Correlates of the "don't know" response to questions about snoring.

abstract：:To investigate the annual decline of lung function in subjects with self-reported asthma, we analyzed data from a longitudinal epidemiologic study. The Copenhagen City Heart Study. The study sample consisted of 10,952 subjects (4,824 men), 20 to 90 yr of age, randomly selected from the city of Copenhagen followed over...

journal_title：American journal of respiratory and critical care medicine

authors： Ulrik CS,Lange P

更新日期：1994-09-01 00:00:00

abstract：RATIONALE:Inhaled corticosteroids are commonly prescribed to patients with chronic obstructive pulmonary disease (COPD). OBJECTIVES:To examine whether these medications might be associated with an excess risk of pneumonia. METHODS:We conducted a nested case-control study within a cohort of patients with COPD from Que...

journal_title：American journal of respiratory and critical care medicine

authors： Ernst P,Gonzalez AV,Brassard P,Suissa S

更新日期：2007-07-15 00:00:00

abstract：:It has been nearly a century since the first suggestion that a soluble factor in plasma or serum might be responsible for the symptoms of allergic disease and asthma, and more than 30 yr since immunoglobulin E (IgE) was identified as the key molecule in mediating what are now described as type 1 hypersensitivity react...

journal_title：American journal of respiratory and critical care medicine

authors： Platts-Mills TA

更新日期：2001-10-15 00:00:00

abstract：RATIONALE:Pulmonary infection in cystic fibrosis (CF) is polymicrobial and it is possible that anaerobic bacteria, not detected by routine aerobic culture methods, reside within infected anaerobic airway mucus. OBJECTIVES:To determine whether anaerobic bacteria are present in the sputum of patients with CF. METHODS:S...

journal_title：American journal of respiratory and critical care medicine

authors： Tunney MM,Field TR,Moriarty TF,Patrick S,Doering G,Muhlebach MS,Wolfgang MC,Boucher R,Gilpin DF,McDowell A,Elborn JS

更新日期：2008-05-01 00:00:00

abstract：RATIONALE:Daily azithromycin decreases acute exacerbations of chronic obstructive pulmonary disease (AECOPD), but long-term side effects are unknown. OBJECTIVES:To identify the types of exacerbations most likely to be reduced and clinical subgroups most likely to benefit from azithromycin, 250 mg daily, added to usual...

journal_title：American journal of respiratory and critical care medicine

authors： Han MK,Tayob N,Murray S,Dransfield MT,Washko G,Scanlon PD,Criner GJ,Casaburi R,Connett J,Lazarus SC,Albert R,Woodruff P,Martinez FJ

更新日期：2014-06-15 00:00:00

abstract：:To investigate the utility of testing all tuberculosis patients for HIV infection in Los Angeles, we prospectively evaluated 183 hospitalized patients with acid-fast smear-positive tuberculosis who gave no history of HIV infection. HIV serologic testing was performed, and the presence of risk factors for HIV infection...

journal_title：American journal of respiratory and critical care medicine

authors： Barnes PF,Silva C,Otaya M

更新日期：1996-04-01 00:00:00

abstract：:The last century experienced remarkable advances in the classification, diagnosis, and understanding of the pathogenesis of the interstitial lung diseases. Technological advances, particularly physiologic testing, lung imaging studies, bronchoalveolar lavage, surgical lung biopsy, and histopathologic assessment, impro...

journal_title：American journal of respiratory and critical care medicine

authors： King TE Jr

更新日期：2005-08-01 00:00:00

abstract：RATIONALE:The contribution of interferon-gamma release assays (IGRAs) to appropriate risk stratification of active tuberculosis suspects has not been studied. OBJECTIVES:To determine whether the addition of quantitative IGRA results to a prediction model incorporating clinical criteria improves risk stratification of ...

journal_title：American journal of respiratory and critical care medicine

authors： Metcalfe JZ,Cattamanchi A,Vittinghoff E,Ho C,Grinsdale J,Hopewell PC,Kawamura LM,Nahid P

更新日期：2010-01-01 00:00:00

abstract：:Collapsibility of the active pharynx, where active contraction of the upper airway muscles is evident, was previously reported to be higher in children with obstructive sleep apnea (OSA) than in those with primary snoring during sleep. Contribution of neuromuscular and anatomic factors to the increased collapsibility,...

journal_title：American journal of respiratory and critical care medicine

authors： Isono S,Shimada A,Utsugi M,Konno A,Nishino T

更新日期：1998-04-01 00:00:00

abstract：:The Child Health Questionnaire (CHQ-PF50) is one of several recent efforts to gauge pediatric, health-related quality of life from the patient's (or parent's) perspective. Although tested extensively with healthy children, more information is needed about CHQ performance among children with chronic conditions such as ...

journal_title：American journal of respiratory and critical care medicine

authors： Asmussen L,Olson LM,Grant EN,Landgraf JM,Fagan J,Weiss KB

更新日期：2000-10-01 00:00:00

abstract：:This study was carried out to determine if the bronchoconstrictive effect of cigarette smoke (CS) is enhanced when airway hyperresponsiveness is induced by ovalbumin (Ova) sensitization, and if so, whether an increase in endogenously released tachykinins is involved. The bronchoconstrictive effects of an acute CS inha...

journal_title：American journal of respiratory and critical care medicine

authors： Wu ZX,Zhou D,Chen G,Lee LY

更新日期：2000-01-01 00:00:00

abstract：:To investigate patterns of testing for human immunodeficiency virus (HIV) infection in tuberculosis patients, we obtained data from the tuberculosis registry and from medical records of 500 tuberculosis patients in Los Angeles County. Sixty-three percent of tuberculosis patients were tested for HIV infection, and mult...

journal_title：American journal of respiratory and critical care medicine

authors： Asch SM,London AS,Barnes PF,Gelberg L

更新日期：1997-01-01 00:00:00

abstract：RATIONALE:An objective and simple prognostic model for patients with pulmonary embolism could be helpful in guiding initial intensity of treatment. OBJECTIVES:To develop a clinical prediction rule that accurately classifies patients with pulmonary embolism into categories of increasing risk of mortality and other adve...

journal_title：American journal of respiratory and critical care medicine

authors： Aujesky D,Obrosky DS,Stone RA,Auble TE,Perrier A,Cornuz J,Roy PM,Fine MJ

更新日期：2005-10-15 00:00:00

abstract：RATIONALE:Community-acquired pneumonia (CAP) accounts for a major proportion of intensive care unit (ICU) admissions for respiratory failure and sepsis. Diagnostic uncertainty complicates case management, which may delay appropriate cause-specific treatment. OBJECTIVES:To characterize the blood genomic response in pat...

journal_title：American journal of respiratory and critical care medicine

authors： Scicluna BP,Klein Klouwenberg PM,van Vught LA,Wiewel MA,Ong DS,Zwinderman AH,Franitza M,Toliat MR,Nürnberg P,Hoogendijk AJ,Horn J,Cremer OL,Schultz MJ,Bonten MJ,van der Poll T

更新日期：2015-10-01 00:00:00

abstract：:Comparison of the risk-benefit profiles of different inhaled glucocorticoids has been limited by inadequate information about the dose-response relationships for efficacy relative to side effects. Fluticasone propionate (FP) is twice as effective as budesonide (BUD), but the potency ratio of FP:BUD with respect to sup...

journal_title：American journal of respiratory and critical care medicine

authors： Donnelly R,Williams KM,Baker AB,Badcock CA,Day RO,Seale JP

更新日期：1997-12-01 00:00:00

abstract：RATIONALE:Activin-A is up-regulated in various respiratory disorders. However, its precise role in pulmonary pathophysiology has not been adequately substantiated in vivo. OBJECTIVES:To investigate in vivo the consequences of dysregulated Activin-A expression in the lung and identify key Activin-A-induced processes th...

journal_title：American journal of respiratory and critical care medicine

authors： Apostolou E,Stavropoulos A,Sountoulidis A,Xirakia C,Giaglis S,Protopapadakis E,Ritis K,Mentzelopoulos S,Pasternack A,Foster M,Ritvos O,Tzelepis GE,Andreakos E,Sideras P

更新日期：2012-02-15 00:00:00

abstract：:The aim of this study was to evaluate the effect of two body positions (supine and semirecumbency) on the dynamics of gastroesophageal reflux (GER) in 15 patients requiring mechanical ventilation and having a nasogastric tube in place. Samples of gastric contents, pharyngeal and bronchial secretions, and blood were ob...

journal_title：American journal of respiratory and critical care medicine

authors： Orozco-Levi M,Torres A,Ferrer M,Piera C,el-Ebiary M,de la Bellacasa JP,Rodriguez-Roisin R

更新日期：1995-10-01 00:00:00

abstract：RATIONALE:In cystic fibrosis, abnormal glucose tolerance is associated with decreased lung function and worsened outcomes. Translational evidence indicates that abnormal glucose tolerance may begin in early life. OBJECTIVES:To determine whether very young children with cystic fibrosis have increased abnormal glucose t...

journal_title：American journal of respiratory and critical care medicine

authors： Yi Y,Norris AW,Wang K,Sun X,Uc A,Moran A,Engelhardt JF,Ode KL

更新日期：2016-10-15 00:00:00

abstract：:Several modalities of ventilatory support have been proposed to gradually withdraw patients from mechanical ventilation, but their respective effects on the outcome of weaning from mechanical ventilation are not known. We conducted a randomized trial in three intensive care units in mechanically ventilated patients wh...

journal_title：American journal of respiratory and critical care medicine

authors： Brochard L,Rauss A,Benito S,Conti G,Mancebo J,Rekik N,Gasparetto A,Lemaire F

更新日期：1994-10-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is traditionally diagnosed using overnight polysomnography. Decision rules may provide an alternative to polysomnography. A consecutive series of patients referred to a tertiary sleep center underwent prospective evaluation with the upper airway physical examination protocol, followed by ...

journal_title：American journal of respiratory and critical care medicine

authors： Tsai WH,Remmers JE,Brant R,Flemons WW,Davies J,Macarthur C

更新日期：2003-05-15 00:00:00

abstract：RATIONALE:In a high-tuberculosis (TB) incidence area of Cape Town, South Africa, there is a very high rate of unexplained recurrent TB. The incidence of new bacteriologically confirmed disease in the area is 313 per 100,000 individuals. OBJECTIVE:To estimate the rate of recurrent TB attributable to reinfection after s...

journal_title：American journal of respiratory and critical care medicine

authors： Verver S,Warren RM,Beyers N,Richardson M,van der Spuy GD,Borgdorff MW,Enarson DA,Behr MA,van Helden PD

更新日期：2005-06-15 00:00:00

abstract：:During dynamic hyperinflation, the ventilatory pump is facing increased demand because it must overcome the intrinsic positive end-expiratory pressure (PEEPi) and decreased capacity since it must operate at a dynamically increased end-expiratory lung volume (EELV). The aim of this study was to evaluate the relative pr...

journal_title：American journal of respiratory and critical care medicine

authors： Yan S,Kayser B

更新日期：1997-08-01 00:00:00

abstract：RATIONALE:The sympathetic nervous system has been reported to be activated in pulmonary arterial hypertension (PAH). OBJECTIVES:We investigated the prognostic significance of muscle sympathetic nervous system activity (MSNA) in PAH. METHODS:Thirty-two patients with PAH were included in the study and underwent a measu...

journal_title：American journal of respiratory and critical care medicine

authors： Ciarka A,Doan V,Velez-Roa S,Naeije R,van de Borne P

更新日期：2010-06-01 00:00:00

abstract：:The German reunification offers a unique opportunity to study the impact of environmental factors on the development of childhood respiratory and allergic disorders in ethnically similar populations. We investigated the prevalence of asthma, hay fever, atopy, and bronchial hyperresponsiveness (BHR) in 9- to 11-year ol...

journal_title：American journal of respiratory and critical care medicine

authors： von Mutius E,Martinez FD,Fritzsch C,Nicolai T,Roell G,Thiemann HH

更新日期：1994-02-01 00:00:00

abstract：:In pleural infection, medical treatment failure (chest-tube drainage and antibiotics) requires surgery and increases mortality. It would be helpful to predict which patients will fail this approach. We examined clinical predictors in 85 consecutive patients with pleural infection receiving chest drainage and intrapleu...

journal_title：American journal of respiratory and critical care medicine

authors： Davies CW,Kearney SE,Gleeson FV,Davies RJ

更新日期：1999-11-01 00:00:00

abstract：RATIONALE:Little is known about the long-term outcomes and costs of survivors of acute respiratory distress syndrome (ARDS). OBJECTIVES:To describe functional and quality of life outcomes, health care use, and costs of survivors of ARDS 2 yr after intensive care unit (ICU) discharge. METHODS:We recruited a cohort of ...

journal_title：American journal of respiratory and critical care medicine

authors： Cheung AM,Tansey CM,Tomlinson G,Diaz-Granados N,Matté A,Barr A,Mehta S,Mazer CD,Guest CB,Stewart TE,Al-Saidi F,Cooper AB,Cook D,Slutsky AS,Herridge MS

更新日期：2006-09-01 00:00:00

abstract：RATIONALE:Endobronchial ultrasound (EBUS) and electromagnetic navigation bronchoscopy (ENB) have increased the diagnostic yield of bronchoscopic diagnosis of peripheral lung lesions. However, the role of combining these modalities to overcome each individual technique's limitations and, consequently, to further increas...

journal_title：American journal of respiratory and critical care medicine

authors： Eberhardt R,Anantham D,Ernst A,Feller-Kopman D,Herth F

更新日期：2007-07-01 00:00:00

abstract：RATIONALE:Pulmonary complications (PCs) cause significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HCT). Shifts in gut microbiota have been linked to HCT outcomes; however, their effect on PCs is unknown. OBJECTIVES:To investigate whether changes in gut microbiota are associate...

journal_title：American journal of respiratory and critical care medicine

authors： Harris B,Morjaria SM,Littmann ER,Geyer AI,Stover DE,Barker JN,Giralt SA,Taur Y,Pamer EG

更新日期：2016-08-15 00:00:00

abstract：RATIONALE:The prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmonary disease. Recent studies suggest that vitamin D deficiency is associated with reduced lung function. The relationship between vitamin D deficiency and lung fu...

journal_title：American journal of respiratory and critical care medicine

authors： Zosky GR,Berry LJ,Elliot JG,James AL,Gorman S,Hart PH

更新日期：2011-05-15 00:00:00

abstract：:Silicosis is characterized by fibrosing nodular lesions that may eventually develop into progressive massive fibrosis (PMF). Cytokines (interleukin-1beta [IL-1beta], tumor necrosis factor-alpha [TNF-alpha] and growth factors insulin-like growth factor-1 [IGF-1] platelet-derived growth factor [PDGF]) have been implicat...

journal_title：American journal of respiratory and critical care medicine

authors： Jagirdar J,Begin R,Dufresne A,Goswami S,Lee TC,Rom WN

更新日期：1996-10-01 00:00:00