Abstract:
:Following sciatic nerve injury sympathetic invasion and basket formation is seen in dorsal root ganglia. We examined whether this phenomenon occurs in trigeminal ganglion (TG) following axotomy (IOAx) or chronic constriction injury to the infraorbital nerve (IOCCI). The IOCCI rats developed hyperresponsiveness to pinprick stimulation consistent with this model and the IOAx rats remained hyporesponsive for most of the study period. Immunocytochemistry employing antibodies to tyrosine hydroxylase showed no sympathetic invasion or basket formation 2 and 7 weeks post surgery. This study confirms previous work that found no sympathetic invasion of TG following injury, and shows that this finding is unaffected by the presence or absence of nerve injury induced hyperresponsiveness.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Benoliel R,Eliav E,Tal Mdoi
10.1016/s0304-3940(00)01681-5keywords:
subject
Has Abstractpub_date
2001-01-19 00:00:00pages
151-4issue
3eissn
0304-3940issn
1872-7972pii
S0304394000016815journal_volume
297pub_type
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