Abstract：
:Immunohistochemistry of normal eccrine sweat glands was performed on paraffin sections of human skin. Immunoreactivity (ir) for neuron specific enolase, S100 protein (S100), regulatory peptides, nitric oxide synthase type I (NOS-I) and choline-acetyltransferase (ChAT) was found in small nerve bundles close to sweat glands. In the glands, secretory cells were labelled with anticytokeratin antibody. Using antibodies to S100, calcitonin gene-related peptide (CGRP) and substance P (SP) a specific distribution pattern was found in secretory cells. Granulated (dark) and parietal (clear) cells were immunopositive for CGRP, and S100 and SP, respectively. Immunoreactivity was diffuse in the cytoplasm for CGRP and S100, and peripheral for SP. Myoepithelial cells were not labelled. Electron microscopy revealed electron dense granules, probably containing peptide, in granulated cells. Using antibodies to NOS-I and ChAT, ir was exclusively found in myoepithelial cells. Immunoreactivity for the atrial natriuretic peptide was absent in sweat glands. These results provide evidence for the presence of both regulatory peptides involved in vasodilation and key enzymes for the synthesis of nitric oxide and acetylcholine in the secretory coil of human sweat glands. It is suggested that human sweat glands are capable of some intrinsic regulation in addition to that carried out by their nerve supply.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Zancanaro C,Merigo F,Crescimanno C,Orlandini S,Osculati Adoi
10.1046/j.1469-7580.1999.19430433.xkeywords:
subject
Has Abstractpub_date
1999-04-01 00:00:00pages
433-44eissn
0021-8782issn
1469-7580journal_volume
194 ( Pt 3)pub_type
杂志文章abstract：:Horns are permanent structures projecting from the head of bovids, consisting of a bony horncore covered with a layer of skin and then a sheath of keratinous material showing variability of growth intensity based on nutrition. From the point of view of the horn's mechanical properties, the keratin sheath has been wide...
journal_title：Journal of anatomy
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abstract：:Following the discovery that the proto-oncogene protein kinase B (PKB) functions as a downstream element in signalling from phosphoinositide 3'-kinase (PI3-kinase) (Burgering & Coffer, 1995), PKB has been shown to mediate a diverse array of PI3-kinase dependent cellular responses. Most recently PKB-dependent phosphory...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
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abstract：:Developing Xenopus embryos treated during gastrulation with 22 micrograms/l of salmar calcitonin in the ambient water develop into larvae exhibiting a decrease in interocular distance. In view of the hypocalcaemic properties of calcitonin and the importance of calcium ions in cell aggregation, this phenomenon has been...
journal_title：Journal of anatomy
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章,评审
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
pub_type： 杂志文章,评审
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journal_title：Journal of anatomy
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doi：
更新日期：1989-12-01 00:00:00
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journal_title：Journal of anatomy
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doi：
更新日期：1991-04-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章,评审
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journal_title：Journal of anatomy
pub_type： 杂志文章
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更新日期：2011-09-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00503.x
更新日期：2006-01-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00743.x
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13228
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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doi：
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
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journal_title：Journal of anatomy
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更新日期：1996-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Lateral nasal glands of 12-15 weeks old pups are immature. Gland acini of pups and mature dogs contain numerous electron-lucent vacuoles with basophilic, electron-dense cores. The vacuoles contain both acid and neutral glycoproteins, sialated glycoproteins being the dominant acidic moiety. Lateral and basal cytoplasmi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00197.x
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