Predictors of outcome and long-term survival in patients with pleural infection.

abstract：RATIONALE:The relative contribution of body proportion and social exposures to ethnic differences in lung function has not previously been reported in the United Kingdom. OBJECTIVES:To examine ethnic differences in lung function in relation to anthropometry and social and psychosocial factors in early adolescence. ME...

journal_title：American journal of respiratory and critical care medicine

authors： Whitrow MJ,Harding S

更新日期：2008-06-01 00:00:00

abstract：:The plasma level of fibrinogen is felt to be an independent risk factor for vascular events. Obstructive sleep apnea (OSA) has a high prevalence in patients with stroke and may also be an independent risk factor. The aim of our study was to determine the association between OSA and plasma levels of fibrinogen in patie...

journal_title：American journal of respiratory and critical care medicine

authors： Wessendorf TE,Thilmann AF,Wang YM,Schreiber A,Konietzko N,Teschler H

更新日期：2000-12-01 00:00:00

abstract：:Great emphasis is placed on educating asthmatics to use action plans to achieve better control of symptoms. The use of peak flow meters (PFM) has been recommended as an important part of self-management plans. We studied 92 (47 F) adult patients with asthma in a primary care setting to compare the effectiveness of act...

journal_title：American journal of respiratory and critical care medicine

authors： Turner MO,Taylor D,Bennett R,Fitzgerald JM

更新日期：1998-02-01 00:00:00

abstract：RATIONALE:Protein kinase C zeta (PKCζ) has been reported to act as a tumor suppressor. Deletion of PKCζ in experimental cancer models has been shown to increase tumor growth. However, the mechanisms of PKCζ down-regulation in cancerous cells have not been previously described. OBJECTIVES:To determine the molecular mec...

journal_title：American journal of respiratory and critical care medicine

authors： Queisser MA,Dada LA,Deiss-Yehiely N,Angulo M,Zhou G,Kouri FM,Knab LM,Liu J,Stegh AH,DeCamp MM,Budinger GR,Chandel NS,Ciechanover A,Iwai K,Sznajder JI

更新日期：2014-09-15 00:00:00

abstract：RATIONALE:Airway remodeling is an important feature of chronic asthma that causes irreversible airflow obstruction. Although asthma is considered to be a Th2 disease, the role of T-bet and GATA-3, the key transcription factors for differentiation toward Th1 and Th2 cells, in the pathogenesis of airway remodeling is poo...

journal_title：American journal of respiratory and critical care medicine

authors： Kiwamoto T,Ishii Y,Morishima Y,Yoh K,Maeda A,Ishizaki K,Iizuka T,Hegab AE,Matsuno Y,Homma S,Nomura A,Sakamoto T,Takahashi S,Sekizawa K

更新日期：2006-07-15 00:00:00

abstract：:The number and significance of airway eosinophils in stable COPD is controversial. Aims of this study were to evaluate airway inflammation in patients with stable COPD compared with other groups, and to examine the correlations between inflammatory markers and functional indices of airway obstruction. Cellular analysi...

journal_title：American journal of respiratory and critical care medicine

authors： Balzano G,Stefanelli F,Iorio C,De Felice A,Melillo EM,Martucci M,Melillo G

更新日期：1999-11-01 00:00:00

abstract：:Clinically, the spread of infectious agents between subjects undergoing spirometry is quite uncommon. There is almost no documentation in the medical literature on this subject. We studied the retrieval of nonpathogenic Escherichia coli after aerosolizing organisms into standard pulmonary function tubing of a type tha...

journal_title：American journal of respiratory and critical care medicine

authors： Hiebert T,Miles J,Okeson GC

更新日期：1999-02-01 00:00:00

abstract：:We described here an original device for laser Doppler (LD) flowmetry measurements of gastric mucosal perfusion, which was used here in healthy volunteers. A modified nasogastric tube containing the LD probe was inserted. Aspiration via a catheter, fixed in parallel to the probe, held the probe against the gastric wal...

journal_title：American journal of respiratory and critical care medicine

authors： Duranteau J,Sitbon P,Vicaut E,Descorps-Declère A,Vigue B,Samii K

更新日期：1996-12-01 00:00:00

abstract：:Impaired lung epithelial Na(+) channel (ENaC) activity at the time of birth results in respiratory distress. To investigate potential mechanisms, the ontogeny and cellular distribution of the alphaENaC subunit mRNA expression was studied in normal, immature, and abnormal (hypoplastic) human fetal lungs using nonradioi...

journal_title：American journal of respiratory and critical care medicine

authors： Smith DE,Otulakowski G,Yeger H,Post M,Cutz E,O'Brodovich HM

更新日期：2000-04-01 00:00:00

abstract：:Dysfunction of the muscles of ambulation contributes to exercise intolerance in chronic obstructive pulmonary disease (COPD). Men with COPD have high prevalence of low testosterone levels, which may contribute to muscle weakness. We determined effects of testosterone supplementation (100 mg of testosterone enanthate i...

journal_title：American journal of respiratory and critical care medicine

authors： Casaburi R,Bhasin S,Cosentino L,Porszasz J,Somfay A,Lewis MI,Fournier M,Storer TW

更新日期：2004-10-15 00:00:00

abstract：:Tracheal gas insufflation (TGI) has been recommended as an adjunct to mechanical ventilation in the presence of elevated Pa CO2. Based on our initial clinical experience with continuous flow TGI and pressure control ventilation (PCV), we were concerned about elevation in peak airway pressure as TGI was applied. In a l...

journal_title：American journal of respiratory and critical care medicine

authors： Imanaka H,Kacmarek RM,Ritz R,Hess D

更新日期：1996-03-01 00:00:00

abstract：:The blood beryllium lymphocyte proliferation test is used in medical surveillance to identify both beryllium sensitization and chronic beryllium disease. Approximately 50% of individuals with beryllium sensitization have chronic beryllium disease at the time of their initial clinical evaluation; however, the rate of p...

journal_title：American journal of respiratory and critical care medicine

authors： Newman LS,Mroz MM,Balkissoon R,Maier LA

更新日期：2005-01-01 00:00:00

abstract：:The expression of renin-angiotensin system components and the elevation of angiotensin-converting enzyme (ACE) in a number of fibrotic lung diseases suggests angiotensin II (AII) could play a role in the pathogenesis of pulmonary fibrosis. However, the effect of AII on lung fibroblasts has not previously been assessed...

journal_title：American journal of respiratory and critical care medicine

authors： Marshall RP,McAnulty RJ,Laurent GJ

更新日期：2000-06-01 00:00:00

abstract：RATIONALE:There is a need to develop novel noninvasive imaging biomarkers that help to evaluate antiinflammatory asthma treatments. OBJECTIVES:To investigate whether the extent of the segmental lung edema measured noninvasively using turbo-inversion recovery-magnitude magnetic resonance imaging (TIRM MRI) corresponds ...

journal_title：American journal of respiratory and critical care medicine

authors： Vogel-Claussen J,Renne J,Hinrichs J,Schönfeld C,Gutberlet M,Schaumann F,Winkler C,Faulenbach C,Krug N,Wacker FK,Hohlfeld JM

更新日期：2014-03-15 00:00:00

abstract：:The relationship between the severity of obstructive sleep apnea (OSA) (measured by sleep study) and daytime sleepiness is poor. Variation in the degree of arousal accompanying obstructive respiratory events might help explain this poor correlation. Polysomnographic records from patients with OSA were reviewed in orde...

journal_title：American journal of respiratory and critical care medicine

authors： Stradling JR,Pitson DJ,Bennett L,Barbour C,Davies RJ

更新日期：1999-01-01 00:00:00

abstract：RATIONALE:It is hypothesized that the affective dimension of dyspnea (unpleasantness, emotional response) is not strictly dependent on the intensity of dyspnea. OBJECTIVES:We tested the hypothesis that the ratio of immediate unpleasantness (A(1)) to sensory intensity (SI) varies depending on the type of dyspnea. METH...

journal_title：American journal of respiratory and critical care medicine

authors： Banzett RB,Pedersen SH,Schwartzstein RM,Lansing RW

更新日期：2008-06-15 00:00:00

abstract：:We investigated the source of intravascular fat in systemic organs (brain, heart, and kidney) after massive pulmonary fat embolism during cemented arthroplasty. We used a bilateral cemented arthroplasty (BCA) in anesthetized mongrel dogs that simulates a cemented total-hip replacement procedure. We hypothesized that d...

journal_title：American journal of respiratory and critical care medicine

authors： Byrick RJ,Mullen JB,Mazer CD,Guest CB

更新日期：1994-11-01 00:00:00

abstract：:We have investigated the influence of the cytokine tumor necrosis factor alpha (TNF alpha), an important mediator of sepsis, on in vitro hamster diaphragm contractility. Costal diaphragm strips were excised and mounted on an experimental apparatus consisting of a force transducer and servomotor. Preparations were rand...

journal_title：American journal of respiratory and critical care medicine

authors： Wilcox P,Milliken C,Bressler B

更新日期：1996-05-01 00:00:00

abstract：:Although there is abundant clinical evidence of asthmatic responses to indoor aeroallergens, the symptomatic impacts of other common indoor air pollutants from gas stoves, fireplaces, and environmental tobacco smoke have been less well characterized. These combustion sources produce a complex mixture of pollutants, ma...

journal_title：American journal of respiratory and critical care medicine

authors： Ostro BD,Lipsett MJ,Mann JK,Wiener MB,Selner J

更新日期：1994-06-01 00:00:00

abstract：:Asthmaexpert, an expert system (ES), was produced at the special request of several clinicians in order to better understand the medical decisions made clinical experts in managing an asthmatic patient. We describe and evaluate this knowledge base, focusing mainly on assessment of the severity of asthma. After compili...

journal_title：American journal of respiratory and critical care medicine

authors： Redier H,Daures JP,Michel C,Proudhon H,Vervloet D,Charpin D,Marsac J,Dusser D,Brambilla C,Wallaert B

更新日期：1995-02-01 00:00:00

abstract：:Exhaled nitric oxide (eNO) is elevated in patients with inflammatory pulmonary diseases and it has attracted increasing interest as a simple, noninvasive marker of airway inflammation. Little is known, however, about factors that might affect eNO in healthy subjects. We measured eNO in 157 healthy 7- to 13-yr-old chil...

journal_title：American journal of respiratory and critical care medicine

authors： Franklin PJ,Taplin R,Stick SM

更新日期：1999-01-01 00:00:00

abstract：:Cryptogenic fibrosing alveolitis has been reported to be associated with an increased risk of lung cancer. However, it has recently become apparent that cigarette smoking may be a risk factor for cryptogenic fibrosing alveolitis as well as for lung cancer, and so may confound the association between these conditions. ...

journal_title：American journal of respiratory and critical care medicine

authors： Hubbard R,Venn A,Lewis S,Britton J

更新日期：2000-01-01 00:00:00

abstract：:Although airway inflammation is recognized as a key feature of asthma, the characteristics of airway inflammation in children with acute severe asthma are not well defined. The aim of this study was to describe the characteristics of airway inflammation in children with an acute exacerbation of asthma using sputum cel...

journal_title：American journal of respiratory and critical care medicine

authors： Norzila MZ,Fakes K,Henry RL,Simpson J,Gibson PG

更新日期：2000-03-01 00:00:00

abstract：:Airway obstruction (AO) in exercise-induced asthma (EIA) is considered a postexercise phenomenon. However, many with EIA complain of respiratory distress during exercise. We evaluated AO in six asthmatic subjects during a short (SX = 6 min) and a long (LX = 20 min) exercise session. We measured peak expiratory flow (P...

journal_title：American journal of respiratory and critical care medicine

authors： Suman OE,Babcock MA,Pegelow DF,Jarjour NN,Reddan WG

更新日期：1995-07-01 00:00:00

abstract：:We examined the efficacy and the acceptance of an oral device (SnorEx) causing a forward displacement of the tongue for the treatment of sleep-disordered breathing (SDB). Twenty-three consecutive subjects with SDB were investigated. Noncompliance (NC) of use of the oral appliance was observed in 74% (17 of 23) of the ...

journal_title：American journal of respiratory and critical care medicine

authors： Schönhofer B,Stoohs RA,Rager H,Wenzel M,Wenzel G,Köhler D

更新日期：1997-02-01 00:00:00

abstract：:A study was done to compare the efficacy and safety of the coprescription of salmeterol 50 microgram twice daily or 100 microgram twice daily with beclomethasone dipropionate (BDP) 500 micrograms twice daily (SALM 50 and SALM 100) with BDP 1,000 microgram twice daily (BDP 1,000) in patients with asthma not controlled ...

journal_title：American journal of respiratory and critical care medicine

authors： Woolcock A,Lundback B,Ringdal N,Jacques LA

更新日期：1996-05-01 00:00:00

abstract：:There have been four types of drug treatment of asthma that have been used over the past 100 years. Belladonna alkaloids, derived from the thorn-apple plant were used in 1905, and chemically synthesized entities in this class are still in use today. Western medicine began to use adrenergic stimulants approximately 100...

journal_title：American journal of respiratory and critical care medicine

authors： Chu EK,Drazen JM

更新日期：2005-06-01 00:00:00

abstract：:In asthma, the acute increment of airway responsiveness caused by exposure to allergen is associated with influx of eosinophils into the airways. The relationship between chronic airway hyperresponsiveness and airway inflammation is unclear, as they do not change consistently following long-term anti-inflammatory trea...

journal_title：American journal of respiratory and critical care medicine

authors： Crimi E,Spanevello A,Neri M,Ind PW,Rossi GA,Brusasco V

更新日期：1998-01-01 00:00:00

abstract：:Observation of bronchus-associated lymphoid tissue (BALT) in whole lung specimens from healthy nonsmoking adults has questioned the hypothesis that BALT is not constitutively present in healthy adult human lungs. In our study, we investigated endobronchial biopsies of the second- and third-generation carinae from 44 c...

journal_title：American journal of respiratory and critical care medicine

authors： Sue-Chu M,Karjalainen EM,Altraja A,Laitinen A,Laitinen LA,Naess AB,Larsson L,Bjermer L

更新日期：1998-08-01 00:00:00

abstract：:We determined if pulmonary peptidoleukotrienes contribute to the pathogenesis of chronic lung disease of extreme prematurity (CLD) by measuring urinary leukotriene E4 (uLTE4). Study patients had a birth weight < 1000 g and were about 28 d old when they were classified as normal control subjects (n = 8) or as having CL...

journal_title：American journal of respiratory and critical care medicine

authors： Davidson D,Drafta D,Wilkens BA

更新日期：1995-03-01 00:00:00