muscles in the presence of 10 mM leucine resulted in a decreased proteolytic rate as measured by the release of tyrosine into the incubation medium. The effect of this branched-chain amino acid (BCAA) is associated with a decreased activity of the lysosomal proteases and a dec...

journal_title：Journal of cellular physiology

authors： Busquets S,Alvarez B,Llovera M,Agell N,López-Soriano FJ,Argilés JM

更新日期：2000-09-01 00:00:00

abstract：:We have modified a method (Gilles et al: Anal. Biochem., 159:109-113, 1986) for measuring cell number, that is based on the binding of crystal violet to cell nuclei and used it to assay effects of various glycosaminoglycans on growth of human lung fibroblasts. The procedure was modified by growing cells in microcultur...

journal_title：Journal of cellular physiology

authors： Westergren-Thorsson G,Onnervik PO,Fransson LA,Malmström A

更新日期：1991-06-01 00:00:00

abstract：:We recently reported that the growth of normal rat pleural mesothelial cells (RPMCs) is inhibited by conditioned media from either in vivo or in vitro transformed RPMCs. In this study we report that the growth of normal RPMCs is inhibited by epidermal growth factor (EGF). This was demonstrated by using three methods o...

journal_title：Journal of cellular physiology

authors： Van der Meeren A,Levy F,Renier A,Katz A,Jaurand MC

更新日期：1990-07-01 00:00:00

abstract：:Homeostasis of proteins involved in contractility of individual cardiomyocytes and those coupling adjacent cells is of critical importance as any abnormalities in cardiac electrical conduction may result in cardiac irregular activity and heart failure. Bcl2-associated athanogene 3 (BAG3) is a stress-induced protein wh...

journal_title：Journal of cellular physiology

authors： Tahrir FG,Gordon J,Feldman AM,Cheung J,Khalili K,Mohseni Ahooyi T

更新日期：2019-08-01 00:00:00

abstract：:Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening perio...

journal_title：Journal of cellular physiology

authors： Bush H,Shodell M

更新日期：1977-03-01 00:00:00

abstract：:Alpha-2-glycoprotein 1, zinc-binding (AZGP1), known as zinc-alpha-2-glycoprotein (ZAG), is a multifunctional secretory glycoprotein and relevant to cancer metastasis. Little is known regarding the underlying mechanisms of AZGP1 in prostate cancer (PCa). In the present study, we report that AZGP1 is an androgen-respons...

journal_title：Journal of cellular physiology

authors： Cao R,Ke M,Wu Q,Tian Q,Liu L,Dai Z,Lu S,Liu P

更新日期：2019-08-01 00:00:00

abstract：:The function of microRNA-27a (miR-27a) on synovial angiogenesis and chondrocyte apoptosis in rats with knee osteoarthritis (KOA) by targeting PLK2 is explored in this present study. The rat model of KOA was conducted by anterior cruciate ligament transection. Rats were injected with miR-27a mimics, mimics NC, pcDNA3.1...

journal_title：Journal of cellular physiology

authors： Liu W,Zha Z,Wang H

更新日期：2019-12-01 00:00:00

abstract：:The mechanisms by which mature myeloid cells are released from the bone marrow into the peripheral blood are not clearly understood. Glycosylation is likely to play an important role, as has been shown in the homing of lymphocytes to lymph nodes and of neutrophils to inflamed endothelia. Cell surface sialylation is an...

journal_title：Journal of cellular physiology

authors： Le Marer N,Skacel PO

更新日期：1999-06-01 00:00:00

abstract：:Cardiac fibroblast (CF) differentiation to myofibroblasts expressing α-smooth muscle actin (α-SMA) plays a key role in cardiac fibrosis. Therefore, a study of the mechanism regulating α-SMA expression is a means to understanding the mechanism of fibroblast differentiation and cardiac fibrosis. Previous studies have sh...

journal_title：Journal of cellular physiology

authors： He Y,Ling S,Sun Y,Sheng Z,Chen Z,Pan X,Ma G

更新日期：2019-05-01 00:00:00

abstract：:Conditions have been established under which the antizyme of ornithine decarboxylase (E.C. 4.1.1.17, L-ornithine carboxy-lyase, ODC) a non-competitive protein inhibitor of ODC, can be detected in cells in response to as little as 10(-7) M putrescine. The maintenance of intracellular antizyme activity depends upon the ...

journal_title：Journal of cellular physiology

authors： Heller JS,Canellakis ES

更新日期：1981-05-01 00:00:00

abstract：:Endoplasmic reticulum (ER) stress, a common cellular stress response, is closely related to the activation of autophagy that is an important and evolutionarily conserved mechanism for maintaining cellular homeostasis. Autophagy induced by ER stress mainly includes the ER stress-mediated autophagy and ER-phagy. The ER ...

journal_title：Journal of cellular physiology

authors： Song S,Tan J,Miao Y,Zhang Q

更新日期：2018-05-01 00:00:00

abstract：:Myeloid cells, including granulocytes and monocyte/macrophages, are important in disease-associated inflammatory reactions. These cells come from a common progenitor, the promyelocyte. The human promyelocytic cell line, HL-60, can be induced to terminally differentiate into granulocytes or monocyte/ macrophages in a c...

journal_title：Journal of cellular physiology

authors： Brent LH,Rubenstein B,Gong QH,Wieland SJ

更新日期：1996-07-01 00:00:00

abstract：:CHFR acts as a tumor suppressor gene, which is frequently inactivated caused by its promoter hypermethylation in various solid tumors. Although a recent study showed that CHFR hypermethylation was a frequent event in acute myeloid leukemia (AML) and correlated with adverse clinical outcome, herein, we found that CHFR ...

journal_title：Journal of cellular physiology

authors： Zhou JD,Zhang TJ,Li XX,Ma JC,Guo H,Wen XM,Yao DM,Zhang W,Lin J,Qian J

更新日期：2018-06-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSC) can ameliorate ischemic injury of various tissues. However, the molecular mechanisms involved remain to be clarified. In this study, we intend to investigate the effects of BMSC-derived conditioned medium (BMSC-CM) on hypoxia/reoxygenation (H/R)-induced injury of H9c2 myocardi...

journal_title：Journal of cellular physiology

authors： Li X,Xie X,Yu Z,Chen Y,Qu G,Yu H,Luo B,Lei Y,Li Y

更新日期：2019-08-01 00:00:00

abstract：:Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is caused by a dysregulated and aberrant immune response to exposed environmental factors in genetically susceptible individuals. Despite huge efforts in determining the molecular pathogenesis of IBD, an increasing worldwide incidence ...

journal_title：Journal of cellular physiology

authors： Moein S,Vaghari-Tabari M,Qujeq D,Majidinia M,Nabavi SM,Yousefi B

更新日期：2019-04-01 00:00:00

abstract：:Ischemic stroke (IS), which is characterized by high morbidity, disability, and mortality, is recognized as a major cerebrovascular disease. MicroRNA-31 (miR-31) was reported to participate in the progression of brain disease. The present study was conducted in order to investigate the effect of miR-31 on oxidative st...

journal_title：Journal of cellular physiology

authors： Li J,Lv H,Che YQ

更新日期：2020-03-01 00:00:00

abstract：:The protein tyrosine kinase pp125FAK (focal adhesion kinase, or FAK) is expressed by a variety of cell types and has been implicated in integrin-mediated signaling events. We explored the potential functions of FAK by expressing it de novo in a cell type lacking FAK. We showed previously that cultured human macrophage...

journal_title：Journal of cellular physiology

authors： De Nichilo MO,Katz BZ,O'Connell B,Yamada KM

更新日期：1999-02-01 00:00:00

abstract：:The bone marrow landscape consists of specialized and stem/progenitor cells, which coordinate important tissue-related and systemic physiological features. Within the marrow cavity, stem/progenitor and differentiated hematopoietic and skeletal cells congregate into dynamic functional assemblies throughout specific ana...

journal_title：Journal of cellular physiology

authors： Agas D,Sabbieti MG

更新日期：2021-01-25 00:00:00

abstract：:The aim of this study was to determine the effects and molecular mechanism of blue light emitting diode (LED) in tumor cells. A migration and invasion assay for the metastatic behavior of mouse colon cancer CT-26 and human fibrosarcoma HT-1080 cells was performed. Cancer cell migration-related proteins were identified...

journal_title：Journal of cellular physiology

authors： Oh PS,Kim HS,Kim EM,Hwang H,Ryu HH,Lim S,Sohn MH,Jeong HJ

更新日期：2017-12-01 00:00:00

abstract：:p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apoptosis by interferi...

journal_title：Journal of cellular physiology

authors： Sheikh MS,Fornace AJ Jr

更新日期：2000-02-01 00:00:00

abstract：:Type 1 diabetes is inhibited in diabetes-prone BioBreeding (BBdp) rats fed a low-antigen hydrolyzed casein (HC) diet. In cereal-fed BBdp rats, islet expansion is defective accompanied by a futile upregulation of islet neogenesis without increased islet mass, due to a subtle blockage in islet cell cycle. We hypothesize...

journal_title：Journal of cellular physiology

authors： Wang GS,Kauri LM,Patrick C,Bareggi M,Rosenberg L,Scott FW

更新日期：2010-08-01 00:00:00

abstract：:Using the Madin Darby canine kidney (MDCK) cell "calcium switch," we have previously demonstrated that, as MDCK cells establish contact and ultimately form tight junctions, there are marked global and localized changes in intracellular calcium at the sites of cell-cell contact (Nigam et al., 1992, Proc. Natl. Acad. Sc...

journal_title：Journal of cellular physiology

authors： Stuart RO,Sun A,Panichas M,Hebert SC,Brenner BM,Nigam SK

更新日期：1994-06-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:Interest in the role of the insulin-like growth factor (IGF) axis in growth control and carcinogenesis has recently been increased by the finding of elevated serum insulin-like growth factor I (IGF-I) levels in association with three of the most prevalent cancers in the United States: prostate cancer, colorectal cance...

journal_title：Journal of cellular physiology

authors： Grimberg A,Cohen P

更新日期：2000-04-01 00:00:00

abstract：:Erythropoietin (EPO), the key hormone for erythropoiesis, also increases nitric oxide (NO) bioavailability in endothelial cells (ECs), yet the definitive mechanisms are not fully understood. Increasing evidence has demonstrated that β common receptor (βCR) plays a crucial role in EPO-mediated non-hematopoietic effects...

journal_title：Journal of cellular physiology

authors： Su KH,Shyue SK,Kou YR,Ching LC,Chiang AN,Yu YB,Chen CY,Pan CC,Lee TS

更新日期：2011-12-01 00:00:00