Abstract:
:Seven nonionic detergents of the Igepal CO series differing in molecular size and including nonoxynol-9 and a representative anionic (SDS) and cationic (Cepacol) detergent were tested as to their relative cytotoxicity. The biologic effects of these detergents on human W1--38 fibroblasts (DNA and glycosaminoglycans synthesis) and on the motility of human spermatozoa were studied. The relative order of cytotoxicities for both fibroblasts and spermatozoa was cationic greater than nonionic greater than anionic. The concentration of nonoxynol-9-inhibiting fibroblast activity was approximately 30 times less than the amount needed to immobilize spermatozoa. It is concluded that CO-630, used as a source of nonoxynol-9, is the most effective polymer to inhibit spermatozoa and also fibroblasts.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Chvapil M,Ulreich JB,O'Dea K,Betts K,Droegemueller Wsubject
Has Abstractpub_date
1980-05-01 00:00:00pages
521-5issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(16)44718-7journal_volume
33pub_type
杂志文章abstract::To determine characteristics associated with regretting sterilization that can be determined preoperatively, we analyzed data from the Collaborative Review of Sterilization (CREST), a multicenter, prospective, observational study. Of 5022 women, 2.0% regretted having had a tubal sterilization at 1 year after the proce...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48746-7
更新日期:1985-08-01 00:00:00
abstract::"To understand the actual world as it is, not as we should wish it to be, is the beginning of wisdom." - Bertrand Russell. ...
journal_title:Fertility and sterility
pub_type: 社论
doi:10.1016/j.fertnstert.2018.06.007
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To determine the degree of improvement in semen parameters after finasteride discontinuation. DESIGN:A prospective database of men presenting for a fertility evaluation was analyzed for semen and hormone parameters before and after discontinuation of finasteride. SETTING:A male infertility specialty clinic....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.07.2000
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To examine the factors influencing the development of adhesions after laparoscopic myomectomy (LM) and the efficacy of adhesion-preventing agents. DESIGN:Prospective nonrandomized study. SETTING:University-affiliated hospital. PATIENT(S):Three hundred seventy-two patients who underwent LM alone by the same...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2007.05.021
更新日期:2008-05-01 00:00:00
abstract::This statement explores the implications of reproduction by single individuals, unmarried heterosexual couples, and gay and lesbian couples, and concludes that ethical arguments supporting denial of access to fertility services on the basis of marital status or sexual orientation cannot be justified. This document rep...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.08.042
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To measure activin A concentrations in uterine washing fluid collected from women with couple infertility undergoing intrauterine insemination (IUI). DESIGN:Retrospective case-control study. SETTING:Tertiary university center for women's care. PATIENT(S):Fifty women, of whom 25 became pregnant after up to ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.12.125
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To establish a quality control method to monitor and eventually to standardize the subjective assessment of sperm motility in conventional semen analysis. DESIGN:Quality control study running over 2 years. SETTING:University infertility clinic and andrology laboratory. PATIENT(S):Randomly chosen patients a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81455-0
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:To summarize current understanding of the effects of novel and prior coronaviruses on human reproduction, specifically male and female gametes, and in pregnancy. DESIGN:Review of English publications in PubMed and Embase to April 6, 2020. METHOD(S):Articles were screened for reports including coronavirus, r...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.04.025
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To determine whether self-selected women with polycystic ovary syndrome (PCOS) are abnormal compared with a control population. DESIGN:Case-control. SETTING:Support group meeting organized and initiated by patients. PATIENT(S):Forty-five self-selected women with PCOS and 80 control women. INTERVENTION(S):...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)03153-9
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:To determine the effects of myo-inositol on oocyte quality in polycystic ovary syndrome (PCOS) patients undergoing intracytoplasmic sperm injection (ICSI) cycles. DESIGN:A prospective, controlled, randomized trial. SETTING:Assisted reproduction centers. PATIENT(S):Sixty infertile PCO patients undergoing ov...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2008.01.088
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To determine whether serum interleukin (IL)-8 concentration can be measured in patients with ovarian endometrioma and whether this measurement is a useful tool in diagnosing this disease. DESIGN:A controlled clinical study and an in vitro study. SETTING:Department of Obstetrics and Gynecology, Tottori Unive...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.07.1355
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To describe the option of ultrasonographic-guided percutaneous transabdominal puncture for ovum pickup in a rare case of Rokitansky syndrome with subcostal located ovaries and a right single kidney. DESIGN:Technique and instrumentation. SETTING:A university-based hospital IVF and Reproductive Medicine Unit....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.05.039
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To describe a case of uterine pseudoaneurysm after laparoscopic myomectomy in a 36-year-old woman. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 36-year-old woman, 3 months after laparoscopic myomectomy, presenting with an intrauterine hypoechoic lesion measuring 5 cm in diameter. INTERVEN...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.09.019
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To elucidate the role of vitamin D in reproduction by examining the relationship between recipient vitamin D levels and pregnancy rates in donor-recipient IVF cycles. DESIGN:Retrospective cohort study. SETTING:Academic tertiary care center. PATIENT(S):Ninety-nine recipients of egg donation at University of...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.10.008
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To determine the possible effect of freezing on sperm escape force as measured by laser trap. DESIGN:Controlled clinical study. SETTING:Normal volunteers, academic setting. PATIENTS:Normal, healthy volunteers. INTERVENTION:Sperm selection, freezing and thawing. Measurement of relative (sperm) escape force...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Gene products estrogen receptor alpha, progesterone receptor-A, retinoid X receptor alpha, insulin-like growth factor-II, insulin-like growth factor I receptor beta, platelet-derived growth factor, epithelial growth factor receptor, and BCL-2 were examined by immunohistochemistry with the aid of a tissue microarray fr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.104
更新日期:2007-07-01 00:00:00
abstract::Two-cell mouse embryos were cultured in Ham's F-10 medium (Gibco, Grand Island, NY) supplemented with various concentrations of transferrin, insulin, epidermal growth factor, platelet-derived growth factor, or fibroblast growth factor. Rates of development and the cell numbers per blastocyst were compared between embr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54082-5
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To investigate the use of preimplantation genetic diagnosis (PGD) as a method for increasing pregnancy success rates in patients at high risk for aneuploidy. DESIGN:Literature review and discussion of current evidence. CONCLUSION(S):Preimplantation genetic diagnosis selects euploid embryos for transfer in a...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2005.06.045
更新日期:2006-01-01 00:00:00
abstract::This article highlights a comprehensive range of research investigations which are required to clarify the relationships between the symptom of excessively heavy menstrual bleeding and different disorders of systemic hemostasis and their management. The need for these investigations was stimulated by an international ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2005.07.1268
更新日期:2005-11-01 00:00:00
abstract::The objective of this retrospective cohort study was to assess the potential effects of preconceptional short-term exposure to particulate air pollution in a real-world situation on pregnancy outcome in infertile women evaluating the possible role of IVF/embryo transfer treatment on this outcome using women who had co...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.06.031
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To see if clinicians' impressions were influenced by expert opinion on patient selection criteria that influence magnetic resonance-guided focused ultrasound (MRgFUS) leiomyoma treatment. DESIGN:Survey-based study. SETTING:First international symposium devoted to MRgFUS, "MRgFUS 2008," October 6-7, 2008, Wa...
journal_title:Fertility and sterility
pub_type:
doi:10.1016/j.fertnstert.2009.02.083
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To determine the effects of smoking on eggs and subsequent embryo development by maternal exposure to cigarette smoke. DESIGN:Mice were exposed to cigarette smoke or cigarette smoke condensate (CSC) for 4 weeks and then examined for development and telomere function of embryos in vitro after fertilization. I...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.07.1781
更新日期:2009-10-01 00:00:00
abstract::There is good evidence of an associated abnormality in testicular hormone production and spermatogenesis in some men with varicoceles. This abnormality can be demonstrated with dynamic tests of the hypothalamic-pituitary-testicular axis and by measuring seminal plasma androgen levels. A high proportion of oligozoosper...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)59700-3
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between carriage of BRCA1/2 mutations and ovarian performance, as demonstrated by in vitro fertilization (IVF) outcomes. DESIGN:Retrospective cohort study. SETTING:Two tertiary IVF centers. PATIENT(S):BRCA mutation carriers undergoing IVF for preimplantation genetic diagnosis (P...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2015.07.1162
更新日期:2015-11-01 00:00:00
abstract::This study, which is concerned with establishing clinically relevant corridors defining normal progesterone (P) levels in saliva, has addressed some of the shortcomings associated with previous equivalent studies (e.g., limited data, inadequately monitored ovulations, inadequately defined subjects). A sensitive, direc...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60366-7
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent embryo development. DESIGN:Animal study. SETTING:University laboratory. ANIMAL(S):CD-1 mice. INTERVENTION(S):Immature oocytes were arrested meiotically in medium containing a specific phosphodiester...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.03.041
更新日期:2009-05-01 00:00:00
abstract::The interaction between human uterine secretions and human spermatozoa was studied. Secretions were obtained by washing the endometrial surfaces of normal uteri removed at surgery and collecting uterine fluid by incubating Millipore chambers in the uteri of volunteers. A microtechnique was devised for conducting metab...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)45259-3
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:To investigate the role(s) of colony-stimulating factor 1 (CSF-1) on the development of early endometriosis in a murine model by comparing rate of lesion formation in mice [1] homozygous for a CSF-1 mutation versus syngeneic controls and [2] after treatment with imatinib, a commercially available tyrosine kin...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.09.050
更新日期:2010-01-01 00:00:00
abstract::A case of intramural but not interstitial pregnancy, established after IVF/ET, is described. The etiologic, diagnostic, and therapeutic aspects of this clinical dilemma are discussed. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54804-3
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Formin-2 (Fmn2) mutant mice produce oocytes with meiosis I arrest. Our aim was to describe the human FORMIN-2 (FMN2) gene and to identify DNA sequence polymorphisms in patients with unexplained infertility and multiple failed IVF cycles. DESIGN:Institutional review board-approved observational case-control s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.10.051
更新日期:2005-05-01 00:00:00