Abstract:
OBJECTIVE:To measure autoantibodies that recognize oxidatively modified proteins in the sera of women with surgically proven endometriosis. DESIGN:Prospective study. SETTING:Tertiary care academic medical center. PATIENT(S):Women undergoing surgery for endometriosis or tubal ligation. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Serum and peritoneal fluid autoantibody titers to malondialdehyde-modified low-density lipoprotein, oxidized low-density lipoprotein, and lipid peroxide-modified rabbit serum albumin determined by ELISA. Correlation of autoantibody titers with revised American Fertility Society staging classification, symptoms, and morphologic type of endometriosis. RESULT(S):Mean (+/-SEM) serum autoantibody titers (in optical density units) to the three antigens were as follows: [1] lipid peroxide-modified rabbit serum albumin, 0.49 +/- 0.12 units in the patients with endometriosis and 0.2 +/- 0.02 units in the controls; [2] oxidized low-density lipoprotein, 0.22 +/- 0.005 units in the patients with endometriosis and 0.18 +/- 0.006 units in the controls; and [3] malondialdehyde-modified low-density lipoprotein, 0.21 +/- 0.005 units in the patients with endometriosis and 0.16 +/- 0.003 units in the controls. There was no correlation between autoantibody titers and revised American Fertility Society stage, symptoms, or morphologic type of endometriosis. Peritoneal fluid did not contain autoantibodies to any of the three antigens. CONCLUSION(S):Autoantibodies to markers of oxidative stress were significantly increased in women with endometriosis. These findings strongly support our data demonstrating that women with endometriosis have enhanced oxidative stress.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Shanti A,Santanam N,Morales AJ,Parthasarathy S,Murphy AAdoi
10.1016/s0015-0282(99)00145-4keywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
1115-8issue
6eissn
0015-0282issn
1556-5653pii
S0015-0282(99)00145-4journal_volume
71pub_type
杂志文章abstract::22 physician-providers who serve natural family planning (NFP) programs, mostly in the private sector, gathered to formulate a standard terminology for the field. The Billings and sympto-thermal methods are the 2 methods taught by this group. The sypto-thermal method helps a woman predict ovulation by detecting chan...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)46409-5
更新日期:1982-07-01 00:00:00
abstract::The transcervical division of uterine septa is usually described as a simple procedure associated with minimal morbidity. Two cases are presented describing late hemorrhage after this procedure. Approaches to avoiding this complication as well as management principles are described. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54984-x
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:To review recent advances in understanding the role of leptin in the physiology and pathophysiology of reproduction, with a focus on relevant clinical situations. DESIGN:A MEDLINE computer search was performed to identify relevant articles. RESULT(S):Leptin, an adipocyte hormone important in regulating ener...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(01)03010-2
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:To evaluate tubal morphology, trophoblast proliferation, and inflammatory reaction in response to methotrexate (MTX) treatment of ectopic pregnancy (EP). DESIGN:Nonrandomized controlled study. SETTING:Academic hospital. PATIENTS:Archival specimens from 10 EP unsuccessfully treated with MTX and 10 cases pri...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:To prove that low-dose hCG alone can be clinically used to replace FSH-containing gonadotropins to complete controlled ovarian hyperstimulation (COH). DESIGN:Controlled, prospective, randomized study. SETTING:Academic center. PATIENT(S):Infertile patients who are candidates for assisted reproduction. INTE...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2005.02.036
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:To elucidate the role of vitamin D in reproduction by examining the relationship between recipient vitamin D levels and pregnancy rates in donor-recipient IVF cycles. DESIGN:Retrospective cohort study. SETTING:Academic tertiary care center. PATIENT(S):Ninety-nine recipients of egg donation at University of...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.10.008
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To demonstrate a new approach for performing an ovarian cystectomy via transvaginal natural orifice transluminal endoscopic surgery (vNOTES) as an alternative for a laparoscopic ovarian cystectomy. DESIGN:Stepwise explanation of the technique using original video footage. SETTING:Hospital. PATIENT(S):Fourt...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2017.10.037
更新日期:2018-02-01 00:00:00
abstract::To date, ovum donation (OD) has involved luteinizing hormone (LH) synchronization between recipient and donor for normally cycling women, and a complex steroid replacement regimen given on a sequential and incremental basis for women with primary or secondary ovarian failure. The authors designed a simple hormonal reg...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59354-6
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVE:To study concordance rates of cryptorchidism (undescended testis) in pairs of boys with varying family structure, to evaluate the risk contribution from the intrauterine environment and genetic factors. DESIGN:Population based study of 1,024,500 Danish boys born from January 1, 1973 to December 31, 2004. Cla...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.09.041
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of the 2004 Italian regulations (insemination of journal_title:Fertility and sterility pub_type: 杂志文章 doi:10.1016/j.fertnstert.2007.04.051 更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To investigate the functional and sexual outcome of sigmoid vaginoplasty in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Fifty-nine consecutive patients with MRKH syndrome. INTERVENTION(S):Forty-eight patients underwent sig...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.12.015
更新日期:2012-03-01 00:00:00
abstract::Comparative studies have been carried out on the behavior of human and bovine spermatozoa toward homologous cervical mucus in vitro. In both cases the degree of sperm penetration and the pattern of sperm motility were influenced in a characteristic fashion by prior manipulation of the mucus: the most rapid and extensi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::The antiprogesterone compound RU 486 (17 beta-hydroxy-11 beta-[4-dimethylaminophenyl]-17 alpha-[ 1-propynyl]estra-4,9-dien-3-one; Roussel-Uclaf, Paris, France) was used to induce menstruation in a randomized controlled trial. Castrated adult female cynomolgus monkeys (n = 17) received sequential subcutaneous Silastic ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47246-8
更新日期:1983-08-01 00:00:00
abstract::One hundred and twenty rats were divided into six groups and laparotomized. In three of the groups the cecum was left intact. In one of these groups the cecum was only lifted up through the abdominal incision and then replaced in the abdominal cavity. In another group the intact cecum was bathed with a certain amount ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43584-3
更新日期:1978-10-01 00:00:00
abstract:OBJECTIVE:To study social and demographic differentiation of assisted reproduction technology (ART) use at the population level in the United States. DESIGN:Population-based study. SETTING:Not applicable. PATIENT(S):Women 15-49 years old in the American Community Survey and National Vital Statistics Birth Certificat...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2019.07.1323
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To improve posttransplantation survival of frozen-thawed human ovarian tissue in immunodeficient mice. DESIGN:Histologic study of transplanted human ovaries after treating the host and graft. SETTING:Infertility unit, university-affiliated tertiary medical center. PATIENT(S):Ovarian tissue from six girls/w...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.07.1082
更新日期:2011-03-15 00:00:00
abstract::Because spermatocyte meiotic error results in embryonic sex chromosomal aneuploidy, it is speculated that teratospermia correlates with increased embryonic sex chromosomal abnormalities. Our findings contradict this theory, suggesting that morphology does not correlate with sex chromosomal genotype. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.07.1006
更新日期:2010-02-01 00:00:00
abstract::The Ericsson albumin filtration technique was used to collect a fraction rich in Y sperm for selective insemination in couples desiring a male infant. Of 35 conceptions in which sex was known at delivery or spontaneous abortion, there were 28 males (80%). Twelve pregnancies were achieved after separation of sperm in a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract::We found the prevalence of ovarian cancer in infertile women less than 40 years at the time of planned microsurgery for infertility to be 1 in 95. This may represent a greater prevalence of ovarian cancer than that of all women less than 40 years. Importantly, laparoscopy did not find the ovarian cancer in these women...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract::This retrospective study examined the association of endometrial pattern and pregnancy after a day 5 ET. The pregnancy rate of women with a triple-line ultrasound endometrial pattern on the day of hCG administration was significantly higher than the pregnancy rate of women with the other ultrasound patterns. This obse...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.05.102
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To examine the underlying factors leading to infertility in a male patient from whom phospholipase C zeta H398P (PLCζ(H398P), histidine > proline) and PLCζ(H233L) (histidine > leucine) mutations were previously identified. DESIGN:Laboratory-based study. SETTING:University laboratory. PATIENT(S):An infertil...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.05.002
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcome of repeated electroejaculation for obtaining semen from adolescents and young men before initiation of anticancer therapies. DESIGN:Retrospective clinical study. SETTING:Bikur Cholim Hospital, Jerusalem, Israel. PATIENT(S):Six young male patients (average age, 18+/-3 years) with dia...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)01680-6
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:To compare final embryo disposition between patients and donor oocyte recipients. DESIGN:Retrospective study. SETTING:Private infertility practice. PATIENT(S):Patients undergoing IVF with embryo cryopreservation. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Final cryopreserved embryo disposition. RESUL...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.08.002
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To determine the effects of prior gravidity on hormonal parameters, medication regimen, oocyte parameters, fertilization, and clinical pregnancy rates (PRs) in donor and own oocyte cycles. DESIGN:A retrospective study of 64 first-attempt ovum donor cycles and 102 first-attempt IVF and ZIFT cycles using own o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58157-6
更新日期:1996-03-01 00:00:00
abstract::When dispersed spermatogenic cells obtained by enzymatic digestion from prepuberal mice, adult male mice, nonazoospermic men and normospermic men were observed live using Normarski optics, it was found that, respectively, 47.4%, 1.4%, 5.1%, and 2.4% of them protruded active pseudopodia. These cells were 8 to 10 mum in...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.06.055
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To determine if pentoxifylline has an in vitro effect on human sperm motility in subjects with normal semen analysis. DESIGN:Prospective, longitudinal study of the effect of pentoxifylline on normospermic semen samples using computerized analysis. SETTING:The Assisted Conception Unit, Royal Maternity Hospit...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)55708-2
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:To establish an intracytoplasmic sperm injection treatment program for couples with male infertility and to determine those factors important for success. DESIGN:A retrospective analysis of 171 consecutive cycles of intracytoplasmic sperm injection concerning 145 infertile couples. SETTING:Infertility clini...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)57489-5
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the occurrence of mutations of 5alpha-reductase type 2 gene in patients with cryptorchidism or idiopathic azoospermia. DESIGN:Controlled clinical study. SETTING:Yamagata University Hospital, Yamagata and Tokyo Electric Power Company Hospital, Tokyo, Japan. PATIENT(S):Patients with isolated cryp...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(02)03220-x
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:To evaluate novel clinical markers of endometriosis including the neurotrophins brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and neurotrophin 4/5 (NT4/5) and compare them to others previously reported in the literature including cancer antigen 125 (CA-125) and C-reactive protein (CRP)....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.09.003
更新日期:2016-01-01 00:00:00
abstract::Three groups of dogs underwent testicular ischemia for a 3-hour period. Group I (10 animals) was not subsequently perfused. Group II (10 animals) underwent subsequent perfusion by a new in vivo reversible method via the internal spermatic artery with heparinized saline. Group III (5 animals) underwent perfusion with S...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42924-9
更新日期:1977-11-01 00:00:00