Abstract:
:The bioavailability of polystyrene particles (1 microns) labelled with FITC (3M Company, Düsseldorf) was tested in rats after enteral administration. Since macromolecules and particles are preferentially transported in the lymph, the number of particles was counted in the lymph of the thoracic duct over a 6 h period. Uptake in young rats (6-8 wk) was compared with that in 5 and 9 mo animals. Young animals absorbed only 87 particles whereas a marked increase in the uptake of particles was observed in 5 mo animals (up to 775) but there was a decrease to 518 particles in older animals (9 mo). This number of particles is the total number of the entire output of the thoracic duct lymph over a 6 h period. In individual animals this number showed a considerable fluctuation over time. The volume of the collected lymph fluid was relatively constant (3.5 +/- 0.5 ml) in all animals. The bioavailability of the particles in the lymph was also influenced by the applied dose of particles. After intraduodenal administration of 3.7 x 10(5) particles only 18 particles could be found in the lymph. Increasing the dose to 3.7 x 10(7) particles raised the number of particles in the lymph to 116. The highest dose of 3.7 x 10(9) was correlated with the greatest absorption, 775 particles being found in the lymph. The uptake of particles from the gut thus depends on different factors including the age of the animal and the number of applied particles.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Seifert J,Haraszti B,Sass Wsubject
Has Abstractpub_date
1996-12-01 00:00:00pages
483-6eissn
0021-8782issn
1469-7580journal_volume
189 ( Pt 3)pub_type
杂志文章abstract::The koala has an inguinoaxillary lymph trunk on either side of the ventral midline, and this carries efferent lymph from the superficial inguinal lymph node directly to the deep axillary lymph node. The superficial lymph nodes are large and soft compared with those of the domestic species, and each lymph centre usuall...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00
abstract::Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assesse...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.01015.x
更新日期:2009-01-01 00:00:00
abstract::Due to conflicting data from previous studies a new methodological approach to evaluate heel pad stiffness and soft tissue deformation has been developed. The purpose of this study was to compare heel pad (HP) stiffness in both limbs between males and females during a dynamic unloading and loading activity. Ten males ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13207
更新日期:2020-09-01 00:00:00
abstract::The morphological transition from the simple epidermis that contacts the amniotic fluid of embryonic crocodilians to the adult epidermis required in a terrestrial environment has never been described. We used light and electron microscopy to study the development, differentiation and keratinisation of the epidermis of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19830265.x
更新日期:2001-03-01 00:00:00
abstract::The structure of the sinuatrial nodal artery has been investigated in young and old rats. The nodal artery is derived from the internal thoracic artery, runs centrally though the node and supplies it by several branches. An extensive cuff of nodal cells is seen within the adventitia of the artery and its branches adja...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::The regeneration of adrenocortical autotransplants in the rat spleen has been investigated by light and electron microscopy. Up to the seventh day after implantation, adrenal grafts showed large areas of necrosis and contained many degenerating (apoptotic) adrenocortical cells, some mesenchyme-like poorly differentiat...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::A stereological analysis of the mitochondrial compartment of the rabbit parotid gland has been carried out before and after isoprenaline-induced degranulation. Normally, mitochondria constitute about 5% of acinar cell volume, 6% of intercalcate duct cell volume and 16% of striated duct cell volume. The ratio of inner ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::Although the development of the avian skeleton has attracted considerable attention, most of the studies have been concentrated on the embryonic period, while studies on the postnatal period are rare. We studied the postnatal development of the skeleton in two phylogenetically distant birds, an altricial passerine Acr...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13303
更新日期:2021-02-01 00:00:00
abstract::A total histological grade does not necessarily distinguish between different manifestations of cartilage damage or degeneration. An accurate and reliable histological assessment method is required to separate normal and pathological tissue within a joint during treatment of degenerative joint conditions and to sub-cl...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01513.x
更新日期:2012-07-01 00:00:00
abstract::Contracture of collagen fibres in the gubernaculum has been suggested as a mechanism responsible for fetal descent of the testis. We measured the collagen content of the gubernaculum, fetal thigh muscle and umbilical cord tissue by assaying its hydroxyproline and protein content in 194 male pig fetuses between 60 and ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::The angularis oris gland, an avian salivary gland that lies beneath the zygomatic arch, was studied in the house sparrow by means of light and electron microscopy. The gland consists of lobules composed of epithelial tubules and folds on a delicate connective tissue framework. The lobules are drained by large channels...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract::Myocardial hyperplasia is generally considered to occur only during fetal development. However, recent evidence suggests that this type of response may also be triggered by cardiac overload after birth. In congenital heart disease, loading conditions are frequently abnormal, thereby affecting ventricular function. We ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00853.x
更新日期:2008-03-01 00:00:00
abstract::The ultrastructure of the basal lamina of histologically normal human breast tissue was determined in 19 women undergoing operations for removal of a fibroadenoma or reduction mammoplasty. The day of the menstrual cycle was determined by hormone assay and direct questioning. Previously documented ultrastructural appea...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::The fine structure of the intercellular junctions of the hen parathyroid gland was studied using freeze-fracture replicas and thin sections. In the conventional thin sections, desmosomes, intermediate junctions (maculae adherentes) and gap junctions were observed, and in the lanthanum-fixed sections, tight junctions (...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::The fossil record supports the conclusions derived from the study of extant species that the Primates evolved a unique suite of characters in the articulations of the foot. The tarsal bones of African Miocene apes show specializations characteristic of hominoid evolution and provide reasonable precursors for the morph...
journal_title:Journal of anatomy
pub_type: 历史文章,杂志文章
doi:
更新日期:1980-09-01 00:00:00
abstract::Genetic mutation leads to anatomical variation only indirectly because many proteins involved in generating anatomical structures in embryos operate cooperatively within molecular networks. These include gene-regulatory or control networks (CNs) for timing, signaling and patterning together with the process networks (...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12205
更新日期:2014-08-01 00:00:00
abstract::The differentiation of granulated metrial gland (GMG) cells has been investigated during deciduomata formation in radiation-induced chimeric mice reconstituted with rat or mouse bone marrow. The extent of the decidual reaction was apparently normal in regions of the uterine horns shielded from the irradiation but was ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract::Taurodontism (i.e. enlarged pulp chamber with concomitant apical displacement of the root bi/trifurcation) is considered a dental anomaly with relatively low incidence in contemporary societies, but it represents a typical trait frequently found in Neandertal teeth. Four hypotheses can be envisioned to explain the hig...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12260
更新日期:2015-02-01 00:00:00
abstract::The blood supply to the cranial venae cavae on both sides and to the heart was studied macroscopically in 40 adult laboratory shrews (Suncus murinus) of both sexes injected either with Neoprene latex into the abdominal aorta (25 animals) or with Mercox into the left ventricle (15 animals). The 1st branch of the left s...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Proximal femoral morphology and associated musculature are of special relevance to the understanding of hominoid locomotor systems. Knowledge of bone-muscle correspondence in extant hominoids forms an important comparative basis for inferring structure-function relationships in fossil hominids. However, there is still...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12270
更新日期:2015-03-01 00:00:00
abstract::We studied the cerebellar connections to the reticular nucleus thalamus (RNT) by means of retrograde axonal transport of horseradish peroxidase (HRP) in the rat. Specific HRP pressure injections to the rostral RNT (1.6-1.8 mm caudal to bregma) resulted in retrograde labelling of neurones in the cerebellar nuclei. The ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2002.00119.x
更新日期:2002-12-01 00:00:00
abstract::In zoology it is well known that birds are characterized by the presence of feathers, and mammals by hairs. Another common point of view is that avian scales are directly related to reptilian scales. As a skin embryologist, I have been fascinated by the problem of regionalization of skin appendages in amniotes through...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2008.01041.x
更新日期:2009-04-01 00:00:00
abstract::Complex I is one of the respiratory chain enzymes related to NADH dehydrogenase and is an encoded gene product derived from both nuclear and mitochondrial genomes. Transcription levels of ND1 (mitochondrial) and 51 kDa (nuclear) subunits of complex I in the postnatal development of the intrinsic muscle in rat tongues ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00152.x
更新日期:2003-02-01 00:00:00
abstract::Growth affects the performance of structure, so the pattern of growth must influence the role of a structure and an organism. Because animal performance is linked to morphological specialization, ontogenetic change in size may influence an organism's biological role. High bite force generation is presumably selected f...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12342
更新日期:2015-09-01 00:00:00
abstract::The pituitary of roach, Rutilus rutilus (L.), is pear-shaped and situated in the sella turcica. It is characterised by a large pars nervosa, which penetrates deep into the other regions, splitting the proximal pars distalis. Spatial localisation of nerve fibre types and glandular cell types occurs. Using a variety of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::The histogenesis of the isocortical segment of the lateral telencephalic wall at the coronal level of the interventricular foramen was studied in mice between the ages of E10 and the adult. The proliferative activity of the periventricular germinal layers was correlated with changes in cell distributions in the interm...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-05-01 00:00:00
abstract::Guinea-pig ovarian follicles were studied by light and electron microscopy. All freshly ruptured follicles showed small blood vessels within the stratum granulosum as well as amongst the cells of the theca interna. The evidence suggests that the marked increase in the size of the preovulatory follicle stretches the ba...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::By relating an animal's morphology to its functional role and the behaviours performed, we can further develop our understanding of the selective factors and constraints acting on the adaptations of great apes. Comparison of muscle architecture between different ape species, however, is difficult because only small sa...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2011.01383.x
更新日期:2011-08-01 00:00:00
abstract::Elastic fibres, which are intimately associated with collagen, a major component of the urethra, have been assumed to contribute to the resting urethral closure pressure. The Miller stain for elastin was used to demonstrate elastic fibres in cryostat sections of guinea pig bladder base, vesicourethral junction (VUJ) a...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19530447.x
更新日期:1999-10-01 00:00:00
abstract::The ACTH cells form a layer 1-8 cells thick, dorsal to the prolactin cells in the rostral pars distalis. They react only mildly with a variety of stains including PAS-lead haematoxylin. Their nuclear diameters vary seasonally in a manner that closely parallels that of the prolactin cells. The relative volumes of the A...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00