Abstract：
OBJECTIVE:To investigate the functional and sexual outcome of sigmoid vaginoplasty in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Fifty-nine consecutive patients with MRKH syndrome. INTERVENTION(S):Forty-eight patients underwent sigmoid vaginoplasty, and 11 were treated using the Frank method of dilatation. MAIN OUTCOME MEASURE(S):Functional results and sexuality were evaluated with the use of two standardized questionnaires: the Female Sexual Function Index (FSFI) and the revised Female Sexual Distress Scale (FSDS-R). Questions were added to analyze depression, body image perception, and desire of motherhood. RESULT(S):Out of the 68% of patients who answered the questionnaire, 73% had regular sexual intercourse. The mean total FSFI score was 28 ± 3.1 in the operated group and 30 ± 5.3 in the group treated with the Frank method. Their mean FSDS-R scores were 21 ± 12.1 and 18 ± 13.8, respectively. CONCLUSION(S):Sigmoid vaginoplasty is an effective technique providing a nearly normal sexual function to patients with vaginal aplasia. Despite this, psychologic distress related to sexuality persists in most patients, demonstrating the need for a multidisciplinary support.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Carrard C,Chevret-Measson M,Lunel A,Raudrant Ddoi
10.1016/j.fertnstert.2011.12.015subject
Has Abstractpub_date
2012-03-01 00:00:00pages
691-6issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(11)02867-6journal_volume
97pub_type
杂志文章abstract：OBJECTIVE:To present a case of Marfan syndrome and concurrent congenital obstructive azoospermia. DESIGN:Case report. SETTING:Tertiary-care academic hospital. PATIENT(S):A man with Marfan syndrome and obstructive azoospermia. INTERVENTION(S):The patient was evaluated for azoospermia that was proved to be due to con...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)02868-0
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVE:To describe the use of a Malecot catheter as a stent after radical trachelectomy (RT). DESIGN:Case report. SETTING:Assisted conception unit at a teaching hospital in the United Kingdom. PATIENT(S):A 36-year-old woman undergoing IVF after her cervix had been excised for cervical carcinoma. Previous attempts...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.081
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the mRNA levels of connexins in different sizes of luteinized follicles. DESIGN:Semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to determine the connexin mRNA levels in the granulosa cells of 91 luteinized follicles. SETTING:Academic tertiary care medical center and res...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.05.015
更新日期：2003-12-01 00:00:00
abstract：OBJECTIVE:To determine whether the presence of soluble human leukocyte antigen G (sHLA-G) affects implantation and pregnancy outcomes in vitro. DESIGN:A multicenter retrospective study. SETTING:Six certified in vitro fertilization (IVF) units. PATIENT(S):Embryos obtained from 2,040 patients from six different IVF cl...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2013.07.1977
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:To assess whether supplementation with hCG throughout the secretory phase of hormonally modulated cycles of frozen-thawed embryos might positively affect the outcome of such cycles. DESIGN:Prospective, randomized controlled trial. SETTING:University teaching hospital. PATIENT(S):Patients undergoing frozen-...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2009.02.027
更新日期：2010-02-01 00:00:00
abstract：:We found that there was no significant difference in endometrial responses to vaginal or IM P. But the response was suboptimal in cycles treated with dydrogesterone, suggesting that dydrogesterone treatment is not the preferred progestin for use in artificial cycles. ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)56840-x
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of progestogen supplementation in improving clinical pregnancy rates in women undergoing fresh IVF cycles and to compare different routes, start times, durations, and estrogen coadministration regimen. DESIGN:Comprehensive systematic review and meta-analysis. SETTING:University...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析
doi：10.1016/j.fertnstert.2019.04.021
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To clarify the role and mechanism of CCL2 in regulating the biological functions of endometrial stromal cells (ESCs). DESIGN:The CCL2 effect on the viability, proliferation, and invasion in the eutopic ESCs from endometriosis. SETTING:Research laboratories. PATIENT(S):Patients with endometriosis aged 23-47...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.12.049
更新日期：2012-04-01 00:00:00
abstract：:Some see an "alarming inconsistency" in candidate-screening practices of assisted reproductive technology (ART) programs and call for common guidelines. However, reasonable people can disagree about who should be prevented from having children and why. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.05.028
更新日期：2005-11-01 00:00:00
abstract：:Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiolog...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.01.059
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To investigate the expression and localization of interleukin-8 (IL-8) and monocyte chemotactic protein 1 (MCP-1) in women with and without endometriosis. DESIGN:Comparative immunohistochemical study. SETTING:Academic medical center. PATIENT(S):Ectopic (n = 24) and homologous eutopic endometrium (n = 24) f...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.12.067
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of coital lubricants and oils on sperm motility. DESIGN:Comparative prospective in vitro study. SETTING:University Andrology laboratory. PATIENT(S):Twenty-two normozoospermic donors. INTERVENTION(S):Semen samples were incubated in modified human tubal fluid (mHTF) control and in 10...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.12.024
更新日期：2014-04-01 00:00:00
abstract：:Microsurgical nonvascularized transplantation of a 1-cm segment of fallopian tube was performed using the rabbit as a model. Autograft experiments showed survival of a 1-cm tubal segment for as long as 10 months postoperatively. Allografts survived equally as well, and one rabbit became pregnant. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45691-8
更新日期：1981-08-01 00:00:00
abstract：OBJECTIVE:To assess the association between recent cigarette smoking (CS) in female and male partners and assisted reproduction technology (ART) outcomes. DESIGN:Cohort prospective study. SETTING:University ART program in Chile. PATIENT(S):One hundred sixty-six couples seeking pregnancy through ART. INTERVENTION(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.09.073
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To review the effectiveness of rectal probe electroejaculation in terms of pregnancy in treatment of anejaculatory males due to spinal cord injury. The characteristics of electroejaculates also are examined. DATA IDENTIFICATION:All English language studies reporting pregnancies as a result of electroejaculat...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：OBJECTIVE:To present an unusual side effect of therapy for adolescent menorrhagia, with commentary on management options. DESIGN:Case report. SETTING:Tertiary gynecologic center. PATIENT(S):A 13-year-old girl presenting with profuse uterine bleeding. INTERVENTION(S):Dysfunctional uterine bleeding was diagnosed, and...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.07.997
更新日期：2009-11-01 00:00:00
abstract：:Hormone patterns during 113 nonconceptual gonadotropin-induced cycles of 65 infertile anovulatory women were analyzed. All but one women ovulated, i.e., the ovulation rate was 98%. Signs of defective corpus luteum function were observed during 8 cycles, and anovulation occurred in 11 treatment cycles. The duration of ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47115-3
更新日期：1983-06-01 00:00:00
abstract：OBJECTIVE:To study the distribution of a set of polymorphic alleles of genes encoding key regulators of the menstrual cycle in cohorts of women with different levels of fertility. DESIGN:Prospective cohort study. SETTING:University hospital. PATIENT(S):Two hundred fertile women, who reported to have conceived within...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.05.048
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:To study the expression of FOXO1 and pSer256-FOXO1 parallel to Akt and pSer473-Akt in leiomyoma compared with adjacent myometrium from human uteri. DESIGN:Prospective study. SETTING:University departments. PATIENT(S):Thirty-eight cyclic and 20 menopausal women who underwent hysterectomy for benign indicati...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.07.1670
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:To determine whether there is a difference in fibrinolytic compounds in endometriotic tissue, endometrium, peritoneal fluid (PF), and plasma from women with endometriosis and in endometrium and PF from healthy women. DESIGN:Prospective study. SETTING:Two university clinics. PATIENT(S):Regularly menstruatin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00285-4
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVES:To investigate whether endometrial thickness on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. DESIGN:A retrospective study. PATIENT(S):Two hundred forty-nine women undergoing IUI cycles. SETTING:University hospital-based infertility center. INTERVENTION(S):Endom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.12.010
更新日期：2007-08-01 00:00:00
abstract：:Among 2,245 women, those who experienced a chemical pregnancy that failed to progress to a clinically recognized pregnancy or a spontaneous abortion on their first IVF cycle were more likely to discontinue IVF treatment than those whose first cycle ended before embryo transfer or who did not have a positive pregnancy ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.07.1732
更新日期：2009-04-01 00:00:00
abstract：:Progesterone (P) level and daily change in human chorionic gonadotropin (hCG) were determined in the serum of 307 patients with suspected ectopic pregnancy (EP). Of the viable intrauterine pregnancies (IUP), 99% had P values above 30 nmol/L, whereas 75% of the EP and 81% of the spontaneous abortions had P values less ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54173-9
更新日期：1991-03-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of human oviductal cells on various sperm functions in vitro. DESIGN:Controlled experimental laboratory study. SETTING:University gynecology unit. PATIENT(S):Women undergoing tubal ligation or hysterectomy and men who were visiting our subfertility clinics. INTERVENTION(S):Cocult...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00430-0
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:To examine the small antral follicle (SAF) cohort in ovaries of adult rhesus monkeys after consumption of a Western-style diet (WSD), with or without chronically elevated androgen levels since before puberty. DESIGN:Cholesterol or T (n = 6 per group) implants were placed SC in female rhesus macaques beginnin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.11.045
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To determine whether differences existed in mood and coping styles among fertile men, oligoasthenospermic men, or euspermic men whose wives were undergoing ovulation stimulation with clomiphene and IUI. DESIGN:A cross-sectional research design. SETTING:Hospital-based academic fertility clinic. PATIENT(S):3...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01511-9
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To search for mutations in the coding exons of the follistatin gene of women diagnosed with polycystic ovary syndrome (PCOS). DESIGN:Controlled clinical study. SETTING:Tertiary institutional hospital. PATIENT(S):Thirty-four women diagnosed with PCOS and 15 healthy control women. INTERVENTION(S):Whole bloo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01697-1
更新日期：2001-05-01 00:00:00
abstract：:Nonsurgical recovery of a preimplantation conceptus from the uterus of a fertile donor woman with transfer to an infertile recipient woman and subsequent pregnancy has been described previously. In this report, we describe the performance of 56 nonsurgical uterine lavages, recovery of 23 ova, and transfer of 17 ova wi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.01.038
更新日期：2006-09-01 00:00:00
abstract：:Seven nonionic detergents of the Igepal CO series differing in molecular size and including nonoxynol-9 and a representative anionic (SDS) and cationic (Cepacol) detergent were tested as to their relative cytotoxicity. The biologic effects of these detergents on human W1--38 fibroblasts (DNA and glycosaminoglycans syn...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
