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Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome.

Abstract：

RATIONALE:Little is known about the long-term outcomes and costs of survivors of acute respiratory distress syndrome (ARDS). OBJECTIVES:To describe functional and quality of life outcomes, health care use, and costs of survivors of ARDS 2 yr after intensive care unit (ICU) discharge. METHODS:We recruited a cohort of ARDS survivors from four academic tertiary care ICUs in Toronto, Canada, and prospectively monitored them from ICU admission to 2 yr after ICU discharge. MEASUREMENTS:Clinical and functional outcomes, health care use, and direct medical costs. RESULTS:Eighty-five percent of patients with ARDS discharged from the ICU survived to 2 yr; overall 2-yr mortality was 49%. At 2 yr, survivors continued to have exercise limitation although 65% had returned to work. There was no statistically significant improvement in health-related quality of life as measured by Short-Form General Health Survey between 1 and 2 yr, although there was a trend toward better physical role at 2 yr (p = 0.0586). Apart from emotional role and mental health, all other domains remained below that of the normal population. From ICU admission to 2 yr after ICU discharge, the largest portion of health care costs for a survivor of ARDS was the initial hospital stay, with ICU costs accounting for 76% of these costs. After the initial hospital stay, health care costs were related to hospital readmissions and inpatient rehabilitation. CONCLUSIONS:Survivors of ARDS continued to have functional impairment and compromised health-related quality of life 2 yr after discharge from the ICU. Health care use and costs after the initial hospitalization were driven by hospital readmissions and inpatient rehabilitation.

journal_name

Am J Respir Crit Care Med

journal_title

American journal of respiratory and critical care medicine

authors

Cheung AM,Tansey CM,Tomlinson G,Diaz-Granados N,Matté A,Barr A,Mehta S,Mazer CD,Guest CB,Stewart TE,Al-Saidi F,Cooper AB,Cook D,Slutsky AS,Herridge MS

doi

10.1164/rccm.200505-693OC

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

538-44

issue

eissn

1073-449X

issn

1535-4970

pii

200505-693OC

journal_volume

174

pub_type

杂志文章

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Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome.