Use of the child health questionnaire in a sample of moderate and low-income inner-city children with asthma.

abstract：:This study was carried out to determine if the bronchoconstrictive effect of cigarette smoke (CS) is enhanced when airway hyperresponsiveness is induced by ovalbumin (Ova) sensitization, and if so, whether an increase in endogenously released tachykinins is involved. The bronchoconstrictive effects of an acute CS inha...

journal_title：American journal of respiratory and critical care medicine

authors： Wu ZX,Zhou D,Chen G,Lee LY

更新日期：2000-01-01 00:00:00

abstract：RATIONALE:The relationship between clinical phenotype of childhood primary ciliary dyskinesia (PCD) and ultrastructural defects and genotype is poorly defined. OBJECTIVES:To delineate clinical features of childhood PCD and their associations with ultrastructural defects and genotype. METHODS:A total of 118 participan...

journal_title：American journal of respiratory and critical care medicine

authors： Davis SD,Ferkol TW,Rosenfeld M,Lee HS,Dell SD,Sagel SD,Milla C,Zariwala MA,Pittman JE,Shapiro AJ,Carson JL,Krischer JP,Hazucha MJ,Cooper ML,Knowles MR,Leigh MW

更新日期：2015-02-01 00:00:00

abstract：:This prospective community-based study of infants born in inner London was undertaken to examine the association between premorbid airway function and subsequent wheezing in the first year of life and to explore the influence on this association of a family history of asthma and maternal smoking during pregnancy. Heal...

journal_title：American journal of respiratory and critical care medicine

authors： Dezateux C,Stocks J,Dundas I,Fletcher ME

更新日期：1999-02-01 00:00:00

abstract：RATIONALE:Although intensive care units (ICUs) were created for patients with life-threatening illnesses, the ICU environment generates a high risk of iatrogenic events. Identifying medical errors (MEs) that serve as indicators for iatrogenic risk is crucial for purposes of reporting and prevention. OBJECTIVES:We desc...

journal_title：American journal of respiratory and critical care medicine

authors： Garrouste-Orgeas M,Timsit JF,Vesin A,Schwebel C,Arnodo P,Lefrant JY,Souweine B,Tabah A,Charpentier J,Gontier O,Fieux F,Mourvillier B,Troché G,Reignier J,Dumay MF,Azoulay E,Reignier B,Carlet J,Soufir L,OUTCOMEREA Stu

更新日期：2010-01-15 00:00:00

abstract：:We hypothesized that variation in extubating brain injured patients would affect the incidence of nosocomial pneumonia, length of stay, and hospital charges. In a prospective cohort of consecutive, intubated brain-injured patients, we evaluated daily: intubation status, spontaneous ventilatory parameters, gas exchange...

journal_title：American journal of respiratory and critical care medicine

authors： Coplin WM,Pierson DJ,Cooley KD,Newell DW,Rubenfeld GD

更新日期：2000-05-01 00:00:00

abstract：:To examine whether diffuse pleural thickening (DPT) causes impairment of pulmonary function independent of other manifestations of asbestos-related disease, we studied individuals selected from 1,150 men with occupational asbestos exposure who had undergone pulmonary function testing and computed tomographic (CT) scan...

journal_title：American journal of respiratory and critical care medicine

authors： Kee ST,Gamsu G,Blanc P

更新日期：1996-09-01 00:00:00

abstract：RATIONALE:From the late 1970s to the early 1990s, studies found that mortality rates for pulmonary fibrosis were increasing. Recent data for mortality from pulmonary fibrosis are unavailable. OBJECTIVES:We sought to determine mortality rates for pulmonary fibrosis in the United States from 1992 through 2003. METHODS:...

journal_title：American journal of respiratory and critical care medicine

authors： Olson AL,Swigris JJ,Lezotte DC,Norris JM,Wilson CG,Brown KK

更新日期：2007-08-01 00:00:00

abstract：:Because inflammation stimulates the expression of inducible nitric oxide (NO) synthase (iNOS) with an associated increased local NO production, we hypothesized that patients with pneumonia would have increased excretion of NO into their airways. To test this hypothesis, NO was measured in the exhaled air and from the ...

journal_title：American journal of respiratory and critical care medicine

authors： Adrie C,Monchi M,Dinh-Xuan AT,Dall'Ava-Santucci J,Dhainaut JF,Pinsky MR

更新日期：2001-04-01 00:00:00

abstract：:The clinical significance of minimal acute rejection (grade A1) in lung transplant recipients is unknown. We prospectively analyzed 1,159 transbronchial lung biopsies in 184 patients. Two hundred seventy-nine biopsies in 128 participants confirmed A1 histology at a mean postoperative day of 229 +/- 340. Sixty four of ...

journal_title：American journal of respiratory and critical care medicine

authors： Hopkins PM,Aboyoun CL,Chhajed PN,Malouf MA,Plit ML,Rainer SP,Glanville AR

更新日期：2004-11-01 00:00:00

abstract：:In anaphylactic shock (AS), the relative effects of the autacoids including histamine, prostaglandins, and leukotrienes on causing cardiovascular collapse and the extent to which receptor blocking agents and pathway inhibitors may prevent this collapse are not clear. In a ragweed model of anaphylaxis, we examined whet...

journal_title：American journal of respiratory and critical care medicine

authors： Chrusch C,Sharma S,Unruh H,Bautista E,Duke K,Becker A,Kepron W,Mink SN

更新日期：1999-10-01 00:00:00

abstract：:A variety of substances including human meconium have been found to affect adversely the surface tension-lowering activity of pulmonary surfactants, and this effect may be important in the pathogenesis of a number of human diseases. To find whether inactivation of surfactant could be prevented or reduced by nonionic p...

journal_title：American journal of respiratory and critical care medicine

authors： William Taeusch H,Lu KW,Goerke J,Clements JA

更新日期：1999-05-01 00:00:00

abstract：:Ineffective lung repair in patients with unresolving acute respiratory distress syndrome (ARDS) is accompanied by progressive fibroproliferation, inability to improve lung injury score (LIS), progressive multiple organ dysfunction syndrome (MODS), and an unfavorable outcome. Our aim was to investigate the relationship...

journal_title：American journal of respiratory and critical care medicine

authors： Meduri GU,Tolley EA,Chinn A,Stentz F,Postlethwaite A

更新日期：1998-11-01 00:00:00

abstract：:Little is known about the structural response of the diaphragm to controlled mechanical ventilation. We examined effects of this intervention on muscle mass, myosin heavy chain isoforms, and contractile function in the rat diaphragm. Animals were mechanically ventilated for up to 4 days, and comparisons were made with...

journal_title：American journal of respiratory and critical care medicine

authors： Yang L,Luo J,Bourdon J,Lin MC,Gottfried SB,Petrof BJ

更新日期：2002-10-15 00:00:00

abstract：RATIONALE:Long-term intermittent hypoxia (LTIH) exposure in adult mice, modeling oxygenation patterns of moderate-severe obstructive sleep apnea, results in lasting hypersomnolence and is associated with nitration and oxidation injuries in many brain regions, including wake-active regions. OBJECTIVES:We sought to dete...

journal_title：American journal of respiratory and critical care medicine

authors： Zhan G,Fenik P,Pratico D,Veasey SC

更新日期：2005-06-15 00:00:00

abstract：:Loss of lung elastic recoil causing hyperinflation with increased TLC and decreased diffusing capacity and expiratory airflow are physiologic hallmarks of emphysema. We studied lung mechanics in 10 patients (seven men and three women) aged 69 +/- 9 yr (mean +/- SD) who had fixed, severe expiratory airflow limitation w...

journal_title：American journal of respiratory and critical care medicine

authors： Gelb AF,Zamel N,Hogg JC,Müller NL,Schein MJ

更新日期：1998-09-01 00:00:00

abstract：RATIONALE:Epidemiological studies in older individuals have found an association between the use of angiotensin-converting enzyme (ACE) inhibition (ACE-I) therapy and preserved locomotor muscle mass, strength, and walking speed. ACE-I therapy might therefore have a role in the context of pulmonary rehabilitation (PR). ...

journal_title：American journal of respiratory and critical care medicine

authors： Curtis KJ,Meyrick VM,Mehta B,Haji GS,Li K,Montgomery H,Man WD,Polkey MI,Hopkinson NS

更新日期：2016-12-01 00:00:00

abstract：:We enrolled nine allergic subjects in a double blind, placebo-controlled study to examine the effect of premedication with 0.6 mg of atropine on nasal antigen challenge. The challenge consisted of unilaterally stimulating the nasal septum with diluent followed by three increasing doses of antigen and recording respons...

journal_title：American journal of respiratory and critical care medicine

authors： Baroody FM,Ford S,Lichtenstein LM,Kagey-Sobotka A,Naclerio RM

更新日期：1994-06-01 00:00:00

abstract：:Asthma and chronic bronchitis are inflammatory diseases with extracellular matrix (ECM) remodeling and collagen deposition. Collagen homeostasis is controlled by metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). We evaluated MMP and TIMP balance in induced sputum of 10 control, 31 untreate...

journal_title：American journal of respiratory and critical care medicine

authors： Vignola AM,Riccobono L,Mirabella A,Profita M,Chanez P,Bellia V,Mautino G,D'accardi P,Bousquet J,Bonsignore G

更新日期：1998-12-01 00:00:00

abstract：:The demand for intensivists is increasing around the world, not only to meet the needs of a growing aging population, but also to fill positions in the intensive care unit now occupied by other specialists, since there is compelling evidence that the presence of critical care practitioners improves patient outcomes. N...

journal_title：American journal of respiratory and critical care medicine

authors： Estenssoro E,Valente Barbas CS,Briva A

更新日期：2013-01-15 00:00:00

abstract：:Pulmonary tuberculosis, one of the granulomatous diseases, has few serological markers for its activity. Recently, an increased serum level of vascular endothelial growth factor (VEGF) was detected in patients with Crohn's disease, also a granulomatous disease. We hypothesized that VEGF might be associated with the pa...

journal_title：American journal of respiratory and critical care medicine

authors： Matsuyama W,Hashiguchi T,Matsumuro K,Iwami F,Hirotsu Y,Kawabata M,Arimura K,Osame M

更新日期：2000-09-01 00:00:00

abstract：:We describe two reliable methods for high-throughput screening of proteinase inhibitor (PI) S and PI Z alpha(1)-antitrypsin (alpha(1)-AT) deficiency alleles from dried blood spot (DBS) specimens using the LightCycler fluorimetric analyzer. The method was used to study 72 patients with chronic obstructive pulmonary dis...

journal_title：American journal of respiratory and critical care medicine

authors： Rodriguez F,Jardí R,Costa X,Cotrina M,Galimany R,Vidal R,Miravitlles M

更新日期：2002-09-15 00:00:00

abstract：:The pathophysiology of impaired exercise tolerance in patients with cystic fibrosis (CF) is not completely understood. The objective of this study was to compare exercise ability (at clinical and cellular levels) and resting energy expenditure in female athletes with CF compared with matched control subjects. Sixteen ...

journal_title：American journal of respiratory and critical care medicine

authors： Selvadurai HC,Allen J,Sachinwalla T,Macauley J,Blimkie CJ,Van Asperen PP

更新日期：2003-12-15 00:00:00

abstract：RATIONALE:Cytokine receptors can be markers defining different T-cell subsets and considered as therapeutic targets. The association of IL-6 and IL-6 receptor α (IL-6Rα) with asthma was reported, suggesting their involvement in asthma. OBJECTIVES:To determine whether and how IL-6Rα defines a distinct effector memory (...

journal_title：American journal of respiratory and critical care medicine

authors： Lee N,You S,Shin MS,Lee WW,Kang KS,Kim SH,Kim WU,Homer RJ,Kang MJ,Montgomery RR,Dela Cruz CS,Shaw AC,Lee PJ,Chupp GL,Hwang D,Kang I

更新日期：2014-12-15 00:00:00

abstract：RATIONALE:The relative contribution of body proportion and social exposures to ethnic differences in lung function has not previously been reported in the United Kingdom. OBJECTIVES:To examine ethnic differences in lung function in relation to anthropometry and social and psychosocial factors in early adolescence. ME...

journal_title：American journal of respiratory and critical care medicine

authors： Whitrow MJ,Harding S

更新日期：2008-06-01 00:00:00

abstract：RATIONALE:Recent studies have suggested that both embryonic stem cells and adult bone marrow stem cells can participate in the regeneration and repair of diseased adult organs, including the lungs. However, the extent of airway epithelial remodeling with adult marrow stem cells is low, and there are no available in viv...

journal_title：American journal of respiratory and critical care medicine

authors： Sueblinvong V,Loi R,Eisenhauer PL,Bernstein IM,Suratt BT,Spees JL,Weiss DJ

更新日期：2008-04-01 00:00:00

abstract：:The respiratory-related evoked potential (RREP) is the electroencephalographic response to brief inspiratory occlusion. The P3 component of the response reflects the active cognitive processing of stimulus information. This study investigated the RREP in 16 subjects with asthma and 16 control subjects. In addition, au...

journal_title：American journal of respiratory and critical care medicine

authors： Webster KE,Colrain IM

更新日期：2002-07-01 00:00:00

abstract：:To gain insight into the source of exhaled nitric oxide (NO) in normal humans, we examined the effects of respiratory pattern on the concentration of NO in exhaled air while subjects were wearing a noseclip and then under endotracheal intubation, using a specially designed gas sampling system to separate exhaled air i...

journal_title：American journal of respiratory and critical care medicine

authors： Tsujino I,Miyamoto K,Nishimura M,Shinano H,Makita H,Saito S,Nakano T,Kawakami Y

更新日期：1996-11-01 00:00:00

abstract：:Rationale: Guidelines for vasopressor titration suggest a universal target-mean arterial pressure (MAP) >65 mm Hg. The implications for patients with premorbid low/high blood pressure are unknown.Objectives: To investigate the relationship between premorbid blood pressure and vasopressor duration for patients with sho...

journal_title：American journal of respiratory and critical care medicine

authors： Gershengorn HB,Stelfox HT,Niven DJ,Wunsch H

更新日期：2020-07-01 00:00:00

abstract：:Sensitive measures of lung function applicable to young subjects are needed to detect early cystic fibrosis (CF) lung disease. Forty children with CF aged 2 to 5 years and 37 age-matched healthy control subjects performed multiple-breath inert gas washout, plethysmography, and spirometry. Thirty children in each group...

journal_title：American journal of respiratory and critical care medicine

authors： Aurora P,Bush A,Gustafsson P,Oliver C,Wallis C,Price J,Stroobant J,Carr S,Stocks J,London Cystic Fibrosis Collaboration.

更新日期：2005-02-01 00:00:00

abstract：:Airway obstruction (AO) in exercise-induced asthma (EIA) is considered a postexercise phenomenon. However, many with EIA complain of respiratory distress during exercise. We evaluated AO in six asthmatic subjects during a short (SX = 6 min) and a long (LX = 20 min) exercise session. We measured peak expiratory flow (P...

journal_title：American journal of respiratory and critical care medicine

authors： Suman OE,Babcock MA,Pegelow DF,Jarjour NN,Reddan WG

更新日期：1995-07-01 00:00:00